TOP 10 Medical News Stories
Mon March 30 – 10 Stories of The Day!
30 Mar, 2020 | 02:30h | UTC
2 – Management of Critically Ill Adults With COVID-19 – JAMA
Editorial: Toward Universal Deployable Guidelines for the Care of Patients With COVID-19
Original Guideline: Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) – Intensive Care Medicine AND Infographics: The Surviving Sepsis Campaign Rapid Guidelines on the Management of Critically Ill Adults with COVID-19
Related Summary: Surviving Sepsis Campaign: COVID-19 Recommendations – CanadiEm
Related Guideline: COVID-19 rapid guideline: critical care – National Institute for Health and Care Excellence
3 – Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA
Editorial: Convalescent Plasma to Treat COVID-19: Possibilities and Challenges
Commentaries: A new report raises hope that the blood of recovered patients can help treat severe coronavirus cases – Business Insider AND Plasma transfusion shows promise for COVID-19 treatment, says China study – UPI
See also: Investigational COVID-19 Convalescent Plasma – Emergency INDs – U.S. Food & Drug Administration
4 – COVID-19: Controversies on the Use of Face Masks
- Would everyone wearing face masks help us slow the pandemic? – Science
- Not wearing masks to protect against coronavirus is a ‘big mistake,’ top Chinese scientist says – Science
- More Americans Should Probably Wear Masks for Protection – The New York Times
- Experts say face masks can help slow COVID-19, despite previous claims – New York Post
- Coronavirus: Chinese scientist advises people in Europe, US to wear face masks in public – South China Morning Post
Related Guidance: WHO Recommendations on when and how to use masks – World Health Organization AND Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention
5 – N95 Re-Use Instructions – SAGES
Related: Conserving Supply of Personal Protective Equipment—A Call for Ideas – JAMA AND N95 mask can be decontaminated without decreasing filtration efficiency – Stanford Medicine
Related Guidelines: HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 – American College of Cardiology AND The Renal Association, UK position statement on COVID-19 and ACE Inhibitor/Angiotensin Receptor Blocker use AND Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers – European Society of Cardiology
7 – A War on Two Fronts: Cancer Care in the Time of COVID-19 – Annals of Internal Medicine
Related Guidelines: COVID-19 rapid guideline: delivery of systemic anticancer treatments – National Institute for Health and Care Excellence AND Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal – Journal of the National Comprehensive Cancer Network
8 – Primary care & Coronavirus (COVID 19): key guidance, information and support – Medium
Related: Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ AND Covid-19: a remote assessment in primary care
9 – Potential Effects of Coronaviruses on the Cardiovascular System: A Review – JAMA Cardiology
Editorial: Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality
Related Articles: Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China – JAMA Cardiology AND Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) – JAMA Cardiology
Commentary: A Heart Attack? No, It Was the Coronavirus – The New York Times
10 – Coronavirus Disease (COVID-19) Updates / 30 March 2020 Edition
30 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Fri March 27 – 10 Stories of The Day!
27 Mar, 2020 | 04:25h | UTC
1 – Report 12: The Global Impact of COVID-19 and Strategies for Mitigation and Suppression – Imperial College London
See also: Summary
Commentaries: Coronavirus: ‘Act early to save more than 30 million lives’ – BBC AND Study sees ‘severe and acute’ emergency for world in coronavirus pandemic – Reuters
Preprint: Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilator days and deaths by US state in the next 4 months (PDF)
Commentaries: A new report warns that the coronavirus pandemic will overwhelm US hospitals and kill 81,000 people by July – Business Insider AND Coronavirus could kill 81,000 in U.S., subside in June – Washington University analysis – Reuters
3 – Perspectives on the Pandemic with Dr. John Ioannidis
Related Article: Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures (free study and commentaries)
See also: How to model a pandemic – The Conversation AND Coronavirus exposes the problems and pitfalls of modelling – The Guardian
5 – Managing mental health challenges faced by healthcare workers during covid-19 pandemic – The BMJ
Related Study: Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019 – JAMA Network Open AND Commentary: Survey Finds COVID-19 Takes Heavy Psychological Toll on Health Care Workers – Psychiatric News Alert
See also: COVID-19: Updates for Radiologists
7 – Recommendation: Unproven Therapies for COVID-19 | March 24, 2020 – BC Centre for Disease Control
10 – Coronavirus Disease (COVID-19) Updates / 27 March 2020 Edition
27 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Thu March 26 – 10 Stories of The Day!
26 Mar, 2020 | 02:30h | UTC
See also: Summary
Commentaries: Initial success for COVID-19 social distancing in China – Imperial College London AND China shows way to ease lockdowns before vaccine, says report – The Guardian AND When can we let up? Health experts craft strategies to safely relax coronavirus lockdowns – STAT
Related: What China’s coronavirus response can teach the rest of the world – Nature AND Locked-down no longer, China’s Hubei begins return to normal – Reuters AND The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study – The Lancet Public Health
2 – The effect of human mobility and control measures on the COVID-19 epidemic in China – Science
News Release: Travel restrictions are most useful in the early and late phase of an epidemic – University of Oxford
3 – What do we know about the risk of dying from COVID-19? – Our World in Data
Related: Global Covid-19 Case Fatality Rates – Centre for Evidence-Based Medicine, University of Oxford (free)
4 – Studies: Cardiac Injury Associated to Increased Mortality in Hospitalized Patients With COVID-19
- Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China – JAMA Cardiology AND Commentaries: Cardiac injury linked to increased mortality in COVID-19 – MedicalXpress AND Cardiac injury in COVID-19 patients associated with higher in-hospital mortality – Cardiovascular Business AND Cardiac Injury and Mortality in Hospitalized COVID-19 Patients – American College of Cardiology
- Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): Evidence from a meta-analysis – Progress in Cardiovascular Diseases AND Commentary: Meta-Analysis on Troponin I in Patients With Coronavirus – Latest in Cardiology
Commentary: Study: An aspirin a day does not keep dementia at bay – American Academy of Neurology (free)
“Very important article about viral shedding. Spoiler alert: quarantine may need to be much longer than 14 days. Virus is detectible in feces for up to 5 weeks. Caveat: virus not necessarily viable” (via @figgyjam see Tweet)
Commentary: Low risk of coronavirus spreading through tears – American Academy of Ophthalmology
Commentaries: Coronavirus: household cleaning products can kill the virus – an expert on which ones to use – The Conversation AND One graphic shows how long the coronavirus lives on surfaces like cardboard, plastic, and steel – Business Insider
Related Study: Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 – New England Journal of Medicine
10 – Coronavirus Disease (COVID-19) Updates / 26 March 2020 Edition
26 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Wed March 25 – 10 Stories of The Day!
25 Mar, 2020 | 03:08h | UTC
News Release: New WHO recommendations to prevent tuberculosis aim to save millions of lives – World Health Organization (free)
See also: Handbook (free)
Commentary: Don’t forget chronic lung and immune conditions during covid-19, says WHO – The BMJ (free)
Commentaries: Singapore modelling study estimates impact of physical distancing on reducing spread of COVID-19 – The Lancet AND Scientific and ethical basis for social-distancing interventions against COVID-19 – The Lancet Infectious Diseases AND Study: Social distancing might reduce COVID-19 spread by as much as 99% – UPI
3 – Interim Guidance for Healthcare Providers during COVID-19 Outbreak – American Heart Association (free PDF)
News Release: Interim guidance to reduce COVID-19 transmission during resuscitation care – American Heart Association (free)
See also: COVID-19: Updates for Cardiologists
4 – Coronavirus Disease 2019 (COVID-19) and Cardiovascular Disease – Circulation
See also: COVID-19: Updates for Cardiologists
5 – Effect of gastrointestinal symptoms on patients infected with COVID-19 – Gastroenterology (PDF)
See also: COVID-19: Updates for Gastroenterologists
7 – Report: N95 mask can be decontaminated without decreasing filtration efficiency – Stanford Medicine
“Stanford: N95 masks can be decontaminated without decreasing filtration efficiency using 70C heat for 30 min. Alcohol and bleach should not be used.” (via @CMichaelGibson see Tweet)
8 – Nonalcoholic Steatohepatitis: A Review – JAMA (free for a limited period)
Related Podcast: Nonalcoholic Steatohepatitis: The Primary Care Perspective – JAMA (free)
Commentaries: Polyps and Colorectal Cancer risk – Karolinska Institutet (free) AND Risk of colorectal cancer incidence and mortality after polypectomy – ESMO (free)
10 – Coronavirus Disease (COVID-19) Updates / 25 March 2020 Edition
25 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Tue March 24 – 10 Stories of The Day!
24 Mar, 2020 | 09:58h | UTC
Commentary: Life, or death? Experts guide pandemic medical equipment decisions – CIDRAP
Related Perspective: The Toughest Triage — Allocating Ventilators in a Pandemic – New England Journal of Medicine
Commentary: Study Calculates Just How Much Age, Medical Conditions Raise Odds Of Severe COVID-19 – NPR (free)
3 – Chloroquine for COVID-19: Cutting Through the Hype – The Scientist
Related Guideline: Infection Prevention and Control guidance for Long-Term Care Facilities in the context of COVID-19 – World Health Organization (PDF)
Related Article: COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020 – CDC Morbidity and Mortality Weekly Report
Related Perspective: The Coronavirus’s Rampage Through a Suburban Nursing – The New York Times
5 – COVID-19: What About Prisons?
- Prisons and custodial settings are part of a comprehensive response to COVID-19 – The Lancet Public Health
- Preventing COVID-19 outbreak in prisons: a challenging but essential task for authorities – WHO/Europe
- COVID-19: prisons and other prescribed places of detention guidance – Public Health England
- A coronavirus outbreak in jails or prisons could turn into a nightmare
- ‘A Storm Is Coming’: Fears of an Inmate Epidemic as the Virus Spreads in the Jails – The New York Times
- ‘Everyone will be contaminated’: prisons face strict coronavirus controls – The Guardian
6 – FDA Recommendations for Conserving Medical Supplies
- Ventilator Supply Mitigation Strategies: Letter to Health Care Providers – U.S. Food & Drug Administration
- Medical Glove Conservation Strategies: Letter to Health Care Providers – U.S. Food & Drug Administration
- Surgical Mask and Gown Conservation Strategies – Letter to Healthcare Providers – U.S. Food & Drug Administration
- See also: Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention (free)
7 – Anti-arrhythmic properties of non-antiarrhythmic medications – Pharmacological Research (free)
8 – Association Between Surgical Approach and Major Surgical Complications in Patients Undergoing Total Hip Arthroplasty – JAMA (free for a limited period)
Editorial: Controversies in Hip Arthroplasty: Using Registries to Answer Difficult Questions (free for a limited period)
Commentary: Complication Rates Vary Between Hip Surgery Approaches – MedicalResearch.com (free)
9 – Obesity Treatment Among Adolescents: A Review of Current Evidence and Future Directions – JAMA Pediatrics (free for a limited period)
10 – Coronavirus Disease (COVID-19) Updates / 23 March 2020 Edition
23 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Mon March 23 – 10 Stories of The Day!
23 Mar, 2020 | 02:08h | UTC
Infographics: The Surviving Sepsis Campaign Rapid Guidelines on the Management of Critically Ill Adults with COVID-19 (free)
See also: COVID-19: Updates for Critical Care and Emergency Physicians (free resources)
Related Study: COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020 – CDC Morbidity and Mortality Weekly Report (free)
“Introduction of COVID-19 into a long-term residential care facility in Washington resulted in cases among 81 residents, 34 staff members, and 14 visitors; 23 persons died” (from CDC)
3 – COVID-19 rapid guideline: critical care – National Institute for Health and Care Excellence (NICE)
See also: COVID-19: Updates for Critical Care and Emergency Physicians (free resources)
See also: COVID-19: Updates for Nephrologists (free resources)
See also: COVID-19: Updates for Oncologists & Hematologists (free resources)
6 – Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial – medRxiv
7 – Global Covid-19 Case Fatality Rates – Centre for Evidence-Based Medicine, University of Oxford (free)
8 – Position Statement: Loss of sense of smell as marker of COVID-19 infection – ENT-UK
See also: There’s An Unexpected Loss Of Smell And Taste In Coronavirus Patients – Forbes (free) AND If you’ve lost your sense of smell or taste, you could be a ‘hidden carrier’ of the coronavirus – Business Insider (free)
Related Opinion Piece: A fiasco in the making? As the coronavirus pandemic takes hold, we are making decisions without reliable data – STAT (free)
Rebuttal 1: We know enough now to act decisively against Covid-19. Social distancing is a good place to start – STAT (free)
Rebuttal 2: A Rebuttal to “A Fiasco in the Making?” – Hilda Bastian (Free)
10 – Coronavirus Disease (COVID-19) Updates / 23 March 2020 Edition
23 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Fri March 20 – 10 Stories of The Day!
20 Mar, 2020 | 11:12h | UTC
Commentary: CVD in the Setting of COVID-19: Considerations to Prepare Patients, Providers, Health Systems – American College of Cardiology (free)
3 – Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention (free)
4 – COVID-19 Prioritization of Diagnostic Testing – Infectious Diseases Society of America (free PDF)
Summary: IDSA Statement On COVID-19 Testing Recommendations – Infectious Diseases Society of America (free)
5 – New Preliminary Studies with Hydroxychloroquine:
New Clinical Trial: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial – International Journal of Antimicrobial Agents (free PDF)
This was an open-label study with only 42 patients without patient-relevant endpoints. The 6 patients that received Hydroxychloroquine + Azithromycin achieved more efficient virus elimination than control patients.
New in Vitro Study: Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro – Cell Discovery (free)
Related Articles: In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) – Clinical Infectious Diseases (free PDF) AND New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? – International Journal of Antimicrobial Agents (free) AND A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 – Journal of Critical Care (free) AND Of chloroquine and COVID-19 – Antiviral Research (free)
6 – Management of Kidney Stones in 2020 – JAMA (free for a limited period)
Related Guidelines: Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence (free) AND Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians (free) AND Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement – Journal of Nephrology (free) AND Medical Management of Kidney Stones: AUA Guideline (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART II (free) AND The Urological Association of Asia clinical guideline for urinary stone disease – International Journal of Urology (free)
Commentary: FDA advises stopping SGLT2 inhibitor treatment prior to surgery – The Hospitalist (free)
“- Canagliflozin, dapagliflozin, and empagliflozin should each be discontinued at least three days before scheduled surgery.
– Ertugliflozin should be discontinued at least four days before scheduled surgery.
– Blood glucose levels should be carefully monitored after discontinuation of the SGLT2 inhibitor and appropriately managed before surgery.”
Editorial: Suicide and the media: reporting could cost lives (free)
Commentaries: Responsible communication on suicide in the media is essential if we want to be serious about tackling the stigma surrounding suicide – The BMJ Opinion (free) AND Suicide and the media: reporting could cost lives – University of Bristol (free) AND Media reports of celebrity suicide linked to increased suicide rates – BMJ (free)
10 – Coronavirus Disease (COVID-19) Updates / 20 March 2020 Edition
20 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Thu March 19 – 10 Stories of The Day!
19 Mar, 2020 | 11:07h | UTC
1 – Coronavirus Update with Anthony Fauci, MD – March 18, 2020 – JAMA (free)
2 – Surgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: What Works Best to Ease the Pain of Sciatica? – HealthDay News (free)
Editorial: Covid-19 — The Search for Effective Therapy (free)
See also: Interview with Dr. Eric Rubin and Dr. Lindsey Baden on new research on possible treatments for Covid-19 – New England Journal of Medicine (free)
4 – SARS-CoV-2 Infection in Children – New England Journal of Medicine (free)
Related Articles: Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China – Peditrics (free) Detection of Covid-19 in Children in Early January 2020 in Wuhan, China – New England Journal of Medicine (free) AND Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children – The Pediatric Infectious Diseases Journal (free PDF) AND Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding – Nature Medicine (free)
Commentaries: Study from The American Journal of Gastroenterology Reveals Diarrhea is a Prominent Symptom of COVID-19 – American College of Gastroenterology (free) AND Diarrhea a key symptom in 1 of 4 COVID-19 patients, study finds – UPI (free)
7 – Management of ANCA associated vasculitis – The BMJ (free)
8 – Confirmatory Trial for Drug to Prevent Preterm Birth Finds No Benefit, So Why Is It Still Prescribed? – JAMA (free for a limited period)
Original Article: Randomized Trial: Injectable 17-α-hydroxyprogesterone Not Effective for the Prevention of Recurrent Preterm Birth (free study and commentaries)
Related Study: A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine (free)
9 – Robotic Inguinal vs Transabdominal Laparoscopic Inguinal Hernia Repair: The RIVAL Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited Commentary: Robotics vs Laparoscopy—Are They Truly Rivals? – JAMA Surgery (free for a limited period)
Author Interview: Robotic Approach vs Traditional Laparoscopic Approach and Postoperative Outcomes (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 19 March 2020 Edition
19 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Wed March 18 – 10 Stories of The Day!
18 Mar, 2020 | 09:58h | UTC
2 – 2020 Alzheimer’s disease facts and figures – Alzheimer’s & Dementia (free)
Summary: Report 9 – Imperial College London (free)
Commentaries: US, UK coronavirus strategies shifted following UK epidemiologists’ ominous report – CNN (free) AND New Analysis Suggests Months Of Social Distancing May Be Needed To Stop Virus – NPR (free)
“…in an unmitigated epidemic, we would predict approximately 510,000 deaths in GB and 2.2 million in the US, not accounting for the potential negative effects of health systems being overwhelmed on mortality.”
Commentaries: New coronavirus stable for hours on surfaces – NIH News Releases (free) AND How Long Will Coronavirus Live on Surfaces or in the Air Around You? – The New York Times (10 articles per month are free) AND New coronavirus can persist in air for hours and on surfaces for days: study – Reuters (free)
5 – Consequences of Undervaccination – Measles Outbreak, New York City, 2018-2019 – New England Journal of Medicine (link to abstract – $ for full-text)
6 – Safety and immunogenicity of a tetravalent dengue vaccine in children aged 2–17 years: a randomised, placebo-controlled, phase 2 trial – The Lancet (link to abstract – $ for full-text)
7 – Association Between Proton Pump Inhibitor Use and Risk of Fracture in Children – JAMA Pediatrics (free for a limited period)
Commentary: Proton-Pump Inhibitors: Small Increased Risk of Fractures in Children – MedicalResearch.com (free)
Commentaries: Artificial intelligence-derived imaging biomarkers to improve population health – The Lancet Digital Health (free) AND Artificial Intelligence Predicts Heart Disease Risk from CT Scans – NIH Research Matters (free)
9 – Early prediction of circulatory failure in the intensive care unit using machine learning – Nature Medicine (link to abstract – $ for full-text)
Commentary: Circulatory failure is predictable – ETH Zurich (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 18 March 2020 Edition
18 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Tue March 17 – 10 Stories of The Day!
17 Mar, 2020 | 08:55h | UTC
Commentaries: 80% of COVID-19 spreads from people who don’t know they are sick – UPI (free) AND Coronavirus Is Hiding in Plain Sight – The New York Times (10 articles per month are free)
Related: COVID-19: Who Is Infectious? – Forbes (free) AND Infected people without symptoms might be driving the spread of coronavirus more than we realized – CNN (free)
2 – ‘A ticking time bomb’: Scientists worry about coronavirus spread in Africa – Science (free)
Related: Managing COVID-19 in Low- and Middle-Income Countries – JAMA (free) AND Inside the Efforts to Prepare African Countries for COVID-19 – TIME (free) AND Looming threat of COVID-19 infection in Africa: act collectively, and fast – The Lancet (free) AND Is the Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic? – lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future – International Journal of Infectious Diseases (free PDF)
3 – Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel – Radiology (free)
Commentary: Experts stress radiology preparedness for COVID-19 – Radiology Society of North America (free)
Commentary: Children with COVID-19 Impacted Less Severely Than Adults: Study – American Academy of Pediatrics (free)
Commentary: Study questions role of antibiotics in kids’ pneumonia – CIDRAP (free)
6 – Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Dual therapy for afib after PCI may reduce bleeding risk better than triple therapy – ACP Internist (free) AND Dual therapy reduces risk for bleeding better than triple therapy for patients with atrial fibrillation – American College of Physicians (free)
Related Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI – European Heart Journal (free) AND Meta-analysis comparing double versus Triple Anti-thrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease – The American Journal of Cardiology (free)
See also: Episode List
8 – Tinnitus – JAMA (free for a limited period)
Related Guideline: Tinnitus: assessment and management – National Institute for Health and Care Excellence (free)
9 – Development and Validation of a Penicillin Allergy Clinical Decision Rule – JAMA Internal Medicine (free for a limited period)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 17 March 2020 Edition
17 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Mon March 16 – 10 Stories of The Day!
16 Mar, 2020 | 08:04h | UTC
Related: Severe SARS-CoV-2 Infections: Practical Considerations and Management Strategy for Intensivists (free studies and reviews)
Related: The psychological impact of quarantine and how to reduce it: rapid review of the evidence – The Lancet (free) AND Behavioural scientists form new front in battle against coronavirus – The Guardian (free)
“Minimize watching, reading or listening to news that causes you to feel anxious or distressed; seek information only from trusted sources and mainly to take practical steps to prepare your plans and protect yourself and loved ones.”
Related Video: Coronavirus in Italy – Report From The Front Lines – JAMA (free)
Commentary: COVID-19 appears less severe in children – Wolters Kluwer Health (free)
Related: A Review of Coronavirus Disease-2019 (COVID-19) – Indian Journal of Pediatrics (free) AND Detection of Covid-19 in Children in Early January 2020 in Wuhan, China – New England Journal of Medicine (free) AND Coronavirus with a baby: what you need to know to prepare and respond – The Conversation (free)
Commentaries: How Does The Coronavirus Affect Kids? What We Know So Far About COVID-19 In Children – Forbes (free) AND Coronavirus study finds children with COVID-19 show milder symptom pattern – Reuters (free)
“Children infected with the #COVID19 outbreak coronavirus, SARS-CoV-2, show mild symptoms but prolonged shedding of viral RNA in feces, suggesting that the fecal–oral route might play a role in virus transmission #CORONAVIRUS” (via @NatureMedicine see Tweet)
6 – COVID-19 Airway Management Principles – Intensive Care Society; The Faculty of Intensive Care Management; Association of Anaesthetists; and Royal College of Anaesthetists (free)
Summary: COVID-19 Airway management principles (free PDF)
7 – When Guidelines Recommend Shared Decision-making – JAMA (free)
Author Interview: When Guidelines Recommend Shared Decision-making (free audio)
8 – Association of Functional, Cognitive, and Psychological Measures With 1-Year Mortality in Patients Undergoing Major Surgery – JAMA Surgery (free for a limited period)
9 – The Palliative Care of Patients with Incurable Cancer – Deutsches Ärzteblatt international (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 16 March 2020 Edition
16 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Fri March 13 – 10 Stories of The Day!
13 Mar, 2020 | 08:04h | UTC
2 – Canadian Cardiovascular Society/Canadian Cardiac Transplant Network Position Statement on Heart Transplantation: Patient Eligibility, Selection, and Post-Transplantation Care – Canadian Journal of Cardiology (free for a limited period)
3 – Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis – Canadian Journal of Cardiology (free for a limited period)
4 – 5 Ways Research Could Save the NHS Money – NIHR Highlight (free)
Commentaries: A cure for HIV: how would we know? – The Lancet HIV (free) AND Second patient has been cured of HIV, study suggests – The Lancet (free) AND Second Patient Cured of HIV Still Clear – Science-Based Medicine (free) AND Second patient cured of HIV, say doctors – BBC (free)
7 – Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention – JAMA Psychiatry (free for a limited period)
Author Interview: Prevention of Psychosis—Advances in Detection, Prognosis, and Intervention (free audio)
Summary: Omega-3 intake for cardiovascular disease – Cochrane Library (free)
Author Interview: Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (free)
Commentary: Omega-3s Show No Overall Benefits for Heart Health or Cancer Prevention – The New York Times (free)
9 – Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials – British Journal of Cancer (link to abstract – $ for full-text)
Commentary: Omega-3 fats do not protect against cancer – University of East Anglia (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 13 March 2020 Edition
13 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Thu March 12 – 10 Stories of The Day!
12 Mar, 2020 | 10:42h | UTC
1 – ASPEN Consensus Recommendations for Refeeding Syndrome – Nutrition in Clinical Practice (free)
2 – Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia Syndrome (POTS) and Related Disorders of Chronic Orthostatic Intolerance – Canadian Journal of Cardiology (free for a limited period)
3 – Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Oxygen Therapy in ARDS (free)
Related Randomized Trial: Similar Outcomes with Conservative Oxygen Therapy vs. Usual Oxygen Therapy During Mechanical Ventilation (link to abstract and commentaries)
4 – Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Aspirin Use Associated with Reduced Hepatocellular Carcinoma and Liver-Related Mortality – NEJM Journal Watch (free)
Invited Commentary: Are three drugs for malaria better than two? – The Lancet (free)
8 – “Less is More” in mechanical ventilation – Intensive Care Medicine (free)
9 – Alcoholics Anonymous and other 12‐step programs for alcohol use disorder – Cochrane Library (free)
Author Interview: Alcoholics Anonymous and other 12-step programs for alcohol use disorder (free)
News Release: New Cochrane Review finds Alcoholics Anonymous and 12-Step Facilitation programs help people to recover from alcohol problems (free)
Commentaries: A new, big review of the evidence found that Alcoholics Anonymous works — for some – Vox (free) AND Alcoholics Anonymous validated by meta-analysis: ‘It absolutely does work’ – Stanford Medicine (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 12 March 2020 Edition
12 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Wed March 11 – 10 Stories of The Day!
11 Mar, 2020 | 10:24h | UTC
News Release: AHRQ Report Reviews 47 Practices To Improve Patient Safety – Agency for Healthcare Research and Quality (free)
News Release: COVID-19: IFRC, UNICEF and WHO issue guidance to protect children and support safe school operations – World Health Organization (free)
See also: Latest articles, guidelines and updates on the COVID-19 Outbreak (several free resources – updated daily)
3 – Tinnitus: assessment and management – National Institute for Health and Care Excellence (free)
6 – Safety of ceftriaxone in paediatrics: a systematic review – Archives of Disease in Childhood (free)
7 – Effectiveness and Safety of Apixaban Compared With Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Choosing a DOAC? Apixaban May Have an Edge Over Rivaroxaban – TCTMD (free) AND Apixaban Might Be Safer and More Effective Than Rivaroxaban for Atrial Fibrillation – NEJM Journal Watch (free)
8 – Immunogenicity, Safety, and Efficacy of a Standalone Universal Influenza Vaccine, FLU-v, in Healthy Adults: A Randomized Clinical Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Is a ‘Universal’ Flu Vaccine on the Horizon? – HealthDay (free) AND Adjuvanted FLU-v Vaccine Immunogenic in Healthy Adults – MPR (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 11 March 2020 Edition
11 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Tue March 10 – 10 Stories of The Day!
10 Mar, 2020 | 10:48h | UTC
News Release: Better lifestyle habits are useful additions to optimize management of atrial fibrillation – American Heart Association (free)
2 – Screening for atrial fibrillation: a call for evidence – European Heart Journal (free)
3 – Coronavirus (COVID-19) infection and pregnancy – Royal College of Obstetricians & Gynaecologists (free)
Related: Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow? – Acta Obstetricia et Gynecologica Scandinavica (free) AND Novel coronavirus infection and pregnancy – Ultrasound in Obstetrics and Gynecology (free) AND Preprint: CORONAVIRUS IN PREGNANCY AND DELIVERY: RAPID REVIEW AND EXPERT CONSENSUS – medRxiv (free PDF) AND Guidelines for pregnant women with suspected SARS-CoV-2 infection – The Lancet Infectious Diseases (free) AND Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know – American Journal of Obstetrics and Gynecology (free PDF) AND In the race for coronavirus vaccines, don’t leave pregnant women behind – STAT (free)
See also: Latest developments on the COVID-19/ SARS-CoV-2 Outbreak (several resources – updated daily)
Related Systematic Review: Working While Sick: A Systematic Review of Infectious Illness Presenteeism (free)
Related Study: Which healthcare workers work with acute respiratory illness? Evidence from Canadian acute-care hospitals during 4 influenza seasons: 2010–2011 to 2013–2014 – Infection Control & Hospital Epidemiology (free) AND Commentary: Sick hospital workers often expose patients to contagious illness – Reuters (free)
See also: Episode List
6 – Management of dependent use of illicit opioids – The BMJ (free)
7 – Diagnosis and Treatment of Clostridioides (Clostridium) Difficile Infection in Adults in 2020 – JAMA (free for a limited period)
Related: Clostridioides Difficile: Diagnosis and Treatments (free BMJ review and guidelines on the subject) AND Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement – Intensive Care Medicine (free)
8 – Association Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration Rate – JAMA Internal Medicine (free for a limited period)
Editorial: Continuation of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in the Face of Kidney Disease Progression—Safe and Possibly Life Saving (free for a limited period)
9 – Efficacy of Gabapentin for the Treatment of Alcohol Use Disorder in Patients With Alcohol Withdrawal Symptoms: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentaries: Drug eases withdrawal, improves abstinence in alcohol use disorder – UPI (free) AND Gabapentin Found to Work Best for Those With Severe Alcohol Withdrawal Syndrome – Psychiatric News Alert (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 10 March 2020 Edition
10 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Mon March 09 – 10 Stories of The Day!
9 Mar, 2020 | 01:06h | UTC
Original Study: Patterns of use of adjunctive therapies in patients with early moderate- severe Acute Respiratory Distress syndrome: Insights from the LUNG SAFE Study – CHEST (link to abstract – $ for full-text)
4 – Medical Reversals in Family Practice: A Review – Current Therapeutic Research (free PDF)
Related: Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
6 – Ten Simple Rules to becoming a principal investigator – PLOS Computational Biology (free)
8 – Sleep Irregularity and Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Sleep Irregularity and Risk of Cardiovascular Events – American College of Cardiology (free) AND Better Sleep Linked With Reduced Risk of CVD, Improved Weight Loss – AJMC (free) AND Poor Sleepers at Higher Risk of CVD, MESA Data Suggest – TCTMD (free) AND Irregular sleep may increase risk of cardiovascular events – Brigham and Women’s Hospital (free) AND Irregular sleep may increase risk of cardiovascular problems – Medical News Today (free)
9 – Olive Oil Consumption and Cardiovascular Risk in U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Olive Oil Consumption and Cardiovascular Risk – American College of Cardiology (free) AND Higher Olive Oil Consumption Tied to Lower CVD Risk in U.S. Adults – NEJM Journal Watch (free) AND Use Olive Oil Instead of Saturated Fats for Heart Health, Study Suggests – CardioSmart (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 9 March 2020 Edition
9 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Fri March 06 – 10 Stories of The Day!
6 Mar, 2020 | 10:42h | UTC
1 – Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ (free)
2 – 8 things to know about e-cigarettes – Public Health Matters (free)
Related Report: Vaping in England: evidence update March 2020 – Public Health England (free)
Commentary: Montelukast to Get Boxed Warning – NEJM Journal Watch (free)
5 – Effect of a Workplace-Based Multicomponent Intervention on Hypertension Control: A Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary: Blood pressure control achieved using workplace-based programs – News Medical (free)
Commentary: Expert reaction to study looking at low blood pressure and mortality in older adults – Science Media Centre (free)
7 – Validation and Utility Testing of Clinical Prediction Models: Time to Change the Approach – JAMA (free for a limited period)
8 – Diet, nutrition, and cancer risk: what do we know and what is the way forward? – The BMJ (free)
9 – News Release: Colorectal Cancer Burden Shifting to Younger Individuals – American Cancer Society (free)
Original Report: Colorectal cancer statistics, 2020 – CA: A Cancer Journal for Clinicians (free)
Commentary: Half of new colon and rectal cancer diagnoses are now in people age 66 and younger, report finds – CNN (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 6 March 2020 Edition
6 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Thu March 05 – 10 Stories of The Day!
5 Mar, 2020 | 10:33h | UTC
1 – Joint international consensus statement for ending stigma of obesity – Nature Medicine (free)
Commentary: Scientific community pledges to end obesity stigma – King’s College London (free)
Related Report: Obesity: Health and Economic Consequences of an Impending Global Challenge – The World Bank (free)
See also: Updated WHO Fact Sheet for World Obesity Day: Obesity and overweight – World Health Organization (free)
2 – Treatment of Highly Drug-Resistant Pulmonary Tuberculosis – New England Journal of Medicine (free)
Visual Abstract: Treatment of Highly Drug-Resistant Pulmonary TB (free)
Commentary: New TB drug regimen controls resistant disease in 9 of 10 cases: study – Reuters (free)
3 – Original Articles: Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection – New England Journal of Medicine (link to abstract – $ for full-text) AND Long-Acting Cabotegravir and Rilpivirine for Maintenance of HIV-1 Suppression – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Monthly Injections Noninferior to Daily Treatment for HIV – NEJM Journal Watch (free) AND A more convenient, monthly treatment for HIV cleared a key hurdle – ScienceNews (free)
4 – MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Adding MRI-targeted biopsy leads to more reliable diagnosis of aggressive prostate cancer – University of Maryland Medical Center (free) AND MRI-Targeted and Systematic Biopsy for Prostate Cancer Diagnosis – NEJM Journal Watch (free) AND Testing with combined biopsy method improves prostate cancer diagnosis in NIH study – NIH News Release (free)
Source: PSNet
Related: Review: Renal Replacement Therapy in the Critical Care Setting (free resources)
Commentaries: Bariatric Surgery and Diabetes Treatment—Finding the Sweet Spot – JAMA Surgery (free) AND Gastric bypass may be best weight-loss surgery for diabetes remission – Reuters (free) AND Gastric bypass improves weight loss, type 2 diabetes, study finds – UPI (free)
8 – Male and Female Physician Suicidality: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)
Editorial: Physician Suicide—A Personal and Community Tragedy (free for a limited period)
Commentary: Meta-Analysis Spotlights Challenge of Physician Suicide – Psychiatric New Alert (free)
Editorial: Egg consumption and cardiovascular disease (free)
Commentary: Study Finds No Link Between Moderate Egg Consumption and Overall Cvd Risk – MedicalResearch.com (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 5 March 2020 Edition
5 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Wed March 04 – 10 Stories of The Day!
4 Mar, 2020 | 10:24h | UTC
Algorithm: Proposed detailed management algorithm for health-care providers (free PDF)
See also: Latest developments and research in the COVID-19 outbreak (several resources)
2 – Low back and neck pain tops U.S. health spending – Institute for Health Metrics and Evaluation (free)
Original Study: US Health Care Spending by Payer and Health Condition, 1996-2016 – JAMA (free for a limited period)
3 – Association of QT-Prolonging Medications with Risk of Autopsy-Defined Causes of Sudden Death – JAMA Internal Medicine (free for a limited period)
Commentary: QT-Prolonging Medications and Sudden Death – American College of Cardiology (free)
4 – The Effect of Influenza Vaccination for the Elderly on Hospitalization and Mortality: An Observational Study With a Regression Discontinuity Design – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Flu vaccine may not decrease hospitalization or mortality among elderly persons – American College of Physicians (free) AND Expert reaction to study looking at the flu vaccine and hospitalisation and mortality in older people – Science Media Centre (free) AND Isolated flu vaccination of elderly may not decrease hospitalization or mortality rates – ACP Internist (free)
5 – Time‐Sensitive Interventions in Hospitalized Patients with Cirrhosis – Clinical Liver Disease (free)
7 – Melatonin shows potential for reducing delirium among older people after surgery – NIHR Signal (free)
Original Study: Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis – BMC Geriatrics (free)
8 – Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women with Dense Breasts Undergoing Screening – JAMA (free for a limited period)
Editorials: An Abbreviated MRI Protocol for Breast Cancer Screening in Women With Dense Breasts: Promising Results, but Further Evaluation Required Prior to Widespread Implementation – JAMA (free for a limited period) AND Options for Addressing the Dilemma of Managing Dense Breasts – JAMA Surgery (free for a limited period)
Commentary: Abbreviated Breast MRI vs Digital Breast Tomosynthesis Screening in Women With Dense Breasts – The ASCO Post (free)
Commentary: Eating a vegetarian diet rich in nuts, vegetables, soy linked to lower stroke risk – American Academy of Neurology (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 4 March 2020 Edition
4 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Tue March 03 – 10 Stories of The Day!
3 Mar, 2020 | 08:23h | UTC
Author Interview: USPSTF Recommendation: Screening for Hepatitis C Virus Infection in Adolescents and Adults (free audio)
Editorials: Universal Screening for Hepatitis C Virus Infection: A Step Toward Elimination – JAMA (free for a limited period) AND USPSTF’s Hepatitis C Screening Recommendation—A Necessary Step to Tackling an Evolving Epidemic – JAMA Network Open (free)
Evidence Report and Systematic Review: Screening for Hepatitis C Virus Infection in Adolescents and Adults – US Preventive Services Task Force (free)
JAMA Patient Page: Screening for Hepatitis C Virus Infection (free)
Commentary: Experts recommend testing U.S. adults ages 18-79 for hep C – Reuters (free)
3 – Current and future treatments for tuberculosis – The BMJ (free)
4 – People leave hospital after surgery sooner if hospitals follow ‘enhanced recovery protocols’ – NIHR Signal (free)
Original Study: Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review – Health Services and Delivery Research (free)
6 – Membrane sweeping for induction of labour – Cochrane Library (free)
Summary: Membrane sweeping for induction of labour – Cochrane Library (free)
7 – Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life – Cochrane Library (free)
Summary: Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life – Cochrane Library (free)
Commentaries: Digital health interventions for children with ADHD – The Lancet Digital Health (free) AND Video game-like intervention shows promise in improving attention of children with ADHD – The Lancet (free)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 3 March 2020 Edition
3 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Mon March 02 – 10 Stories of The Day!
2 Mar, 2020 | 00:45h | UTC
1 – Clinical Characteristics of Coronavirus Disease 2019 in China – New England Journal of Medicine (free)
Editorial: Covid-19 — Navigating the Uncharted – New England Journal of Medicine (free)
Related Commentaries: Responding to Covid-19 — A Once-in-a-Century Pandemic? – New England Journal of Medicine (free) AND Escaping Pandora’s Box — Another Novel Coronavirus – New England Journal of Medicine (free)
See also: Latest Developments in the COVID-19 Outbreak (several resources on the subject)
2 – COVID-19—New Insights on a Rapidly Changing Epidemic – JAMA (free)
See also: Latest Developments in the COVID-19 Outbreak (several resources on the subject)
Commentary: Extended-release drugs could be costing U.S. healthcare system billions – Reuters (free)
Related: Evidence Synthesis: Should Antidepressants be Used for Major Depressive Disorder? (free studies on the subject)
5 – Alex Nowbar’s journal reviews, 28 February 2020 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
7 – Adult Liver Transplantation: A UK Clinical Guideline
Part 1: pre-operation – Frontline Gastroenterology (free)
Part 2: surgery and post-operation – Frontline Gastroenterology (free)
8 – Infographic. Exercise for intermittent claudication – British Journal of Sports Medicine (free)
Commentary: Walking may be best treatment for pain from clogged leg arteries – Reuters (free)
9 – Essentials for Radiologists on COVID-19: An Update—Radiology Scientific Expert Panel – Radiology (free)
Related: COVID-19: Chest CT May be the Best Screening Tool for Diagnosis in Epidemic Areas (free studies on the subject) AND Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study – The Lancet Infectious Diseases (free) AND Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 – European Journal of Nuclear Medicine and Molecular Imaging (free PDF) AND Chest CT Findings in Patients with Corona Virus Disease 2019 and its Relationship with Clinical Features – Investigative Radiology (free PDF) AND 2019 Novel Coronavirus (COVID-19) Pneumonia: Serial Computed Tomography Findings – Korean Journal of Radiology (free PDF) AND Chest Radiographic and CT Findings of the 2019 Novel Coronavirus Disease (COVID-19): Analysis of Nine Patients Treated in Korea – Korean Journal of Radiology (free PDF)
See also: Latest Developments and Research in the COVID-19 Outbreak (several resources on the subject)
10 – Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 2 March 2020 Edition
2 March 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Fri February 28 – 10 Stories of The Day!
28 Feb, 2020 | 08:40h | UTC
Commentaries: Further evidence adds weight to call for urgent action on salt targets – George Institute for Global Health (free) AND Cutting salt likely to prevent future heart disease, even if you’re not at risk now – CNN (free)
2 – Model List of Essential Medicines – World Health Organization (free)
News Release: WHO launches a digital version of its Model list of Essential Medicines (EML) – World Health Organization (free)
Related: WHO Updates Global Guidance on Medicines and Diagnostic Tests (free resources)
3 – The Inevitable Reimagining of Medical Education – JAMA (free for a limited period)
Author Interview: The Inevitable Reimagining of Medical Education (free audio)
3 – When Can Intermediate Outcomes Be Used as Surrogate Outcomes? – JAMA (free for a limited period)
5 – SPIRIT extension and elaboration for n-of-1 trials: SPENT 2019 checklist – The BMJ (free for a limited period)
Related Opinion: Will Spring Temperatures Stop Coronavirus? – Forbes (free)
Commentary: HPV vaccination found to prevent more cases and deaths than previous estimates – London School of Hygiene & Tropical Medicine (free)
Related: Modeling Analysis: Mortality Impact of Achieving WHO Cervical Cancer Elimination Targets (free study and commentaries)
8 – A single-dose HPV vaccine would have a big impact on cancer prevention – STAT (free)
Related: Another Observational Study Suggests One Dose of HPV Vaccine may be Enough (free studies) AND Another Study Suggesting One Dose of HPV Vaccine may be Effective for Prevention of Cervical Cancer (link to abstract and commentaries)
9 – Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Higher Microbiota Diversity in Hematologic Cancer Treatment Could Lower Mortality Risk, Study Finds – AJMC (free) AND Gut Diversity Before HCT Predicts Survival in Blood Cancers – MedPage Today (free registration required)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 28 February 2020 Edition
28 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Thu February 27 – 10 Stories of The Day!
27 Feb, 2020 | 10:28h | UTC
1 – Impetigo: antimicrobial prescribing – National Institute for Health and Care Excellence (free)
Commentary: Antiseptic not antibiotic should be considered for impetigo – PharmaField (free)
Related: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
2 – Neonatal parenteral nutrition – National Institute for Health and Care Excellence (free)
Top Things to Know: Exercise-Related Acute Cardiovascular Events and Potential Deleterious Adaptations Following Long-Term Exercise Training – American Heart Association (free)
News Release: Slow, steady increase in exercise intensity is best for heart health — much more is not always much better – AHA Newsroom (free)
Commentaries: Exercise Health Benefits and Risks-In Search of the Perfect Balance – American Heart Association (free) AND Marathons, triathlons may not be best exercise for heart health – UPI (free)
4 – Getting your workplace ready for COVID-19 – World Health Organization (free PDF)
Related Guideline: COVID-19: guidance for employers and businesses – Public Health England (free)
“WHO just published guidance on how to prevent the spread of COVID- 19 in a workplace & protect your customers, contractors & employees. We advise these measures to be taken now, even if coronavirus hasn’t arrived in communities where you operate.” (via @DrTedros see Tweet)
Commentary: CT provides best diagnosis for COVID-19 – Radiological Society of North America (free)
Related Studies: Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR – Radiology (free) AND Coronavirus Outbreak: What the Department of Radiology Should Know – Journal of the American College of Radiology (free) AND Coronavirus Disease 2019 (COVID-19): A Perspective from China – Radiology (free) AND Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection – Radiology (free) AND Outbreak of novel coronavirus (COVID-19): What is the role of radiologists? – European Radiology (free) AND Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing – Radiology (free) AND Pre- and Posttreatment Chest CT Findings: 2019 Novel Coronavirus (2019-nCoV) Pneumonia – Radiology (free)
Related: Intensive care during the coronavirus epidemic – Intensive Care Medicine (free) AND How to face the novel coronavirus infection during the 2019–2020 epidemic: the experience of Sichuan Provincial People’s Hospital – Intensive Care Medicine (free) AND Critical care management of adults with community-acquired severe respiratory viral infection – Intensive Care Medicine (free) AND Coronavirus epidemic: preparing for extracorporeal organ support in intensive care – The Lancet Respiratory medicine (free) AND Preparing for the Most Critically Ill Patients With COVID-19: The Potential Role of Extracorporeal Membrane Oxygenation – JAMA (free)
7 – Metformin to reduce metabolic complications and inflammation in patients on systemic glucocorticoid therapy: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Metformin could mitigate glucocorticoid-related complications – Medicine Matters (free) AND Metabolic effects of glucocorticoids reversed with metformin – Healio (free registration required) AND Diabetes Drug May Benefit Long-Term Steroid Users – MedPage Today (free registration required)
8 – The Low-FODMAP Diet Helps IBS Symptoms, but Questions Remain – JAMA (free for a limited period)
Related: Low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet improves symptoms in adults suffering from irritable bowel syndrome (IBS) compared to standard IBS diet: A meta-analysis of clinical studies – PLOS One (free) AND The Low FODMAP Diet: Recent Advances in Understanding Its Mechanisms and Efficacy in IBS – Gut (free PDF)
Editorial: Sugar‐Sweetened Beverage Consumption and Lipid Profile: More Evidence for Interventions (free)
Commentaries: Sugary drinks a sour choice for adults trying to maintain normal cholesterol levels – Tufts University (free) AND Drinks with added sugars linked to lipid imbalance, which increases CVD risk – American Heart Association (free)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 27 February 2020 Edition
27 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Wed February 26 – 10 Stories of The Day!
26 Feb, 2020 | 10:46h | UTC
1 – Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology (free link via Google Scholar)
Summary: Updated Polypectomy Surveillance Recommendations – NEJM Journal Watch (free)
Related: British Society of Gastroenterology/Association of Coloproctology of Great Britain and Ireland/Public Health England post-polypectomy and post-colorectal cancer resection surveillance guidelines – Gut (free guidelines and studies on the subject)
Evidence Report: Screening for Cognitive Impairment in Older Adults – US Preventive Services Task Force/JAMA (free)
Editorials: Issues and Questions Surrounding Screening for Cognitive Impairment in Older Patients – JAMA (free for a limited period) AND Evidence Still Lacking for Recommendation of Screening for Cognitive Impairment in Older Adults – JAMA Internal Medicine (free for a limited period)
Author Interview: USPSTF Recommendation: Screening for Cognitive Impairment (free audio)
JAMA Patient Page: Screening for Cognitive Impairment in Older Adults (free)
Commentary: U.S. Medical Panel Thinks Twice About Pushing Cognitive Screening For Dementia – Kaiser Health News (free)
3 – European Position Paper on Rhinosinusitis and Nasal Polyps 2020 – Rhinology (free PDF)
4 – Former CDC director: A coronavirus pandemic is inevitable. What now? – CNN (free)
5 – Preoperative Cardiac Risk Assessment – Mayo Clinic Proceedings (free)
Related guidelines: Preoperative evaluation of adult patients before elective, noncardiothoracic surgery – Der Anaesthesist (free) AND 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery (free) AND 2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management (free) AND Routine preoperative tests for elective surgery – NICE Guideline (free) AND Canadian Cardiovascular Society Guidelines on Perioperative Cardiac Risk Assessment and Management for Patients Who Undergo Noncardiac Surgery (free) AND 3rd Guideline for Perioperative Cardiovascular Evaluation of the Brazilian Society of Cardiology (free)
6 – Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Dialysis – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Anticoagulation for Dialysis Patients with Atrial Fibrillation: No Benefit Seen – NEJM Journal Watch (free for a limited period)
7 – Incidence of Tetanus and Diphtheria in Relation to Adult Vaccination Schedules – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentaries: Adults don’t need tetanus, diphtheria boosters if fully vaccinated as children – Oregon Health & Science University (free) AND Most adults don’t need booster vaccinations for tetanus and diphtheria, new study concludes – STAT (free)
8 – In praise of replication studies and null results – Nature (free)
Related: Editorial – “No Raw Data, No Science: Another Possible Source of the Reproducibility Crisis” (studies and commentaries on the subject)
“More funders and publishers must support such work and emphasize its value to the research community.”
9 – Milk and Juice Are Not as Needed as You Might Think – The New York Times (10 articles per month are free)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 26 February 2020 Edition
26 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Tue February 25 – 10 Stories of The Day!
25 Feb, 2020 | 06:52h | UTC
1 – Physical Activity Assessment and Counseling in Pediatric Clinical Settings – Pediatrics (free)
News Releases: New report guides physical activity counseling in pediatric clinical settings – AAP News (free) AND American Academy of Pediatrics Urges Physical Activity Prescriptions at Doctor Visits – American Academy of Pediatrics (free)
2 – EASL Clinical Practice Guideline: Occupational liver diseases – Journal of Hepatology (free)
Commentary: Study of 72,000 COVID-19 patients finds 2.3% death rate – CIDRAP (free)
5 – Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Antihypertensive Prescribing Cascades as High-Priority Targets for Deprescribing – JAMA Internal Medicine (free for a limited period)
Author Interview: Evaluation of Association Between Gastric Acid Suppression and Risk of Intestinal Colonization With MDROs – JAMA (free)
Commentary: Deprescribing Proton Pump Inhibitors: Overcoming Resistance – JAMA Internal Medicine (free for a limited period)
Related: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing Proton Pump Inhibitors – Therapeutics Initiative (free)
7 – Continuation of Annual Screening Mammography and Breast Cancer Mortality in Women Older Than 70 Years – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Mammography may not benefit healthy women older than age 75 – ACP Internist (free) AND Mammography in Women Older Than 75 Does Not Confer an Additional Survival Benefit – AJMC (free)
8 – Pharmacologic Therapies in Patients With Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review With Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Meta-Analysis: Systemic Corticosteroids, Antibiotics Effective for COPD Exacerbations – NEJM Journal Watch (free)
9 – The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries – European Heart Journal (free for a limited period)
Commentaries: Study of 418,000 Europeans finds different foods linked to different types of stroke – European Society of Cardiology (free) AND Expert reaction to study looking at foods and stroke risk – Science Media Centre (free)
10 – Is COVID-19 Going Pandemic? / Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 25 February 2020 Edition
25 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)