Vascular Surgery

Leg ulcer infection: antimicrobial prescribing – National Institute for Health and Care Excellence (free)

Related: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)


Related Commentary on Twitter


Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial – The Lancet (free)

Invited Commentary: Angiotensin-II receptor blockade in Marfan syndrome – The Lancet (free)


Related Commentary on Twitter


Supplement: Vascular Imaging

16 Oct, 2019 | 08:42h | UTC

Medical Management vs Mechanical Thrombectomy for Mild Strokes: An International Multicenter Study and Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)

Commentaries: Medical Therapy Vs Endovascular Therapy: Similar Outcomes for Mild Strokes – Neurology Today (free) AND Similar Benefits for Thrombectomy, Medical Management, in Mild Stroke – Medscape (free)


Related Commentary on Twitter


Inguinal Vascular Surgical Wound Protection by Incisional Negative Pressure Wound Therapy: A Randomized Controlled Trial—INVIPS Trial – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts


Related Commentary on Twitter


A Multicenter Trial of Vena Cava Filters in Severely Injured Patients – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Liberal IVC Filter Use Not Warranted in Severe Trauma Patients – TCTMD (free)


Related Commentary on Twitter


Cardiovascular Risk Factors Associated with Venous Thromboembolism – JAMA Cardiology (free)

“Older age, smoking, and adiposity were consistently associated with higher VTE risk.”


When Is the Surgeon Too Old to Operate? – The New York Times (free)

Related: Perspective: Assessing the Performance of Aging Surgeons (free for a limited period) AND Observational Study: Age and Sex of Surgeons and Mortality of Older Surgical Patients (free study and commentary) AND The Elderly and Driving: When Is It Time to Hit the Brakes? – The New York Times (10 articles per month are free)


Related Commentary on Twitter

Patient-reported complications related to peripherally inserted central catheters: a multicentre prospective cohort study – BMJ Quality & Safety (free)


Related Commentary on Twitter


Review: Intracranial Aneurysms

18 Nov, 2018 | 00:14h | UTC

Association of Blood Pressure Measurements With Peripheral Artery Disease Events: Reanalysis of the ALLHAT Data – Circulation (free)

Editorial: New Curveball for Hypertension Guidelines? Blood Pressure Targets in Peripheral Artery Disease (free)

“we found a higher rate of lower extremity PAD events with higher and lower SBP and pulse pressure and with lower DBP.”


Residual vein occlusion in relation to immediate compression and postthrombotic syndrome in deep vein thrombosis – Blood (free PDF)

Commentary: Immediate compression could help prevent complications after deep-vein thrombosis – American Society of Hematology (free)

“Study supports use of this simple, low-cost intervention even for patients without symptoms” (from American Society of Hematology)


Association of Inferior Vena Cava Filter Placement for Venous Thromboembolic Disease and a Contraindication to Anticoagulation With 30-Day Mortality – JAMA Network Open (free)

Commentaries: Inferior Vena Cava Filters and Mortality: Is It the Underlying Process, the Patient, or the Device? (free)

“Could IVC filters be causing harm? They began being used before @US_FDA started approving devices. This article raises possibility of increased mortality. Maybe where we need trials to determine safety and effectiveness”. (via @hmkyale see Tweet)


Supplement: Advanced Aortic Imaging and Intervention – Cardiovascular Diagnosis and Therapy (free articles)

Series of review articles on the topic.


Review: The Vasculature in Prediabetes

24 Apr, 2018 | 17:59h | UTC

Review: Pelvic Vein Incompetence

10 Jan, 2018 | 00:08h | UTC

Review: Carotid Artery Stenting

5 Dec, 2017 | 18:10h | UTC

Low dose aspirin as adjuvant treatment for venous leg ulceration: pragmatic, randomised, double blind, placebo controlled trial (Aspirin4VLU) – The BMJ (free)

“Low dose aspirin does not increase time to healing of venous leg ulcers, percentage healed, estimated change in venous leg ulcer area, or change in health related quality of life”.


Review: Diabetic foot

20 Nov, 2017 | 18:01h | UTC

Acute mesenteric ischemia: guidelines

9 Aug, 2017 | 16:57h | UTC

Interventions for the prevention of recurrent erysipelas and cellulitis – Cochrane Library (link to summary – $ for full-text)

Commentary: Ongoing Antibiotic Prophylaxis Helps Prevent Cellulitis Recurrence – Medscape (free registration required)


Randomized clinical trial of comprehensive geriatric assessment and optimization in vascular surgery – British Journal of Surgery (link to abstract – $ for full-text)

Source: ACP Journal Club ($ resource to find articles of interest)

In this RCT, a comprehensive preoperative geriatric assessment and optimization before vascular surgery was associated with shorter length of hospital stay, lower incidence of complications, and patients were less likely to be discharged to a higher level of dependency.


A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts (free resource to find articles of interest)

“Antiplatelet therapy at the time of noncardiac surgery confers minimal bleeding risk with no difference in thrombotic complications. In many cases, it is safe to continue antiplatelet therapy in patients with important indications for their use”


Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Growth, rupture risk appear low for small intracranial aneurysms, review indicates – ACP Internist Weekly (free) AND How Frequently Do Small Brain Aneurysms Rupture? – MedPage Today (free registration required)

“The annualized rupture rate was 0% for aneurysms 3 mm or smaller, below 0.5% for aneurysms 5 mm or smaller, and below 1% for aneurysms 7 mm or smaller”


Carotid Artery Stenting Versus Endarterectomy for Stroke Prevention: A Meta-Analysis of Clinical Trials – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: CAS vs. CEA for Stroke Prevention – American College of Cardiology, Latest in Cardiology (free)

“CAS and CEA were associated with similar rates of a composite of periprocedural death, stroke, MI, or nonperiprocedural ipsilateral stroke. The risk of long-term overall stroke was significantly higher with CAS, and was mostly attributed to periprocedural minor stroke”.


Thrombolysis may reduce complications of deep vein thrombosis – NIHR Signal (free)

Original article: Thrombolysis for acute deep vein thrombosis – Cochrane Library (Link to abstract – $ for full-text)

Thrombolysis reduced post-thrombotic syndrome, but lead to more bleeding complications than standard anticoagulation. “Individuals with clots in the pelvis and thigh, which carry higher risk of complications, may be likely to gain most benefit”.