TOP 10 Medical News Stories
Mon February 24 – 10 Stories of The Day!
24 Feb, 2020 | 00:37h | UTC
Commentary: New evidence-based clinical guidelines for surgical treatment of thyroid disease – News Medical (free)
2 – Preventing Surgical Site Infections: Looking Beyond the Current Guidelines – JAMA (free for a limited period)
Related Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) AND Global guidelines on the prevention of surgical site infection – World Health Organization (free) AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free) AND APSIC guidelines for the prevention of surgical site infections – Antimicrobial Resistance & Infection Control (free) AND Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines – World Journal of Emergency Surgery (free)
4 – Opinion: Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now” – Virology Down Under (free)
Related commentaries: Covid-19 now a pandemic, say global experts – RTHK (free) AND Covid-19 is now a pandemic, says Leuven specialist – The Brussels Times (free) AND “We are at a turning point”: The coronavirus outbreak is looking more like a pandemic – Vox (free) AND Understanding pandemics: What they mean, don’t mean, and what comes next with the coronavirus – STAT (free)
Note: As with every article on this website, this is not necessarily an endorsement.
Commentaries: Screen for Cervical Cancer Every 3 Years: More Is a ‘Waste’ – Medscape (free registration required)
Related Guideline: USPSTF Statement: Screening for Cervical Cancer (free resources)
7 – No raw data, no science: another possible source of the reproducibility crisis – Molecular Brain (free)
Commentary: How a ‘no raw data, no science’ outlook can resolve the reproducibility crisis in science – by Fujita Health University (free)
Related: Can We Science Our Way out of the Reproducibility Crisis? – Absolutely Maybe Blog (free) AND Study: Evaluating the Replicability of Social Science Experiments (link to abstract and commentaries) AND Five ways to fix statistics – Nature (free) AND Make replication studies ‘a normal and essential part of science,’ Dutch science academy says – Science (free) AND Reproducibility of clinical research in critical care: a scoping review (free) AND Reproducibility Trial Publishes Two Conclusions for One Paper (free)
Editorial: Natural enemy or friend? Pneumonia in the very elderly critically ill patient (free)
Related Guidelines: Prevention of Drowning – American Academy of Pediatrics (free) AND Preventing drowning: an implementation guide – World Health Organization (free PDF) AND Global report on drowning: preventing a leading killer – World Health Organization (free PDF) Report: Open Water Drowning and Risks for Children (free) AND Wilderness Medical Society Clinical Practice Guidelines for the Treatment and Prevention of Drowning: 2019 Update – Wilderness and Environmental Medicine (free)
10 – Is COVID-19 Going Pandemic? / Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 24 February 2020 Edition
24 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Fri February 21 – 10 Stories of The Day!
21 Feb, 2020 | 10:56h | UTC
1 – Bright Futures Guidelines and Pocket Guide (free resources)
News Releases: 2020 Recommendations for Preventive Pediatric Health Care – Pediatrics (free) AND Periodicity Schedule: Recommendations from the American Academy of Pediatrics for screenings and assessments at each well-child visit from infancy through adolescence (free)
4 – Individual Differences in Response to Antidepressants: A Meta-analysis of Placebo-Controlled Randomized Clinical Trials – JAMA Psychiatry (free for a limited period)
Editorial: Is This Where We Stand After Decades of Research to Develop More Personalized Treatments for Depression? (free for a limited period)
Commentary: How Variable are Patient Responses to Antidepressants? – MedPage Today (free registration required)
5 – Yield, Efficiency and Costs of Mass Screening Algorithms for Tuberculosis in Brazilian Prisons – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentary: Mass TB screening with point-of-care test is cost-effective, Brazil prison study shows – Science Speaks: Global ID News (free)
6 – How Common Mental Shortcuts Can Cause Major Physician Errors – The New York Times (10 articles per month are free)
Related Study: Behavioral Heuristics in Coronary-Artery Bypass Graft Surgery – New England Journal of Medicine ($)
Related Study: Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Emollients for prevention of atopic dermatitis in infancy – The Lancet (free) AND Daily moisturizer does not prevent eczema according to new research – News Medical (free)
8 – Contact isolation versus standard precautions to decrease acquisition of extended-spectrum β-lactamase-producing Enterobacterales in non-critical care wards: a cluster-randomised crossover trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
9 – A Deep Learning Approach to Antibiotic Discovery – Cell (free for a limited period)
Commentaries: Powerful antibiotics discovered using AI – Nature (free) AND Aided by machine learning, scientists find a novel antibiotic able to kill superbugs in mice – STAT (free)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 20 February 2020 Edition
20 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Thu February 20 – 10 Stories of The Day!
20 Feb, 2020 | 11:04h | UTC
Commentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)
Commentaries: Warning over prescribing antibiotics during pregnancy – OnMedica (free) AND Some antibiotics prescribed during pregnancy linked with birth defects – BMJ (free) AND Expert reaction to study looking at macrolide antibiotics in pregnancy and birth defects – Science Media Centre (free) AND Macrolide Antibiotics Early in Pregnancy Tied to Birth Defects – The New York Times (10 articles per month are free)
3 – Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Author Interview: Quality of Life and Patient Satisfaction After Antibiotic Therapy vs Appendectomy (free audio)
Commentaries: Quality of Life—The Appendix – JAMA Surgery (free) AND Patient satisfaction and quality of life similar across all appendicitis treatments – News Medical (free)
Related: Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children (several studies on the subject) AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International (free)
Related Opinion: To maximize progress in global health, invest more in community health workers – STAT (free)
Video Summary: Vitamin E Acetate Associated with EVALI (free)
Related Report: Syndromic Surveillance for E-Cigarette, or Vaping, Product Use–Associated Lung Injury – new England Journal of Medicine (free)
See also: The EVALI and Youth Vaping Epidemics — Implications for Public Health – New England Journal of Medicine (free) AND CDC: Vaping Lung Illness Probably Caused by Vitamin E Acetate (free resources)
6 – Alex Nowbar’s journal reviews, 20 February 2020 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
7 – Clinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Commentary: Clinical Pre-test Prob vs. Age-adjusted D-dimer for DVT – The Meta Analysis – JournalFeed (free)
Related Studies: Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract and commentary) AND Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study – JAMA (free)
8 – Pre-Hospital Administration of Epinephrine in Pediatric Patients With Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Epinephrine for Pediatric OHCA Mirrors PARAMEDIC2 – JournalFeed (free) AND Getting to the heart of epinephrine use in pediatric cardiac arrest patients – Osaka University (free)
Related Study: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (free study and commentaries)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 20 February 2020 Edition
20 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Wed February 19 – 10 Stories of The Day!
19 Feb, 2020 | 10:42h | UTC
1 – Homepage: A future for the world’s children? A WHO-UNICEF-Lancet Commission – The Lancet (free articles)
Commission: A future for the world’s children? A WHO–UNICEF–Lancet Commission (free)
Editorial: No excuses and no time to lose (free)
Invited Commentaries: The voices of children in the global health debate (free) AND Framing an agenda for children thriving in the SDG era: a WHO–UNICEF–Lancet Commission on Child Health and Wellbeing (free)
WHO News Release: A Future for the World’s Children – World Health Organization (free)
Commentaries: Children facing uncertain future, experts warn – BBC (free) AND The world is failing to ensure children have a ‘liveable planet’, report finds – The Guardian (free)
2 – The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) – China, 2020 – China CDC Weekly (free PDF – link via Forbes)
Commentaries: Coronavirus: Largest study suggests elderly and sick are most at risk – BBC (free) AND New Chinese Study Finds That The Elderly Are Most At Risk From The Coronavirus [Infographic] – Forbes (free) AND Expert reaction to WHO Director General’s statement on new paper from China detailing over 44,000 of their cases – Science Media Centre (free)
Editorial: The ISCHEMIA Trial Meets the Rashomon Effect: Lessons for Clinical Practice (free for a limited period)
4 – Predictive Accuracy of a Polygenic Risk Score Compared with a Clinical Risk Score for Incident Coronary Heart Disease – JAMA (free for a limited period)
Related Study: Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease – JAMA (free for a limited period)
Editorial: Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease? (free)
Commentary: Gene tests for heart disease risk have limited benefit – Imperial College London (free)
Commentary: Insufficient evidence backing herbal medicines for weight loss – University of Sidney (free)
Commentary: Sugary Drink Consumption Plunges in Chile After New Food Law – The New York Times (10 articles per month are free)
Original WHO Statement: WHO’s List of Urgent Global Health Challenges for the New Decade (free statement and commentary)
9 – Antimicrobial stewardship failure: time for a new model – Journal of Antimicrobial Chemotherapy (free)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 19 February 2020 Edition
19 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Tue February 18 – 10 Stories of The Day!
18 Feb, 2020 | 10:44h | UTC
Commentary: New VA/DoD guidelines address sleep-related issues in military personnel, veterans – University of Texas Health Science Center at San Antonio (free)
2 – Effect of salt substitution on community-wide blood pressure and hypertension incidence – Nature Medicine (free for a limited period)
Commentaries Before Publication at #ESCCongress: Community-based salt substitution programme lowers blood pressure – European Society of Cardiology (free) AND Community-Level Salt-Swapping Strategy Pays Dividends in Peru – TCTMD (free)
3 – Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: No Sedation: An Option in Mechanically Ventilated ICU Patients – MedPage Today (free registration required)
4 – #195 TWDFNR 3: Potassium, Oxygen, and Antipsychotics – The Curbsiders Internal Medicine Podcast (free)
Related Podcasts: #109: Things We Do For No Reason: A High Value Episode (free) AND #165 Things We Do For No Reason™ Part 2 (free)
See also: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine (free articles)
Related: ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated” (free statement and commentary) AND Another Study Questions the Association of Contrast Use and Acute Kidney Injury (studies on the subject)
6 – Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Hypertension Treatments with Chlorthalidone vs HCTZ: Cardiac and Safety Outcomes – MedicalResearch.com (free)
7 – Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia – JAMA Internal Medicine (free for a limited period)
Editorial: Overuse of Broad-Spectrum Antibiotics for Pneumonia (free for a limited period)
8 – Intermittent fasting and weight loss: Systematic review – Canadian Family Physician (free)
Related: The Benefits of Intermittent Fasting – The New York Times (10 articles per month are free) AND Podcast – Intermittent fasting – NEJM Journal Watch (free audio) AND Effects of Intermittent Fasting on Health, Aging, and Disease – New England Journal of Medicine ($)
9 – Cannabis use during pregnancy and postpartum – Canadian Family Physician (free)
Related: AAP Clinical Report: Implications of Marijuana Use During Pregnancy and Breastfeeding (free report and commentaries)
“There is no known safe level of cannabis use during pregnancy or lactation”
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 18 February 2020 Edition
18 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Mon February 17 – 10 Stories of The Day!
16 Feb, 2020 | 21:46h | UTC
News Release: New guidelines for hepatic failure in the intensive care unit – Wolters Kluwer Health (free)
See also: Executive Summary (free)
See also: Mitral Regurgitation Management Focused Update: Key Points – American College of Cardiology (free)
3 – A Randomized Controlled Trial of Ceftriaxone and Doxycycline, with or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease – Clinical Infectious Diseases (link to abstract – $ for full-text)
News Release: Chronic kidney disease a ‘global killer in plain sight’ – Institute for Health Metrics and Evaluation (free)
Commentaries: The global burden of chronic kidney disease – The Lancet (free) AND Chronic kidney disease killing millions worldwide – News Medical (free) AND Chronic kidney disease kills more than 1M people annually worldwide – UPI (free)
5 – 65 Trial – The Bottom Line (free) AND The 65 trial: Is 60 the new 65? – PulmCrit (free)
Original Study: Randomized Trial: Comparison of Different Blood Pressure Targets for Vasopressor Therapy in Older Critically Ill Patients with Vasodilatory Hypotension – JAMA (free)
6 – Alex Nowbar’s weekly journal review, 14 February 2020 – The BMJ Opinion (free)
“Alex Nowbar reviews the latest research from the top medical journals.”
Source: Lorcaserin (Belviq ) Withdrawn From US Market Due to Cancer Risk – Medscape (free registration required)
Related: FDA Safety Communication: Possible Increased Risk of Cancer with Weight-loss Medicine Lorcaserin (free)
8 – Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis – The American Journal of Gastroenterology (link to abstract – $ for full-text)
Commentary: Fecal Occult Blood Tests Should Not Be Used for Diagnostic Indications – NEJM Journal Watch (free for a limited period)
9 – An electroencephalographic signature predicts antidepressant response in major depression – Nature Biotechnology (link to abstract – $ for full-text)
Commentaries: Neural signature identifies people likely to respond to antidepressant medication – NIH News Releases (free) AND Brain-wave pattern can identify people likely to respond to antidepressant, study finds – Stanford Medicine (free) AND AI, brain scans may alter how doctors treat depression – UT Southwestern Medical Center (free) AND Brain scans could be used to identify who will benefit from antidepressants – Business Insider (free) AND Resting-State EEG Can Predict Sertraline Treatment Outcomes – MPR (free) AND Will That Antidepressant Work For You? The Answer May Lie In Your Brain Waves – NPR (free)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 17 February 2020 Edition
17 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Fri February 14 – 10 Stories of The Day!
14 Feb, 2020 | 10:56h | UTC
Related: WHO Guideline: Latent TB Infection (free) AND Study: Rifampicin is Likely to be the Safest Latent Tuberculosis Infection Treatment Option (free)
Commentary: Guidelines Updated on Treating Latent TB – NEJM Journal Watch (free)
Related: Physical Activity Guidelines for Americans (free resources)
4 – Management of acute ischemic stroke – The BMJ (free for a limited period)
5 – Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary: Hip fracture: accelerated surgery fails to cut mortality or major complications in HIP ATTACK trial – Univadis (free registration required)
Commentary: More evidence links ozone pollution to premature death – Reuters (free)
7 – The Climate Crisis and Clinical Practice – New England Journal of Medicine (free)
8 – Management of Acute Asthma in Adults in 2020 – JAMA (free for a limited period)
Related Article: Outpatient Management of Chronic Asthma in 2020 – JAMA (free for a limited period)
Editorial: New Therapeutic Strategies for Asthma – JAMA (free for a limited period)
9 – Efficacy, Safety, and Acceptability of Pharmacologic Treatments for Pediatric Migraine Prophylaxis: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (free for a limited period)
Editorial: Can We Really Stop Pediatric Migraine? Using Network Meta-analysis to Remove the Guess Work (free)
Commentary: Network Meta-Analysis: Scant Evidence That Migraine-Prevention Meds Work in Kids – NEJM Journal Watch (free)
10 – 14 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Thu February 13 – 10 Stories of The Day!
13 Feb, 2020 | 08:13h | UTC
1 – Recommended Childhood and Adolescent Immunization Schedule: United States, 2020 – Pediatrics (free)
Table 3. Recommended Child and Adolescent Immunization Schedule by Medical Indication, United States, 2020 – Centers for Disease Control and Prevention (free)
Related: Guidelines for the Prevention of Surgical Site Infections (free guidelines on the subject)
See also: Wilderness Medical Society Full List of Updated Clinical Practice Guidelines (free articles
4 – Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Choosing the Best Blood Pressure Target for Vasopressor Therapy (free for a limited period)
Conference Presentation: Effect of Reduced Vasopressor Exposure on Mortality in Older Critically Ill Patients With Vasodilatory Hypotension (free)
5 – Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound Dressing on Deep Surgical Site Infection After Surgery for Lower Limb Fractures Associated With Major Trauma: The WHIST Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Incisional Negative Pressure Wound Therapy Following Surgical Repair of Lower Extremity Fractures (free)
Commentary: Expensive new wound treatment method no more effective than cheap standard dressings – University of Warwick (free)
6 – Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Plasma Exchange and Glucocorticoids for ANCA-Associated Vasculitis (free)
Commentary: PEXIVAS: No benefit of plasma exchange in ANCA-associated vasculitis – Medicine Matters (free)
7 – Water for preventing urinary stones – Cochrane Library (free)
Summary: Increased water intake for preventing urinary stones – Cochrane Library (free)
Related: Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank: A Population-based Prospective Cohort Study – European Urology Focus (free) AND Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians (free)
Editorial: The poor performance of apps assessing skin cancer risk (free)
Commentaries: Skin cancer diagnosis apps are unreliable and poorly regulated, study shows – eCancer News (free) AND Phone apps unreliable for detecting all cases of skin cancer – OnMedica (free)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 13 February 2020 Edition
13 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Wed February 12 – 10 Stories of The Day!
12 Feb, 2020 | 10:21h | UTC
1 – COVID-19: WHO Names Disease Caused by the Novel Coronavirus / SARS-CoV-2: New Designation of the Virus Itself / + Latest Articles, News & Perspectives – 12 February 2020 Edition
World Health Organization COVID-19 Situation Report:
COVID-19: WHO Names Disease Caused by the Novel Coronavirus:
- WHO Director-General’s remarks at the media briefing on 2019-nCoV on 11 February 2020 – World Health Organization (free)
- Commentaries: Disease caused by the novel coronavirus officially has a name: Covid-19 – STAT (free) AND Coronavirus disease named Covid-19 – BBC (free) AND New Coronavirus Disease Officially Named COVID-19 By The World Health Organization – NPR (free) AND What’s in a Name? Why WHO’s Formal Name for the New Coronavirus Disease Matters – TIME (free)
“…we had to find a name that did not refer to a geographical location, an animal, an individual or group of people, and which is also pronounceable and related to the disease. Having a name matters to prevent the use of other names that can be inaccurate or stigmatizing. It also gives us a standard format to use for any future coronavirus outbreaks.”
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2): International Committee on Taxonomy of Viruses Designates the Virus Itself:
“It’s official: severe acute respiratory syndrome coronavirus 2 (#SARSCoV2) causes coronavirus disease 2019 (#COVID19)” (via @TheLancetInfDis see Tweet)
Latest Articles:
- Viewpoint: Preparation for Possible Sustained Transmission of 2019 Novel Coronavirus: Lessons From Previous Epidemics – JAMA (free)
- Correspondence: On the use of corticosteroids for 2019-nCoV pneumonia – The Lancet (free)
- Special Collection: Coronavirus (2019-nCoV): evidence relevant to critical care – Cochrane Library (free articles)
- Emerging novel Coronavirus (2019-nCoV) – Current scenario, evolutionary perspective based on genome analysis and recent developments – Veterinary Quaterly (free)
Selected News & Perspectives:
- New Coronavirus Has A Name – COVID-19; But As WHO Convenes Global Research Forum Many Other Unknowns Remain – Health Policy Watch (free)
- The Best Defense Against Disturbing New Diseases – The Atlantic (free)
- Deaths from newly named coronavirus disease top 1,000 – CIDRAP (free)
- At least 500 Wuhan medical staff infected with coronavirus – South China Morning Post (free)
- The coronavirus cruise ship quarantine is a scary public health experiment – VOX (free)
- 2,000 People Are Stranded on a U.S. Cruise Ship After 4 Countries Reject Entry Over Coronavirus Fears – TIME (free)
- The First Signs Are Emerging That China’s Coronavirus Containment Could Be Working – TIME (free)
- Coronavirus Researchers Are Using High-Tech Methods to Predict Where the Virus Might Go Next – TIME (free)
- Hospitals, governments need more data to prepare for the new coronavirus outbreak – STAT (free)
- Factbox: Latest on coronavirus spreading in China and beyond – Reuters (free)
- Exclusive: Coronavirus outbreak may be over in China by April – expert – Reuters (free)
- Coronavirus may be over soon in China, expert says, as WHO warns of global threat – Reuters (free)
- Coronavirus emergency ‘holds a very grave threat’ for world: WHO – Reuters (free)
- WHO brands coronavirus ‘public enemy number one’ – Reuters (free)
- Coronavirus ‘could infect 60% of global population if unchecked’ – The Guardian (free)
- Coronavirus should be seen as ‘public enemy number one’, says WHO – The Guardian (free)
- China launches coronavirus ‘close contact detector’ app – BBC (free)
- Australian scientists grow live coronavirus virus – News Medical (free)
- How AI Is Tracking the Coronavirus Outbreak – Wired (free)
- Cruise ship coronavirus infections double, exceeding the total for any country but China – The Washington Post (free)
- There’s No Specific Drug That Kills Coronavirus. But Doctors Have Ways To Treat It – Reuters (free)
Related: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
News Release: New report: a roadmap to improve virtual care in Canada – Canadian Medical Association (free)
4 – Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Combination Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: Not Ready for Prime Time (free for a limited period)
Commentaries: Trial pours cold water on combo treatment for MRSA bacteremia – CIDRAP (free) AND Trial shows using two drugs not better than one when treating MRSA blood infections – University of Melbourne (free)
5 – Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock – JAMA (free for a limited period)
Editorial: Microaxial Left Ventricular Assist Devices: In Search of an Appropriate Indication (free for a limited period)
Commentary: High-tech pump may increase risk of death and bleeding, study finds – Yale News (free)
6 – Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Related: Meta-Analysis: Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients with Moderate to Severe Acute Respiratory Distress Syndrome (free resources on the subject)
7 – Scrutinizing the effects of digital technology on mental health – Nature (free)
8 – Diet and Kidney Function: a Literature Review – Current Hypertension Report (free)
9 – Diagnosis and Treatment of Parkinson Disease: A Review – JAMA (free for a limited period)
Related Clinical Review Audio: Parkinson Disease (free)
Editorial: Palliative Programs for Persons With Parkinsonism—The Next Frontier (free for a limited period)
Commentaries: Palliative Care Improves Quality of Life, Symptom Burden of Patients With Parkinson Disease – AJMC (free) AND Palliative care could benefit people with Parkinson’s – OnMedica (free)
Tue February 11 – 10 Stories of The Day!
11 Feb, 2020 | 02:55h | UTC
1 – Noncommunicable Diseases Progress Monitor 2020 – World Health Organization (free PDF)
Related Publications: Tackling NCDs: “Best buys” and other recommended interventions for the prevention and control of noncommunicable diseases – World Health Organization (free PDF) AND Bridging the Gap on NCDs: From global promises to local progress – Policy brief – NCD Alliance (free PDF)
Commentary: Countries Falling Behind In Meeting Noncommunicable Disease Control Targets – Health Policy Watch (free)
Commentary: Researchers recommend early walking in a brace for Achilles tendon rupture – University of Warwick (free)
5 – Editor’s Note: A Successful but Underused Strategy for Reducing Low-Value Care: Stop Paying for It – JAMA Internal Medicine (free for a limited period)
Original Study: Comparison of Payment Changes and Choosing Wisely Recommendations for Use of Low-Value Laboratory Tests in the United States and Canada – JAMA Internal Medicine (free for a limited period)
Commentaries: Dialysis Modalities Found to Offer Similar Survival – Renal & Urology News (free) AND UL study reveals ‘identical’ survival for kidney dialysis patients using different treatments – University of Limerick (free)
7 – Alex Nowbar’s weekly journal review, 7 February 2020 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
See also: Episode List
9 – Intermittent fasting – NEJM Journal Watch (free audio)
“Intermittent fasting has salutary effects. Listen how Dr. Mark P. Mattson, co-author of a recent NEJM review on the topic, assesses the practice — and how he’s managed to skip breakfast for the past 30 years or so.”
For those interested in the subject, we suggest the reading of the recent review by Dr. Mark P. Mattson: Effects of Intermittent Fasting on Health, Aging, and Disease – New England Journal of Medicine ($)
10 – Novel Coronavirus (2019-nCoV) Latest Articles, Guidelines, News & Perspectives / 11 February 2020 Edition
See also: WHO: Novel Coronavirus (2019-nCoV) Situation Report – 10 February 2020 (free PDF)
Top Articles / Articles in High Impact Journals:
- Report 4: Severity of 2019-novel coronavirus (nCoV) – Imperial College London (free PDF) AND Summary: Severity of 2019-novel coronavirus (nCoV) (free) Commentary: Expert reaction to report on the severity of the novel coronavirus, as posted on the MRC Centre for Global Infectious Disease Analysis website – Science Media Centre (free)
- Critical care management of adults with community-acquired severe respiratory viral infection – Intensive Care Medicine (free)
- Persistence of coronaviruses on inanimate surfaces and its inactivation with biocidal agents – The Journal of Hospital Infection (free) AND Commentaries: How long coronaviruses persist on surfaces and how to inactivate them – Ruhr-Universität Bochum (free) AND Scientists Predict Coronavirus May Live For Up To Nine Days On Surfaces – Forbes (free)
- Therapeutic options for the 2019 novel coronavirus (2019-nCoV) – Nature Reviews Drug Discovery (free)
- The Rate of Underascertainment of Novel Coronavirus (2019-nCoV) Infection: Estimation Using Japanese Passengers Data on Evacuation Flights – Journal of Clinical Medicine (free PDF)
- Hand‐Hygiene Mitigation Strategies Against Global Disease Spreading through the Air Transportation Network – Risk Analysis (free) AND Commentary: To slow an epidemic, focus on handwashing – Massachusetts Institute of Technology (free)
Other Articles:
- Mission impossible? WHO director fights to prevent a pandemic without offending China – Science (free)
- What next for the coronavirus response? – The Lancet (free)
- What to do next to control the 2019-nCoV epidemic? – The Lancet (free)
- 2019-nCoV transmission through the ocular surface must not be ignored – The Lancet (free)
- 2019-nCoV epidemic: what about pregnancies? – The Lancet (free)
- Coronavirus epidemic: preparing for extracorporeal organ support in intensive care – The Lancet Respiratory medicine (free)
- Coronavirus: global stocks of protective gear are depleted, with demand at “100 times” normal level, WHO warns – The BMJ (free)
- In Beijing, coronavirus 2019-nCoV has created a siege mentality – The BMJ (free)
- The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus – The Lancet Psychiatry (free)
- Imaging changes in patients with 2019-nCov – European Radiology (free)
Preprints:
- Forecasting the Wuhan coronavirus (2019-nCoV) epidemics using a simple (simplistic) model – update (Feb. 8, 2020) – medRxiv (free PDF)
- Transmission and epidemiological characteristics of Novel Coronavirus (2019-nCoV)-Infected Pneumonia(NCIP):preliminary evidence obtained in comparison with 2003-SARS – medRxiv (free)
Selected News & Perspectives:
- China nCoV cases top 40,000, with more tied to French cluster – CIDRAP (free)
- “Containment” Is Objective Says WHO Head As New Coronavirus Clusters Emerge in France & UK; WHO Team Lands In China – Health Policy Watch (free)
- Over 30 Antiviral Drugs Being Tested Against Against Novel Coronavirus – As WHO Convenes Global Innovation Forum – Health Policy Watch (free)
- Coronavirus Is Bad. Comparing It to the Flu Is Worse – Wired (a few articles per month are free)
- Opinion: Africa is not fully ready for coronavirus – Devex (free)
- Global Solidarity, Collaboration and Urgent Action Needed to Defeat the New Coronavirus Outbreak – TIME (free)
- Coronavirus cases outside China ‘could be spark’ for bigger fire, says WHO – Reuters (free)
- Here is what WHO experts are watching on the coronavirus’ spread – Reuters (free)
- Countries rush to build diagnostic capacity as coronavirus spreads – Reuters (free)
- Fluctuating funding and flagging interest hurt coronavirus research, leaving crucial knowledge gaps – STAT (free)
- Wilson and Halabi: How global health rules are being challenged by coronavirus – Ottawa Citizen (free)
- Misinformation on the coronavirus might be the most contagious thing about it – The Guardian (free)
Mon February 10 – 10 Stories of The Day!
9 Feb, 2020 | 21:10h | UTC
Executive Summary: Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children (free)
2 – De-implementing wisely: developing the evidence base to reduce low-value care – BMJ Quality & Safety (free) (via @brhospitalist)
Commentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)
4 – Clinical Update: Diagnosis and Management of Primary Hyperparathyroidism – JAMA (free for a limited period)
5 – Potential Consequences of Changing Disease Classifications – JAMA (free for a limited period)
Author Interview: Potential Consequences of Changing Disease Classifications (free audio)
6 – Abolish the Tilt Table Test for the Workup of Syncope! – Circulation (free for a limited period)
7 – Dietary Modification and Breast Cancer Mortality: Long-Term Follow-Up of the Women’s Health Initiative Randomized Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Related: Commentaries before publication at the 2019 ASCO Annual Meeting (free)
9 – Novel Coronavirus – Selected News & Perspectives / 10 February 2020
See also: WHO: Novel Coronavirus (2019-nCoV) Situation Report – 9 February 2020 (free PDF)
- China nCoV cases continue at stable rate, concerns rise about spread in Singapore – CIDRAP (free)
- Coronavirus—Unknown Source, Unrecognized Spread, and Pandemic Potential – Think Global Health (free)
- WHO cautions that transmission of the new coronavirus outside of China could increase – STAT (free)
- New Report on 138 Coronavirus Cases Reveals Disturbing Details – The New York Times (10 articles per month are free)
- New study an eye-opener on how coronavirus is spreading and how little we know – CNN (free)
- Concerns mount about coronavirus spreading in hospitals, study suggests – CNN (free) A
- Demand for masks soars 100-fold, disrupting coronavirus fight: WHO – Reuters (free)
- China Begins Testing an Antiviral Drug in Coronavirus Patients – The New York Times (10 articles per month are free)
- Could an old malaria drug help fight the new coronavirus? – ASBMB (free)
- Did pangolins spread the China coronavirus to people? – Nature (free)
- Scientists question work suggesting pangolin coronavirus link – Reuters (free)
- The US coronavirus travel ban could backfire. Here’s how – CNN (free)
- Coronavirus: WHO chief warns against ‘trolls and conspiracy theories’ – BBC (free)
10 – Novel Coronavirus – Latest Articles / 10 February 2020
See also: WHO: Novel Coronavirus (2019-nCoV) Situation Report – 9 February 2020 (free PDF)
Guidelines:
- A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) – Military Medical Research (free)
- Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus – World Journal of Pediatrics (free)
Top Articles / Articles in High Impact Journals:
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China – JAMA (free) AND Commentaries: New study an eye-opener on how coronavirus is spreading and how little we know – CNN (free) AND Concerns mount about coronavirus spreading in hospitals, study suggests – CNN (free) AND New Report on 138 Coronavirus Cases Reveals Disturbing Details – The New York Times (10 articles per month are free)
- Preprint: Clinical characteristics of 2019 novel coronavirus infection in China – medRxiv (free PDF) (via @greg_folkers see Tweet) (Preprint with description of 1099 patients).
- Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China – JAMA (free)
- Novel coronavirus infection during the 2019–2020 epidemic: preparing intensive care units—the experience in Sichuan Province, China – Intensive Care Medicine (free)
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro – Cell Research (free) AND Commentaries: China Begins Testing an Antiviral Drug in Coronavirus Patients – The New York Times (10 articles per month are free) AND Could an old malaria drug help fight the new coronavirus? – ASBMB (free)
- Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (Manis javanica) – Viruses (free) AND Commentaries: Did pangolins spread the China coronavirus to people? – Nature (free) AND Scientists question work suggesting pangolin coronavirus link – Reuters (free)
- Scientists are racing to model the next moves of a coronavirus that’s still hard to predict – Science (free)
- China coronavirus: labs worldwide scramble to analyse live samples – Nature (free)
- Emerging Coronavirus 2019-nCoV Pneumonia – Radiology (free)
Podcast:
Other Articles:
- Offline: 2019-nCoV—“A desperate plea” – The Lancet (free)
- Game consumption and the 2019 novel coronavirus – The Lancet Infectious Diseases (free)
- Pathogenicity and Transmissibility of 2019-nCoV—A Quick Overview and Comparison with Other Emerging Viruses – Microbes and Infection (free)
- Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia – Clinical Chemistry (free PDF)
- 2019-Novel Coronavirus (2019-nCoV): estimating the case fatality rate – a word of caution – Swiss Medical Weekly (free)
- A contingency plan for the management of the 2019 novel coronavirus outbreak in neonatal intensive care units – The Lancet Child & Adolescent Health (free)
- Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed – The Lancet Psychiatry (free)
- Revisiting the dangers of the coronavirus in the ophthalmology practice – Eye (free)
- China bans sale of wildlife following coronavirus – VetRecord (free)
- Evolving status of the 2019 novel coronavirus Infection: proposal of conventional serologic assays for disease diagnosis and infection monitoring – Journal of Medical Virology (free PDF)
- Genomic variance of the 2019‐nCoV coronavirus – Journal of Medical Virology (free PDF)
- Novel coronavirus is putting the whole world on alert – The Journal of Hospital Infection (free)
- Estimating the Unreported Number of Novel Coronavirus (2019-nCoV) Cases in China in the First Half of January 2020: A Data-Driven Modelling Analysis of the Early Outbreak – Journal of Clinical Medicine (free PDF)
- Evolution of CT Manifestations in a Patient Recovered from 2019 Novel Coronavirus (2019-nCoV) Pneumonia in Wuhan, China – Radiology (free)
- CT Manifestations of Two Cases of 2019 Novel Coronavirus (2019-nCoV) Pneumonia – Radiology (free)
- Coronavirus in China – The Lancet Respiratory Medicine (free)
Preprints:
- Preparedness and vulnerability of African countries against introductions of 2019-nCoV – medRxiv (free PDF)
- Reconciling early-outbreak estimates of the basic reproductive number and its uncertainty: a new framework and applications to the novel coronavirus (2019-nCoV) outbreak – medRxiv (free PDF)
- Analysis of the epidemic growth of the early 2019-nCoV outbreak using internationally confirmed cases – medRxiv (free PDF)
- Incorporating Human Movement Data to Improve Epidemiological Estimates for 2019-nCoV – medRxiv (free PDF)
Fri February 7 – 10 Stories of The Day!
7 Feb, 2020 | 08:34h | UTC
Guideline Synopsis: Diagnosis and Treatment of Adults with Community-Acquired Pneumonia – JAMA (free for a limited period)
See also: Treatment Algorithm (free)
Original Article: ATS/IDSA Guideline: Diagnosis and Treatment of Adults with Community-acquired Pneumonia (free resources)
Related Guideline: NICE Guideline: Management of Pneumonia in Adults (free resources)
2 – Corticosteroids in Community-Acquired Pneumonia – JAMA (free for a limited period)
Related Meta-analysis: Efficacy and Safety of Adjunctive Corticosteroids Therapy for Severe Community-Acquired Pneumonia in Adults: An Updated Systematic Review and Meta-Analysis – PLOS One (free) AND Adjunctive Systemic Corticosteroids for Hospitalized Community-Acquired Pneumonia: Systematic Review and Meta-Analysis 2015 Update – Scientific Reports (free)
Related Cochrane Review: Is Treatment With Corticosteroids Beneficial for People With Pneumonia? (free)
3 – Nutrition therapy in critical illness: a review of the literature for clinicians – Critical Care (free)
Commentaries: The power of shared data to better understand drug safety – The BMJ Opinion (free) AND New study adds to evidence of diabetes drug link to heart problems – BMJ (free) AND Largest ever evaluation of the cardiovascular risk of rosiglitazone published – OnMedica (free) AND Individual patient data analysis firms up rosiglitazone safety verdict – medwire News (free)
Commentary: Start with Anti-TNF in RA? Not So Fast – RheumNow (free)
Commentary: Normal resting heart rate appears to vary widely from person to person – PLOS (free) AND Normal resting heart rate varies widely – OnMedica (free)
7 – Association of Maximal Extent of Resection of Contrast-Enhanced and Non–Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma – JAMA Oncology (free for a limited period)
Commentaries: A Common Rule for Resection of Glioblastoma in the Molecular Era – JAMA Oncology (free) AND Brain tumor surgery that pushes boundaries boosts patients survival – University of California (free) AND More aggressive surgery may improve brain cancer survival – UPI (free)
See also: WHO to accelerate research and innovation for new coronavirus – World Health Organization (free) AND Novel Coronavirus (2019-nCoV) advice for the public: Myth busters – World Health Organization (free) AND Novel Coronavirus (2019-nCoV) advice for the public: When and how to use masks – World Health Organization (free)
9 – Novel Coronavirus – Selected News & Perspectives / 07 February 2020
– W.H.O. Fights a Pandemic Besides Coronavirus: an ‘Infodemic’ – The New York Times (10 articles per month are free)
– Coronavirus: Everything you need to know in a visual explainer – South China Morning Post (free) (via @DrTomFrieden)
– Coronavirus Expert Reality Check – Global Health NOW (free)
– How the new coronavirus will finally get a proper name – BBC (free)
– WHO says too early to say coronavirus peaking in China – Reuters (free)
– WHO sees no sign of nCoV peak in China, cases rise overseas – CIDRAP (free)
10 – Novel Coronavirus – Latest Articles / 07 February 2020
– Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury – The Lancet (free PDF) See Commentary: Steroids could do more harm than good in treating coronavirus – University of Edinburgh (free)
– Reducing mortality from 2019-nCoV: host-directed therapies should be an option – The Lancet (free)
– Travelers Give Wings to Novel Coronavirus (2019-nCoV) – Journal of Travel Medicine (free PDF)
– Origin and evolution of the 2019 novel coronavirus – Clinical Infectious Diseases (free PDF)
– Editorial: Communication, collaboration and cooperation can stop the 2019 coronavirus – Nature (free)
– Updates on Wuhan 2019 Novel Coronavirus Epidemic – Journal of Medical Virology (free PDF)
– SARS to novel coronavirus – old lessons and new lessons – Epidemiology and Infection (free)
Preprints:
– Evidence and characteristics of human-to-human transmission of 2019-nCoV – medRxiv (free PDF)
– Modelling the epidemic trend of the 2019-nCOV outbreak in Hubei Province, China – medRxiv (free PDF)
– Epidemic doubling time of the 2019 novel coronavirus outbreak by province in mainland China – medRxiv (free PDF)
Thu February 6 – 10 Stories of The Day!
6 Feb, 2020 | 02:18h | UTC
1 – ACG Clinical Guideline: Chronic Pancreatitis – American Journal of Gastroenterology (free PDF)
2 – Lower versus Traditional Treatment Threshold for Neonatal Hypoglycemia – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Lower Treatment Threshold for Neonatal Hypoglycemia (free)
3 – Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Prenatal High-Dose Vitamin D Doesn’t Reduce Asthma Risk in Offspring – NEJM Journal Watch (free)
4 – Global genomics project unravels cancer’s complexity at unprecedented scale – Nature (free)
Editorial: The era of massive cancer sequencing projects has reached a turning point – Nature (free)
Commentaries: Landmark study to transform cancer treatment – BBC (free) AND Diving deep in the genomes of cancer – eCancer News (free)
See Articles:
– Pan-cancer analysis of whole genomes – Nature (free)
– Analyses of non-coding somatic drivers in 2,658 cancer whole genomes – Nature (free)
– The repertoire of mutational signatures in human cancer – Nature (free)
– Patterns of somatic structural variation in human cancer genomes – Nature (free)
– The evolutionary history of 2,658 cancers – Nature (free)
– Genomic basis for RNA alterations in cancer – Nature (free)
Commentaries: Healthy habits still vital after starting blood pressure, cholesterol medications – American Heart Association (free) AND People on blood pressure, cholesterol meds often let healthy habits slip – UPI (free)
Related: Moral Injury and Burnout in Medicine: A Year of Lessons Learned (free Commentaries) AND It’s time to talk about physician burnout and moral injury – The Lancet Psychiatry (free)
7 – Evaluation and Management of Sports-Related Eye Injuries – Current Sports Medicine Reports (free)
See also: US$675 million needed for new coronavirus preparedness and response global plan – World Health Organization (free) AND The Strategic Preparedness and Response Plan (SPRP) for the 2019 novel coronavirus – World Health Organization (free PDF)
9 – Novel Coronavirus – Selected News & Perspectives / 06 February 2020
– China marks biggest nCoV jump; WHO unveils response plan – CIDRAP (free)
– Experts offer first US nCoV clinical guidance – CIDRAP (free)
– Amid Coronavirus Fears, a Mask Shortage Could Spread Globally – Wired (free)
– Why the New Coronavirus (Mostly) Spares Children – New York Times (10 articles per month are free)
– Coronavirus: A visual guide to the outbreak – BBC (free)
– Coronavirus: Five things you need to know – BBC (free)
– Data suggests virus infections under-reported, exaggerating fatality rate – Reuters (free)
10 – Novel Coronavirus – Latest Articles / 06 February 2020
– 2019 Novel Coronavirus—Important Information for Clinicians – JAMA (free)
Wed February 5 – 10 Stories of The Day!
5 Feb, 2020 | 08:26h | UTC
See Resources: Toolkit for safe listening devices and systems (free PDF) AND Safe listening devices and systems: a WHO-ITU standard (free PDF)
3 – Association of Home Noninvasive Positive Pressure Ventilation With Clinical Outcomes in Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Commentary: In-home breathing device may offer hope for people with COPD – News Medical (free)
4 – Management of HIV-infected patients in the intensive care unit – Intensive Care Medicine (free)
5 – Vasopressin and its analogues in shock states: a review – Annals of Intensive Care (free)
Commentaries: Study shows advanced colorectal cancers at recommended screening age – Louisiana State University Health Sciences Center (free) AND Should Colon Cancer Screening Begin Before 50? – MedicalResearch.com (free)
Related: Another Study Points to Increased Colorectal Cancer Incidence in Young Adults (studies on the subject)
See also: WHO says Wuhan coronavirus outbreak is not yet a pandemic – CNN (free)
9 – Novel Coronavirus – Selected News & Perspectives / 05 February 2020
– Experts envision two scenarios if the new coronavirus isn’t contained – STAT (free)
– Coronavirus: Window of opportunity to act, World Health Organization says – BBC (free)
– Coronavirus Map: Tracking the Spread of the Outbreak – The New York Times (10 articles per month are free)
– nCoV total tops 20,000 as officials probe spread from nations outside of China – CIDRAP (free)
– Why are we panicked about coronavirus — and calm about the flu? – The Hill (free)
10 – Novel Coronavirus – Latest Articles / 05 February 2020
– Study claiming new coronavirus can be transmitted by people without symptoms was flawed – Science (free)
– Case Series: CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV) – Radiology (free PDF) See Commentary: Radiologists describe coronavirus imaging features – Radiology Society of North America (free)
– Interim US Guidance for Risk Assessment and Public Health Management of Persons with Potential 2019 Novel Coronavirus (2019-nCoV) Exposure in Travel-associated or Community Settings – Centers for Disease Control and Prevention (free) See Commentary: CDC Spells out Risk Levels for Novel Coronavirus – NEJM Journal Watch (free)
– Baricitinib as potential treatment for 2019-nCoV acute respiratory disease – The Lancet (free)
– Risk of 2019 novel coronavirus importations throughout China prior to the Wuhan quarantine – medRxiv (free PDF) See Commentary: Early spread of coronavirus extends far beyond China’s quarantine zone – University of Texas at Austin (free)
Tue February 4 – 10 Stories of The Day!
4 Feb, 2020 | 08:10h | UTC
1 – Recommended Adult Immunization Schedule, United States, 2020 – Annals of Internal Medicine (free)
Commentary: ACIP releases updated vaccination schedule with several changes – ACP Hospitalist (free)
Related: Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS®) Society and the European Society of Thoracic Surgeons (ESTS) – European Journal of Cardio-Thoracic Surgery (free) AND Enhanced recovery programs in lung cancer surgery: systematic review and meta-analysis of randomized controlled trials – Cancer Management and Research (free)
See also other Enhanced Recovery After Surgery (ERAS) Guidelines (free)
3 – WHO outlines steps to save 7 million lives from cancer – World Health Organization (free)
See Report: World Cancer Report: Cancer Research for Cancer Prevention – World Health Organization (free PDF)
Related: Is the world making progress against cancer? – Our World in Data (free)
5 – 2019 Update on Pediatric Medical Overuse: A Systematic Review – JAMA Pediatrics (free for a limited period)
6 – Assessment of C-Reactive Protein Diagnostic Test Accuracy for Late-Onset Infection in Newborn Infants: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
7 – Critical Care Nephrology: Core Curriculum 2020 – American Journal of Kidney Diseases (free)
Source: Grupo UTIclínica – HCFMUSP
See also: WHO Q&A on Coronaviruses (free) AND WHO Page on the Novel coronavirus (2019-nCoV) (free resources)
9 – Novel Coronavirus – Selected News & Perspectives / 04 February 2020
– The New Coronavirus Is a Truly Modern Epidemic – The Atlantic (free)
“New diseases are mirrors that reflect how a society works—and where it fails.”
– China Pledged to Build a New Hospital in 10 Days. It’s Close. – The New York Times (10 articles per month are free)
“State news outlets reported that the 1,000-bed facility would accept patients from Monday even as construction workers raced to complete it.”
– Coronavirus: Here Are 10 Misconceptions Being Spread – Forbes (free)
– China nCoV surge tops 17,000 as more vaccine support announced – CIDRAP (free)
– We need new forms of governance to better manage our response to pandemics – The BMJ Opinion (free)
10 – Novel Coronavirus – Latest Articles / 04 February 2020
– A new coronavirus associated with human respiratory disease in China – Nature (free PDF)
– A pneumonia outbreak associated with a new coronavirus of probable bat origin – Nature (free PDF)
Mon February 3 – 10 Stories of The Day!
2 Feb, 2020 | 20:27h | UTC
See also: WHO: Novel Coronavirus (2019-nCoV) Situation Report – 02 FEBRUARY 2020 – World Health Organization (free PDF)
2 – Novel Coronavirus – Selected News & Perspectives / 03 February 2020
– How Bad Will the Coronavirus Outbreak Get? Here Are 6 Key Factors – The New York Times (free)
– Why Travel Bans Don’t Work During An Outbreak Like Coronavirus – Forbes (free)
– 8 questions about the coronavirus outbreak, answered – Vox (free)
– Is reporting of the coronavirus producing viral panic? – The BMJ Opinion (free)
– Top WHO official says it’s not too late to stop the new coronavirus outbreak – STAT (free)
3 – Novel Coronavirus – Latest Articles / 03 February 2020
Wellcome Trust Statement: Sharing research data and findings relevant to the novel coronavirus (nCoV) outbreak (free)
– First Case of 2019 Novel Coronavirus in the United States – New England Journal of Medicine (free)
– Drug treatment options for the 2019-new coronavirus (2019-nCoV) – Bioscience Trends (free PDF)
– Novel Wuhan (2019-nCoV) Coronavirus – American Journal of Respiratory and Critical Care Medicine (free PDF)
4 – Electrical versus pharmacological cardioversion for emergency department patients with acute atrial fibrillation (RAFF2): a partial factorial randomised trial – The Lancet (link to abstract – $ for full-text)
Summary: Electrical vs Chemical Cardioversion in ED Patients With Atrial Fibrillation (RAFF2) – EMOttawa (free)
Related Study: Randomized Trial: Early vs. Delayed Cardioversion in Recent-Onset Atrial Fibrillation – New England Journal of Medicine (free study and commentaries)
Related Study: Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries – The Lancet (free)
Commentaries: New estimates of the number of cervical cancer cases and deaths that could be averted in low-income and lower-middle-income countries by scale-up of screening and vaccination activities – International Agency for Research on Cancer (free) AND Mass cervical cancer vaccine rollout could save 62 million lives in next 100 years – The Guardian (free)
6 – Clarifying the Language of Clinician Distress – JAMA (free for a limited period)
7 – Preprints can fill a void in times of rapidly changing science – STAT (free)
Commentaries: ‘Spring forward’ to daylight saving time brings surge in fatal car crashes – University of Colorado at Boulder (free) AND Daylight Saving Time Linked to More Deadly Car Crashes – Gizmodo (free)
9 – A systematic scoping review of clinical indications for induction of labour – PLOS One (free)
Commentary: New evidence supports advice not to drink alcohol in pregnancy – NHS Choices (free) AND Study backs up advice not to drink alcohol at all in pregnancy – OnMedica (free) AND Drinking alcohol during pregnancy: #Drymester the safest approach – University of Bristol (free)
Fri January 31 – 10 Stories of The Day!
31 Jan, 2020 | 01:40h | UTC
Situation Report: WHO: Novel Coronavirus (2019-nCoV) Situation Report – 30 JANUARY 2020 – World Health Organization (free PDF)
Commentaries: WHO declares coronavirus outbreak a global health emergency – STAT (free) AND The coronavirus outbreak is now a global health emergency, WHO says – Vox (free) AND WHO Declares Coronavirus Outbreak A Global Health Emergency – NPR (free) AND W.H.O. Declares Global Emergency as Wuhan Coronavirus Spreads – The New York Times (10 articles per month are free) AND WHO declares China virus outbreak an international emergency – Reuters (free)
Latest Articles: Viewpoint: The Novel Coronavirus Originating in Wuhan, China Challenges for Global Health Governance – JAMA (free) AND Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding – The Lancet (free) AND Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study – The Lancet (free)
Related guidelines: Cardio-Oncology: Vascular and Metabolic Perspectives: A Scientific Statement from the American Heart Association – Circulation (free PDF) AND Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Cardio-Onco-Hematology in Clinical Practice. Position Paper and Recommendations – Revista Espanola de Cardiologia (free)
3 – Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: NEJM: transcatheter aortic valve replacement shows similar safety outcomes as open-heart surgery – Smidt Heart Institute at Cedars-Sinai (free)
4 – Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany – JAMA (link to abstract – $ for full-text)
Commentary: General population screening reduces life-threatening diabetic ketoacidosis – JDRF (free)
5 – Antimicrobial-associated harm in critical care: a narrative review – Intensive Care Medicine (free for a limited period)
6 – What is new in decompressive craniectomy in neurological emergencies: the good, the bad and the ugly – Intensive Care Medicine (free for a limited period)
Related Systematic Review: Decompressive Craniectomy for the Treatment of High Intracranial Pressure in Closed Traumatic Brain Injury – Cochrane Library (free article, guideline and randomized trial)
7 – Cannabinoids for adult cancer-related pain: systematic review and meta-analysis – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Commentary: Cannabinoids No Help for Cancer Pain, Concludes Meta-Analysis – Medscape (free registration required)
Related: NICE Guideline: Cannabis-Based Medicinal Products (free guideline and resources on the subject)
8 – Outcomes of Online Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms: A Randomized Clinical Trial – JAMA Psychiatry (free for a limited period)
Commentary: Researcher: New online therapy for lingering depression symptoms could fill ‘gap in care’ – University of Toronto (free)
9 – Restrictive versus routine episiotomy among Southeast Asian term pregnancies: a multicentre randomised controlled trial – BJOG (link to abstract – $ for full-text)
Related Cochrane Review: Selective versus routine use of episiotomy for vaginal birth (free) AND Summary (free)
Source: FDA Strengthens Constipation Warning on Clozapine – NEJM Journal Watch (free)
Thu January 30 – 10 Stories of The Day!
30 Jan, 2020 | 07:51h | UTC
See also: WHO: Novel Coronavirus (2019-nCoV) Situation Report – 29 JANUARY 2020 – World Health Organization (free PDF) AND WHO Reconsiders Public Health Emergency Declaration Over Wuhan Coronavirus – As Cases Skyrocket – Health Policy Watch (free) AND WHO praises China’s response to coronavirus, will reconvene expert committee to assess global threat – STAT (free) AND WHO experts to again weigh nCoV emergency status as more nations affected – CIDRAP (free)
2 – Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Findings from NELSON trial affirm benefits of CT lung screening – AuntMinnie.com (free)
3 – Conservative versus Interventional Treatment for Spontaneous Pneumothorax – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: ‘Hands Off approach’ best to treat a collapsed lung – study – Voxy (free) AND Don’t Just Do Something, Stand There (Watching Spontaneous Pneumothoraces) – NEJM Journal Watch (free)
4 – Family History of Gastric Cancer and Helicobacter pylori Treatment – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Family History of Gastric Cancer and Helicobacter pylori Treatment (free)
Commentary: Antibiotic therapy cuts stomach cancer rate by more than half in high-risk population – Reuters (free)
5 – Colorectal cancer – National Institute for Health and Care Excellence (free)
7 – Sepsis and septic shock: Guideline-based management – Cleveland Clinic Journal of Medicine (free)
8 – Sickle cell disease: A primary care update – Cleveland Clinic Journal of Medicine (free)
10 – Malpractice Liability and Health Care Quality: A Review – JAMA (free for a limited period)
Editorial: Malpractice Liability and Quality of Care: Clear Answer, Remaining Questions – JAMA (free for a limited period)
Commentary: Malpractice-Avoidance Strategies Apparently Aren’t Improving Care Quality – NEJM Journal Watch (free)
Wed January 29 – 10 Stories of The Day!
29 Jan, 2020 | 08:32h | UTC
1 – Eliminating Medication Overload: A National Action Plan – Lown Institute (free PDF)
Press Release: Millions of Older Americans Harmed by Too Many Medications – Lown Institute (free)
Commentary: ‘Small’ tactics to counter Big Pharma’s influence on medication overload – STAT (free)
Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
4 – Novel Coronavirus (2019-nCoV) Situation Report – 28 JANUARY 2020 – World Health Organization (free PDF)
See also: WHO, China leaders discuss next steps in battle against coronavirus outbreak – World Health Organization (free) The Deceptively Simple Number Sparking Coronavirus Fears – The Atlantic (free) AND What Will It Take to Stop Coronavirus? – Harvard Business Review (free) AND The 2 key questions that will determine if the coronavirus outbreak becomes a pandemic – Vox (free) AND WHO seeks to answer nCoV unknowns as more local spread noted outside of China – CIDRAP (free) The coronavirus questions that scientists are racing to answer – STAT (free)
See Other Documents: Novel Coronavirus (2019-nCoV) technical guidance – World Health Organization (free)
6 – HIV infection and coronary heart disease: mechanisms and management – Nature Reviews Cardiology (free PDF)
7 – Association of Isolated Diastolic Hypertension as Defined by the 2017 ACC/AHA Blood Pressure Guideline With Incident Cardiovascular Outcomes – JAMA (free for a limited period)
Commentary: Isolated Diastolic Hypertension Using Tighter BP Cutoff Not Tied to Later CV Risk – NEJM Journal Watch (free)
8 – First-Trimester Pregnancy Exposure to Modafinil and Risk of Congenital Malformations – JAMA (free for a limited period)
Commentary: Modafinil in First Trimester Associated with Birth Defects – NEJM Journal Watch (free)
9 – Prevention of non-communicable disease: best buys, wasted buys, and contestable buys – The BMJ (free)
See also: Full BMJ Collection on Health, wealth, and profits (free articles)
10 – Leaving no woman, no child, and no adolescent behind – The BMJ (free articles)
News Release: Can we achieve health for all women, children, and adolescents by 2030? – Partnership for Maternal, Newborn and Child Health (free)
Tue January 28 – 10 Stories of The Day!
28 Jan, 2020 | 09:13h | UTC
2 – Smoking Cessation: A Report of the Surgeon General – U.S. Department of Health & Human Services (free)
News Release: Surgeon General Releases First Report Focused on Smoking Cessation in 30 Years – U.S. Department of Health & Human Services (free)
Commentaries: E-cigarettes don’t help smokers quit, U.S. Surgeon General says – UPI (free) AND New U.S. Surgeon General’s Report Focuses on Smoking Cessation Efforts – American College of Cardiology (free) AND Surgeon General Releases Report Focused on Smoking Cessation – The ASCO Post (free)
4 – Community-Based Hemoglobin A1C Testing in Barbershops to Identify Black Men With Undiagnosed Diabetes – JAMA Internal Medicine (free for a limited period)
Commentaries: Barbershop screenings may help find undiagnosed diabetes – Reuters (free) AND Diabetes testing at barbershops effective for screening black men – UPI (free)
Related Studies: Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops (free study and commentaries) AND Randomized Trial: Community-Based Interventions to Improve Cardiovascular Risk in High-Risk Patients (free study and commentaries) AND Cluster Randomized Trial: Sustainability of Blood Pressure Reduction in Black Barbershops (free study and commentaries)
5 – Implications of Abnormal Exercise Electrocardiography with Normal Stress Echocardiography – JAMA Internal Medicine (free for a limited period)
Commentaries: Implications of Abnormal Exercise ECG With Normal Stress Echo – American College of Cardiology (free) AND Positive Stress ECG + Normal Stress Echo = Slightly Increased Heart Risk – NEJM Journal Watch (free)
6 – #192 Dialysis for the Internist with Joel Topf MD – The Curbsiders Internal Medicine Podcast (free)
See also: Episode List
7 – Estimating the magnitude of cancer overdiagnosis in Australia – Medical Journal of Australia (free)
Commentary: 29,000 cancers overdiagnosed in Australia in a single year – The Conversation (free)
Related: Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Position Paper on Overdiagnosis and Action to be Taken – Wonca (free PDF) AND Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review (free) AND Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) AND Five warning signs of overdiagnosis – The Conversation (free) AND What is overdiagnosed cancer? And why does it matter? – Croakey (free) AND Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT (free) AND Preventing overdiagnosis and the harms of too much sport and exercise medicine – British Journal of Sports Medicine (free)
8 – Novel Coronavirus (2019-nCoV) Situation Report – 27 JANUARY 2020 – World Health Organization (free PDF)
9 – China coronavirus latest: how quickly does the virus spread? – Nature (free)
See also: Coronavirus More Infectious Than Suspected; China Expands Quarantine – Health Policy Watch (free) AND Experts: nCoV spread in China’s cities could trigger global epidemic – CIDRAP (free)
10 – WN-CoV: interim guidance for primary care – Public Health England (free)
Commentary: GPs Given China Coronavirus Guidance – Medscape (free registration required)
Related: Interim Guidance: Infection prevention and control during health care when novel coronavirus (nCoV) infection is suspected – World Health Organization (free PDF)
Mon January 27 – 10 Stories of The Day!
26 Jan, 2020 | 23:04h | UTC
1 – Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Low-dose aspirin may reduce preterm birth risk among first-time mothers – NIH News Releases (free) AND Daily aspirin may reduce preterm birth risk among first-time mothers – OnMedica (free)
2 – Novel Coronavirus (2019-nCoV) Situation Report – 25 JANUARY 2020 – World Health Organization (free PDF)
Editorial: Another Decade, Another Coronavirus – New England Journal of Medicine (free)
Perspective: A Novel Coronavirus Emerging in China — Key Questions for Impact Assessment – New England Journal of Medicine (free)
See also: Coronavirus Spurs China to Suspend Tours Abroad and Xi to Warn of a ‘Grave Situation’ – The New York Times (free) AND China coronavirus spread is accelerating, Xi Jinping warns – BBC (free)
4 – Homepage: The Lancet Articles on the Coronavirus Outbreak (free)
Studies: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China – The Lancet (free) AND A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster – The Lancet (free)
Editorial: Emerging understandings of 2019-nCoV – The Lancet (free)
Commentaries: A novel coronavirus outbreak of global health concern – The Lancet (free) AND Data sharing and outbreaks: best practice exemplified – The Lancet (free) AND New coronavirus can cause infections with no symptoms and sicken otherwise healthy people, studies show – STAT (free)
5 – Doubts rise about China’s ability to contain new coronavirus – CIDRAP (free)
Report 3: Transmissibility of 2019-nCoV – Imperial College London (free)
Executive Summary: British Society for Rheumatology guideline on diagnosis and treatment of giant cell arteritis – Rheumatology (free)
Related: Giant Cell Arteritis: An Updated Review of an Old Disease (free review and guidelines)
7 – Evolving Issues in Oxygen Therapy in Acute Care Medicine – JAMA (free for a limited period)
Related: Systematic Review: Higher vs. Lower Fraction of Inspired Oxygen or Targets of Arterial Oxygenation for Adults Admitted to the Intensive Care Unit (several studies on the subject)
8 – Alex Nowbar’s weekly journal review, 24 January 2020 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
10 – Morphine and Cardiovascular Outcomes Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes Undergoing Coronary Angiography – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Clopidogrel Interaction With Morphine in ACS Linked to More Ischemic Events – TCTMD (free)
Fri January 24 – 10 Stories of The Day!
24 Jan, 2020 | 08:35h | UTC
1 – Statement on the meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV) – World Health Organization (free) AND WHO Director-General’s statement on the advice of the IHR Emergency Committee on Novel Coronavirus (free)
See also: WHO declines to declare China virus outbreak a global health emergency – STAT (free) AND Coronavirus Is Spreading, but W.H.O. Says It’s Not a Global Emergency – The New York Times (10 articles per month are free) AND The coronavirus outbreak is not yet a global health emergency, WHO says – Vox (free) AND Wuhan lockdown ‘unprecedented’, shows commitment to contain virus: WHO representative in China – Reuters (free)
“Make no mistake. This is an emergency in China, but it has not yet become a global health emergency. It may yet become one.” (from WHO Director-General’s statement)
2 – Coronavirus Infections—More Than Just the Common Cold – JAMA (free for a limited period)
Commentary: NIH officials discuss novel coronavirus that recently emerged in China – NIH News Releases (free)
Commentary: Overuse of CT Scans for Suspected Pulmonary Embolism Persists – TCTMD (free)
Original Study: A Quantitative and Narrative Evaluation of Goodman and Gilman’s Pharmacological Basis of Therapeutics – Pharmacy (free)
Related: Authors of premier medical textbook didn’t disclose $11 million in industry payments (free commentary) AND Study: Undisclosed Financial Ties Between Guideline Writers and Pharmaceutical Companies (several resources on the subject)
Editorials: Corporate sponsorship of patient groups: It’s time for mandatory disclosure (free for a limited period) AND The prevalence of industry funding of patient groups – BMJ Opinion (free)
8 – Association of Low-Carbohydrate and Low-Fat Diets With Mortality Among US Adults – JAMA Internal Medicine (free for a limited period)
Commentaries: Expert reaction to study looking at low-carb and low-fat diets and risk of death in a US cohort – Science Media Centre (free) AND When It Comes To Healthy Dieting, It’s The Quality Of Nutrients That Counts – MedicalResearch.com (free)
9 – Teprotumumab for the Treatment of Active Thyroid Eye Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Teprotumumab bests placebo for active thyroid eye disease – MedicalXpress (free)
10 – Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Endometriosis drug reduces bleeding in women with fibroids – Reuters (free) AND Oral hormone-blocking drug may help with heavy menstrual bleeding – Thomas Jefferson University (free)
Thu January 23 – 10 Stories of The Day!
23 Jan, 2020 | 10:03h | UTC
News Releases: Report guides pediatricians in care of maltreated children, including pharmacotherapy – AAP News (free) AND Pediatricians and Child Psychiatrists Suggest Comprehensive Approach in Caring for Children who Have Been Maltreated – American Academy of Pediatrics (free)
Commentary: Pediatrics Groups Offer Guidance on Caring for Maltreated Children – NEJM Journal Watch (free)
4 – 2019 Novel Coronavirus (2019-nCoV), Wuhan, China – Centers for Disease Control and Prevention (free)
Report 2: Estimating the potential total number of novel Coronavirus cases in Wuhan City, China – Imperial College London (free)
See also: WHO Director-General’s statement on IHR Emergency Committee on Novel Coronavirus – World Health Organization (free) AND Wuhan, China Goes On Lockdown; WHO Postpones Decision On Public Health Emergency Over Virus Outbreak – Health Policy Watch (free) AND China locks down city of 11 million at epicenter of virus outbreak – Reuters (free) AND Coronavirus Live Updates: More Than 570 Infected, as City Is Put on Lockdown – The New York Times (10 articles per month are free) AND Newly Identified Coronavirus Has Killed 17 People, Chinese Health Officials Say – NPR (free) AND Editorial: Stop the Wuhan virus – Nature (free)
5 – Vaccination of Infants with Meningococcal Group B Vaccine (4CMenB) in England – New England Journal of Medicine (link to abstract – $ for full-text)
Related Study: Meningococcal B Vaccine and Meningococcal Carriage in Adolescents in Australia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Vaccine prevents deadly meningitis B in infants – Reuters (free)
6 – Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Systemic Absorption of Sunscreen: Balancing Benefits With Unknown Harms (free for a limited period)
Commentaries: Expert reaction to study looking at sunscreen ingredients and absorption into the blood – Science Media Centre (free) AND All Major Sunscreen Ingredients Absorbed Through the Skin – MedicalResearch.com (free) AND Sunscreen ingredients really do seep into the blood. Is that bad? – Reuters (free)
7 – Effect of Early Surgery vs Endoscopy-First Approach on Pain in Patients With Chronic Pancreatitis: The ESCAPE Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Tracing the Evidence to Address Painful Chronic Pancreatitis With Surgery (free)
See also: Visual Abstract
8 – Severe flu management: a point of view – Intensive Care Medicine (free)
Invited Commentary: Addressing the global cirrhosis epidemic: one size will not fit all – The Lancet Gastroenterology & Hepatology (free)
Related: Findings from the Global Burden of Disease Study 2017 – The Lancet / Institute for Health Metrics and Evaluation (free PDF)
Invited Commentary: Congenital heart disease: a global public health concern (free)
Related: Findings from the Global Burden of Disease Study 2017 – The Lancet / Institute for Health Metrics and Evaluation (free PDF)
Wed January 22 – 10 Stories of The Day!
22 Jan, 2020 | 09:47h | UTC
Commentary: Risk of kidney injury in contrast CT imaging overstated, experts say – UPI (free)
Related: Another Study Questions the Association of Contrast Use and Acute Kidney Injury (studies on the subject)
2 – Diagnosis and risk stratification of chest pain patients in the emergency department: focus on acute coronary syndromes. A position paper of the Acute Cardiovascular Care Association – European Heart Journal: Acute Cardiovascular Care (free for a limited period)
See also: US detects first novel coronavirus case, in traveler – CIDRAP (free) AND China virus toll rises to nine as pandemic fears grow – Reuters (free) AND First US case of Wuhan coronavirus confirmed by CDC – CNN (free) AND How quickly does the Wuhan virus spread? – Nature (free)
5 – E-cigarettes: how risky are they? – World Health Organization (free)
6 – Effect of Hydroxyethyl Starch vs Saline for Volume Replacement Therapy on Death or Postoperative Complications Among High-Risk Patients Undergoing Major Abdominal Surgery: The FLASH Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Hydroxyethyl Starch for Fluid Replacement Therapy in High-Risk Surgical Patients: Context and Caution (free for a limited period)
Related Cochrane Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People (free)
7 – Effect of Renal Denervation and Catheter Ablation vs Catheter Ablation Alone on Atrial Fibrillation Recurrence Among Patients with Paroxysmal Atrial Fibrillation and Hypertension: The ERADICATE-AF Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Improving Outcomes in Patients With Atrial Fibrillation and Hypertension (free for a limited period)
8 – Managing Clinical Uncertainty: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
9 – Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics: A Systematic Review and Meta-analysis – Diseases of the Colon & Rectum (link to abstract – $ for full-text)
Related: Randomized Trial: Antibiotic Avoidance Associated with Similar Long-term Outcomes in Uncomplicated Diverticulitis (randomized trials on the subject)
Related: Meta-analysis: Double Anti-thrombotic Therapy Safer than Triple Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease (studies on the subject)
Tue January 21 – 10 Stories of The Day!
21 Jan, 2020 | 03:46h | UTC
1 – Smoking greatly increases risk of complications after surgery – World Health Organization (free)
See also: Tobacco and Surgical outcomes: WHO Knowledge Summary
2 – As Coronavirus Outbreak Surges In China, WHO Calls For Emergency Meeting – Health Policy Watch (free)
See also: WHO calls for emergency meeting on new virus in China, as cases spread to health care workers – STAT (free) AND China Confirms New Coronavirus Spreads From Humans to Humans – The New York Times (10 articles per month are free) AND AND As virus spreads to more Chinese cities, WHO calls emergency meeting – Reuters (free)
Related: New Chinese virus ‘will have infected hundreds’ (free resources)
3 – Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline – The BMJ (free)
Commentary: Hilary Thomson: Grasping the nettle of narrative synthesis – The BMJ Opinion (free)
See also: Episode List
Commentary: Myths may worsen low back pain and promote ineffective treatments – Reuters (free)
8 – Acute Myocardial Infarction in Young Individuals – Mayo Clinic Proceedings (free)
9 – Alex Nowbar’s weekly research review, 17 January 2020 – BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Commentaries: Study questions routine troponin testing for ACS in geriatric patients with NSCs – Society for Academic Emergency Medicine (free) AND This Old Heart of Mine and Troponin Testing – The Skeptics Guide to EM (free)