Open access
Open access
Powered by Google Translator Translator

TOP 10 Medical News Stories

Mon September 16 – 10 Stories of The Day!

16 Sep, 2019 | 02:58h | UTC

 

1 – 2019 ACC Expert Consensus Decision Pathway on Risk Assessment, Management, and Clinical Trajectory of Patients Hospitalized With Heart Failure – Journal of the American College of Cardiology (free)

Key Points to Remember: ACC Consensus Decision Pathway for Heart Failure Hospitalizations – American College of Cardiology (free)

 

2 – Head injury: assessment and early management – National Institute for Health and Care Excellence (free)

Related Guidelines: Management of severe traumatic brain injury (first 24 hours) – Anaesthesia Critical Care & Pain Medicine (free) AND New Guidelines for the Management of Pediatric Severe Traumatic Brain Injury (free) AND CDC Guideline: Diagnosis and Management of Mild Traumatic Brain Injury Among Children (free) AND Italian guidelines on the assessment and management of pediatric head injury in the emergency department – Italian Journal of Pediatrics (free) AND Scandinavian guidelines for initial management of minor and moderate head trauma in children – BMC Medicine (free)

 

3 – Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation – The Lancet (free)

Commentaries: Comparing antibiotic, silver, and standard ventriculoperitoneal shunts – The Lancet (free)

AND Antibiotic-impregnated shunt could prevent hydrocephalus infections, save millions – News Medical (free) AND Innovative treatment to prevent common brain infection could save NHS 7 million pounds per year – University of Liverpool (free)

 

4 – Sacrospinous hysteropexy versus vaginal hysterectomy with uterosacral ligament suspension in women with uterine prolapse stage 2 or higher: observational follow-up of a multicentre randomised trial – The BMJ (free)

 

5 – Prevalence, Characteristics and Association of Obstructive Sleep Apnea with Blood Pressure Control in Patients with Resistant Hypertension – Annals of the American Thoracic Society (link to abstract – $ for full-text)

Commentaries: Most patients with resistant hypertension have sleep apnoea – OnMedica (free) AND More Severe OSA Leads to Higher Blood Pressure in Patients with Resistant Hypertension – American Thoracic Society (free) AND Obstructive Sleep Apnea Common in Patients with Resistant Hypertension – MedicalResearch.com (free)

 

6 – Food allergy prevention with early food introduction: New recommendations on introducing allergenic solids – Canadian Family Physician (free)

Original Guideline: Timing of introduction of allergenic solids for infants at high risk – Canadian Paediatric Society (free)

See also: AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease (free guideline and commentary)

 

7 – ACE inhibitors and ARBs: Managing potassium and renal function – Cleveland Clinic Journal of Medicine (free)

Editorial: ACE inhibitor and ARB therapy: Practical recommendations (free)

 

8 – Long Distance Tele-Robotic-Assisted Percutaneous Coronary Intervention: A Report of First-in-Human Experience – EClinicalMedicine (free)

Commentary: First-in-Human Telerobotic Coronary Intervention Procedures Published in EClinicalMedicine – Diagnostic and Interventional Cardiology (free)

 

9 – Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer – JAMA Oncology (free for a limited period)

Author Interview: Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer (free audio)

Commentaries: Antibiotics reduce survival rates in cancer patients taking immunotherapy – Imperial College London (free) AND Antibiotics prior to immunotherapy lower survival rate for cancer patients, study says – UPI (free)

 

10 – Effect of Metformin Plus Tyrosine Kinase Inhibitors Compared With Tyrosine Kinase Inhibitors Alone in Patients With Epidermal Growth Factor Receptor–Mutated Lung Adenocarcinoma: A Phase 2 Randomized Clinical Trial – JAMA Oncology (free for a limited period)

Commentary: Metformin Repurposed: Boosts Survival in TKI-Treated Lung Cancer – MedPage Today (free registration required)

 


Fri September 13 – 10 Stories of The Day!

13 Sep, 2019 | 08:41h | UTC

 

1 – Tuberculosis – National Institute for Health and Care Excellence (free)

Related: WHO Guidelines on Tuberculosis Infection Prevention and Control (free guidelines)

 

2 – The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis – The Lancet (free registration required)

Related Articles: Management of drug-resistant tuberculosis – The Lancet (free registration required) AND Challenges and controversies in childhood tuberculosis – The Lancet (free)

Editorial: Tuberculosis needs accelerated and continued attention (free)

Related: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free) AND Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment (free)

 

3 – Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial – The Lancet (free)

Commentaries: HEALTH for heavy menstrual bleeding: real-world implications – The Lancet (free) AND Heavy menstrual bleeding: Keyhole hysterectomy technique ‘more effective’ – BBC (free)

 

4 – Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials – Science Translational Medicine (free for a limited period)

Commentaries: Cancer drugs don’t always work as intended, researchers warn – Cold Spring Harbor Laboratory (free) AND Why Aren’t Cancer Drugs Better? The Targets Might Be Wrong – The New York Times (10 articles per month are free)

 

5 – Supercooling Extends Preservation Time of Human Livers – Nature Biotechnology (free)

Commentaries: Scientists triple storage time of human donor livers – NIH News Releases (free) AND ‘Supercool’ method triples organ survival – BBC (free) AND A Human Liver Can Be Cooled to –4 Degrees Celsius and Survive – The Atlantic (free)

 

6 – Combined lifestyle factors and risk of incident type 2 diabetes and prognosis among individuals with type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies – Diabetologia (free)

Commentary: Diabetes Risk Plummets by 75% When Multiple Risk Factors Tackled – Medscape (free registration required)

 

7 – Chest Radiograph Signs Suggestive of Pericardial Disease – American College of Cardiology (free)

 

8 – Vaccines for Health Care Personnel – Mayo Clinic Proceedings (free)

Related: Immunization of Health-Care Personnel: Recommendations of the Advisory Committee on Immunization Practices (ACIP) – Centers for Disease Control and Prevention (free) AND Vaccination of healthcare workers: A review – Human Vaccines & Immunotherapeutics (free)

 

9 – Pneumococcal Disease: A Systematic Review of Health Utilities, Resource Use, Costs, and Economic Evaluations of Interventions – Value in Health (free)

Related: Pneumococcal infection in adults: burden of disease – Clinical Microbiology and Infection (free) AND The remaining challenges of pneumococcal disease in adults – European Respiratory Review (free)

 

10 – Prospective Evaluation of Maternal Sleep Position Through 30 Weeks of Gestation and Adverse Pregnancy Outcomes – Obstetrics & Gynecology (free)

Commentary: Sleeping on back may not lead to worse pregnancy outcomes – Reuters (free)

 


Thu September 12 – 10 Stories of The Day!

12 Sep, 2019 | 10:51h | UTC

 

1 – Enhanced Recovery After Surgery (ERAS) Guidelines for Perioperative Care in Cesarean Delivery – American Journal of Obstetrics & Gynecology (free articles)

Part I: Guidelines for Antenatal and Preoperative care in Cesarean Delivery: Enhanced Recovery After Surgery Society Recommendations

Part II: Guidelines for intraoperative care in cesarean delivery: Enhanced Recovery After Surgery Society Recommendations

Part III: Guidelines for postoperative care in cesarean delivery: Enhanced Recovery After Surgery (ERAS) Society recommendations

Related: Guidelines for perioperative care in gynecologic/oncology: Enhanced Recovery After Surgery (ERAS) Society recommendations—2019 update – International Journal of Gynecological Cancer (free) AND Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 

2 – A Randomized Trial of Prenatal n−3 Fatty Acid Supplementation and Preterm Delivery – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Fish oil study fails to show reduction in premature babies – Reuters (free)

 

3 – Screening mammography outcomes: risk of breast cancer and mortality by comorbidity score and age – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)

Commentaries: More evidence screening mammograms not needed for many older women – Reuters (free) AND Mammography unlikely to benefit older women with chronic illnesses – Georgetown University Medical Center (free)

 

4 – Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth – JAMA Psychiatry (link to abstract – $ for full-text)

Author Interview: Associations Between Social Media Time and Internalizing and Externalizing Problems Among US Youth (free audio)

Commentaries: Social Media Use by Adolescents Linked to Internalizing Behaviors – Johns Hopkins Bloomberg School of Public Health (free) AND More Social Media Use Linked to More Depression and Anxiety in Teens – NEJM Journal Watch (free) AND Expert reaction to study looking at social media and adolescent mental health – Science Media Centre (free)

Related: Association of Screen Time and Depression in Adolescence (links to abstract and commentaries) AND The Adverse Effects of Social Media use on Young People’s Mental Health May be Caused by Exposure to Cyberbullying, Loss of Sleep, and Reduced Physical Activity (links to abstract and commentaries) AND Research: This Is Your Brain Off Facebook (free) AND Cohort Study: Social Media Use and Adolescent Mental Health (free) AND Supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn (free articles)

 

5 – Respiratory syncytial virus infection in adults – The BMJ (free for a limited period)

Related Reviews: Respiratory Syncytial Virus and Other Non-influenza Respiratory Viruses in Older Adults – Infectious Disease Clinics of North America (free) AND Respiratory Syncytial Virus infection: an illness for all ages – Clinics in Chest Medicine (free)

 

6 – Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial – The BMJ (free)

 

7 – Gluten Does Not Induce Gastrointestinal Symptoms in Healthy Volunteers: A Double-Blind Randomized Placebo Trial – Gastroenterology (free for a limited period)

Commentaries: Will Science Sway Beliefs About Gluten? – Gastroenterology (free for a limited period) AND One of The Most Rigorous Experiments We Have Shows Gluten Isn’t Bad For Healthy People – Science Alert (free) AND Quick Take: Gluten does not induce gastrointestinal symptoms in healthy volunteers – 2 Minute Medicine (free)

 

8 – How many premature deaths from pesticide suicide have occurred since the agricultural Green Revolution? – Clinical Toxicology (free)

Commentaries: Scale of suicides by pesticide poisoning revealed – University of Edinburgh (free) AND 15 million people worldwide may have died by suicide with pesticides – UPI (free)

Related: Suicide in the World: WHO Global Health Estimates (free report and commentaries) AND Preventing Suicide: A resource for pesticide registrars and regulators – World Health Organization (free PDF)

 

9 – Prevalence and Predictability of Low-Yield Inpatient Laboratory Diagnostic Tests – JAMA Network Open (free)

Commentary: Is that blood test really necessary? AI could help decide – Stanford Medicine (free)

 

10 – Opinion: Ban Flavored E-Cigarettes to Protect Our Children – The New York Times (10 articles per month are free)

Related: Trump administration prepares to ban flavored e-cigarettes – STAT (free) AND ATS Responds to FDA’s Promise of Future Action on Flavored E-Cigarettes – American Thoracic Society (free)

 


Wed September 11 – 10 Stories of The Day!

11 Sep, 2019 | 10:31h | UTC

 

1 – Suicide in the World: Global Health Estimates – World Health Organization (free PDF)

News Release: Suicide: one person dies every 40 seconds – World Health Organization (free)

Commentaries: One person dies by suicide every 40 seconds: new UN health agency report – UN News (free) Suicide kills one person every 40 seconds, says WHO – Reuters (free) AND One person dies every 40 seconds from suicide, WHO says – CNN (free)

 

2 – The Occupational Burden of Nonmalignant Respiratory Diseases. An Official American Thoracic Society and European Respiratory Society Statement – American Journal of Respiratory and Critical Care Medicine (free)

Commentaries: Occupational hazards account for more than one in ten people with range of lung diseases – American Thoracic Society (free) AND Respiratory Hazards at Work Linked to Disease for 1 in 10 People Worldwide – AJMC (free)

 

3 – Draft Recommendation Statement: Screening for Cognitive Impairment in Older Adults – U.S. Preventive Services Task Force (free)

Commentary: USPSTF: Evidence Lacking for Cognitive Screening in Older Adults – Physician’s Briefing (free)

 

4 – Effect of Corticosteroid-Sparing Treatment With Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients With Uveitis: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: Antimetabolite Therapy for Uveitis: Methotrexate or Mycophenolate? – JAMA Ophthalmology (free for a limited period) AND Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial – NIH News Releases (free)

 

5- Scientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy: A Review – JAMA Neurology (free for a limited period)

Related: Diagnosis and management of sensory polyneuropathy – The BMJ (free) AND Small‐fiber neuropathy: Expanding the clinical pain universe – Journal of the Peripheral Nervous System (free) AND Small-fiber neuropathy definition, diagnosis, and treatment – Neurological Sciences (free)

 

6 – Oral Fluoroquinolones and Risk of Mitral and Aortic Regurgitation – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Fluoroquinolones and Cardiac Valve Regurgitation Risk – American College of Cardiology (free) AND Commonly used antibiotics may lead to heart problems – University of British Columbia (free)

Related: Committee Recommends New Restrictions on the use of Fluoroquinolones (free report and commentaries) AND FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions (free statement and commentaries) AND FDA Warns About Increased Risk of Aortic Dissection and Ruptures of Aortic Aneurism with Fluoroquinolones (free report and commentaries) AND Fluoroquinolone use and serious arrhythmias: A nationwide case-crossover study – Resuscitation (link to abstract – $ for full-text)

 

7 – Ann Robinson’s journal review, 10 September 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 

8 – Hypertensive Crisis: Pearls and Pitfalls for the ED Physician – emDocs (free)

Related: ESC Council on hypertension position document on the management of hypertensive emergencies – European Heart Journal – Cardiovascular Pharmacotherapy (free) AND 7th Brazilian Guideline of Arterial Hypertension: Chapter 14 – Hypertensive Crisis – Arquivos Brasileiros de Cardiologia (free) AND Focused Update on Pharmacologic Management of Hypertensive Emergencies – Current Hypertension Reports (free)

 

9 – WHO To Revisit Guidelines On Ebola Survivors’ Care; Study Finds 5-fold Higher Mortality – Health Policy Watch (free)

Original Study: Subsequent mortality in survivors of Ebola virus disease in Guinea: a nationwide retrospective cohort study – The Lancet Infectious Diseases (free for a limited period)

See also: Mortality rates in Ebola survivors after hospital discharge could be five times higher compared with the general population – London School of Hygiene & Tropical Medicine (free)

 

10 – Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis – Anesthesia & Analgesia (free)

Infographic: Shiver Me Timbers: Magnesium and Postoperative Shivering (free)

Source: EvidenceAlerts

 


Tue September 10 – 10 Stories of The Day!

10 Sep, 2019 | 02:32h | UTC

 

1 – Canadian guideline for Parkinson disease – Canadian Medical Association Journal (free)

Related: Parkinson’s disease in adults – National Institute for Health and Care Excellence (NICE) Guideline (free) AND Choosing Wisely: five recommendations related to tests, treatments, and procedures at risk of inappropriateness in the cure of Parkinson’s disease (LIMPE-DISMOV Academy) – Neurological Sciences (free)

 

2 – Latin American consensus on uncomplicated recurrent urinary tract infection – International Urogynecology Journal (free)

Related Guideline: AUA/CUA/SUFU Guideline: Recurrent Uncomplicated Urinary Tract Infections in Women (free article and commentary)

 

3 – 2019 Update on Medical Overuse: A Review – JAMA Internal Medicine (free for a limited period)

 

4 – Effectiveness of Behaviorally Designed Gamification Interventions With Social Incentives for Increasing Physical Activity Among Overweight and Obese Adults Across the United States: The STEP UP Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentaries: Using a wearable device to exercise more? Add competition to improve results – University of Pennsylvania (free) AND Tracking your exercise more effective with competition, study says – CNN (free)

 

5 – #171 Lupus in Primary Care with Beth Jonas MD – The Curbsiders Internal Medicine Podcast (free audio and summary)

Related: 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus – Arthritis & Rheumatology (free) AND New EULAR Recommendations for the Management of Systemic Lupus Erythematosus (free guidelines) AND Systemic Lupus Erythematosus in Primary Care: An Update and Practical Messages for the General Practitioner – Frontiers in Medicine (free)

See also: Episode List

 

6 – Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management – Gut (free)

Related Review: Lactose Intolerance, Dairy Avoidance, and Treatment Options – Nutrients (free)

 

7 – Clinical Practice Guidelines for Childbearing Female Candidates for Bariatric Surgery, Pregnancy, and Post-partum Management After Bariatric Surgery – Obesity Surgery (free)

Related: Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care – Obesity Reviews (free) AND Fertility, Pregnancy and Lactation After Bariatric Surgery – a Consensus Statement from the OEGGG – Geburtshilfe und Frauenheilkunde (free) AND Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis – PLOS Medicine (free) AND Nutrition in Pregnancy Following Bariatric Surgery – Nutrients (free) AND Pregnancy after bariatric surgery: a narrative literature review and discussion of impact on pregnancy management and outcome – BMC Pregnancy and Childbirth (free)

 

8 – Malaria eradication within a generation: ambitious, achievable, and necessary – The Lancet (free registration required)

Homepage: The Lancet Commission on Malaria Eradication (free article and commentaries – registration required)

Commentaries: Malaria can and should be eradicated within a generation, declare global health experts – The Lancet (free) AND Malaria can be eradicated by 2050, say global experts – Reuters (free) AND Defeat malaria in a generation – here’s how – BBC (free) AND It’s ‘Ambitious’ — But Possible — to Eradicate Malaria by 2050, According to a Landmark Report – TIME (free)

 

9 – Short Review: Management of Staphylococcus aureus bacteremia in adults – Canadian Medical Association Journal (free for a limited period)

Related: Clinical Management of Staphylococcus aureus Bacteremia – JAMA (free) AND Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children (free)

 

10 – Anticoagulation After Surgical or Transcatheter Bioprosthetic Aortic Valve Replacement – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Anticoagulation After Bioprosthetic Valve Replacement or TAVR – American College of Cardiology (free) AND Anticoagulation May Be Safe After Bioprosthetic Aortic Valve Replacement – Cardiology Advisor (free) AND Oral Anticoagulation Post-AVR Safe but Not Routinely Needed: PARTNER II – TCTMD (free)

 


Mon September 9 – 10 Stories of The Day!

9 Sep, 2019 | 00:19h | UTC

 

1 – Criteria for Critical Care Infants and Children: PICU Admission, Discharge, and Triage Practice Statement and Levels of Care Guidance – Pediatric Critical Care Medicine (free)

Executive Summary: Criteria for Critical Care of Infants and Children: PICU Admission, Discharge, and Triage Practice Statement and Levels of Care Guidance – Pediatrics (free)

Commentaries: Critical Care for Infants and Children – Updated Guidance and Practice Statement Released – American Academy of Pediatrics (free) AND Updated recommendations, levels of care categorized for pediatric ICUs – MedicalXpress (free) AND ‘Explosive’ growth in PICUs prompt updated policy in levels, practice of critical care – AAP News (free)

 

2 – Physical activity guidelines: UK Chief Medical Officers’ report (free PDF)

News Release: New physical activity guidelines issued by UK Chief Medical Officers (free)

Commentaries: UK CMOs: When it comes to physical activity some is good, but more is better – The BMJ Opinion (free) AND Strengthen muscles as well as heart to stay fit and healthy, say top doctors – BBC (free) AND No such thing as too little exercise, says Chief Medical Officer, as ten minute minimum is scrapped – The Telegraph (free)

Related: ACSM Scientific Pronouncements: Physical Activity Guidelines for Americans (free)

 

3 – Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial – The Lancet (free)

Commentary: Long-term cardiovascular health after stopping pre-eclampsia – The Lancet (free)

 

4 – Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin — Preliminary Report – New England Journal of Medicine (free)

Editorial: Vaping-Induced Lung Injury (free)

Related: Imaging of Vaping-Associated Lung Disease – New England Journal of Medicine (free) AND Pulmonary Lipid-Laden Macrophages and Vaping – New England Journal of Medicine (free) AND Severe Pulmonary Disease Associated with Electronic-Cigarette–Product Use — Interim Guidance – Centers for Disease Control and Prevention (free)

Commentaries: CDC Says Number Of Possible Cases Of Vaping-Related Lung Illness Has Doubled – NPR (free) AND Cases of Vaping-Related Lung Illness Surge, Health Officials Say – The New York Times (10 articles per month are free) AND Pneumonia cases linked to vaping are still rising. And federal officials don’t know what’s causing them – STAT (free)

 

5 – Reporting and Interpretation of Randomized Clinical Trials – JAMA (free)

 

6 – What Is Known About Candida auris – JAMA (free for a limited period)

Related: Global Epidemiology of Emerging Candida Auris (reviews and commentaries on the subject)

 

7 – A systematic review of clinical guidelines on the management of acute, community-acquired CNS infections – BMC Medicine (free)

Related: The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults (free) AND ESCMID guideline: diagnosis and treatment of acute bacterial meningitis (free) AND Meningitis (bacterial) and meningococcal septicaemia in under 16s: recognition, diagnosis and management – National Institute for Health and Care Excellence (free) AND Management of suspected viral encephalitis in adults – Association of British Neurologists and British Infection Association National Guidelines (free) AND Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines (free)

 

8 – An evidence‐based approach to developing low‐carbohydrate diets for type 2 diabetes management: A systematic review of interventions and methods – Diabetes, Obesity and Metabolism (free)

Source: EvidenceAlerts

 

9 – Assessment and Treatment of Patients with Type 2 Myocardial Infarction and Acute Non-Ischemic Myocardial Injury – Circulation (free PDF)

Related Reviews: A systematic review on the triggers and clinical features of type 2 myocardial infarction – Clinical Cardiology (free) AND Type 2 Myocardial Infarction: An Evolving Entity – Circulation Journal (free)

 

10 – Occupational Cardiology Series: Cardiovascular Assessment of Aircrew and Other High-hazard Employees – European Heart Journal (free articles)

– An Introduction to Occupational Cardiology: Cardiovascular assessment of aircrew and other high-hazard employees. The first article of the series

– Assessment of clinical and occupational cardiovascular risk: This second article in the occupational cardiology series discusses risk for the individual worker, the remainder of the workforce and the public in high-hazard occupations

– Electrophysiologic assessment of aircrew and other high-hazard employees: This third article in the occupational cardiology series focusses on the assessment of arrhythmias in high-hazard employees and how, not all arrhythmias prevent employment

– ECG interpretation: Interpretation of the ECG in young, fit, asymptomatic individuals undertaking high-hazard occupations is the topic of the fourth article in the occupational cardiology series

 


Fri September 6 – 10 Stories of The Day!

6 Sep, 2019 | 10:27h | UTC

 

1 – Twin and triplet pregnancy – National Institute for Health and Care Excellence (free)

 

2 – Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation – Cochrane Library (free)

Summary: Antiarrhythmics for maintaining sinus rhythm (normal heartbeat) after reversing atrial fibrillation (correcting an irregular heartbeat) – Cochrane Library (free)

 

3 – Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: QoL Better With Laser Ablation, Surgery for Varicose Veins – Drugs.com (free) AND Laser and Surgery Rule for Varicose Veins – MedPage Today (free registration required)

 

4 – Risk Factors and Outcomes Associated With Treatment of Asymptomatic Bacteriuria in Hospitalized Patients – JAMA Internal Medicine (free for a limited period)

Commentary: Asymptomatic Bacteriuria Often Inappropriately Treated With Antibiotics – Medscape (free registration required)

 

5 – American Society for Clinical Pathology: Thirty Things Physicians and Patients Should Question – Choosing Wisely (free)

Commentary: “Choosing Wisely” Calls Out Inappropriate Testing in Patients with Diarrhea or Hepatitis C – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

6 – Ann Robinson’s journal review, 5 September 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 

7 – HbA1c level as a risk factor for retinopathy and nephropathy in children and adults with type 1 diabetes: Swedish population based cohort study – The BMJ (free)

Commentaries: Microvascular benefits of lowest HbA1c target in type 1 diabetes questioned – Medwire News (free) AND How blood sugar levels affect risks in type 1 diabetes – University of Gothenburg (free) AND HbA1c levels of 6.5-7.0 percent may be optimal for adults and children with T1D – Univadis (free registration required)

 

8 – Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study – The BMJ (free)

Editorial: Vegetarian diets and health (free)

Commentaries: Vegetarian Diet Linked to Lower Heart Disease, But Higher Stroke Risks – NEJM Journal Watch (free) AND Vegetarians and pescatarians have lower risk of CHD – OnMedica (free) AND Expert reaction to study on meat-eating, fish-eating and vegetarian diets and risk of heart disease and stroke – Science Media Centre (free)

 

9 – Designing better sugary drink taxes – Science (link to abstract – $ for full-text)

News Release: Taxing Sweetened Drinks by the Amount of Sugar Could Cut Obesity & Boost Economic Gains – NYU (free) AND Experts Say Tax the Sugar—Not the Size—Of Drinks for Healthier Outcomes – AAAS (free) AND A New Soda Tax Strategy Directly Addresses the Real Cost of Sugar – Inverse (free)

Related: Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake (free study and resources on the subject)

 

10 – Potential impact on prevalence of obesity in the UK of a 20% price increase in high sugar snacks: modelling study – The BMJ (free)

Editorial: Taxing confectionery, biscuits, and cakes to control obesity (free) AND

Commentaries: Snack tax may be more effective than a sugary drink tax to tackle obesity – The BMJ (free) AND What next for fiscal interventions to prevent obesity? – The BMJ Opinion (free) AND Taxing sugary foods would cut prevalence of obesity – OnMedica (free) AND Snack tax may be more effective than a sugary drink tax to tackle obesity – London School of Hygiene & Tropical Medicine (free)

Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND  The Lancet taskforce on NCDs and economics (free series and commentaries) To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Reducing cardiovascular disease burden through targeted dietary policies (free study and commentaries) AND Fiscal policies for the prevention of diseases (free study and commentary) AND The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities (free)

 


Thu September 5 – 10 Stories of The Day!

5 Sep, 2019 | 08:32h | UTC

 

1 – Report: Essential Nutrition Actions: mainstreaming nutrition throughout the life course – World Health Organization (free PDF)

News Release: Stronger focus on nutrition within health services could save 3.7 million lives by 2025 – World Health Organization (free)

Commentaries: Healthier Diets Key To Reducing Obesity And NCDs: Says New WHO Report – Health Policy Watch (free) AND 3.7 million lives could be saved by 2025 if health services ramp up nutrition actions: WHO – UN News (free)

 

2 – Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea – JAMA Network Open (free)

 

3 – N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Respiratory Protection of Health Care Personnel to Prevent Respiratory Viral Transmission (free for a limited period)

Commentaries: Outpatient study finds masks, respirators equally protective – CIDRAP (free) AND Surgical masks as good as respirators for flu and respiratory virus protection – UT Southwestern Medical Center (free)

 

4 – Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Quick Take: Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL) – 2 Minute Medicine (free)

 

5 – Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF) AND Journal Citation in Prehospital Emergency Care (free)

 

6 – Vaping appears to be making hundreds of people sick. No one knows exactly why. – Vox (free)

Related: CDC Flags One Death and Nearly 200 Cases of Lung Illnesses in U.S., Possibly Tied to Vaping (free) AND Another Patient Has Died From Lung Disease After Vaping – The New York Times (10 articles per month are free)

 

7 – Artificial intelligence in medicine raises legal and ethical concerns – The Conversation (free)

Related: Artificial Intelligence Is Infiltrating Medicine — But Is It Ethical? – Forbes (free) AND Artificial Intelligence in Health Care – AMA Journal of Ethics (free articles)

 

8 – Pharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library (free)

Summary: Medicines to treat delirium in critically ill adult patients – Cochrane Library (free)

Related Systematic Reviews: Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free) AND Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 

9 – Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)

Related: USPSTF Recommendation Statement: Medication Use to Reduce Risk of Breast Cancer (free)

 

10 – Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease – JAMA (free for a limited period)

Commentary: Sustained drop in cholesterol and blood pressure reduces lifetime risk of heart, circulatory diseases – News Medical (free)

 


Wed September 4 – 10 Stories of The Day!

4 Sep, 2019 | 09:35h | UTC

 

1 – Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study – The Lancet (free until Sept 10 – registration required)

Related Study: Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study – The Lancet (free until Sept 10 – registration required)

Commentaries: Cancer now leading cause of death in high-income countries — while heart disease burden persists in low-income and middle-income countries – The Lancet (free) AND Cardiovascular Disease Leading Cause of Death World-Wide, but Cancer Rising Cause in Rich Countries: Study – McMaster University (free) AND Cancer ‘biggest middle-age killer in rich nations’ – BBC (free) AND Cancer overtakes heart disease as biggest rich-world killer – Reuters (free) AND Cancer now tops heart disease as the No. 1 cause of death in these countries – CNN (free)

 

2 – Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Recommendation Summary: Medication Use to Reduce Risk of Breast Cancer (free)

Editorials: Medications to Reduce Breast Cancer Risk: Promise and Limitations (free for a limited period) AND Breast Cancer Chemoprevention—Can We Make a Case for Precision Medicine? (free for a limited period)

Evidence Report and Systematic Review: Medication Use for the Risk Reduction of Primary Breast Cancer in Women – US Preventive Services Task Force (free)

Author Interview: USPSTF Recommendation: Medication Use to Reduce Risk of Breast Cancer (free audio)

Commentaries: Medication can lower some women’s risk of breast cancer – Reuters (free) AND USPSTF: Aromatase Inhibitors Recommended to Help Prevent Breast Cancer – NEJM Journal Watch (free)

 

3 – British Heart Rhythm Society Clinical Practice Guidelines on the Management of Patients Developing QT Prolongation on Antipsychotic Medication – Arrhythmia & Electrophysiology Review (free)

 

4 – How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) – European Heart Journal (free)

 

5 – Resistant Hypertension Updated Guidelines – Current Cardiology Reports (free)

Related: AHA Guideline: Resistant Hypertension (free) AND 7th Brazilian Guideline of Arterial Hypertension: Chapter 13 – Resistant Arterial Hypertension (free)

 

6 – What Statistics Can and Can’t Tell Us About Ourselves – The New Yorker (free)

 

7 – News Release: Oxygen is neither beneficial nor harmful in patients with acute coronary syndrome – European Society of Cardiology (free)

Commentary: Supplemental Oxygen Fails Once Again in ACS Patients: NZOTACS – TCTMD (free)

Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Systematic Review: Effects of Hyperoxia in Acutely Ill Patients(free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)

 

8 – Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements – BMJ Open (free)

Related Guidelines: 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free) AND Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)

 

9 – Overdiagnosis of COPD in Subjects With Unobstructed Spirometry – CHEST (link to abstract – $ for full-text)

Commentary: How Many Patients with Diagnosed COPD Truly Have It? – NEJM Journal Watch (free for a limited period)

 

10 – Association Between Soft Drink Consumption and Mortality in 10 European Countries – JAMA Internal Medicine (free for a limited period)

Commentaries: Large European Study Links Soda Consumption to Greater Risk of Mortality, Including From Parkinson – AJMC (free) AND Want to live longer? You may want to ditch these drinks – CNN (free) AND Soft drinks, including sugar-free, linked to increased risk of early death – The Guardian (free) AND Soft drinks – sugared or low-calorie – may raise the risk of early death – Reuters (free)

 


Tue September 3 – 10 Stories of The Day!

3 Sep, 2019 | 02:01h | UTC

 

1 – Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice. An Official American Thoracic Society Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine (free)

Commentary: New ATS Clinical Practice Guideline: Diagnosing Fungal Infections – American Thoracic Society (free)

 

2 – Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 

3 – Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 

4 – Antithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: AFIRE Supports Rivaroxaban Monotherapy in A-fib Patients With Stable CAD – TCTMD (free) AND Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease – AFIRE – American College of Cardiology (free)

Related: Meta-Analysis of Oral Anticoagulant Monotherapy as an Antithrombotic Strategy in Patients With Stable Coronary Artery Disease and Nonvalvular Atrial Fibrillation – American Journal of Cardiology (link to abstract – $ for full-text)

 

5 – Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial – The Lancet (link to abstract – $ for full-text)

Commentary: Bypass surgery and coronary stenting yield comparable 10-year survival – European Society of Cardiology (free)

Related Meta-Analysis: Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease (link to abstract) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis (free)

 

6 – Association of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity – JAMA (free for a limited period)

Editorial: The Role of Bariatric Surgery in Managing the Macrovascular Complications of Obesity-Related Type 2 Diabetes (free for a limited period)

Commentaries: Weight-Loss Surgery Associated with 40% Reduction in Risk of Death and Heart Complications in Patients with Diabetes and Obesity, Study Shows – Cleveland Clinic (free) AND Fewer cardiovascular events seen in diabetics after weight-loss surgery – Reuters (free) AND Metabolic Surgery Improves CV Outcomes in Patients With Diabetes, Obesity – American College of Cardiology (free) AND Weight-Loss Surgery May Reduce Heart Risks in People With Type 2 Diabetes – The New York Times (10 articles per month are free)

Related Studies: Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events (link to abstract) AND Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)

 

7 – Contraceptive eligibility for women at high risk of HIV: Guidance statement – Recommendations on contraceptive methods used by women at high risk of HIV – World Health Organization (free PDF)

News Release: WHO revises recommendations on hormonal contraceptive use for women at high HIV risk (free)

Commentary: WHO: All Forms of Contraception OK for Women at High HIV Risk – MedPage Today (free registration required)

Related Randomized Trial: No Difference in HIV Incidence with Different Forms of Contraception (free study and commentaries)

 

8 – Study Finds No ‘Gay Gene,’ But Some Question Whether The Search Should Have Started At All – CommonHealth (free)

Original Study: Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior – Science (free for a limited period)

Other commentaries: No ‘gay gene’: Massive study homes in on genetic basis of human sexuality – Nature (free) AND Genetics may explain up to 25% of same-sex behavior, giant analysis reveals – Science (free) AND Search For ‘Gay Genes’ Comes Up Short In Large New Study – NPR (free) AND Many Genes Influence Same-Sex Sexuality, Not a Single ‘Gay Gene’ – The New York Times (10 articles per month are free) AND No single gene associated with being gay – BBC (free)

 

9 – A community-based comprehensive intervention to reduce cardiovascular risk in hypertension (HOPE 4): a cluster-randomised controlled trial – The Lancet (free registration required)

Commentaries: Non-physician health workers lead new approach to lowering risk of world’s number one cause of death – The Lancet (free) AND Nonphysician, Community Intervention Curbs CV Risk Factors: HOPE 4 – TCTMD (free) AND It takes a community to lower cardiovascular risk – McMaster University (free)

 

10 – World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions – The Lancet Global Health (free)

Invited Commentary: Cardiovascular disease risk prediction models: challenges and perspectives (free)

 


Mon September 2 – 10 Stories of The Day!

2 Sep, 2019 | 01:22h | UTC

 

1 – 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: The Task Force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC)

News Release: Pollution and noise reduction advised in ESC guidelines on chronic coronary syndromes (free)

 

2 – 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC) (free)

 

3 – The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC): Developed in collaboration with the Association for European Paediatric and Congenital Cardiology (AEPC) (free)

 

4 – 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) (free)

 

5 – 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: The Task Force for diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD) (free)

 

6 – Maximum-fixed energy shocks for cardioverting atrial fibrillation – European Heart Journal (free)

Commentary: Comparison of High vs. Escalating Shocks – CHESS – American College of Cardiology (free)

 

7 – Complete Revascularization with Multivessel PCI for Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Complete Versus Culprit-Only Revascularization Strategies to Treat Multivessel Disease After Early PCI for STEMI – COMPLETE – American College of Cardiology (free) AND Complete revascularisation is superior to culprit-lesion only intervention – European Society of Cardiology (free)

Related Cochrane Review: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (free)

Related Meta-analysis: Complete Revascularization During Primary Percutaneous Coronary Intervention Reduces Death and Myocardial Infarction in Patients With Multivessel Disease: Meta-Analysis and Meta-Regression of Randomized Trials – JACC: Cardiovascular Interventions (free)

 

8 – Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction – DAPA-HF – American College of Cardiology (free) Dapagliflozin reduces death and hospitalisation in patients with heart failure – European Society of Cardiology (free)

 

9 – HiSTORIC Trial Supports Single-Test Rule-Out of MI Using High-Sensitivity Troponin – TCTMD (free) AND Risk-Based Thresholds for hs-Troponin I Safely Speed MI Rule-Out – MedPage Today (free registration required) AND HISTORIC: Early Rule-Out Strategy Using High-Sensitivity Cardiac Troponin I Reduced Length of Stay, Hospital Readmissions in Suspected ACS Patients – American College of Cardiology (free)

Related Studies: Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival (free study and commentaries)

 

10 – High-Sensitivity Troponin and The Application of Risk Stratification Thresholds in Patients with Suspected Acute Coronary Syndrome – Circulation (free PDF)

 


Fri August 30 – 10 Stories of The Day!

30 Aug, 2019 | 08:59h | UTC

 

1 – Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence – The Lancet (free)

Commentaries: Menopausal hormones: definitive evidence for breast cancer – The Lancet (free) AND Menopausal hormone therapy and 20-year breast cancer mortality – The Lancet (free) AND Hormone therapy during menopause raises breast cancer risk for years, study finds – STAT (free) AND Expert reaction to study looking at HRT use and risk of breast cancer – Science Media Centre (free)

 

2 – WHO joins coalition for free digital access to health research – World Health Organization (free)

See also: World Health Organization and TDR Join cOAlition S to Support Free and Immediate Access to Health Research – Plan S (free)

Related: Plan S: Making Full and Immediate Open Access a Reality (free) AND Open Access 2018: A Year of Funders and Universities Drawing Lines in the Sand (free)

 

3 – Is IJ or Subclavian Safer Under Ultrasound Guidance? – Journal Feed (free)

Original Article: Complications in internal jugular vs subclavian ultrasound-guided central venous catheterization: a comparative randomized trial – Intensive Care Medicine (free)

 

4 – News Release: FDA recommends health care facilities and manufacturers begin transitioning to duodenoscopes with disposable components to reduce risk of patient infection – U.S. Food & Drug Administration (free)

Commentaries: FDA: Hospitals Should Start Switching to Duodenoscopes with Disposable Endcaps – NEJM Journal Watch (free) AND Hospitals Should Replace Infection-Prone Scopes With Safer Models, F.D.A. Says – The New York Times (10 articles per month are free) AND FDA Urges Transition to Disposable Duodenoscopes – Medscape (free registration required)

Related: Duodenoscopes: These Medical Devices Are Inserted Into 500,000 Patients Each Year — but Are Tough to Sterilize (free commentary, reviews and guidelines)

 

5 – Medical education needs to stop burning out students — now – STAT (free)

Related: Meta-analysis: The Global Prevalence of Anxiety Among Medical Students (free studies)

 

6 – RoB 2: a revised tool for assessing risk of bias in randomised trials – The BMJ (free)

 

7 – Screening for Social Determinants of Health: The Known and Unknown – JAMA (free)

Commentary: JAMA paper: Doctors encouraged to consider social determinants screening, referrals – Northwell Health (free)

 

8 – Initiation of sodium polystyrene sulphonate and the risk of gastrointestinal adverse events in advanced chronic kidney disease: a nationwide study – Nephrology Dialysis Transplantation (free)

Commentary: Hyperkalemia Drug Again Linked to Adverse GI Events – Renal & Urology News (free)

Related Study: Risk of Hospitalization for Serious Adverse Gastrointestinal Events Associated with Sodium Polystyrene Sulfonate (link to abstract and commentary)

 

9 – Use of sodium glucose cotransporter 2 inhibitors and risk of major cardiovascular events and heart failure: Scandinavian register based cohort study – The BMJ (free)

Commentaries: SGLT2 inhibitors cut heart failure risk for T2D patients – Cardiovascular Business (free) AND Newer diabetes drug drops heart failure risk by 34 percent, study says – UPI (free)

Related observational studies: SGLT2 agents may reduce cardiovascular risk in diabetics (link to abstract and commentaries)

 

10 – Intake of Dietary Fiber, Fruits, and Vegetables and Risk of Diverticulitis – American Journal of Gastroenterology (link to abstract – $ for full-text)

Commentary: More fruit and cereal fiber tied to less risk of common bowel disease – Reuters (free)

 


Thu August 29 – 10 Stories of The Day!

29 Aug, 2019 | 10:23h | UTC

 

1 – Type 2 diabetes in adults: management – National Institute for Health and Care Excellence (free)

Related Guideline: ADA 2019 Standards of Medical Care in Diabetes (free supplement)

 

2 – Hypertension in adults: diagnosis and management – National Institute for Health and Care Excellence (free)

Related Guidelines: 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (free) AND 2018 ESC/ESH Guidelines for the management of arterial hypertension – European Heart Journal (free)

 

3 – Clinical guidelines for the management of treatment-resistant depression: French recommendations from experts, the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental – BMC Psychiatry (free)

Related Guidelines: Clinical guidelines for the management of depression with specific comorbid psychiatric conditions French recommendations from experts (the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental) – BMC Psychiatry (free) AND Depression in adults: recognition and management – National Institute for Health and Care Excellence (free)

 

4 – Effect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentaries: Vasopressin as an Early Adjunct to Resuscitation in Hemorrhagic Shock: Crisis AVERTed? – JAMA Surgery (free) AND Giving trauma patients blood pressure stabilizing hormone cuts transfusions by half – University of Pennsylvania School of Medicine (free)

Author Interview: Arginine Vasopressin Supplementation in Early Traumatic Shock (free)

“Additional research is necessary to determine whether including AVP improves morbidity or mortality.”

 

5 – Age and Sex Estimation Using Artificial Intelligence From Standard 12-Lead ECGs – Journal of the American Heart Association (free)

Commentary: Applying AI to ECG data helps gauge patients’ ‘physiologic age’ – Cardiovascular Business (free) AND Artificial intelligence-enabled EKG could predict overall health status – UPI (free)

 

6 – Association of Cesarean Delivery With Risk of Neurodevelopmental and Psychiatric Disorders in the Offspring: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: There’s no evidence caesarean sections cause autism or ADHD – The Conversation (free) AND Expert reaction to study on caesareans and neurodevelopmental disorders – Science Media Centre (free)

 

7 – Cesarean section and the risk of neonatal respiratory distress syndrome: a meta-analysis – Archives of Gynecology and Obstetrics (free)

 

8 – Association Between Hormone Therapy and Muscle Mass in Postmenopausal Women: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentary: Hormone Therapy Doesn’t Prevent Age-Related Muscle Loss in Women – Medscape (free registration required)

 

9 – Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans – Cell Metabolism (free for a limited period)

Commentaries: Alternate-day fasting associated with weight loss – Reuters (free) AND Clinical trial shows alternate-day fasting a safe alternative to caloric restriction – Cell Press (free)

 

10 – Gout and the risk of advanced chronic kidney disease in the UK health system: a national cohort study – BMJ Open (free)

Commentaries: Gout ‘more than doubles’ risk of kidney failure – University of Limerick (free) AND Gout pushes up kidney disease risks, study says – UPI (free)

 


Wed August 28 – 10 Stories of The Day!

28 Aug, 2019 | 05:53h | UTC

 

1 – Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: High-Dose Vitamin D Might Reduce Bone Mineral Density – NEJM Journal Watch (free)

 

2 – Draft Recommendation Statement: Hepatitis C Virus Infection in Adolescents and Adults: Screening – U.S. Preventive Services Task Force (free)

Commentary: HCV Screening Now Recommended for All Adults – NEJM Journal Watch (free)

 

3 – Screening and Management of Bleeding Disorders in Adolescents With Heavy Menstrual Bleeding: ACOG Committee Opinion Summary – Obstetrics & Gynecology (free)

Commentary: ACOG advises bleeding disorder screening for teens with heavy menstruation – ObGyn News (free)

 

4 – How to start an antimicrobial stewardship programme in a hospital – Clinical Microbiology and Infection (free)

 

5 – Increased Risk of All Cardiovascular Disease Subtypes Among Childhood Cancer Survivors: Population-Based Matched Cohort Study – Circulation (free PDF)

Commentaries: Childhood cancer survivors face variety of heart risks – Reuters (free) AND Childhood cancer survivors 10 times more likely to develop heart failure – UPI (free)

Related Research: Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors (free)

 

6 – How many older adults receive drugs of questionable clinical benefit near the end of life? A cohort study – Palliative Medicine (free)

Related Studies: Use of Medications of Questionable Benefit at the End of Life (link to abstract and commentaries) AND Preventive Drugs in the Last Year of Life of Older Adults with Cancer: Is There Room for Deprescribing? (link to abstract and commentary)

 

7 – Diagnosis and treatment of acute alcohol intoxication and alcohol withdrawal syndrome: position paper of the Italian Society on Alcohol – Internal and Emergency Medicine (free PDF)

 

8 – Small Bowel Gastrointestinal Bleeding Diagnosis and Management—A Narrative Review – Frontiers in Surgery (free)

 

9 – Telehealth Has An Awareness Problem – Forbes (free)

 

10 – Optimism is associated with exceptional longevity in 2 epidemiologic cohorts of men and women – Proceedings of the National Academy of Sciences (link to abstract – $ for full-text)

Commentaries: New evidence that optimists live longer – Boston University School of Medicine (free) AND Glass-half-full attitude may help you live past 85, new study finds  – STAT (free) AND Staying optimistic might boost longevity, study shows – UPI (free) AND Reason to be cheerful? ‘Optimists live longer’ study reports – NHS Choices (free)

 


Tue August 27 – 10 Stories of The Day!

27 Aug, 2019 | 02:00h | UTC

 

1 – Management of cardiogenic shock complicating myocardial infarction: an update 2019 – European Heart Journal (free)

Related: Management of cardiogenic shock complicating myocardial infarction – Intensive Care Medicine (free for a limited period) AND AHA Scientific Statement: Contemporary Management of Cardiogenic Shock (free) AND Cardiogenic Shock – Journal of the American Heart Association (free) AND SCAI Clinical Expert Consensus Statement on the Classification of Cardiogenic Shock (free)

 

2 – Why Doctors Still Offer Treatments That May Not Help – The New York Times (10 articles per month are free)

Related: When Evidence Says No, But Doctors Say Yes – ProPublica (free) AND Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals (free) AND 10 Medical Myths We Should Stop Believing. Doctors, Too. – The New York Times (10 articles per month are free)

 

3 – #168 Diabetes Update with Jeff Colburn MD – The Curbsiders Internal Medicine Podcast (free audio and summary)

 

4 – Thoracic ultrasonography: a narrative review – Intensive Care Medicine (free)

Related: Thoracic Ultrasound: What Non-radiologists Need to Know – Current Pulmonology Reports (free) AND Emergency Thoracic US: The Essentials – RadioGraphics (free) AND Incremental value of thoracic ultrasound in intensive care units: Indications, uses, and applications – World Journal of Radiology (free) AND Ultrasound of the Pleurae and Lungs – Ultrasound in Medicine & Biology (free) AND Lung ultrasound: routine practice for the next generation of internists – The Netherlands Journal of Medicine (free PDF)

 

5 – CDC flags one death and nearly 200 cases of lung illnesses in U.S., possibly tied to vaping – Reuters (free)

See also: Patient’s death could be first in US linked to vaping, officials say – The Guardian (free) AND Illinois patient’s death may be first in US tied to vaping – Associated Press (free)

Related: CDC Investigating Severe Pulmonary Disease Cases Among People Who Use E-Cigarettes (free)

 

6 – Vaping impacts blood vessels, even without nicotine – Reuters (free)

Original Article: Acute Effects of Electronic Cigarette Aerosol Inhalation on Vascular Function Detected at Quantitative MRI – Radiology (free)

Related Studies: E-Cigarettes Linked to Increased Risk of Heart Attacks, Coronary Artery Disease and Depression (free abstract and commentaries) AND Association Between Electronic Cigarette Use and Myocardial Infarction (link to abstract and commentaries)

 

7 – Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality – JAMA Internal Medicine (free for a limited period)

Commentary: More plant protein tied to longer life – Reuters (free)

Related Studies: Plant‐Based Diets Are Associated with a Lower Risk of Cardiovascular Disease and All‐Cause Mortality (free) AND Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease (link to abstract and commentaries) AND Cohort Study: Fruit, vegetable, and legume intake, and cardiovascular disease and deaths (link to abstract and commentaries)

 

8 – Assessment and Management of Patients at Risk for Suicide: Synopsis of the 2019 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines – Annals of Internal Medicine (free)

Related Guidelines: Preventing suicide: A community engagement toolkit – World Health Organization (free PDF) AND Preventing suicide in community and custodial settings – National Institute for Health and Care Excellence (free)

 

9 – Treatments for the Prevention and Management of Suicide: A Systematic Review – Annals of Internal Medicine (free)

 

10 – Association of Restless Legs Syndrome With Risk of Suicide and Self-harm – JAMA Network Open (free)

Commentaries: Suicide risk nearly three times as high for those with restless legs syndrome – UPI (free) AND Restless Legs Syndrome Linked to Increased Risk for Self-Harm or Suicide – NEJM Journal Watch (free)

 


Mon August 26 – 10 Stories of The Day!

26 Aug, 2019 | 00:39h | UTC

 

1 – Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study – The Lancet Neurology (free)

Commentaries: Blood pressure control as an intervention to prevent dementia – The Lancet Neurology (free) AND Early blood pressure changes linked to poorer brain health – University College London (free) AND High blood pressure in mid-30s may pose risk to brain health – BBC (free) AND Blood pressure in our 30s and 40s has lasting impact on brain health – Medical News Today (free)

Related Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia (link to abstract and commentaries)

 

2 – Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study – The Lancet (link to abstract – $ for full-text)

 

3 – Early Experience With Transcatheter Mitral Valve Replacement: A Systematic Review – Journal of the American Heart Association (free)

“TMVR was a feasible, less invasive alternative for treating severe mitral regurgitation in patients with high or prohibitive surgical risk”

 

4 – Effects of Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease: A Mendelian Randomization Study – Journal of the American Heart Association (free)

 

5 – Prioritizing Health in a Changing Climate – New England Journal of Medicine (free)

See also: Human Health on an Ailing Planet — Historical Perspectives on Our Future – New England Journal of Medicine (free) AND Interview with Dr. Renee Salas on the effects of climate change on human health and health systems – New England Journal of Medicine (free audio) AND NEJM Collection: Climate Crisis and Health (free articles)

Related: Climate Change — A Health Emergency (free reports and commentaries on the subject)

 

6 – Human Papillomavirus–Attributable Cancers — United States, 2012–2016 – Centers for Disease Control and Prevention (free)

Commentary: Most HPV-linked cancers due to types targeted by 9vHPV vaccine – MedicalXpress (free)

Related: CDC Updates Recommendations for Human Papillomavirus Vaccination for Adults (free)

 

7 – Adult Immunization Update – JAMA (free for a limited period)

See also: Recommended Adult Immunization Schedule for ages 19 years or older – Centers for Disease Control and Prevention (CDC) / Advisory Committee on Immunization Practices (ACIP) (free PDF)

 

8 – Brachytherapy: An overview for clinicians – CA: A Cancer Journal for Clinicians (free)

 

9 – Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis – The BMJ (free)

Commentaries: Interventions for type 2 diabetes successful across the genetic landscape – Massachusetts General Hospital (free) AND Genetics no barrier to dietary modification benefits on type 2 diabetes risk – medwire News (free)

 

10 – Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis – The BMJ (free)

Editorial: Every step you take – The BMJ (free)

Commentaries: “Sit less—move more and more often”: all physical activity is beneficial for longevity – The BMJ Opinion (free) AND ‘Sit less, move more’ may be key advice for living longer – NHS Choices (free) AND Every Little Step Helps – Any Physical Activity Linked to Decreased Mortality – MedicalResearch.com (free)

 


Fri August 23 – 10 Stories of The Day!

23 Aug, 2019 | 08:52h | UTC

 

1 – 2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis – Arthritis Care & Research (free)

News Release: Rheumatology and Spondylitis Organizations Release Updated Treatment Guideline for Axial Spondyloarthritis (free)

Related Guidelines: Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline (free) AND 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis (free) Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force – Annals of Rheumatic Diseases (free) AND 2018 APLAR axial spondyloarthritis treatment recommendations – International Journal of Rheumatic Diseases (free)

 

2 – Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)

Commentaries: 4-Drug Polypill Cuts CV Risk – NEJM Journal Watch (free) AND Four-in-one pill prevents third of heart problems – BBC (free)

Related: Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) AND Perspective: The Polypill and the Long Journey to Major Impact (opinion and reviews on the subject) AND Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care (free commentaries)

 

3 – Association of Smoking Cessation With Subsequent Risk of Cardiovascular Disease – JAMA (free for a limited period)

Commentaries: Smoking Cessation and Reduction of Cardiovascular Disease Risk – JAMA (free) AND Effects of smoking on the heart, blood vessels take at least a decade to fade – UPI (free)

 

4 – AAP works to protect children from e-cigarettes, calls for JUUL to be removed from market – American Academy of Pediatrics (free)

Related (Satirical Post): Vaping Company Denies New Breastmilk-Flavored E-Cigarette Targets Newborn – GomerBlog (free)

See also: Report: Public Health Consequences of E-Cigarettes (free) AND Adolescents’ Use of “Pod Mod” E-Cigarettes — Urgent Concerns – New England Journal of Medicine (free) AND Did Juul Lure Teenagers and Get ‘Customers for Life’? – The New York Times (10 articles per month are free) AND FDA Takes New Steps to Address Epidemic of Youth E-Cigarette Use (free) AND Study: Association of Electronic Cigarette Use With Subsequent Initiation of Tobacco Cigarettes in Youths (free)

 

5 – Development of Exercise as Interception Therapy for Cancer: A Review – JAMA Oncology (free for a limited period)

Related: Clinical Oncology Society of Australia position statement on exercise in cancer care – The Medical Journal of Australia (free PDF) AND The Exercise and Sports Science Australia position statement: Exercise medicine in cancer management – Journal of Science and Medicine in Sport (free)

 

6 – Clinicians’ Guide to Cannabidiol and Hemp Oils – Mayo Clinic Proceedings (free)

Related: Guideline for Prescribing Medical Cannabinoids in Primary Care (free)

 

7 – Redefining Medication Management in Dialysis: A Kidney Pharmacy Quality Pyramid – Kidney Medicine (free)

Related: Drug Management in the Elderly Adult With Chronic Kidney Disease: A Review for the Primary Care Physician – Mayo Clinic Proceedings (free) AND Medication Reconciliation and Therapy Management in Dialysis-Dependent Patients: Need for a Systematic Approach – Clinical Journal of the American Society of Nephrology (free)

 

8 – Alex Nowbar’s journal review, 22 August 2019 – The BMJ Opinion (free)

 

9 – Management of Glucose Control in Noncritically Ill, Hospitalized Patients Receiving Parenteral and/or Enteral Nutrition: A Systematic Review – Journal of Clinical Medicine (free)

Related Guidelines: Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2019 – American Diabetes Association (free) AND In-Hospital Management of Diabetes – Diabetes Canada Clinical Practice Guidelines Expert Committee (free)

Related Reviews: Glucose Management in Hospitalized Patients – American Family Physician (free) AND Update on Glucose Management Among Noncritically Ill Patients Hospitalized on Medical and Surgical Wards – Journal of the Endocrine Society (free)

 

10 – High Prevalence of Celiac Disease Among Screened First-Degree Relatives – Mayo Clinic Proceedings (free for a limited period)

Commentary: Study calls for screening of all first-degree relatives of celiac disease patients – News Medical (free)

 


Thu August 22 – 10 Stories of The Day!

22 Aug, 2019 | 11:07h | UTC

 

1 – Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG – Part 1 with Recommendations on the Epidemiology, Etiology, Prediction, Primary and Secondary Prevention of Preterm Birth – Geburtshilfe und Frauenheilkunde (free)

See also: Part 2 with Recommendations on the Tertiary Prevention of Preterm Birth and the Management of Preterm Premature Rupture of Membranes (free)

Related: Preterm labour and birth – National Institute for Health and Care Excellence (free) AND Practice Bulletin: Management of Preterm Labor – Obstetrics & Gynecology (free) AND Preterm Labor: One Syndrome, Many Causes – Science (free)

 

Parte superior do formulário

Parte inferior do formulário

2 – Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic health records databases – The Lancet (free)

Commentaries: Is it time to include cancer in cardiovascular risk prediction tools? – The Lancet (free) AND Cancer survivors likely to face increase in long-term risk of cardiovascular disease – London School of Hygiene and Tropical Medicine (free)

Related: AHA Statement: Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors (free guidelines) AND Practical Integration of the ASCO Guidelines for Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers (free guidelines)

 

3 – Ambient Particulate Air Pollution and Daily Mortality in 652 Cities – New England Journal of Medicine (free)

Editorial: Do We Really Need Another Time-Series Study of the PM2.5–Mortality Association? (free)

Related: Global burden of disease attributable to ambient air pollution (free) AND WHO Report: 9 out of 10 People Worldwide Breathe Polluted Air (free) AND Death in the Air: Air Pollution Costs Money and Lives – World Bank (free infographic and report)

 

4 – Myocardial Viability and Long-Term Outcomes in Ischemic Cardiomyopathy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: STICH Myocardial Viability at 10 Years: Still No Link With CABG Effects – TCTMD (free) AND Testing for Myocardial Viability in Patients with Ischemic Heart Failure – NEJM Journal Watch (free for a limited period)

 

5 – Less is more: ten reasons for considering to discontinue unproven interventions – Intensive Care Medicine (free)

Related: What should we stop doing in the ICU? – ICU Management & Practice (free) AND “Less is More”: The New paradigm in Critical Care – EMCrit (free)

 

6 – Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit – JAMA Network Open (free)

Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Systematic Review: Effects of Hyperoxia in Acutely Ill Patients (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)

 

7 – The Keto Diet Is Popular, but Is It Good for You? – The New York Times (10 articles per month are free)

Related Consensus Statement: Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE) – Journal of Endocrinological Investigation (free)

 

8 – Presenting Symptoms in Men and Women Diagnosed With Myocardial Infarction Using Sex‐Specific Criteria – Journal of the American Heart Association (free)

Editorial: Closing the Gap on Sex Disparity in Acute Coronary Syndrome: Is It Time to Reconsider Our Definitions of “Typical”? (free)

Commentary: Women more likely to have ‘typical’ heart attack symptoms than men – British Heart Foundation (free)

 

9 – Omega-3, omega-6, and total dietary polyunsaturated fat for prevention and treatment of type 2 diabetes mellitus: systematic review and meta-analysis of randomised controlled trials – The BMJ (free)

Commentaries: The role of nutrition in disease prevention—how we can find better answers? – The BMJ Opinion (free) AND Omega-3 fats have little or no effect on type 2 diabetes – BMJ (free) AND Lack of omega-3 effect on type 2 diabetes confirmed – Medicine Matters (free) AND Fish oil pills ‘no benefit’ for type 2 diabetes – BBC (free)

Related Randomized Trial: Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus (free study and commentaries)

 

10 – Oral antibiotic use and risk of colorectal cancer in the United Kingdom, 1989–2012: a matched case–control study – Gut (free)

Commentaries: Antibiotic use linked to heightened bowel cancer risk – BMJ (free) AND Antibiotics and bowel cancer: Study finds link – Medical News Today (free) AND Oral antibiotic use linked to heightened bowel cancer risk – OnMedica (free)

 


Wed August 21 – 10 Stories of The Day!

21 Aug, 2019 | 08:44h | UTC

 

1 – BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing – US Preventive Services Task Force (free)

Editorials: Broadening Criteria for BRCA1/2 Evaluation: Placing the USPSTF Recommendation in Context – JAMA (free for a limited period) AND Hereditary Cancer Evaluation in 2019—a Rapidly Evolving Landscape – JAMA Oncology (free for a limited period) AND US Preventive Services Task Force Breast Cancer Recommendation Statement on Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer – JAMA Surgery (free for a limited period) AND USPSTF Recommendations for BRCA1 and BRCA2Testing in the Context of a Transformative National Cancer Control Plan – JAMA Network Open (free)

Author Interview: USPSTF Recommendation: Assessment, Counseling, and Testing for BRCA-Related Cancer (free audio)

Commentaries: More women should be assessed for BRCA mutations, new recommendations say – CNN (free) AND Expert panel updates advice on BRCA cancer gene screening – Reuters (free)

 

2 – Clostridioides difficile: diagnosis and treatments – The BMJ (free for a limited period)

Related Guidelines: IDSA Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children (free) AND 2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients – World Journal of Emergency Surgery (free) AND Consensus on the prevention, diagnosis, and treatment of Clostridium difficile infection – Revista de Gastroenterología de México (free) AND The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications (free) AND Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients (free) AND Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children (free)

 

3 – Catheter Ablation for Atrial Fibrillation in 2019 – JAMA (free for a limited period)

Related Randomized Trial: Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation (link to abstract and commentaries)

Related Meta-Analysis: Catheter Ablation for Atrial Fibrillation Improves Outcomes in Heart Failure with Reduced Ejection Fraction (free)

 

4 – Essociation of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis – JAMA (free for a limited period)

Editorial: Thyroid Function Test Abnormalities During Pregnancy (free)

 

5 – Effect of Continuing Olanzapine vs Placebo on Relapse Among Patients With Psychotic Depression in Remission: The STOP-PD II Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Maintenance Treatment for Psychotic Depressive Disorders: Progress and Remaining Challenges (free for a limited period)

 

6 – Why digital medicine depends on interoperability – npj Digital Medicine (free)

 

7 – Do no harm: a roadmap for responsible machine learning for health care – Nature Medicine (free for a limited period)

 

8 – What are children dying from and what can we do about it? – Our World in Data (free)

 

9 – Medicare Part D Spending on Single-Enantiomer Drugs Versus Their Racemic Precursor – Annals of Internal Medicine (free)

Commentary: Prescribing older generics could’ve saved Medicare $17.7B, study finds – Becker’s Hospital Review (free)

Related Study: Potential Savings from Generic Substitution and Therapeutic Interchange of ACE Inhibitors and Angiotensin-II-Receptor Blockers (no abstract – $ for full-text)

 

10 – Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada – JAMA Pediatrics (free)

Editor’s Note: Decision to Publish Study on Maternal Fluoride Exposure During Pregnancy (free)

Editorial: Is Fluoride Potentially Neurotoxic? (free)

Audio Summary: Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada (free)

Commentaries: No proof that a mother’s intake of fluoride in pregnancy affects their child’s IQ – NHS Choices (free) AND Fluoride And IQ? What Is The Link, What This Study Says – Forbes (free) AND Expert reaction to study looking at maternal exposure to fluoride and IQ in children – Science Media Centre (free)

 


Tue August 20 – 10 Stories of The Day!

20 Aug, 2019 | 08:59h | UTC

 

1 – Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association – Circulation (free PDF)

News Release: Prescription omega-3 fatty acid medications effectively lower high triglycerides – American Heart Association (free)

Related: Omega-3 Supplements Do Not Reduce the Risk of Cancer or Cardiovascular Disease (randomized trial and systematic reviews on the subject)

 

2 – New clinical guidelines on the spinal stabilisation of adult trauma patients – consensus and evidence based – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

Related: The Norwegian guidelines for the prehospital management of adult trauma patients with potential spinal injury (free) AND Cervical spine collar clearance in the obtunded adult blunt trauma patient: A systematic review and practice management guideline from the Eastern Association for the Surgery of Trauma (free) AND Prehospital Cervical Spinal Immobilization After Trauma – Neurosurgery (free) AND Pre-Hospital Care Management of a Potential Spinal Cord Injured Patient: A Systematic Review of the Literature and Evidence-Based Guidelines – Journal of Neurotrauma (free) AND Wilderness Medical Society Practice Guidelines for Spine Immobilization in the Austere Environment (free)

 

3 – Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation – Journal of Thrombosis and Haemostasis (free)

Related Reviews: Diagnosis of sepsis‐induced disseminated intravascular coagulation and coagulopathy – Acute Medicine & Surgery (free) AND Sepsis-associated disseminated intravascular coagulation and its differential diagnoses – Journal of Intensive Care (free) AND Advance in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation – Journal of Clinical Medicine (free)

Source: Critical Care Reviews Newsletter

 

4 – Clinical Outcomes After Intensifying Antihypertensive Medication Regimens Among Older Adults at Hospital Discharge – JAMA Internal Medicine (free for a limited period)

Commentary: Intensifying Antihypertensives at Discharge Tied to Adverse Events – NEJM Journal Watch (free)

Related Study: Overtreatment of Blood Pressure Common at Hospital Discharge (free)

 

5 – Outcomes Associated With Clopidogrel-Aspirin Use in Minor Stroke or Transient Ischemic Attack: A Pooled Analysis of Clopidogrel in High-Risk Patients With Acute Non-Disabling Cerebrovascular Events (CHANCE) and Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trials – JAMA Neurology (free for a limited period)

Related Study: The Benefits of Clopidogrel-aspirin Combination after Minor Stroke/TIA occurs Predominantly Within the First 21 Days (free)

Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)

 

6 – News Release: CDC, states investigating severe pulmonary disease among people who use e-cigarettes – Centers for Disease Control and Prevention (free)

Commentaries: More than 120 cases of lung disease in 15 states could be linked to vaping – CNN (free) AND CDC probes lung illnesses linked to e-cigarette use – Reuters (free) AND What’s Behind A Cluster Of Vaping-Related Hospitalizations? – NPR (free) AND CDC Investigating Cases of Severe Lung Disease Tied to Vaping – NEJM Journal Watch (free)

 

7 – Effects of maternal influenza vaccination on adverse birth outcomes: A systematic review and Bayesian meta-analysis – PLOS One (free)

Related Research: Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers (free)

Related ACOG Guideline: Influenza Vaccination During Pregnancy (free)

“maternal influenza vaccination is not associated with harmful effects on birth outcomes. The beneficial effects reported from previous studies on preterm birth, low birth weight, and fetal death could not be confirmed.”

 

8 – Global Incidence of Frailty and Prefrailty Among Community-Dwelling Older Adults: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: The Dynamics of Frailty Among Older Adults – JAMA Network Open (free) AND Frailty is a medical condition, not an inevitable result of aging – Monash University (free)

Related: Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report – Age and Ageing (free) AND A Review of Frailty Syndrome and Its Physical, Cognitive and Emotional Domains in the Elderly – Geriatrics (free) AND Frailty: Identifying elderly patients at high risk of poor outcomes – Canadian Family Physician (free)

 

9 – Early discharge hospital at home – NEJM Catalyst (free)

Related: Interventions to Promote Early Discharge and Avoid Inappropriate Hospital (Re)Admission: A Systematic Review – International Journal of Environmental Research and Public Health (free) AND Early discharge hospital at home – Cochrane Library (free) AND Early discharge ‘hospital-at-home’ gives similar outcomes to in-patient care – NIHR Signal (free)

 

10 – Difficult airway management algorithms: a directed review – Anaesthesia (free)

Related Guidelines: Difficult intubation and extubation in adult anaesthesia – Anaesthesia Critical Care & Pain Medicine (free) AND Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults – British Journal of Anaesthesia (free) AND Practice Guidelines for Management of the Difficult Airway: An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway – Anesthesiology (free) AND The difficult airway with recommendations for management – Part 1 – Difficult tracheal intubation encountered in an unconscious/induced patient – Canadian Journal of Anesthesia (free) AND The difficult airway with recommendations for management – Part 2 – The anticipated difficult airway – Canadian Journal of Anesthesia (free) AND Guidelines for the management of tracheal intubation in critically ill adults – British Journal of Anaesthesia (free) AND S1 guidelines on airway management – German Society of Anesthesiology and Intensive Care Medicine (free)

 


Mon August 19 – 10 Stories of The Day!

19 Aug, 2019 | 08:29h | UTC

 

1 -2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases – Annals of Rheumatic Diseases (free)

 

2 – Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care – Obesity Reviews (free)

Related: Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis – PLOS Medicine (free)

 

3 – Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study – The Lancet (link to abstract – $ for full-text)

Commentaries: ‘Silent’ strokes common after surgery, linked to cognitive decline – McMaster University (free) AND ‘Silent’ strokes after elective surgeries in older adults double their risk of later cognitive decline, study finds – The Globe and Mail (free)

 

4 – Lactate guided resuscitation—nothing is more dangerous than conscientious foolishness – Journal of Thoracic Disease (free PDF)

Related Opinion: The ten pitfalls of lactate clearance in sepsis – Intensive Care Medicine (free)

Related Randomized Trial: Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels in Patients with Septic Shock (free)

 

5 – The Global Prevalence of Anxiety Among Medical Students: A Meta-Analysis – International Journal of Environmental Research and Public Health (free)

Related: Medical student wellbeing – a consensus statement from Australia and New Zealand – BMC Medical Education (free) AND Prevalence of Depression, Depressive Symptoms, and Suicidal Ideation Among Medical Students: A Systematic Review and Meta-Analysis – JAMA (free)

 

6 – Sick hospital workers often expose patients to contagious illness – Reuters (free)

Original Study: Which healthcare workers work with acute respiratory illness? Evidence from Canadian acute-care hospitals during 4 influenza seasons: 2010–2011 to 2013–2014 – Infection Control & Hospital Epidemiology (free)

Related: Working While Sick: A Systematic Review of Infectious Illness Presenteeism (free)

 

7 – Promising new tuberculosis drug pretomanid approved, but will it be affordable? – Médecins Sans Frontières (free)

Original News Release: FDA approves new drug for treatment-resistant forms of tuberculosis that affects the lungs – U.S. Food & Drug Administration (free)

See also: New Drug Could Be Game Changer For Drug-Resistant TB. But A Question Looms – NPR (free) AND Treatment for extreme drug-resistant tuberculosis wins US government approval – Nature (free) AND Scientists Discover New Cure for the Deadliest Strain of Tuberculosis – The New York Times (10 articles per month are free) AND U.S. FDA approves TB Alliance’s treatment for drug-resistant tuberculosis – Reuters (free)

 

8 – Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial – JAMA Network Open (free)

 

9 – Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study – PLOS Medicine (free)

Commentaries: Socially active 60-year-olds face lower dementia risk – University College London (free) AND Social Contact Associated With Lower Dementia Risk – MD Magazine (free)

 

10 – Association Between Electronic Cigarette Use and Marijuana Use Among Adolescents and Young Adults: A Systematic Review and Meta-analysis – JAMA Pediatrics (abstract Only – $ for full-text)

Commentaries: Youth Who Use E-Cigarettes May Be More Likely to Use Marijuana, Study Finds – Psychiatric News Alert (free) AND Teens who vape three times more likely to use marijuana – UPI (free) AND Vaping linked to marijuana use in young people, research says – CNN (free)

 


Fri August 16 – 10 Stories of The Day!

16 Aug, 2019 | 08:23h | UTC

 

1 – Diagnosis and management of metabolic acidosis: guidelines from a French expert panel – Annals of Intensive Care (free)

 

2 – Interdisciplinary consensus on indications for transfemoral transcatheter aortic valve implantation (TF-TAVI) – Clinical Research in Cardiology (free)

Related Guidelines: 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease (free) AND 2017 ESC/EACTS Guidelines for the management of valvular heart disease (free)

 

3 – How doctors in senior leadership roles establish and maintain a positive patient-centred culture – General Medical Council (free PDF)

Summary: How doctors in senior leadership roles establish and maintain a positive patient-centred culture (free)

Commentary: Do You Work in a ‘Diva Subculture’? – Medscape (free registration required)

Related: Healing the Professional Culture of Medicine – Mayo Clinic Proceedings (free) AND Understanding organisational culture for healthcare quality improvement – The BMJ (free)

 

4 – Two weeks versus four weeks of antibiotic therapy after surgical drainage for native joint bacterial arthritis: a prospective, randomised, non-inferiority trial – Annals of Rheumatic Diseases (free)

Commentary: Optimal Duration of Antibiotic Use in Septic Arthritis – NEJM Journal Watch (free for a limited period)

 

5 – Communication Strategies for Sharing Prognostic Information With Patients: Beyond Survival Statistics – JAMA (free for a limited period)

See also: Author Interview (free audio)

 

6 – Resident Physicians are at Increased Risk for Dangerous Driving after Extended-duration Work Shifts: A Systematic Review – Cureus (free)

Source: Hospital Medicine Virtual Journal Club

 

7 – Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ (free)

Related: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)

Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.

 

8 – Essential tremor: diagnosis and management – The BMJ (free for a limited period)

 

9 – Human Papillomavirus Vaccination for Adults: Updated Recommendations of the Advisory Committee on Immunization Practices – Centers for Disease Control and Prevention (free)

Commentaries: CDC Recommends HPV Catch-Up Vaccine in Those 26 and Younger – NEJM Journal Watch (free) AND Confused About Who Should Get the HPV Vaccine, and When? The CDC Has New Recommendations – Time (free)

 

10 – Severe Hypoglycemia Attributable to Intensive Glucose-Lowering Therapy Among US Adults With Diabetes – Mayo Clinic Proceedings (link to abstract – $ for full-text)

Commentary: Too Much of a Good Thing Can Be Dangerous, Finds Researchers Investigating Hypoglycemia – Mayo Clinic (free)

Related Studies: Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries – Journal of General Internal Medicine (free)  AND Rates of Deintensification of Blood Pressure and Glycemic Medication Treatment Based on Levels of Control and Life Expectancy in Older Patients With Diabetes Mellitus – JAMA Internal Medicine (free)

 


Thu August 15 – 10 Stories of The Day!

15 Aug, 2019 | 10:30h | UTC

 

1 – Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention – Neurology (fee PDF)

See also: Practice guideline update summary: Acute treatment of migraine in children and adolescents – Neurology (free PDF)

Commentaries: AAN issues guidelines for treatment of migraine in children and teens – American Academy of Neurology (free) AND Guidelines Updated on Preventing and Treating Migraine in Children and Teens – NEJM Journal Watch (free)

 

2 – American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Opioid Minimization in Opioid-Naïve Patients – Anesthesia & Analgesia (free)

Related Position Statements on Perioperative Opioid Therapy: American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Management of Patients on Preoperative Opioid Therapy (free) AND American Society for Enhanced Recovery and Perioperative Quality Initiative-4 Joint Consensus Statement on Persistent Postoperative Opioid Use: Definition, Incidence, Risk Factors, and Health Care System Initiatives (free)

See also: American Society of Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statements (free) AND Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 

3 – Optimal Combination of Compression Rate and Depth During Cardiopulmonary Resuscitation for Functionally Favorable Survival – JAMA Cardiology (free for a limited period)

Commentaries: Push Hard, Push Fast, Do Not Stop—Optimal Chest Compression Rate and Depth – JAMA Cardiology (free for a limited period) AND Study Details Optimal CPR Speed, Depth – NEJM Journal Watch (free)

Related: Performing CPR? Humming the Macarena Could Help (free)

 

4 – Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk – JAMA (free for a limited period)

Editorial: Gluten and Celiac Disease Risk: Is It Just a Matter of Quantity? (free for a limited period)

Commentaries: Association between coeliac disease risk and gluten intake confirmed – Lund University (free) High Gluten Diet Adds to Risk of Celiac Disease In Genetically Predisposed Children – MedicalResearch.com (free) AND Eating more gluten early in life is tied to children’s higher risk of celiac disease, a study says – CNN (free)

 

5 – Imaging of Pulmonary Hypertension: Pictorial Essay – Chest (free)

Related Guidelines: Therapy for Pulmonary Arterial Hypertension in Adults 2018: Update of the CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free) AND 2018 TSOC guideline focused update on diagnosis and treatment of pulmonary arterial hypertension – Journal of the Formosan Medical Association (free)

 

6 – Key concepts for making informed choices – Nature (free)

 

7 – An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis – Nature Medicine (free for a limited period)

 

8 – Perspective: Healthcare Needs AI, AI Needs Causality – Forbes (free)

 

9 – Guidelines for the management of common congenital heart diseases: A consensus statement on indications and timing of intervention – Indian Heart Journal (free)

 

10 – Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Don’t Use More Than 400 mg of Ibuprofen for Pain Control – NEJM Journal Watch (free for a limited period)

 


Wed August 14 – 10 Stories of The Day!

14 Aug, 2019 | 10:46h | UTC

 

1 – Two Ebola drugs show promise amid ongoing outbreak – Nature (free)

See also: Ebola drugs show ‘90% survival rate’ in breakthrough trial – BBC (free) AND AND 2 Experimental Ebola Drugs Saved Lives In Congo Outbreak – NPR (free) AND A Cure for Ebola? Two New Treatments Prove Highly Effective in Congo – The New York Times (10 articles per month are free)

 

2 – Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia – JAMA (free for a limited period)

Related Research: Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions – JAMA (free for a limited period)

Editorial: Blood Pressure, Brain Volume and White Matter Hyperintensities, and Dementia Risk (free for a limited period)

Video Summary: Hypertension and Dementia (free)

Commentary: Expert reaction to two studies looking at blood pressure and dementia – Science Media Centre (free)

 

3 – Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function – JAMA (free for a limited period)

Video Abstract: Ambient Air Pollution and Change in Emphysema and Lung Function (free)

Commentaries: Air Pollution May Be As Harmful To Your Lungs As Smoking Cigarettes, Study Finds – NPR (free) AND Study finds link between long-term exposure to air pollution and emphysema – NIH News Releases (free)

 

4 – Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)

Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)

Source: NEJM Journal Watch ($)

 

5 – Update on the contraceptive contraindications – Journal of Gynecology Obstetrics and Human Reproduction (free)

Related Guidelines: WHO Medical eligibility criteria for contraceptive use (free PDF) AND US Medical Eligibility Criteria for Contraceptive Use (free) AND UK Medical Eligibility Criteria for Contraceptive Use (free)

 

6 – Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review – JAMA (free for a limited period)

 

7 – Mechanisms for hemodynamic instability related to renal replacement therapy: a narrative review – Intensive Care Medicine (free)

Related: Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review – Critical Care (free)

 

8 – The entire human brain in ‘unprecedented’ detail, thanks to powerful MRI – STAT (free)

 

9 – Draft Recommendation Statement: Screening for Illicit Drug Use, Including Nonmedical Use of Prescription Drugs: Screening – U.S. Preventive Services Task Force (free)

Commentaries: For the first time, U.S. panel recommends screening adults for illicit drug use – STAT (free) AND Screen All Adult Patients for Drug Abuse, National Panel Urges – The New York Times (10 articles per month are free) AND

 

10 – Roles of cyberbullying, sleep, and physical activity in mediating the effects of social media use on mental health and wellbeing among young people in England: a secondary analysis of longitudinal data – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

Commentaries: Social media use may harm teens’ mental health by disrupting positive activities, study says – CNN (free) AND Social-media use ‘disrupting teen sleep and exercise’ – BBC (free) AND Expert reaction to study on social media use and the role of cyberbullying, sleep and physical activity in the wellbeing in young people – Science Media Centre (free) AND Social Media’s Ill Effects in Teen Girls: 3 Factors Play Large Role – NEJM Journal Watch (free)

 


Tue August 13 – 10 Stories of The Day!

13 Aug, 2019 | 08:02h | UTC

 

1 – Diabetes Technology: Review of the 2019 American Diabetes Association Standards of Medical Care in Diabetes – Annals of Internal Medicine (free)

Original Guideline: ADA 2019 Standards of Medical Care in Diabetes (free)

 

2 – Perfusion Assessment in Critical Limb Ischemia: Principles for Understanding and the Development of Evidence and Evaluation of Devices: A Scientific Statement From the American Heart Association – Circulation (free)

News Release: Evaluating blood flow is key to early diagnosis and treatment for people with critical limb ischemia – American Heart Association (free)

Commentary: AHA Outlines Diagnosis, Treatment Options for Underrecognized Critical Limb Ischemia – TCTMD (free)

 

3 – Adjunctive Corticosteroid Treatment in Septic Shock – Anesthesiology (free)

Related Guideline: Corticosteroid therapy for sepsis: a clinical practice guideline – The BMJ (free)

Related Meta-Analysis: Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract) AND Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis – Critical Care Medicine (free) AND Association of Corticosteroid Treatment With Outcomes in Adult Patients With Sepsis: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Source: Critical Care Reviews Newsletter

 

4 – #165 Things We Do For No Reason™ Part 2 – The Curbsiders Internal Medicine Podcast (free audio and summary)

See also: Part 1: #109: Things We Do For No Reason: A High Value Episode – The Curbsiders internal Medicine Podcast (free audio and summary)

Related Series: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine (free articles)

“Discover common practices that persist in the hospital wards despite no proven benefit!”

 

5 – Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study – The Lancet Diabetes & Endocrinology (link to abstract and commentaries)

Commentaries: Different diabetes phenotypes associated with varying prevalence of complications – ACP Diabetes (free) AND Cluster analysis may help to predict diabetic complications – medwire News (free)

Related Study: Novel subgroups of adult-onset diabetes and their association with outcomes (link to abstract and commentaries)

 

6 – Long-term adverse events after sleeve gastrectomy or gastric bypass: a 7-year nationwide, observational, population-based, cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentary: Death Risk Drops After Bariatric Surgery in Obese Patients – MedPage Today (free registration required)

Related Research: Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)

 

7 – When less is more in the active management of elevated body temperature of ICU patients – Intensive Care Medicine (free PDF)

Related: Fever control in critically ill adults. An individual patient data meta-analysis of randomised controlled trials – Intensive Care Medicine (free)

 

8 – ‘War on cancer’ metaphors may do harm, research shows – The Guardian (free)

Related: Why cancer is not a war, fight, or battle – CNN (free) AND He’s a Fighter – The Atlantic (free) AND Cancer cliches to avoid: I’m not ‘brave’ – BBC (free)

 

9 – Association of Hearing Loss With Dementia – JAMA Network Open (free)

Commentary: Middle-age hearing loss linked to dementia – Reuters (free)

Related Meta-Analysis: Association of Age-Related Hearing Loss With Cognitive Function (free study and commentaries)

 

10 – Management of ovarian cancer risk in women with BRCA1/2 pathogenic variants – Canadian Medical Association Journal (free for a limited period)

Commentaries: Review Offers Guidance on Managing Ovarian Cancer Risk in BRCA Mutation Carriers – NEJM Journal Watch (free) AND Managing ovarian cancer risk in women with BRCA1/2 genetic variants – Joule Inc. (free)

Related: USPSTF Draft Statement: BRCA-Related Cancer Risk Assessment, Genetic Counseling, and Genetic Testing (free draft statement and commentaries) AND Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening (free) AND Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers (free study and commentaries)

 


Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.