TOP 10 Medical News Stories

 

1 – Tuberculosis – National Institute for Health and Care Excellence (free)

Related: WHO Guidelines on Tuberculosis Infection Prevention and Control (free guidelines)

 

2 – The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis – The Lancet (free registration required)

Related Articles: Management of drug-resistant tuberculosis – The Lancet (free registration required) AND Challenges and controversies in childhood tuberculosis – The Lancet (free)

Editorial: Tuberculosis needs accelerated and continued attention (free)

Related: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free) AND Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment (free)

 

3 – Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial – The Lancet (free)

Commentaries: HEALTH for heavy menstrual bleeding: real-world implications – The Lancet (free) AND Heavy menstrual bleeding: Keyhole hysterectomy technique ‘more effective’ – BBC (free)

 

4 – Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials – Science Translational Medicine (free for a limited period)

Commentaries: Cancer drugs don’t always work as intended, researchers warn – Cold Spring Harbor Laboratory (free) AND Why Aren’t Cancer Drugs Better? The Targets Might Be Wrong – The New York Times (10 articles per month are free)

 

5 – Supercooling Extends Preservation Time of Human Livers – Nature Biotechnology (free)

Commentaries: Scientists triple storage time of human donor livers – NIH News Releases (free) AND ‘Supercool’ method triples organ survival – BBC (free) AND A Human Liver Can Be Cooled to –4 Degrees Celsius and Survive – The Atlantic (free)

 

6 – Combined lifestyle factors and risk of incident type 2 diabetes and prognosis among individuals with type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies – Diabetologia (free)

Commentary: Diabetes Risk Plummets by 75% When Multiple Risk Factors Tackled – Medscape (free registration required)

 

7 – Chest Radiograph Signs Suggestive of Pericardial Disease – American College of Cardiology (free)

 

8 – Vaccines for Health Care Personnel – Mayo Clinic Proceedings (free)

Related: Immunization of Health-Care Personnel: Recommendations of the Advisory Committee on Immunization Practices (ACIP) – Centers for Disease Control and Prevention (free) AND Vaccination of healthcare workers: A review – Human Vaccines & Immunotherapeutics (free)

 

9 – Pneumococcal Disease: A Systematic Review of Health Utilities, Resource Use, Costs, and Economic Evaluations of Interventions – Value in Health (free)

Related: Pneumococcal infection in adults: burden of disease – Clinical Microbiology and Infection (free) AND The remaining challenges of pneumococcal disease in adults – European Respiratory Review (free)

 

10 – Prospective Evaluation of Maternal Sleep Position Through 30 Weeks of Gestation and Adverse Pregnancy Outcomes – Obstetrics & Gynecology (free)

Commentary: Sleeping on back may not lead to worse pregnancy outcomes – Reuters (free)

 


 

1 – Enhanced Recovery After Surgery (ERAS) Guidelines for Perioperative Care in Cesarean Delivery – American Journal of Obstetrics & Gynecology (free articles)

Part I: Guidelines for Antenatal and Preoperative care in Cesarean Delivery: Enhanced Recovery After Surgery Society Recommendations

Part II: Guidelines for intraoperative care in cesarean delivery: Enhanced Recovery After Surgery Society Recommendations

Part III: Guidelines for postoperative care in cesarean delivery: Enhanced Recovery After Surgery (ERAS) Society recommendations

Related: Guidelines for perioperative care in gynecologic/oncology: Enhanced Recovery After Surgery (ERAS) Society recommendations—2019 update – International Journal of Gynecological Cancer (free) AND Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 

2 – A Randomized Trial of Prenatal n−3 Fatty Acid Supplementation and Preterm Delivery – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Fish oil study fails to show reduction in premature babies – Reuters (free)

 

3 – Screening mammography outcomes: risk of breast cancer and mortality by comorbidity score and age – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)

Commentaries: More evidence screening mammograms not needed for many older women – Reuters (free) AND Mammography unlikely to benefit older women with chronic illnesses – Georgetown University Medical Center (free)

 

4 – Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth – JAMA Psychiatry (link to abstract – $ for full-text)

Author Interview: Associations Between Social Media Time and Internalizing and Externalizing Problems Among US Youth (free audio)

Commentaries: Social Media Use by Adolescents Linked to Internalizing Behaviors – Johns Hopkins Bloomberg School of Public Health (free) AND More Social Media Use Linked to More Depression and Anxiety in Teens – NEJM Journal Watch (free) AND Expert reaction to study looking at social media and adolescent mental health – Science Media Centre (free)

Related: Association of Screen Time and Depression in Adolescence (links to abstract and commentaries) AND The Adverse Effects of Social Media use on Young People’s Mental Health May be Caused by Exposure to Cyberbullying, Loss of Sleep, and Reduced Physical Activity (links to abstract and commentaries) AND Research: This Is Your Brain Off Facebook (free) AND Cohort Study: Social Media Use and Adolescent Mental Health (free) AND Supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn (free articles)

 

5 – Respiratory syncytial virus infection in adults – The BMJ (free for a limited period)

Related Reviews: Respiratory Syncytial Virus and Other Non-influenza Respiratory Viruses in Older Adults – Infectious Disease Clinics of North America (free) AND Respiratory Syncytial Virus infection: an illness for all ages – Clinics in Chest Medicine (free)

 

6 – Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial – The BMJ (free)

 

7 – Gluten Does Not Induce Gastrointestinal Symptoms in Healthy Volunteers: A Double-Blind Randomized Placebo Trial – Gastroenterology (free for a limited period)

Commentaries: Will Science Sway Beliefs About Gluten? – Gastroenterology (free for a limited period) AND One of The Most Rigorous Experiments We Have Shows Gluten Isn’t Bad For Healthy People – Science Alert (free) AND Quick Take: Gluten does not induce gastrointestinal symptoms in healthy volunteers – 2 Minute Medicine (free)

 

8 – How many premature deaths from pesticide suicide have occurred since the agricultural Green Revolution? – Clinical Toxicology (free)

Commentaries: Scale of suicides by pesticide poisoning revealed – University of Edinburgh (free) AND 15 million people worldwide may have died by suicide with pesticides – UPI (free)

Related: Suicide in the World: WHO Global Health Estimates (free report and commentaries) AND Preventing Suicide: A resource for pesticide registrars and regulators – World Health Organization (free PDF)

 

9 – Prevalence and Predictability of Low-Yield Inpatient Laboratory Diagnostic Tests – JAMA Network Open (free)

Commentary: Is that blood test really necessary? AI could help decide – Stanford Medicine (free)

 

10 – Opinion: Ban Flavored E-Cigarettes to Protect Our Children – The New York Times (10 articles per month are free)

Related: Trump administration prepares to ban flavored e-cigarettes – STAT (free) AND ATS Responds to FDA’s Promise of Future Action on Flavored E-Cigarettes – American Thoracic Society (free)

 


 

1 – Suicide in the World: Global Health Estimates – World Health Organization (free PDF)

News Release: Suicide: one person dies every 40 seconds – World Health Organization (free)

Commentaries: One person dies by suicide every 40 seconds: new UN health agency report – UN News (free) Suicide kills one person every 40 seconds, says WHO – Reuters (free) AND One person dies every 40 seconds from suicide, WHO says – CNN (free)

 

2 – The Occupational Burden of Nonmalignant Respiratory Diseases. An Official American Thoracic Society and European Respiratory Society Statement – American Journal of Respiratory and Critical Care Medicine (free)

Commentaries: Occupational hazards account for more than one in ten people with range of lung diseases – American Thoracic Society (free) AND Respiratory Hazards at Work Linked to Disease for 1 in 10 People Worldwide – AJMC (free)

 

3 – Draft Recommendation Statement: Screening for Cognitive Impairment in Older Adults – U.S. Preventive Services Task Force (free)

Commentary: USPSTF: Evidence Lacking for Cognitive Screening in Older Adults – Physician’s Briefing (free)

 

4 – Effect of Corticosteroid-Sparing Treatment With Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients With Uveitis: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: Antimetabolite Therapy for Uveitis: Methotrexate or Mycophenolate? – JAMA Ophthalmology (free for a limited period) AND Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial – NIH News Releases (free)

 

5- Scientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy: A Review – JAMA Neurology (free for a limited period)

Related: Diagnosis and management of sensory polyneuropathy – The BMJ (free) AND Small‐fiber neuropathy: Expanding the clinical pain universe – Journal of the Peripheral Nervous System (free) AND Small-fiber neuropathy definition, diagnosis, and treatment – Neurological Sciences (free)

 

6 – Oral Fluoroquinolones and Risk of Mitral and Aortic Regurgitation – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Fluoroquinolones and Cardiac Valve Regurgitation Risk – American College of Cardiology (free) AND Commonly used antibiotics may lead to heart problems – University of British Columbia (free)

Related: Committee Recommends New Restrictions on the use of Fluoroquinolones (free report and commentaries) AND FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions (free statement and commentaries) AND FDA Warns About Increased Risk of Aortic Dissection and Ruptures of Aortic Aneurism with Fluoroquinolones (free report and commentaries) AND Fluoroquinolone use and serious arrhythmias: A nationwide case-crossover study – Resuscitation (link to abstract – $ for full-text)

 

7 – Ann Robinson’s journal review, 10 September 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 

8 – Hypertensive Crisis: Pearls and Pitfalls for the ED Physician – emDocs (free)

Related: ESC Council on hypertension position document on the management of hypertensive emergencies – European Heart Journal – Cardiovascular Pharmacotherapy (free) AND 7th Brazilian Guideline of Arterial Hypertension: Chapter 14 – Hypertensive Crisis – Arquivos Brasileiros de Cardiologia (free) AND Focused Update on Pharmacologic Management of Hypertensive Emergencies – Current Hypertension Reports (free)

 

9 – WHO To Revisit Guidelines On Ebola Survivors’ Care; Study Finds 5-fold Higher Mortality – Health Policy Watch (free)

Original Study: Subsequent mortality in survivors of Ebola virus disease in Guinea: a nationwide retrospective cohort study – The Lancet Infectious Diseases (free for a limited period)

See also: Mortality rates in Ebola survivors after hospital discharge could be five times higher compared with the general population – London School of Hygiene & Tropical Medicine (free)

 

10 – Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis – Anesthesia & Analgesia (free)

Infographic: Shiver Me Timbers: Magnesium and Postoperative Shivering (free)

Source: EvidenceAlerts

 


 

1 – Canadian guideline for Parkinson disease – Canadian Medical Association Journal (free)

Related: Parkinson’s disease in adults – National Institute for Health and Care Excellence (NICE) Guideline (free) AND Choosing Wisely: five recommendations related to tests, treatments, and procedures at risk of inappropriateness in the cure of Parkinson’s disease (LIMPE-DISMOV Academy) – Neurological Sciences (free)

 

2 – Latin American consensus on uncomplicated recurrent urinary tract infection – International Urogynecology Journal (free)

Related Guideline: AUA/CUA/SUFU Guideline: Recurrent Uncomplicated Urinary Tract Infections in Women (free article and commentary)

 

3 – 2019 Update on Medical Overuse: A Review – JAMA Internal Medicine (free for a limited period)

 

4 – Effectiveness of Behaviorally Designed Gamification Interventions With Social Incentives for Increasing Physical Activity Among Overweight and Obese Adults Across the United States: The STEP UP Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentaries: Using a wearable device to exercise more? Add competition to improve results – University of Pennsylvania (free) AND Tracking your exercise more effective with competition, study says – CNN (free)

 

5 – #171 Lupus in Primary Care with Beth Jonas MD – The Curbsiders Internal Medicine Podcast (free audio and summary)

Related: 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus – Arthritis & Rheumatology (free) AND New EULAR Recommendations for the Management of Systemic Lupus Erythematosus (free guidelines) AND Systemic Lupus Erythematosus in Primary Care: An Update and Practical Messages for the General Practitioner – Frontiers in Medicine (free)

See also: Episode List

 

6 – Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management – Gut (free)

Related Review: Lactose Intolerance, Dairy Avoidance, and Treatment Options – Nutrients (free)

 

7 – Clinical Practice Guidelines for Childbearing Female Candidates for Bariatric Surgery, Pregnancy, and Post-partum Management After Bariatric Surgery – Obesity Surgery (free)

Related: Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care – Obesity Reviews (free) AND Fertility, Pregnancy and Lactation After Bariatric Surgery – a Consensus Statement from the OEGGG – Geburtshilfe und Frauenheilkunde (free) AND Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis – PLOS Medicine (free) AND Nutrition in Pregnancy Following Bariatric Surgery – Nutrients (free) AND Pregnancy after bariatric surgery: a narrative literature review and discussion of impact on pregnancy management and outcome – BMC Pregnancy and Childbirth (free)

 

8 – Malaria eradication within a generation: ambitious, achievable, and necessary – The Lancet (free registration required)

Homepage: The Lancet Commission on Malaria Eradication (free article and commentaries – registration required)

Commentaries: Malaria can and should be eradicated within a generation, declare global health experts – The Lancet (free) AND Malaria can be eradicated by 2050, say global experts – Reuters (free) AND Defeat malaria in a generation – here’s how – BBC (free) AND It’s ‘Ambitious’ — But Possible — to Eradicate Malaria by 2050, According to a Landmark Report – TIME (free)

 

9 – Short Review: Management of Staphylococcus aureus bacteremia in adults – Canadian Medical Association Journal (free for a limited period)

Related: Clinical Management of Staphylococcus aureus Bacteremia – JAMA (free) AND Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children (free)

 

10 – Anticoagulation After Surgical or Transcatheter Bioprosthetic Aortic Valve Replacement – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Anticoagulation After Bioprosthetic Valve Replacement or TAVR – American College of Cardiology (free) AND Anticoagulation May Be Safe After Bioprosthetic Aortic Valve Replacement – Cardiology Advisor (free) AND Oral Anticoagulation Post-AVR Safe but Not Routinely Needed: PARTNER II – TCTMD (free)

 


 

1 – Criteria for Critical Care Infants and Children: PICU Admission, Discharge, and Triage Practice Statement and Levels of Care Guidance – Pediatric Critical Care Medicine (free)

Executive Summary: Criteria for Critical Care of Infants and Children: PICU Admission, Discharge, and Triage Practice Statement and Levels of Care Guidance – Pediatrics (free)

Commentaries: Critical Care for Infants and Children – Updated Guidance and Practice Statement Released – American Academy of Pediatrics (free) AND Updated recommendations, levels of care categorized for pediatric ICUs – MedicalXpress (free) AND ‘Explosive’ growth in PICUs prompt updated policy in levels, practice of critical care – AAP News (free)

 

2 – Physical activity guidelines: UK Chief Medical Officers’ report (free PDF)

News Release: New physical activity guidelines issued by UK Chief Medical Officers (free)

Commentaries: UK CMOs: When it comes to physical activity some is good, but more is better – The BMJ Opinion (free) AND Strengthen muscles as well as heart to stay fit and healthy, say top doctors – BBC (free) AND No such thing as too little exercise, says Chief Medical Officer, as ten minute minimum is scrapped – The Telegraph (free)

Related: ACSM Scientific Pronouncements: Physical Activity Guidelines for Americans (free)

 

3 – Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial – The Lancet (free)

Commentary: Long-term cardiovascular health after stopping pre-eclampsia – The Lancet (free)

 

4 – Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin — Preliminary Report – New England Journal of Medicine (free)

Editorial: Vaping-Induced Lung Injury (free)

Related: Imaging of Vaping-Associated Lung Disease – New England Journal of Medicine (free) AND Pulmonary Lipid-Laden Macrophages and Vaping – New England Journal of Medicine (free) AND Severe Pulmonary Disease Associated with Electronic-Cigarette–Product Use — Interim Guidance – Centers for Disease Control and Prevention (free)

Commentaries: CDC Says Number Of Possible Cases Of Vaping-Related Lung Illness Has Doubled – NPR (free) AND Cases of Vaping-Related Lung Illness Surge, Health Officials Say – The New York Times (10 articles per month are free) AND Pneumonia cases linked to vaping are still rising. And federal officials don’t know what’s causing them – STAT (free)

 

5 – Reporting and Interpretation of Randomized Clinical Trials – JAMA (free)

 

6 – What Is Known About Candida auris – JAMA (free for a limited period)

Related: Global Epidemiology of Emerging Candida Auris (reviews and commentaries on the subject)

 

7 – A systematic review of clinical guidelines on the management of acute, community-acquired CNS infections – BMC Medicine (free)

Related: The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults (free) AND ESCMID guideline: diagnosis and treatment of acute bacterial meningitis (free) AND Meningitis (bacterial) and meningococcal septicaemia in under 16s: recognition, diagnosis and management – National Institute for Health and Care Excellence (free) AND Management of suspected viral encephalitis in adults – Association of British Neurologists and British Infection Association National Guidelines (free) AND Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines (free)

 

8 – An evidence‐based approach to developing low‐carbohydrate diets for type 2 diabetes management: A systematic review of interventions and methods – Diabetes, Obesity and Metabolism (free)

Source: EvidenceAlerts

 

9 – Assessment and Treatment of Patients with Type 2 Myocardial Infarction and Acute Non-Ischemic Myocardial Injury – Circulation (free PDF)

Related Reviews: A systematic review on the triggers and clinical features of type 2 myocardial infarction – Clinical Cardiology (free) AND Type 2 Myocardial Infarction: An Evolving Entity – Circulation Journal (free)

 

10 – Occupational Cardiology Series: Cardiovascular Assessment of Aircrew and Other High-hazard Employees – European Heart Journal (free articles)

– An Introduction to Occupational Cardiology: Cardiovascular assessment of aircrew and other high-hazard employees. The first article of the series

– Assessment of clinical and occupational cardiovascular risk: This second article in the occupational cardiology series discusses risk for the individual worker, the remainder of the workforce and the public in high-hazard occupations

– Electrophysiologic assessment of aircrew and other high-hazard employees: This third article in the occupational cardiology series focusses on the assessment of arrhythmias in high-hazard employees and how, not all arrhythmias prevent employment

– ECG interpretation: Interpretation of the ECG in young, fit, asymptomatic individuals undertaking high-hazard occupations is the topic of the fourth article in the occupational cardiology series

 


 

1 – Twin and triplet pregnancy – National Institute for Health and Care Excellence (free)

 

2 – Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation – Cochrane Library (free)

Summary: Antiarrhythmics for maintaining sinus rhythm (normal heartbeat) after reversing atrial fibrillation (correcting an irregular heartbeat) – Cochrane Library (free)

 

3 – Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: QoL Better With Laser Ablation, Surgery for Varicose Veins – Drugs.com (free) AND Laser and Surgery Rule for Varicose Veins – MedPage Today (free registration required)

 

4 – Risk Factors and Outcomes Associated With Treatment of Asymptomatic Bacteriuria in Hospitalized Patients – JAMA Internal Medicine (free for a limited period)

Commentary: Asymptomatic Bacteriuria Often Inappropriately Treated With Antibiotics – Medscape (free registration required)

 

5 – American Society for Clinical Pathology: Thirty Things Physicians and Patients Should Question – Choosing Wisely (free)

Commentary: “Choosing Wisely” Calls Out Inappropriate Testing in Patients with Diarrhea or Hepatitis C – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

6 – Ann Robinson’s journal review, 5 September 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 

7 – HbA1c level as a risk factor for retinopathy and nephropathy in children and adults with type 1 diabetes: Swedish population based cohort study – The BMJ (free)

Commentaries: Microvascular benefits of lowest HbA1c target in type 1 diabetes questioned – Medwire News (free) AND How blood sugar levels affect risks in type 1 diabetes – University of Gothenburg (free) AND HbA1c levels of 6.5-7.0 percent may be optimal for adults and children with T1D – Univadis (free registration required)

 

8 – Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study – The BMJ (free)

Editorial: Vegetarian diets and health (free)

Commentaries: Vegetarian Diet Linked to Lower Heart Disease, But Higher Stroke Risks – NEJM Journal Watch (free) AND Vegetarians and pescatarians have lower risk of CHD – OnMedica (free) AND Expert reaction to study on meat-eating, fish-eating and vegetarian diets and risk of heart disease and stroke – Science Media Centre (free)

 

9 – Designing better sugary drink taxes – Science (link to abstract – $ for full-text)

News Release: Taxing Sweetened Drinks by the Amount of Sugar Could Cut Obesity & Boost Economic Gains – NYU (free) AND Experts Say Tax the Sugar—Not the Size—Of Drinks for Healthier Outcomes – AAAS (free) AND A New Soda Tax Strategy Directly Addresses the Real Cost of Sugar – Inverse (free)

Related: Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake (free study and resources on the subject)

 

10 – Potential impact on prevalence of obesity in the UK of a 20% price increase in high sugar snacks: modelling study – The BMJ (free)

Editorial: Taxing confectionery, biscuits, and cakes to control obesity (free) AND

Commentaries: Snack tax may be more effective than a sugary drink tax to tackle obesity – The BMJ (free) AND What next for fiscal interventions to prevent obesity? – The BMJ Opinion (free) AND Taxing sugary foods would cut prevalence of obesity – OnMedica (free) AND Snack tax may be more effective than a sugary drink tax to tackle obesity – London School of Hygiene & Tropical Medicine (free)

Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND  The Lancet taskforce on NCDs and economics (free series and commentaries) To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Reducing cardiovascular disease burden through targeted dietary policies (free study and commentaries) AND Fiscal policies for the prevention of diseases (free study and commentary) AND The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities (free)

 


 

1 – Report: Essential Nutrition Actions: mainstreaming nutrition throughout the life course – World Health Organization (free PDF)

News Release: Stronger focus on nutrition within health services could save 3.7 million lives by 2025 – World Health Organization (free)

Commentaries: Healthier Diets Key To Reducing Obesity And NCDs: Says New WHO Report – Health Policy Watch (free) AND 3.7 million lives could be saved by 2025 if health services ramp up nutrition actions: WHO – UN News (free)

 

2 – Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea – JAMA Network Open (free)

 

3 – N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Respiratory Protection of Health Care Personnel to Prevent Respiratory Viral Transmission (free for a limited period)

Commentaries: Outpatient study finds masks, respirators equally protective – CIDRAP (free) AND Surgical masks as good as respirators for flu and respiratory virus protection – UT Southwestern Medical Center (free)

 

4 – Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Quick Take: Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL) – 2 Minute Medicine (free)

 

5 – Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF) AND Journal Citation in Prehospital Emergency Care (free)

 

6 – Vaping appears to be making hundreds of people sick. No one knows exactly why. – Vox (free)

Related: CDC Flags One Death and Nearly 200 Cases of Lung Illnesses in U.S., Possibly Tied to Vaping (free) AND Another Patient Has Died From Lung Disease After Vaping – The New York Times (10 articles per month are free)

 

7 – Artificial intelligence in medicine raises legal and ethical concerns – The Conversation (free)

Related: Artificial Intelligence Is Infiltrating Medicine — But Is It Ethical? – Forbes (free) AND Artificial Intelligence in Health Care – AMA Journal of Ethics (free articles)

 

8 – Pharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library (free)

Summary: Medicines to treat delirium in critically ill adult patients – Cochrane Library (free)

Related Systematic Reviews: Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free) AND Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 

9 – Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)

Related: USPSTF Recommendation Statement: Medication Use to Reduce Risk of Breast Cancer (free)

 

10 – Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease – JAMA (free for a limited period)

Commentary: Sustained drop in cholesterol and blood pressure reduces lifetime risk of heart, circulatory diseases – News Medical (free)

 


 

1 – Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study – The Lancet (free until Sept 10 – registration required)

Related Study: Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study – The Lancet (free until Sept 10 – registration required)

Commentaries: Cancer now leading cause of death in high-income countries — while heart disease burden persists in low-income and middle-income countries – The Lancet (free) AND Cardiovascular Disease Leading Cause of Death World-Wide, but Cancer Rising Cause in Rich Countries: Study – McMaster University (free) AND Cancer ‘biggest middle-age killer in rich nations’ – BBC (free) AND Cancer overtakes heart disease as biggest rich-world killer – Reuters (free) AND Cancer now tops heart disease as the No. 1 cause of death in these countries – CNN (free)

 

2 – Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Recommendation Summary: Medication Use to Reduce Risk of Breast Cancer (free)

Editorials: Medications to Reduce Breast Cancer Risk: Promise and Limitations (free for a limited period) AND Breast Cancer Chemoprevention—Can We Make a Case for Precision Medicine? (free for a limited period)

Evidence Report and Systematic Review: Medication Use for the Risk Reduction of Primary Breast Cancer in Women – US Preventive Services Task Force (free)

Author Interview: USPSTF Recommendation: Medication Use to Reduce Risk of Breast Cancer (free audio)

Commentaries: Medication can lower some women’s risk of breast cancer – Reuters (free) AND USPSTF: Aromatase Inhibitors Recommended to Help Prevent Breast Cancer – NEJM Journal Watch (free)

 

3 – British Heart Rhythm Society Clinical Practice Guidelines on the Management of Patients Developing QT Prolongation on Antipsychotic Medication – Arrhythmia & Electrophysiology Review (free)

 

4 – How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) – European Heart Journal (free)

 

5 – Resistant Hypertension Updated Guidelines – Current Cardiology Reports (free)

Related: AHA Guideline: Resistant Hypertension (free) AND 7th Brazilian Guideline of Arterial Hypertension: Chapter 13 – Resistant Arterial Hypertension (free)

 

6 – What Statistics Can and Can’t Tell Us About Ourselves – The New Yorker (free)

 

7 – News Release: Oxygen is neither beneficial nor harmful in patients with acute coronary syndrome – European Society of Cardiology (free)

Commentary: Supplemental Oxygen Fails Once Again in ACS Patients: NZOTACS – TCTMD (free)

Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Systematic Review: Effects of Hyperoxia in Acutely Ill Patients(free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)

 

8 – Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements – BMJ Open (free)

Related Guidelines: 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free) AND Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)

 

9 – Overdiagnosis of COPD in Subjects With Unobstructed Spirometry – CHEST (link to abstract – $ for full-text)

Commentary: How Many Patients with Diagnosed COPD Truly Have It? – NEJM Journal Watch (free for a limited period)

 

10 – Association Between Soft Drink Consumption and Mortality in 10 European Countries – JAMA Internal Medicine (free for a limited period)

Commentaries: Large European Study Links Soda Consumption to Greater Risk of Mortality, Including From Parkinson – AJMC (free) AND Want to live longer? You may want to ditch these drinks – CNN (free) AND Soft drinks, including sugar-free, linked to increased risk of early death – The Guardian (free) AND Soft drinks – sugared or low-calorie – may raise the risk of early death – Reuters (free)

 


 

1 – Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice. An Official American Thoracic Society Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine (free)

Commentary: New ATS Clinical Practice Guideline: Diagnosing Fungal Infections – American Thoracic Society (free)

 

2 – Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 

3 – Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 

4 – Antithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: AFIRE Supports Rivaroxaban Monotherapy in A-fib Patients With Stable CAD – TCTMD (free) AND Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease – AFIRE – American College of Cardiology (free)

Related: Meta-Analysis of Oral Anticoagulant Monotherapy as an Antithrombotic Strategy in Patients With Stable Coronary Artery Disease and Nonvalvular Atrial Fibrillation – American Journal of Cardiology (link to abstract – $ for full-text)

 

5 – Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial – The Lancet (link to abstract – $ for full-text)

Commentary: Bypass surgery and coronary stenting yield comparable 10-year survival – European Society of Cardiology (free)

Related Meta-Analysis: Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease (link to abstract) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis (free)

 

6 – Association of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity – JAMA (free for a limited period)

Editorial: The Role of Bariatric Surgery in Managing the Macrovascular Complications of Obesity-Related Type 2 Diabetes (free for a limited period)

Commentaries: Weight-Loss Surgery Associated with 40% Reduction in Risk of Death and Heart Complications in Patients with Diabetes and Obesity, Study Shows – Cleveland Clinic (free) AND Fewer cardiovascular events seen in diabetics after weight-loss surgery – Reuters (free) AND Metabolic Surgery Improves CV Outcomes in Patients With Diabetes, Obesity – American College of Cardiology (free) AND Weight-Loss Surgery May Reduce Heart Risks in People With Type 2 Diabetes – The New York Times (10 articles per month are free)

Related Studies: Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events (link to abstract) AND Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)

 

7 – Contraceptive eligibility for women at high risk of HIV: Guidance statement – Recommendations on contraceptive methods used by women at high risk of HIV – World Health Organization (free PDF)

News Release: WHO revises recommendations on hormonal contraceptive use for women at high HIV risk (free)

Commentary: WHO: All Forms of Contraception OK for Women at High HIV Risk – MedPage Today (free registration required)

Related Randomized Trial: No Difference in HIV Incidence with Different Forms of Contraception (free study and commentaries)

 

8 – Study Finds No ‘Gay Gene,’ But Some Question Whether The Search Should Have Started At All – CommonHealth (free)

Original Study: Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior – Science (free for a limited period)

Other commentaries: No ‘gay gene’: Massive study homes in on genetic basis of human sexuality – Nature (free) AND Genetics may explain up to 25% of same-sex behavior, giant analysis reveals – Science (free) AND Search For ‘Gay Genes’ Comes Up Short In Large New Study – NPR (free) AND Many Genes Influence Same-Sex Sexuality, Not a Single ‘Gay Gene’ – The New York Times (10 articles per month are free) AND No single gene associated with being gay – BBC (free)

 

9 – A community-based comprehensive intervention to reduce cardiovascular risk in hypertension (HOPE 4): a cluster-randomised controlled trial – The Lancet (free registration required)

Commentaries: Non-physician health workers lead new approach to lowering risk of world’s number one cause of death – The Lancet (free) AND Nonphysician, Community Intervention Curbs CV Risk Factors: HOPE 4 – TCTMD (free) AND It takes a community to lower cardiovascular risk – McMaster University (free)

 

10 – World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions – The Lancet Global Health (free)

Invited Commentary: Cardiovascular disease risk prediction models: challenges and perspectives (free)

 


 

1 – 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: The Task Force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC)

News Release: Pollution and noise reduction advised in ESC guidelines on chronic coronary syndromes (free)

 

2 – 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC) (free)

 

3 – The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC): Developed in collaboration with the Association for European Paediatric and Congenital Cardiology (AEPC) (free)

 

4 – 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) (free)

 

5 – 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: The Task Force for diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD) (free)

 

6 – Maximum-fixed energy shocks for cardioverting atrial fibrillation – European Heart Journal (free)

Commentary: Comparison of High vs. Escalating Shocks – CHESS – American College of Cardiology (free)

 

7 – Complete Revascularization with Multivessel PCI for Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Complete Versus Culprit-Only Revascularization Strategies to Treat Multivessel Disease After Early PCI for STEMI – COMPLETE – American College of Cardiology (free) AND Complete revascularisation is superior to culprit-lesion only intervention – European Society of Cardiology (free)

Related Cochrane Review: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (free)

Related Meta-analysis: Complete Revascularization During Primary Percutaneous Coronary Intervention Reduces Death and Myocardial Infarction in Patients With Multivessel Disease: Meta-Analysis and Meta-Regression of Randomized Trials – JACC: Cardiovascular Interventions (free)

 

8 – Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction – DAPA-HF – American College of Cardiology (free) Dapagliflozin reduces death and hospitalisation in patients with heart failure – European Society of Cardiology (free)

 

9 – HiSTORIC Trial Supports Single-Test Rule-Out of MI Using High-Sensitivity Troponin – TCTMD (free) AND Risk-Based Thresholds for hs-Troponin I Safely Speed MI Rule-Out – MedPage Today (free registration required) AND HISTORIC: Early Rule-Out Strategy Using High-Sensitivity Cardiac Troponin I Reduced Length of Stay, Hospital Readmissions in Suspected ACS Patients – American College of Cardiology (free)

Related Studies: Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival (free study and commentaries)

 

10 – High-Sensitivity Troponin and The Application of Risk Stratification Thresholds in Patients with Suspected Acute Coronary Syndrome – Circulation (free PDF)

 


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