TOP 10 Medical News Stories

Wed May 22 – 10 Stories of The Day!

22 May, 2019 | 06:19h | UTC

 

1 – Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library (free)

Summary: Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library (free)

 

2 – Galactomannan detection in broncho‐alveolar lavage fluid for invasive aspergillosis in immunocompromised patients – Cochrane Library (free)

Summary: Measuring galactomannan in lung-washing fluid to diagnose invasive aspergillosis in patients with an impaired immune system – Cochrane Library (free)

 

3 – A Contrarian View of Digital Health – Quillette (free)

 

4 – 2019 HRS/EHRA/APHRS/LAHRS focused update to 2015 expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing – EP Europace (free)

 

5 – Update in Surveillance Recommendations in Individuals with Conventional Adenomas – Current Treatment Options in Gastroenterology (free)

 

6 – Current concepts in acute liver failure – Annals of Hepatology (free)

 

7 – What’s new in oxygen therapy? – Intensive Care Medicine (free)

Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Review: Oxygen Treatment in Intensive Care and Emergency Medicine (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)

Source: Critical Care Reviews Newsletter

 

8 – Eight things we would never do regarding end-of-life care in the ICU – Intensive Care Medicine (free)

Related: Limitation of Life-Sustaining Care in the Critically Ill: A Systematic Review of the Literature – Journal of Hospital Medicine (free PDF) AND Dying with Dignity in the Intensive Care Unit – New England Journal of Medicine (free) AND Palliative care in intensive care units: why, where, what, who, when, how – BMC Anesthesiology (free) AND Ten key points about ICU palliative care – Intensive Care Medicine (free) AND Guidelines for the withdrawal of life-sustaining measures – Intensive Care Medicine (free) AND End-of-life in the ICU: moving from ‘withdrawal of care’ to a palliative care, patient-centred approach – British Journal of Anaesthesia (free) AND New concepts in palliative care in the intensive care unit – Revista Brasileira de Terapia Intensiva (free) AND The Changing Role of Palliative Care in the ICU – Critical Care Medicine (free)

Source: Critical Care Reviews Newsletter

 

9 – Infant Deaths in Sitting Devices – Pediatrics (link to abstract – $ for full-text)

News Release: Large study sheds light infant deaths in sitting devices – American Academy of Pediatrics (free)

Commentaries: Car seat danger: Babies shouldn’t sleep in car seats when not traveling – Today (free) AND Sleep-Related Car Seat Deaths Occur Most Often Outside of Travel – NEJM Journal Watch (free)

 

10 – Trends in Suicide Among Youth Aged 10 to 19 Years in the United States, 1975 to 2016 – JAMA Network Open (free)

Commentaries: Increasing Suicide Rates in Early Adolescent Girls in the United States and the Equalization of Sex Disparity in Suicide: The Need to Investigate the Role of Social Media – JAMA Network Open (free) AND Suicide Rate For Girls Has Been Rising Faster Than For Boys, Study Finds – NPR (free) AND Suicide rates in girls are rising, study finds, especially in those age 10 to 14 – CNN (free)

 


Tue May 21 – 10 Stories of The Day!

21 May, 2019 | 06:23h | UTC

 

#ATS2019 – Highlights from the 2019 Meeting of the American Thoracic Society

 

1 – Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis – JAMA (free for a limited period)

Editorial: New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research (free for a limited period)

Commentary: Big data reveals hidden subtypes of sepsis – University of Pittsburgh (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

 

2 – Early Sedation with Dexmedetomidine in Critically Ill Patients – New England Journal of Medicine (link to abstract – $ for full-text)

Just Presented at the 2019 Meeting of the American Thoracic Society.

 

3 – Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Sedation and controlled paralysis do not improve survival of ICU patients with ARDS – University of Pittsburgh (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

 

4 – Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Treatment Changes for Mild Asthma? – NEJM Journal Watch (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

 

5 – Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Large portion of patients with mild persistent asthma and low sputum eosinophils respond equally well to inhaled corticosteroids as placebo – NIH News Releases (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

 

6 – Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Nintedanib slows lung function decline in SSc-associated interstitial lung disease – Medicine Matters (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

 

7 – Google’s AI improves accuracy of lung cancer diagnosis, study shows – STAT (free)

See also: A.I. Took a Test to Detect Lung Cancer. It Got an A. – The New York Times (10 articles per month are free)

Original Article: End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography – Nature Medicine (link to abstract – $ for full-text)

 

8 – Viewpoint: Millions Take Gabapentin for Pain. But There’s Scant Evidence It Works. – The New York Times (10 articles per month are free)

Related: Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free) AND Benefits and safety of gabapentinoids in chronic low back pain (free) AND Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs (link to abstract)

 

9 – Viewpoint: Artificial Intelligence in Health Care: Will the Value Match the Hype? – JAMA (free for a limited period)

 

10 – SCAI clinical expert consensus statement on the classification of cardiogenic shock – Catheterization Cardiovascular Interventions (free) (via @paomorejon)

Commentaries: SCAI releases multi-society endorsed consensus on the classification stages of cardiogenic shock – Society for Cardiovascular Angiography and Interventions (free) AND SCAI Clinical Expert Consensus Statement on Cardiogenic Shock – American College of Cardiology (free)

“Endorsed by the American College of Cardiology (ACC), the American Heart Association (AHA), the Society of Critical Care Medicine (SCCM), and the Society of Thoracic Surgeons (STS) in April 2019”

 


Mon May 20 – 10 Stories of The Day!

20 May, 2019 | 00:01h | UTC

 

1 – EULAR recommendations for the management of antiphospholipid syndrome in adults – Annals of Rheumatic Diseases (free)

Related: Diagnosing and treating antiphospholipid syndrome: a consensus paper – The Netherlands Journal of Medicine (free PDF) AND Guidelines on the investigation and management of antiphospholipid syndrome – British Journal of Haematology (free)

 

2 – ACSM Scientific Pronouncements: Physical Activity Guidelines for Americans – American College of Sports Medicine (free articles)

News Release: ACSM Publishes Science Behind the Updated Physical Activity Guidelines for Americans – American College of Sports Medicine (free)

Original Guideline: Physical Activity Guidelines for Americans (free resources)

 

3 – New-onset atrial fibrillation in adult critically ill patients: a scoping review – Intensive Care Medicine (free) (via @AndersPerner)

 

4 – Management of Hepatitis C in 2019 – JAMA (free for a limited period)

 

5 – Digital Medicine: A Primer on Measurement – Digital Biomarkers (free)

 

6 – Hospitals look to computers to predict patient emergencies before they happen – STAT (free)

 

7 – Optimizing cancer pain management in resource-limited settings – Supportive Care in Cancer (free)

 

8 – Evaluation of the Solitary Pulmonary Nodule – Internal Medicine Journal (free)

Related: Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017 – Radiology (free) AND Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (free) AND British Thoracic Society guidelines for the investigation and management of pulmonary nodules (free) AND Management pathways for solitary pulmonary nodules – Journal of Thoracic Disease (free)

 

9 – Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source – New England Journal of Medicine (free)

Commentary: Dabigatran After Embolic Stroke of Undetermined Source – American College of Cardiology (free)

 

10 – Association of Sugary Beverage Consumption With Mortality Risk in US Adults: A Secondary Analysis of Data From the REGARDS Study – JAMA Network Open (free)

Commentaries: Are Fruit Juices Just as Unhealthy as Sugar-Sweetened Beverages? – JAMA Network Open (free) AND Fruit juice may increase death risk as much as sugary drinks – UPI (free) AND Expert reaction to study looking at sugary drinks, fruit juice and risk of premature death in US adults – Science Media Centre (free)

Author Interview: Association of Sugary Beverage Consumption With Mortality Risk in US Adults; Trends in Suicide Among US Youth Aged 10 to 19 Years, 1975 to 2016 (free audio)

 


Fri May 17 – 10 Stories of The Day!

17 May, 2019 | 07:04h | UTC

 

1 – National, regional, and worldwide estimates of low birthweight in 2015, with trends from 2000: a systematic analysis – The Lancet Global Health (free)

Commentaries: Low birthweight: will new estimates accelerate progress? – The Lancet Global Health (free) AND AND Too many babies are born too small – World Health Organization (free) AND 1 in 7 babies worldwide born with a low birthweight – London School of Hygiene & Tropical Medicine (free) AND UNICEF-WHO Low Birthweight Estimates: Levels and trends 2000-2015 – UNICEF (free) AND Countries must up their game to reduce low birth weights, warns UN-backed report – UN News (free)

 

2 – Home-Based Cardiac Rehabilitation: A Scientific Statement From the American Association of Cardiovascular and Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology (free)

Summaries: Scientific Statement on Home-Based Cardiac Rehabilitation – American College of Cardiology (free) AND Top Things to Know:
Home-Based Cardiac Rehabilitation – American Heart Association
(free)

News Releases: New Scientific Statement Explores Home-Based Cardiac Rehab Strategy – American College of Cardiology (free) AND Home-based cardiac rehabilitation is an option to overcome barriers of traditional cardiac rehabilitation – American Heart Association (free)

Commentaries: Home-based heart rehab may help patients who can’t get to clinics – Reuters (free) AND Home-Based Cardiac Rehab a “Reasonable Option” – NEJM Journal Watch (free)

 

3 – 2019 ASCO: Low-Fat Diet May Reduce the Risk of Death From Breast Cancer in Postmenopausal Women – The ASCO Post (free)

See also: Healthy diet cuts risk of dying from breast cancer in older women – Reuters (free) AND Less fat, more fruit may cut risk of dying of breast cancer – Associated Press (free) AND Balanced, Low-Fat Diet Reduces Risk of Death From Breast Cancer in Postmenopausal Women – ASCO News Releases (free)

 

4 – Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake – Cell Metabolism (free for a limited period)

Commentaries: Controlled study links processed food to increased calorie consumption – Cell Press (free) AND NIH study finds heavily processed foods cause overeating and weight gain – NIH News Releases (free) AND Ultra-processed foods lead to higher calorie consumption and weight gain – Reuters (free) AND Expert reaction to study looking at processed food, calorie consumption and weight gain – Science Media Centre (free) AND Ultra-processed food causes weight gain – firm evidence at last – The Conversation (free)

 

5 – Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Early weight-loss surgery may improve type 2 diabetes, blood pressure outcomes – NIH/National Institute of Diabetes and Digestive and Kidney Diseases (free) AND Obesity surgery benefits may be bigger for teens than adults – Associated Press (free)

 

6 – Does Atelectasis Cause Fever After Surgery? Putting a Damper on Dogma – JAMA Surgery (free for a limited period)

 

7 – How Much Alcohol Can You Drink Safely? – The New York Times Magazine (10 articles per month are free)

Related Articles: Alcohol Use and Burden for 195 Countries and Territories (free) AND Meta-analysis: Risk Thresholds for Alcohol Consumption (free )

 

8 – Comparison of the New Oral Anticoagulants and Warfarin in Patients with Atrial Fibrillation and Valvular Heart Disease: Systematic Review and Meta-Analysis – Drugs in R&D (free)

The efficacy and safety of NOACs as thromboprophylaxis for AF and VHD are similar to those of warfarin.”

 

9 – Normal Body Temperature: A Systematic Review – Open Forum Infectious Diseases (free) (via @PaulSaxMD see Tweet)

See also: Interest “Tweetorial” about the definition of a fever (twitter thread)

 

10 – Association Between Incident Exposure to Benzodiazepines in Early Pregnancy and Risk of Spontaneous Abortion – JAMA Psychiatry (free for a limited period)

Commentaries: Benzodiazepine Use in Early Pregnancy Increases Risk of Miscarriage, Study Suggests – Psychiatry News Alert (free) AND Assess benzodiazepines’ risk-benefit before use in early pregnancy – OnMedica (free) AND Benzodiazepine Use in Early Pregnancy Linked to Spontaneous Abortion – MPR (free)

 


Thu May 16 – 10 Stories of The Day!

16 May, 2019 | 05:29h | UTC

 

1 – Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline – The BMJ (free)

Commentaries: Experts advise against hormone treatment in adults with mild thyroid problems – The BMJ (free) AND Experts: Don’t Treat Subclinical Hypothyroidism – NEJM Journal Watch (free)

Related: Meta-Analysis: Treating Subclinical Hypothyroidism is Not Associated with Quality of Life and Thyroid-Related Symptoms (link to abstract and commentaries) AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)

 

2 – Management of Infertility – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF)

 

3 – Transition Planning for the Senior Surgeon: Guidance and Recommendations From the Society of Surgical Chairs – JAMA Surgery (free for a limited period)

Invited Commentary: Planning for Retiring From Operating (free for a limited period)

Author Interview: Transition Planning for the Senior Surgeon (free audio)

 

4 – Chronic use of tramadol after acute pain episode: cohort study – The BMJ (free)

Commentaries: Risk of Prolonged Use With Tramadol vs Other Short Acting Opioids Examined – MPR (free) AND ‘There really is no safe opioid’: Study finds tramadol isn’t a less addictive painkiller – CBC (free)

 

5 – Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Familial Hypercholesterolemia Seen in 10% of Young MI Patients – TCTMD (free) AND Familial Hypercholesterolemia Among Young Adults With MI – American College of Cardiology (free)

 

6 – Otitis Externa: Investigation and Evidence-Based Treatment – Deutsches Ärzteblatt International (free)

 

7 – Bowel obstruction: a narrative review for all physicians – World Journal of Emergency Surgery (free)

 

8 – Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017 – Nature (free)

Commentaries: ‘Striking’ differences in rates of HIV/AIDS within African nations – Institute for Health Metrics and Evaluation (free) AND New HIV Map Offers Most Detailed Look Yet At The Epidemic – NPR (free)

 

9 – Association of a Beverage Tax on Sugar-Sweetened and Artificially Sweetened Beverages With Changes in Beverage Prices and Sales at Chain Retailers in a Large Urban Setting – JAMA (free for a limited period)

Editorial: Sugar-Sweetened Beverage Taxes: Emerging Evidence on a New Public Health Policy (free)

Commentaries: Soda Taxes Are a ‘No-Brainer’ for Public Health, Says the Author of a New Study on Them – TIME (free) AND Sales of Sweetened Drinks Fell 38% After Philadelphia Beverage Tax – AJMC (free)

Related: Soda Tax Linked to a 50 Percent Reduction in Sugary Drink Consumption (several policies, guidelines, studies and commentaries on the subject) AND AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free statement and commentaries)

 

10 – Prevalence of Burnout in Medical and Surgical Residents: A Meta-Analysis – International Journal of Environmental Research and Public Health (free)

The aggregate prevalence of burnout was 51.0% among residents. Subgroup analysis by specialty showed that radiology (77.16%), neurology (71.93%), and general surgery (58.39%) were the top three specialties with the highest prevalence of burnout.

 


Wed May 15 – 10 Stories of The Day!

15 May, 2019 | 07:05h | UTC

 

1 – Risk reduction of cognitive decline and dementia – World Health Organization (free PDF)

News Release: Adopting a healthy lifestyle helps reduce the risk of dementia – World Health Organization (free)

Commentaries: WHO issues first advice on dementia: exercise and don’t smoke – Reuters (free) AND Eat well, exercise more: New global guidelines to reduce risk of dementia – CNN (free) AND Expert reaction to WHO Guidelines on risk reduction of cognitive decline and dementia – Science Media Centre (free)

 

2 – The Exercise and Sports Science Australia position statement: Exercise medicine in cancer management – Journal of Science and Medicine in Sport (free)

 

3 – Association of Unrecognized Obstructive Sleep Apnea With Postoperative Cardiovascular Events – JAMA (free for a limited period)

Editorial: Unrecognized Obstructive Sleep Apnea and Postoperative Cardiovascular Complications: A Wake-up Call – JAMA (free for a limited period)

Video Summary: Association of Undiagnosed Obstructive Sleep Apnea With Postoperative Cardiovascular Complications (free)

Commentary: Sleep apnea tied to heart problems after surgery – Reuters (free)

 

4 – Same-Day vs Different-Day Elective Upper and Lower Endoscopic Procedures by Setting – JAMA Internal Medicine (free for a limited period)

Commentaries: Improving the Delivery of Common Medical Procedures to Achieve Value-Based Care – JAMA Internal Medicine (free for a limited period) AND When possible, upper and lower GI endoscopies should be done on same day – Johns Hopkins University School of Medicine (free)

 

5 – The Dangers of Ignoring the Beers Criteria—The Prescribing Cascade – JAMA Internal Medicine (free for a limited period)

Original Article: AGS 2019 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults (link to abstract – $ for full-text)

 

6 – Potentially Inappropriate Prescribing Among Older Persons: A Meta-Analysis of Observational Studies – Annals of Family Medicine (free)

News Release: Inappropriate prescribing can lead to adverse outcomes – American Academy of Family Physicians (free)

 

7 – Alex Nowbar’s journal reviews, 14 May 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

8 – The Development of Pathways in Palliative Medicine: Definition, Models, Cost and Quality Impact – Healthcare (free) (via @Abraham_RMI)

 

9 – Is incident rheumatoid arthritis interstitial lung disease associated with methotrexate treatment? Results from a multivariate analysis in the ERAS and ERAN inception cohorts – BMJ Open (free)

Commentary: Methotrexate Use Not Linked to Interstitial Lung Disease in RA – RheumNow (free)

 

10 – News Release: Whole body MRI may help to detect spread of cancers more quickly – The Lancet (free)

MRI for Lung Cancer Staging: Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed non-small-cell lung cancer: the prospective Streamline L trial – The Lancet Respiratory Medicine (free) AND Commentary: Whole-body MRI for lung cancer staging: a step in the right direction – The Lancet Respiratory Medicine (free)

MRI for Colorectal Cancer Staging: Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial – The Lancet Gastroenterology & Hepatology (free) AND Commentary: Thinking outside the box: a more efficient diagnostic approach in metastatic colorectal cancer – The Lancet Gastroenterology & Hepatology (free)

 


Tue May 14 – 10 Stories of The Day!

14 May, 2019 | 06:16h | UTC

 

1 – Significance of psychosocial factors in cardiology: update 2018 – Clinical Research in Cardiology (free)

 

2 – 2019 HRS Expert Consensus Statement on Evaluation, Risk Stratification, and Management of Arrhythmogenic Cardiomyopathy – Heart Rhythm (free PDF)

Commentary: HRS releases consensus statement on arrhythmogenic cardiomyopathy: 5 things to know – Cardiovascular Business (free)

 

3 – Obesity in the critically ill: a narrative review – Intensive Care Medicine (free)

Related Reviews: The Crashing Obese Patient – West Journal of Emergency Medicine (free) AND ARDS in Obese Patients: Specificities and Management – Critical Care (free)

Source: Critical Care Reviews Newsletter

 

4 – Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial – The Lancet (free)

Invited Commentary: Antibiotics for operative vaginal delivery: practice-changing data – The Lancet (free)

 

5 – Estimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies: A Cost-effectiveness Analysis – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Screening Options for Preventing Cervical Cancer (free for a limited period)

Author Interview: Estimated Quality of Life and Economic Outcomes Associated With Cervical Cancer Screening (free audio)

“Cytologic testing every 3 years and low-cost high-risk human papillomavirus testing every 5 years both may be considered reasonable cervical cancer screening options.”

 

6 – Spreading and scaling up innovation and improvement – The BMJ (free)

 

7 – Thyroid and Cardiovascular Disease Research Agenda for Enhancing Knowledge, Prevention, and Treatment – Circulation (free PDF) (via @paomorejon see Tweet)

Commentary: New recommendations for a thyroid and cardiovascular disease research agenda – Mary Ann Liebert, Inc (free)

 

8 – Frequency of Intracranial Hemorrhage With Low-Dose Aspirin in Individuals Without Symptomatic Cardiovascular Disease: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)

Commentaries: Low-dose aspirin linked to bleeding in the skull, new report says – CNN (free) AND Study links low-dose aspirin to bleeding inside the skull – UPI (free)

 

9 – Speaking up to prevent harm: A systematic review of the safety voice literature – Safety Science (free)

 

10 – Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank: A Population-based Prospective Cohort Study – European Urology Focus (free)

 


Mon May 13 – 10 Stories of The Day!

13 May, 2019 | 02:14h | UTC

 

1 – 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias – Heart Rhythm (free)

See also: Executive Summary (free)

 

2 – Kissing may be an important and neglected risk factor for oropharyngeal gonorrhoea: a cross-sectional study in men who have sex with men – Sexually Transmitted Infections (free)

Commentary: Deep kissing – a neglected route for throat gonorrhea – OnMedica (free) AND Deep Kissing Might Spread Oropharyngeal Gonorrhea in MSM – NEJM Journal Watch (free)

 

3 – Association of High Intakes of Vitamins B6 and B12 From Food and Supplements with Risk of Hip Fracture Among Postmenopausal Women in the Nurses’ Health Study – JAMA Network Open (free)

 

4 – “The Case of the Magician’s Sleight” – EMNerd (free)

See also: EXTEND Alteplase Shenanigans! – Emergency Medicine Literature of Note (free)

Original Study: Randomized Trial: Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke (free)

Related Cochrane Review: Thrombolysis for acute ischaemic stroke (free)

Related Opinion: Thrombolytics for stroke: The evidence – First10Em (free)

“Using statistical magic to extend the time window for IV tPA” (via @emcrit see Tweet)

 

5 – Targeting Huntingtin Expression in Patients with Huntington’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Experimental Drug For Huntington’s Disease Jams Malfunctioning Gene – NPR (free) AND Huntington drug successfully lowers levels of disease-causing protein, study shows – University of British Columbia (free)

 

6 – Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus – Nature Medicine (link to abstract – $ for full-text)

Commentaries: Viruses genetically engineered to kill bacteria rescue girl with antibiotic-resistant infection – Science (free) AND Genetically Modified Viruses Help Save A Patient With A ‘Superbug’ Infection – NPR (free) AND Genetically Tweaked Viruses Just Saved A Very Sick Teen – Wired (a few articles per month are free) AND Phage therapy’s latest makeover – Nature Biotechnology (free) AND Genetically modified virus saves teen’s life, offers hope in fight against antibiotic resistance – CNN (free) AND Scientists use engineered phages to help save teen – CIDRAP (free)

 

7 – Turkish Society of Cardiology Consensus Paper on The Rational Use of Cardiac Troponins in Daily Practice – The Anatolian Journal of Cardiology (free PDF)

 

8 – Alcohol-related harm to others in England: a cross-sectional analysis of national survey data – BMJ Open (free)

Commentaries: One in five people in England harmed by others’ drinking over past year – Blog BMJ Open (free) AND One in five people harmed by other people’s drinking – OnMedica (free) AND One in five harmed by others drinking alcohol over past year, survey finds – The Guardian (free) AND Expert reaction to study quantifying the harm of other people’s drinking – Science Media Centre (free)

 

9 – Impact of non-drug therapies on asthma control: A systematic review of the literature – European Journal of General Practice (free)

 

10 – Important food sources of fructose-containing sugars and incident gout: a systematic review and meta-analysis of prospective cohort studies – BMJ Open (free)

Commentary: Meta-analysis: high intake of sugary drinks, juice tied to gout – Univadis (free registration required)

 


Fri May 10 – 10 Stories of The Day!

10 May, 2019 | 05:12h | UTC

 

1 – Prostate cancer: diagnosis and management – National Institute for Health and Care Excellence (free)

See also: NICE Quality Standard: Prostate Cancer (free)

 

2 – Association between Apgar scores of 7 to 9 and neonatal mortality and morbidity: population based cohort study of term infants in Sweden – The BMJ (free)

Commentaries: The Apgar score and association with neonatal mortality and morbidity – The BMJ Opinion (free) AND Lower ‘normal’ Apgar scores linked to poorer outcomes – OnMedica (free)

 

3 – Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials – Intensive Care Medicine (free)

Vasopressin therapy in septic shock had no effect on 28-day mortality”

 

4 – A Deep Learning Mammography-based Model for Improved Breast Cancer Risk Prediction – Radiology (free)

Commentaries: Using AI to predict breast cancer and personalize care – MIT News (free) AND Novel artificial intelligence method predicts future risk of breast cancer – Radiological Society of North America (free)

 

5 – Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes – Diabetologia (free)

Commentary: Patients with late-onset type 1 diabetes commonly treated as having type 2 diabetes – ACP Diabetes (free)

 

6 – Management of perinatal depression with non-drug interventions – The BMJ (free)

 

7 – Rising rural body-mass index is the main driver of the global obesity epidemic in adults – Nature (free)

Commentaries: Rural Areas Drive Increases in Global Obesity – Scientific American (free) AND Obesity rising faster in rural areas than cities – Imperial College London (free)

 

8 – Global alcohol exposure between 1990 and 2017 and forecasts until 2030: a modelling study – The Lancet (link to abstract – $ for full-text)

Commentaries: Targets to reduce harmful alcohol use are likely to be missed as global alcohol intake increases – The Lancet (free) AND Increases in Drinking Worldwide (1990-2017) – Psychology Today (free) AND Alcohol use soaring worldwide: The average adult now consumes about 1.7 gallons of pure alcohol per year – USA Today (free)

Related: Alcohol Use and Burden for 195 Countries and Territories (free) AND The Global Burden of Disease Attributable to Alcohol and Drug Use (free)

 

9 – Snakebite: WHO targets 50% reduction in deaths and disabilities – World Health Organization (free)

Executive Summary: A strategy for prevention and control – World Health Organization (free PDF)

WHO Fact Sheet: Snakebite envenoming (free)

See also: New WHO Strategy Aims to Halve the Global Impact of Snakebite (report and resources) AND Study: Global Mapping of Vulnerability to Snakebite Envenoming (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ – NPR Goats and Soda (free)

 

10 – Access Barriers to Antibiotics – Center for Disease Dynamics, Economics & Policy (free PDF)

News Release: Lack of Access to Antibiotics is a Major Global Health Challenge (free PDF)

Commentary: Report highlights lack of access to antibiotics – CIDRAP (free)

 


Thu May 9 – 10 Stories of The Day!

9 May, 2019 | 08:16h | UTC

 

1 – Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: IV Thrombolysis Could Be Given Up to 9 Hours After Stroke Onset in Some – NEJM Journal Watch (free)

Related Randomized Trial: MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset (free study and commentaries)

 

2 – A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine (free)

Commentaries: Progesterone could increase births in women with early pregnancy bleeding and previous miscarriage – University of Birmingham (free) AND Progesterone Was Ineffective Against Threatened Miscarriage – NEJM Journal Watch (free) AND Vaginal Progesterone May Reduce Miscarriages in Women with Bleeding in Early Pregnancy – MedicalResearch.com (free) AND Progesterone only prevents miscarriage in women with history of pregnancy loss – Reuters (free) AND Progesterone Disappoints Again for Threatened Miscarriage – MedPage Today (free registration required)

 

3 – Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial – JAMA (free)

Editorial: Filling in the Evidence About Sunscreen (free)

Commentaries: Expert reaction to study looking at sunscreen ingredients and bloodstream concentrations – Science Media Centre (free) AND High levels of sunscreen ingredients end up in the bloodstream: study – Reuters (free) AND How Sunscreen Chemicals Can Get Into Your Blood – Forbes (free) AND  How Much of Your Sunscreen is Absorbed? – MedicalResearch.com (free)

 

4 – Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage – Cochrane Library (free)

Summary: Oxytocin to prevent excessive blood loss for women during the third stage of labour – Cochrane Library (free)

Related: WHO Guideline: Uterotonics for the Prevention of Postpartum Hemorrhage (free)

 

5 – State of the Art Review: Diagnosis and management of sensory polyneuropathy – The BMJ (free for a limited period)

 

6 – Acute Flaccid Myelitis: A Clinical Overview for 2019 – Mayo Clinic Proceedings (free)

 

7 – POEMS syndrome: clinical update – Journal of Neurology (free)

 

8 – Treatment consensus for management of polymyositis and dermatomyositis among rheumatologists, neurologists and dermatologists – The Journal of Dermatology (free)

 

9 – Azithromycin during Acute COPD Exacerbations Requiring Hospitalization (BACE): a Multicentre, Randomized, Double-blind, Placebo-controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)

Commentaries: Azithromycin appears to reduce treatment failure in severe, acute COPD exacerbations – American Thoracic Society (free) AND Azithromycin May Reduce Treatment Failure in Patients With Acute Exacerbation of COPD – AJMC (free)

 

10 – Study Puts Eggs and Dietary Cholesterol Back on the Radar – JAMA (free for a limited period)

Podcast: Study Puts Eggs and Dietary Cholesterol Back on the Radar (free audio)

Original Study: Cohort Study: Associations of Dietary Cholesterol or Egg Consumption with Incident Cardiovascular Disease and Mortality (link to abstract and commentaries)

 


Page 1 of 512345

New! Updates via WhatsApp Free Email Updates Android iOS About
Stay Updated in Your Specialty
No spam, just news
Unsubscribe with one click

 

Daily

 

Weekly or Less Often 
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •