TOP 10 Medical News Stories

 

1 – Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems – The Lancet (free articles – registration required)

Summary: EAT-Lancet Commission Brief for Everyone (free)

Commentaries: New Diet Guidelines to Benefit People and the Planet: More Greens for All, Less Meat for Some – The New York Times (10 articles per month are free) AND New ‘planetary health diet’ can save lives and the planet, major review suggests – CNN (free) AND A bit of meat, a lot of veg – the flexitarian diet to feed 10bn – BBC (free)

 

2 – Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank – The BMJ (free)

Commentaries: Haemochromatosis: disorder that causes body to absorb too much iron from food may be major cause of disease – The Conversation (free) AND Haemochromatosis is linked to more disease than previously thought – The BMJ Opinion (free) AND Health impact of genetic ‘iron-overdose disease’ may have been underestimated – NHS News (free)

 

3 – Open Access 2018: A Year of Funders and Universities Drawing Lines in the Sand – Absolutely Maybe Blog (free)

Related: Will the world embrace Plan S, the radical proposal to mandate open access to science papers? – Science (free) AND The world debates open-access mandates (free) AND China Backs Bold Plan to Tear Down Journal Paywalls (free) AND Europe’s Bold Open-Access Plan Detailed (free) Groundbreaking deal makes large number of German studies free to public – Science (free)

 

4 – Appropriateness of outpatient antibiotic prescribing among privately insured US patients: ICD-10-CM based cross sectional study – The BMJ (free)

Commentaries: Nearly a fourth of outpatient antibiotics unneeded, study finds – CIDRAP (free) AND Nearly a quarter of antibiotic prescriptions for children and adults may be unnecessary – University of Michigan (free)

 

5 – Guideline: Prepregnancy counseling – Fertility and Sterility (free)

 

6 – How to get started in quality improvement – The BMJ (free)

 

7 – Ebola Has Gotten So Bad, It’s Normal – Foreign Policy (free)

Related: WHO expert: Ebola outbreak to continue at least 6 more months – CIDRAP (free)

 

8 – Summary: Hypertriglyceridemia Management According to the 2018 AHA/ACC Guideline – American College of Cardiology (free)

 

9 – Efficacy and safety of aspirin for primary prevention of cardiovascular events: a meta-analysis and trial sequential analysis of randomized controlled trials – European Heart Journal (link to abstract – $ for full-text)

Commentary: Daily Aspirin Use May Do More Harm Than Good for Healthy People – Diagnostic and Interventional Cardiology (free)

Related Study: Aspirin Did Not Prevent Deaths or Disability in Healthy Older Adults (free study and commentaries)

 

10 – Medscape National Physician Burnout, Depression & Suicide Report 2019 (free registration required)

Commentaries: Burnout Rises Above 50% in Some Specialties, New Survey Shows – Medscape (free registration required) AND No quick fix for physician burnout, depression – Reuters (free) AND More than half of physicians are burned out or depressed – HealthExec (free)

Related Perspectives: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free) AND Panic, chronic anxiety and burnout: doctors at breaking point – The Guardian (free) AND The Burnout Crisis in American Medicine – The Atlantic (free) AND Implementing Optimal Team-Based Care to Reduce Clinician Burnout – National Academy of Medicine (free) AND Physician burnout costs up to $17B a year, task force says – HealthcareDive (free)

Related Research: Physician Burnout Can Lead to Major Medical Errors (link to abstract and commentaries) AND Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction (link to abstract and commentaries) AND Systematic Review: Prevalence of Burnout Among Physicians (link to abstract and commentaries)

 


 

1 – Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization – European Heart Journal (free)

Summary: Angina After PCI – American College of Cardiology (free)

 

2 – KSHF Guidelines for the Management of Acute Heart Failure (free articles)

Part I. Definition, Epidemiology and Diagnosis of Acute Heart Failure 

Part II. Treatment of Acute Heart Failure

Part III. Specific Management of Acute Heart Failure According to the Etiology and Co-morbidity

Related: The use of diuretics in heart failure with congestion — a position statement from the Heart Failure Association of the European Society of Cardiology – European Journal of Heart Failure (free) AND Managing the Patient with Heart Failure in the Emergency Department – European Heart Journal (free)

 

3 – ‘Ten Commandments’ for the Fourth Universal Definition of Myocardial Infarction 2018 – European Heart Journal (free)

Original Article: Fourth Universal Definition of Myocardial Infarction (free)

 

4 – Opinion: Time to abandon early detection cancer screening – European Journal of Clinical Investigation (free)

 

5 – How telehealth can get healthcare to more people – World Economic Forum (free)

 

6 – Protein mania: the rich world’s new diet obsession – The Guardian (free)

 

7 – Implementing School-Based Policies to Prevent Obesity: Cluster Randomized Trial – American Journal of Preventive Medicine (free for a limited period)

Commentaries: School nutrition policies reduce weight gain – National Institutes of Health (free) AND School-based nutritional programs reduce student obesity – Yale University (free)

 

8 – Artificial intelligence in the intensive care unit – Critical Care (free)

 

9 – First International Consensus on the diagnosis and management of fibromuscular dysplasia – Vascular Medicine (free)

Commentary: First international consensus on fibromuscular dysplasia – Sage (free)

 

10 – Society of American Gastrointestinal and Endoscopic Surgeons – Five Things Physicians and Patients Should Question – Choosing Wisely (free)

Commentary: Choosing Wisely: Don’t Use Ultrasound to Evaluate Palpable Inguinal Hernia – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


 

1 – Ten threats to global health in 2019 – World Health Organization (free)

 

2 – Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza – CHEST Guideline and Expert Panel Report (free)

See other recently published CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Clinically Diagnosing Pertussis-associated Cough in Adults and Children (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Cough Due to TB and Other Chronic Infections  (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)

 

3 – Excess Burden of Mental Illness and Hospitalization in Young-Onset Type 2 Diabetes: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Mental Illness Risk Increased in Young Onset Diabetes – MedicalResearch.com (free) AND Young-onset type 2 diabetes associated with increased risk of hospitalization frequently due to mental illness – 2 Minute Medicine (free) AND Young Onset Diabetes Linked to High Rates of Mental Illness, Hospitalization – AJMC (free)

 

4 – Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Video Summary: Can a short duration of anaerobically prepared pooled FMT induce remission in ulcerative colitis? (free)

Commentary: Poo transplant effective treatment for chronic bowel condition – University of Adelaide (free)

See also: Visual Abstract (free)

 

5 – Effect of early physician follow-up on mortality and subsequent hospital admissions after emergency care for heart failure: a retrospective cohort study – Canadian Medical Association Journal (free)

Commentaries: Heart failure patients need sooner follow-up care – Reuters (free) AND Patients with heart failure have lower risk of death if seen by physician in first 7 days after ED discharge – MedicalXpress (free)

 

6 – Zackary Berger’s weekly research reviews, 14 January 2019 – The BMJ (free)

“Zackary Berger reviews the latest research from the top medical journals”.

 

7 – Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

See also: Visual Abstract (free)

Commentaries: For some multiple sclerosis patients, knocking out the immune system might work better than drugs – Science (free) AND A remarkable new study shows stem cells can reverse MS in some patients – Vox (free) AND Expert reaction to study looking at blood stem cell transplantation as a MS treatment – Science Media Centre (free)

 

8 – Opinion: The scandal of surrogates and the missing survival data in cancer trials – BMJ EBM Spotlight (free)

Related Study: Association Between Surrogate End-points and Overall Survival in Oncology (free)

 

9 – Draft Recommendation Statement: Breast Cancer: Medication Use to Reduce Risk – U.S. Preventive Services Task Force (free)

Commentary: USPSTF Reaffirms Drugs for Women at High Risk for Breast Cancer – Medscape (free registration required)

 

10 – Cardiologist-level arrhythmia detection and classification in ambulatory electrocardiograms using a deep neural network – Nature Medicine (link to abstract – $ for full-text)

Commentaries: Using Artificial Intelligence to Catch Irregular Heartbeats – NIH Director’s Blog (free) AND Machine Matches Docs for Arrhythmia Detection – MedPage Today (free registration required)

 


 

1 – American College of Physicians Ethics Manual: Seventh Edition – Annals of Internal Medicine (free)

News Release: American College of Physicians releases new edition of Ethics Manual (free)

“Genetic testing, telemedicine, end-of-life care, and human subjects research are among issues examined in new edition of ACP Ethics Manual” (from News Release)

 

2 – β-blockers, calcium antagonists, and mortality in stable coronary artery disease: an international cohort study – European Heart Journal (free)

Commentaries: Beta-Blockers, Calcium Channel Blockers, Mortality in Stable CAD – American College of Cardiology (free) AND CLARIFY: No Survival Benefit With Beta-Blockers Beyond 1 Year Post-MI in Stable CAD – TCTMD (free)

Related Studies: Effect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction (free) AND B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction (free study and commentary)

 

3 – Podcast: #135 Perioperative Medicine: Assess & Optimize Risk – The Curbsiders Internal Medicine Podcast (free audio)

 

4 – Acute infection & myocardial infarction: How afraid should we be? – PulmCrit (free)

Related Commentary: Acute Infection and Myocardial Infarction – American College of Cardiology (free)

Original Article: Acute Infection and Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)

 

5 – Opinion: Why Big Pharma must disclose payments to patient groups – The Conversation (free)

 

6 – Unethical experiments’ painful contributions to today’s medicine – CNN (free)

 

7 – The association between adolescent well-being and digital technology use – Nature Human Behavior (link to abstract – $ for full-text)

Commentaries: Technology use explains at most 0.4 percent of adolescent wellbeing, new study finds – University of Oxford (free) AND Expert reaction to adolescent well-being and digital technology use – Science Media Centre (free) AND Screen Time May Be No Worse For Kids Than Eating Potatoes – Forbes (free)

 

8 – Association of body mass index and waist-to-hip ratio with brain structure: UK Biobank study – Neurology (link to abstract – $ for full-text)

Commentaries: Excessive body fat around the middle linked to smaller brain, study says – CNN (free) AND Excessive body fat around the middle linked to smaller brain size, study finds – American Academy of Neurology (free)

 

9 – Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of panic disorder, social anxiety disorder and generalised anxiety disorder – Australian & New Zealand Journal of Psychiatry (free)

 

10 – SEOM clinical guidelines on cardiovascular toxicity (2018) – Clinical and Translational Oncology (free)

Related Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardio-Onco-Hematology in Clinical Practice. Position Paper and Recommendations – Revista Espanola de Cardiologia (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)

 


 

1 – WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free)

Related Meta-Analysis: Drugs for Treating Severe Hypertension in Pregnancy (free study and commentary)

Related Guideline: Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)

 

2 – WHO recommendations: Induction of labour at or beyond term – World Health Organization (free)

Related Cochrane Review: Induction of Labor for Improving Birth Outcomes for Women at or Beyond Term (free article and summary)

 

3 – Carbohydrate quality and human health: a series of systematic reviews and meta-analyses – The Lancet (link to abstract – $ for full-text)

Commentaries: High intake of dietary fiber and whole grains associated with reduced risk of non-communicable diseases – ScienceDaily (free) AND High-fiber diet linked to lower risk of death and chronic diseases – CNN (free) AND Expert reaction to series of systematic reviews and meta-analyses about dietary fibre and the risk of non-communicable disease – Science Media Centre (free)

 

4 – Guidelines for the peri‐operative care of people with dementia – Anaesthesia (free)

 

5 – Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases – The BMJ (free)

Commentaries: HRT patches and gels ‘may be safer’ than tablets for older women – NHS News (free) AND HRT tablets associated with increased risk of blood clots – MedicalXpress (free) AND Expert reaction to HRT and blood clots – Science Media Centre (free)

 

6 – Thyroid hormone treatment does not help adults with mildly abnormal thyroid tests – NIHR Signal (free)

Original Study: Meta-Analysis: Treating Subclinical Hypothyroidism is Not Associated with Quality of Life and Thyroid-Related Symptoms (link to abstract and commentaries)

 

7 – Effectiveness of SIESTA on Objective and Subjective Metrics of Nighttime Hospital Sleep Disruptors – Journal of Hospital Medicine (free)

Commentary: Hospital SIESTA project reduces inpatient sleep interruptions – University of Chicago Medical Center (free)

 

8 – An Observational Study of Deep Learning and Automated Evaluation of Cervical Images for Cancer Screening – JNCI: Journal of the National Cancer Institute (free)

Commentaries: AI approach outperformed human experts in identifying cervical precancer – NIH News Releases (free) AND AI identifies precancerous cervix better than human experts, report says – UPI (free)

 

9 – Screening for cardiac contractile dysfunction using an artificial intelligence–enabled electrocardiogram – Nature Medicine (link to abstract – $ for full-text)

Commentaries: Artificial Intelligence From ECGs May ID Asymptomatic LV Dysfunction – TCTMD (free) AND Mayo Clinic research uses artificial intelligence to develop inexpensive, widely available early detector of silent heart disease (free) AND AI-based EKG processing predicts early left ventricular dysfunction – Cardiovascular Business (free)

 

10 – Clinical cases referring to diagnosis and management of patients with thoracic aortic pathologies involving the aortic arch: a companion document of the 2018 European Association for Cardio-Thoracic Surgery (EACTS) and the European Society for Vascular Surgery (ESVS) expert consensus document addressing current options and recommendations for the treatment of thoracic aortic pathologies involving the aortic arch – European Journal of Cardio-Thoracic Surgery (free)

Original Guideline: Current options and recommendations for the treatment of thoracic aortic pathologies involving the aortic arch: an expert consensus document of the European Association for Cardio-Thoracic surgery (EACTS) and the European Society for Vascular Surgery (ESVS) (free)

 


 

1 – Guidelines for Colonic Diverticular Bleeding and Colonic Diverticulitis: Japan Gastroenterological Association – Digestion (free)

Related Guidelines: American Gastroenterological Association Institute Guideline on the Management of Acute Diverticulitis – Gastroenterology (free) AND Colorectal surgeon consensus with diverticulitis clinical practice guidelines – World Journal of Gastrointestinal Surgery (free) AND WSES Guidelines for the management of acute left sided colonic diverticulitis in the emergency setting – World Journal of Emergency Surgery (free)

 

2 – British Thoracic Society Guideline for bronchiectasis in adults – Thorax (free)

 

3 – Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Fewer complications found with hybrid surgery for esophageal cancer – MedicalXpress (free) AND Should Minimally Invasive Esophagectomy Now Be Standard? – Medscape (free registration required)

 

4 – HIV Viral Load and Transmissibility of HIV Infection: Undetectable Equals Untransmittable – JAMA (free for a limited period)

Related: Negligible Risk of Transmitting HIV During Sex When Viral Load is Suppressed (free study and commentary) AND UNAIDS Explainer: UNDETECTABLE = UNTRANSMITTABLE (free report and commentaries)

 

5 – Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)

Video Summary: How Effective are Opioids for Chronic Noncancer Pain? (free)

Commentaries: Opioids unlikely to provide clinically meaningful reduction in chronic non-cancer pain – 2 Minute Medicine (free) AND Opioids offer little chronic pain benefit and wane over time, study says – CNN (free)

Related: Opioid vs Nonopioid Medications in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain (free study, guideline and commentaries)

 

6 – Effects of A Communication-And-Resolution Program on Hospitals’ Malpractice Claims And Costs – Health Affairs (link to abstract – $ for full-text)

Commentaries: Study finds hospital communication-and-resolution programs do not expand liability risk – Brigham and Women’s Hospital (free) AND Effects of a communication-and-resolution program on hospitals’ malpractice claims and costs – PSNet (free) AND It’s a win-win: Hospitals should apologize for mistakes – Stanford Law School (free)

 

7 – Update: Patient Engagement in Safety – Patient Safety Network (free)

 

8 – Catheter Ablation of Atrial Fibrillation in Patients With Heart Failure: A Meta-analysis of Randomized Controlled Trials – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Catheter ablation better than drug therapy for a-fib, heart failure – UPI (free) AND Catheter Ablation Boosts Outcomes in Patients With A-fib and Heart Failure: Meta-analysis – TCTMD (free)

 

9 – ACC/AHA/SCAI/SIR/SVM 2018 Appropriate Use Criteria for Peripheral Artery Intervention – Journal of the American College of Cardiology (free)

Commentary: New Appropriate Use Criteria for Peripheral Artery Interventions: A Multisociety Collaboration – TCTMD (free) AND 2018 Appropriate Use Criteria for Peripheral Artery Intervention – American College of Cardiology (free)

 

10 – Optimal Exercise Programs for Patients With Peripheral Artery Disease: A Scientific Statement From the American Heart Association – Circulation (free PDF)

Top Ten Things to Know: Optimal Exercise Programs for Patients With Peripheral Artery Disease (free)

Commentaries: AHA Scientific Statement: Get PAD Patients Moving to Improve Symptoms and QoL – TCTMD (free) AND Promoting Exercise Therapy in Peripheral Artery Disease: Time to Get Moving – AHA News (free)

 


 

1 – 2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections – World Journal of Emergency Surgery (free)

 

2 – Antibiotic use in patients with abdominal injuries: guideline by the Korean Society of Acute Care Surgery – Annals of Surgical Treatment and Research (free)

 

3 – Booklet: Findings from the Global Burden of Disease Study 2017 – Institute for Health Metrics and Evaluation (free)

Original Report: Global Burden of Disease Study 2017 – The Lancet (free articles)

 

4 – The best dose of aspirin for cardiovascular protection may depend on body weight – NIHR Signal (free)

Original Article: Effects of Aspirin for CV Disease Prevention According to Bodyweight and Dose (free study and commentaries)

 

5 – Effect of a Biobehavioral Environmental Approach on Disability Among Low-Income Older Adults: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentaries: Home Modifications to Reduce Disability in Older Adults With Functional Disability – JAMA Internal Medicine (free for a limited period)

 

6 – Association of Corticosteroid Treatment With Outcomes in Adult Patients With Sepsis: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Steroids Associated With Reduced Mortality in Adults with Sepsis – MedicalResearch.com (free)

Related Guideline: Corticosteroid Therapy for Sepsis – The BMJ (free)

Related Meta-Analysis: Corticosteroids in Sepsis (link to abstract) AND Corticosteroids for Patients with Septic Shock (free)

 

7 – State of The Art Review: Sepsis associated acute kidney injury – The BMJ (free)

 

8 – Perspective: Are medical editors responsible if articles they publish cause harm? – CMAJ News (free)

 

9 – Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST – Health Technology Assessment (free)

 

10 – Cardiac Troponin Elevation in Patients Without a Specific Diagnosis – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Non-ACS Troponin Elevation and Outcomes – American College of Cardiology (free) AND Don’t Dismiss High Troponin Without Classical MI – MedPage Today (free registration required) AND Cardiac troponin elevation without definitive diagnosis associated with higher mortality – 2 Minute Medicine (free)

 


 

1 – The Year in Cardiology 2018 – European Heart Journal (free articles)

– Prevention

– Acute Coronary Syndromes

– Arrhythmias and Cardiac Devices

– Valvular Heart Disease

– Aorta and Peripheral Circulation

– Imaging

Related: AHA names top heart disease and stroke research advances of 2018 – American Heart Association (free) AND 2018 Top Clinical Trials and Journal Scans – American College of Cardiology (free)

 

2 – Guideline: Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence (free)

Related Guidelines: Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians (free) AND Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement – Journal of Nephrology (free) AND Medical Management of Kidney Stones: AUA Guideline (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART II (free)

 

3 – Routine preoperative medical testing for cataract surgery – Cochrane Library (free)

Summary: Routine preoperative medical testing for cataract surgery – Cochrane Library (free)

Related Perspective: A Preoperative Medical History and Physical Should Not Be a Requirement for All Cataract Patients – Journal of General Internal Medicine (free)

Related Research: Preoperative Medical Testing in Medicare Patients Undergoing Cataract Surgery – New England Journal of Medicine (free)

This review has shown that routine preoperative testing does not increase the safety of cataract surgery.”

 

4 – Keep O2 saturations at 96% or below for hospitalized patients: expert panel – PulmCC (free)

Original Article: Oxygen therapy for acutely ill medical patients: a clinical practice guideline – The BMJ (free study and commentary)

 

5 – Point and Counterpoint: Should the Surviving Sepsis Campaign Guidelines Be Retired?

POINT: Should the Surviving Sepsis Campaign Guidelines Be Retired? Yes – Chest (free)

COUNTERPOINT: Should the Surviving Sepsis Campaign Guidelines Be Retired? No – Chest (free)

Related: The 2018 Surviving Sepsis Campaign’s Treatment Bundle: When Guidelines Outpace the Evidence Supporting Their Use (free guideline and commentaries)

 

6 – Will the world embrace Plan S, the radical proposal to mandate open access to science papers? – Science (free)

Related: The world debates open-access mandates (free) AND China Backs Bold Plan to Tear Down Journal Paywalls (free) AND Europe’s Bold Open-Access Plan Detailed (free)

 

7 – SEOM clinical guidelines to primary prevention of cancer (2018) – Clinical and Translational Oncology (free)

 

8 – Operative treatment versus nonoperative treatment of Achilles tendon ruptures: systematic review and meta-analysis – The BMJ (free)

Commentaries: Surgeons should know when not to operate – The BMJ Opinion (free) AND Surgery or Not for Achilles Rupture? Meta-Analysis Finds Mixed Bag – NEJM Journal Watch (free)

 

9 – Identifying facial phenotypes of genetic disorders using deep learning – Nature Medicine (link to abstract – $ for full-text)

Commentaries: AI face-scanning app spots signs of rare genetic disorders – Nature News (free) AND Artificial intelligence could diagnose rare disorders using just a photo of a face – Science Magazine (free)

 

10 – Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life – Cochrane Library (free)

Summary: Vitamin and mineral supplementation for preventing cognitive deterioration in cognitively healthy people in mid and late life – Cochrane Library (free)

Commentary: Preventing dementia: do vitamin and mineral supplements have a role? – Evidently Cochrane (free)

 


 

1 – Special Issue: Patient Optimization Before Surgery – Anaesthesia (free supplement)

Editorial: Patient optimisation before surgery: a clear and present challenge in peri‐operative care

– Risk prediction models for major surgery: composing a new tune

– Shared decision‐making in peri‐operative medicine: a narrative review

– Multi‐modal prehabilitation: addressing the why, when, what, how, who and where next?

– Pre‐operative nutrition and the elective surgical patient: why, how and what?

– Pre‐operative respiratory optimisation: an expert review

– Optimisation of pre‐operative anaemia in patients before elective major surgery – why, who, when and how?

– Pre‐operative optimisation of the surgical patient with diagnosed and undiagnosed diabetes: a practical review

– Pre‐operative cardiac optimisation: a directed review

– Peri‐operative optimisation of elderly and frail patients: a narrative review

– Peri‐operative care pathways: re‐engineering care to achieve the ‘triple aim’

– Pre‐optimisation of patients undergoing emergency laparotomy: a review of best practice

 

2 – Sustainability of Blood Pressure Reduction in Black Barbershops – Circulation (free)

Commentaries: One year later, barbershop intervention continues to lower blood pressure – American Heart Association (free) AND Barbershop Intervention for High BP Has Lasting Effects – TCTMD (free) AND How barbershops could help lower blood pressure – CNN (free)

Related Studies: Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops (free study and commentaries) AND Community-Based Interventions to Improve Cardiovascular Risk in High-Risk Patients (free study and commentaries)

 

3 – Association of the Hospital Readmissions Reduction Program With Mortality Among Medicare Beneficiaries Hospitalized for Heart Failure, Acute Myocardial Infarction, and Pneumonia – JAMA (link to abstract – $ for full-text)

Commentaries: Did This Health Care Policy Do Harm? – The New York Times (10 articles per month are free) AND Study Finds Implementation of the Hospital Readmissions Reduction Program Associated With Increase in Patient-Level Mortality – Beth Israel Deaconess Medical Center (free) AND Penalties For Hospital Readmissions May Boost Deaths, Study Finds – CommonHealth (free)

 

4 – How does exercise treatment compare with antihypertensive medications? A network meta-analysis of 391 randomised controlled trials assessing exercise and medication effects on systolic blood pressure – British Journal of Sports Medicine (link to abstract – $ for full-text)

Commentaries: Exercise ‘as good as medicine’ for controlling high blood pressure – NHS Choices (free) AND Exercise may be as good at lowering blood pressure as drugs – OnMedica (free)

 

5 – FDA warns about increased risk of ruptures or tears in the aorta blood vessel with fluoroquinolone antibiotics in certain patients – U.S. Food & Drug Administration (free)

Commentary: FDA: Fluoroquinolones may cause aortic rupture in some – CIDRAP (free)

Related: Meta-analysis: Fluoroquinolones and the Risk of Aortopathy (free) AND Fluoroquinolone use and risk of aortic aneurysm and dissection (free study and commentaries) AND Committee Recommends New Restrictions on the use of Fluoroquinolones (free report and commentaries) AND FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions (free report and commentaries) AND When antibiotics turn toxic (free commentary)

 

6 – Clinical Update: Perioperative Glucose Control in Patients with Diabetes Undergoing Elective Surgery – JAMA (free for a limited period)

 

7 – Ann Robinson’s research reviews, 7 January 2019 – The BMJ (free)

Ann Robinson reviews the latest research from the top medical journals.

 

8 – ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2019 Appropriate Use Criteria for Multimodality Imaging in the Assessment of Cardiac Structure and Function in Nonvalvular Heart Disease – Journal of the American College of Cardiology (free)

Commentary: New AUC: Multimodality Imaging in Assessing Cardiac Structure and Function in Structural Heart Disease – American College of Cardiology (free)

 

9 – Long-term Risk of Colorectal Cancer and Related Deaths After a Colonoscopy With Normal Findings – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: 10 years after negative colonoscopy, study shows lower risk of colorectal cancer and death – Kaiser Permanente (free) AND Study: Risk of cancer, death less likely 10 years after cancer-free colonoscopy – UPI (free) AND Negative colonoscopy: data support 10-year rescreening interval – Univadis (free registration required)

 

10 – Global, Regional, and Country-Specific Lifetime Risks of Stroke, 1990 and 2016 – New England Journal of Medicine (free)

Commentaries: New study reveals ‘startling’ risk of stroke – Institute for Health Metrics and Evaluation (free) AND 1 in 4 globally will have a stroke at age 25 or older, according to new study – CNN (free)

 


 

1 – WHO recommendations: Uterotonics for the prevention of postpartum haemorrhage – World Health Organization (free PDF)

News Release: WHO updates guidance to help healthcare workers prevent postpartum haemorrhage (free)

Related Meta-Analysis: Uterotonic agents for preventing postpartum haemorrhage: a network meta‐analysis – Cochrane Library (free) AND Summary: Which drug is best for reducing excessive blood loss after birth? (free)

 

2 – ADA 2019 Standards of Medical Care in Diabetes (free supplement)

News Release: Patient-centered Care is the Focus and Priority of the 2019 Standards of Medical Care in Diabetes, Published Today by the American Diabetes Association (free)

Summary of Revisions: Standards of Medical Care in Diabetes—2019 (free)

See also: Standards of Medical Care in Diabetes—2019 Abridged for Primary Care Providers (free PDF)

 

3 – Rapid Recommendations: Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline – The BMJ (free)

Commentary: Guidelines Recommend Dual Antiplatelet Therapy Immediately After TIA or Minor Stroke NEJM Journal Watch (free)

 

4 – Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza – Clinical Infectious Diseases (free)

News Release: Flu is Serious for Pregnant Women and Others at High Risk: Testing and Treatment are Key, Say IDSA Guidelines (free)

 

5 – Association of Long-term Exercise Training With Risk of Falls, Fractures, Hospitalizations, and Mortality in Older Adults: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Meta-analysis: long-term exercise cuts fall, injury risk in elders – Univadis (free registration required)

Related Study: Follow-up efficacy of physical exercise interventions on fall incidence and fall risk in healthy older adults: a systematic review and meta-analysis – Sports Medicine Open (free)

 

6 – Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies – The BMJ (free)

Editorial: Non-sugar sweeteners and health (free)

Commentaries: No evidence of sugar substitutes’ health benefits, finds study – The Guardian (free) AND Evidence Lacking for Benefits from Artificial Sweeteners – NEJM Journal Watch (free)

 

7 – International variation in radiation dose for computed tomography examinations: prospective cohort study – The BMJ (free)

 

8 – The use of diuretics in heart failure with congestion — a position statement from the Heart Failure Association of the European Society of Cardiology – European Journal of Heart Failure (free)

 

9 – 2018 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary – Circulation (free)

 

10 – Canadian Cardiovascular Society/Canadian Heart Rhythm Society Joint Position Statement on the Cardiovascular Screening of Competitive Athletes – Canadian Journal of Cardiology (free)

Related Review: Cardiac Screening of Young Athletes: a Practical Approach to Sudden Cardiac Death Prevention (free)

Related Position Statement: Recommendations for Participation in Competitive Sports of Athletes with Arterial Hypertension (free)

Related Research: Sudden Cardiac Arrest during Participation in Competitive Sports (link to abstract and commentaries)

 


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