Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)
Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
Abstract: Methotrexate in Patients with Hand Erosive Osteoarthritis Refractory to Usual Treatments: A Randomized, Double-blind, Placebo-controlled Trial (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
Abstract: Is There Any Role for Opioids in the Management of OA? (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
Ultrasound to Guide Treatment Strategy Not Beneficial in Early RA – American College of Rheumatology (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
Abstract: Risk of Immunotherapy Related Toxicity in Patients with Rheumatoid Arthritis (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
A systematic review of guidelines for managing rheumatoid arthritis – BMC Rheumatology (free)
Related Guidelines: Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence (free) AND 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis (free)
Related Commentary on Twitter
Hot off the press 🔥🔓🔥
Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis
👀👀👇👇https://t.co/MTLlPbew6Z pic.twitter.com/wiOK4ukyig
— Physio Meets Science (@PhysioMeScience) October 30, 2019
Related Commentary on Twitter
Our @NIHRSPCR funded research finds no diff in pain between people with a #goutflare randomised to either #naproxen or low-dose #colchicine, but #naproxen caused fewer #sideeffects, supporting its use as first-line treatment for #flares in #primarycare https://t.co/cKBDymlFjS
— Inflam Arthr Keele (@KeeleInflamArth) November 1, 2019
Related Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)
See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)
One Year in Review 2019 – Clinical and Experimental Rheumatology (free PDF articles)
– Systemic lupus erythematosus
– Pathogenesis of rheumatoid arthritis
– Novelties in the treatment of rheumatoid arthritis
Commentary: Network meta-analysis nixes bone benefit from vitamin D, calcium – Univadis (free registration required)
Related Meta-Analysis: Calcium or Vitamin D Supplementation and Fracture Incidence in Older Adults – JAMA (free study and commentaries)
Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy – Arthritis & Rheumatology (link to abstract – $ for full-text)
Commentaries: Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus – Physician’s Weekly (free) AND Monitoring blood hydroxychloroquine levels beneficial in SLE – Medwire News (free)
The Global Burden of Musculoskeletal Pain—Where to From Here? – American Journal of Public Health (free)
Related: Study: Musculoskeletal Conditions are Now the Second Global Cause of Years Lived with Disability (link to abstract and commentary)
Bisphosphonates for Postmenopausal Osteoporosis – JAMA (free for a limited period)
Related: Treatment consensus for management of polymyositis and dermatomyositis among rheumatologists, neurologists and dermatologists – The Journal of Dermatology (free) AND 2016 American College of Rheumatology (ACR) – European League Against Rheumatism (EULAR) Criteria for Minimal, Moderate and Major Clinical Response for Adult Dermatomyositis and Polymyositis (free) AND EULAR/ACR Classification Criteria for Adult and Juvenile Idiopathic Inflammatory Myopathies and their Major Subgroups (free)
Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rivaroxaban Not Noninferior to VKAs for Antiphospholipid Antibody Syndrome – NEJM Journal Watch (free) AND DOAC Disappoints in Thrombotic Autoimmune Disorder – MedPage Today (free registration required)
Use of oral bisphosphonates and risk of hospital admission with osteonecrosis of the jaw: Large prospective cohort study in UK women – Bone (link to abstract – $ for full-text)
Commentary: Bisphosphonates and the Risk of Osteonecrosis of the Jaw – RheumNow (free)
Source: Low back pain: joint guidelines from US Departments of Veterans Affairs, Defense – Univadis (free registration required)
Related: Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview – European Spine Journal (free) AND Clinical practice guidelines for the noninvasive management of low back pain: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration – European Journal of Pain (free) AND Low back pain and sciatica in over 16s: assessment and management – NICE (free) AND Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians (free) AND National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy – European Spine Journal (free)
Commentary: Rheumatoid arthritis: parenteral MTX tops pills for efficacy – Univadis (free registration required)
Effect of Corticosteroid-Sparing Treatment With Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients With Uveitis: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: Antimetabolite Therapy for Uveitis: Methotrexate or Mycophenolate? – JAMA Ophthalmology (free for a limited period) AND Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial – NIH News Releases (free)
#171 Lupus in Primary Care with Beth Jonas MD – The Curbsiders Internal Medicine Podcast (free audio and summary)
Related: 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus – Arthritis & Rheumatology (free) AND New EULAR Recommendations for the Management of Systemic Lupus Erythematosus (free guidelines) AND Systemic Lupus Erythematosus in Primary Care: An Update and Practical Messages for the General Practitioner – Frontiers in Medicine (free)
See also: Episode List
Related Guidelines: 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free) AND Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)
Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: High-Dose Vitamin D Might Reduce Bone Mineral Density – NEJM Journal Watch (free)
Related Commentary on Twitter
Vitamin D study: "Among healthy adults, supplementation with higher doses of vitamin D did not improve bone health." https://t.co/pugZ4Ilxke via @JAMA_current @SMCCanada cc @DietitiansCAN @medmyths @joansalgeblake @picardonhealth @CBCHealth pic.twitter.com/4BocJC1EeT
— Timothy Caulfield (@CaulfieldTim) August 27, 2019
News Release: Rheumatology and Spondylitis Organizations Release Updated Treatment Guideline for Axial Spondyloarthritis (free)
Related Guidelines: Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline (free) AND 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis (free) Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force – Annals of Rheumatic Diseases (free) AND 2018 APLAR axial spondyloarthritis treatment recommendations – International Journal of Rheumatic Diseases (free)
Related Commentary on Twitter
Update of the @eular_org #recommendations for #vaccination in adult patients with #autoimmune #inflammatory #rheumatic diseases just published. See the overarching priniciples at first glance attached!
FULTTEXT: https://t.co/BxNO6JfOws pic.twitter.com/m3yowT4zVm— ARD & RMD Open (@ARD_BMJ) August 16, 2019
Management of refractory lupus nephritis: challenges and solutions – Open Access Rheumatology (free)
Related Guidelines: Consensus of the Brazilian Society of Rheumatology for the diagnosis, management and treatment of lupus nephritis (free) AND 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus (free) AND 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus (free) AND Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus (free PDF)
Related Reviews: Update on Lupus Nephritis – Clinical Journal of the American Society of Nephrology (free) AND Immunosuppressive Treatment for Proliferative Lupus Nephritis – Cochrane Library (free) AND Induction and Maintenance Immunosuppression Treatment of Proliferative Lupus Nephritis: A Network Meta-analysis of Randomized Trials. – American Journal of Kidney Diseases (free)
Giant cell arteritis: An updated review of an old disease – Cleveland Clinic Journal of Medicine (free)
Related Guidelines: Swedish Society of Rheumatology 2018 guidelines for investigation, treatment, and follow-up of giant cell arteritis – Scandinavian Journal of Rheumatology (free) AND 2018 Update of the EULAR recommendations for the management of large vessel vasculitis – Annals of Rheumatic Diseases (free)
ANCA-Associated Vasculitis: Core Curriculum 2020 – American Journal of Kidney Diseases (free)
Related Guidelines: EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis – Annals of Rheumatic Diseases (free) AND BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis – Rheumatology (free) AND Comparisons of Guidelines and Recommendations on Managing Antineutrophil Cytoplasmic Antibody–Associated Vasculitis – Kidney International Reports (free)
Commentary: New Choosing Wisely List Tackles Opioid Prescribing, Lyme Testing – NEJM Journal Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
FDA Drug Safety Communication: FDA approves Boxed Warning about increased risk of blood clots and death with higher dose of arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR) – U.S. Food & Drug Administration (free)
Commentary: Boxed Warnings Added to Drug for Ulcerative Colitis, Arthritis – NEJM Journal Watch (free)
Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy: The FINCH 2 Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Filgotinib, a JAK1 Inhibitor, for Treatment-Resistant Rheumatoid Arthritis (free for a limited period)
Clinical Use of Bone Turnover Markers – JAMA (free for a limited period)
Advances in Understanding the Pathophysiology of Chronic Fatigue Syndrome – JAMA (free for a limited period)
Update on eosinophilic granulomatosis with polyangiitis – Allergology International (free)
Related Guidelines: Eosinophilic granulomatosis with polyangiitis (Churg–Strauss) (EGPA) Consensus Task Force recommendations for evaluation and management – European Journal of Internal Medicine (free) AND EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis – Annals of Rheumatic Diseases (free) AND BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis – Rheumatology (free)
Related Reviews: ANCA Glomerulonephritis and Vasculitis – Clinical Journal of the American Society of Nephrology (free) AND Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides – Frontiers in Immunology (free)
The diagnostic performance of dual energy CT for diagnosing gout: a systematic literature review and meta-analysis – Rheumatology (link to abstract – $ for full-text)
Commentary: Clinical Utility of Dual-Energy CT Scans for Diagnosing Gout – Renal & Urology News (free)
Tramadol for osteoarthritis – Cochrane Library (free)
Summary: Tramadol for osteoarthritis – Cochrane Library (free)
“tramadol alone or in combination with acetaminophen probably has no important benefit on mean pain or function in people with osteoarthritis, although slightly more people in the tramadol group report an important improvement”
Impact of the pattern of interstitial lung disease on mortality in rheumatoid arthritis: A systematic literature review and meta-analysis – Seminars in Arthritis and Rheumatism (link to abstract – $ for full-text)
Commentary: Lung Disease in RA: Which Factors are Linked With Mortality? – MedPage Today, via RheumNow (free)
Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Nintedanib slows lung function decline in SSc-associated interstitial lung disease – Medicine Matters (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
Millions Take Gabapentin for Pain. But There’s Scant Evidence It Works. – The New York Times (10 articles per month are free)
Related: Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free) AND Benefits and safety of gabapentinoids in chronic low back pain (free) AND Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs (link to abstract)
Medications associated with fracture risk in patients with rheumatoid arthritis – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary: Opioids, SSRIs and Steroids Increase Fracture Risk in RA – RheumNow (free)
The world-wide burden of musculoskeletal diseases: a systematic analysis of the World Health Organization Burden of Diseases Database – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentaries: Musculoskeletal conditions now second global cause of years lived with disability – BMJ (free) AND Musculoskeletal conditions 2nd global cause of years with disability – OnMedica (free)
Related Commentary on Twitter
#Musculoskeletal diseases are the second leading cause of years lived with #disability worldwide report @Lupusreference and colleagues in @ARD_BMJ https://t.co/DVdFVJsSyg #MSK pic.twitter.com/yvrQ3dvsTX
— The Lancet Rheumatology (@TheLancetRheum) May 2, 2019
Medication to reduce stomach acid may increase risk of hip fractures – NIHR Signal (free)
Original Article: Proton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies – Osteoporosis International (link to abstract – $ for full-text)
See also: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review – Agency for Healthcare Research and Quality (free) AND Full Report (free PDF) AND Evidence Summary (free PDF)
Gradual tapering TNF inhibitors versus conventional synthetic DMARDs after achieving controlled disease in patients with rheumatoid arthritis: first-year results of the randomised controlled TARA study – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary: RA flare rates unaffected by tapering strategy – Medwire News (free)
Source: EvidenceAlerts
Exercise as a Prescription for Patients with Various Diseases – Journal of Sport and Health Science (free)
This review summarizes the latest exercise prescription treatments for 26 different diseases.
#147 Rheumatoid Arthritis for the Internist – The Curbsiders Internal Medicine Podcast (free audio and summary)
“Vitamin D toxicity is rare, but clinicians must be aware of the risks of vitamin D use to limit complications related to hypercalcemia”.
Related Guidelines: Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology – Reumatología Clinica (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus – The Journal of Rheumatology (free PDF)
News Release: Many postmenopausal women do not receive treatment for osteoporosis (free)
Commentary: Managing Osteoporosis in Postmenopausal Women: An Endocrine Society Guideline – Endocrinology Advisor (free)
See also: Point of Care Algorithm (free)
Evaluating the Erythrocyte Sedimentation Rate – JAMA (free for a limited period)
Neurological Disease in Lupus: Toward a Personalized Medicine Approach – Frontiers in Immunology (free)
Related Reviews: Clinical Features of Neuropsychiatric Syndromes in Systemic Lupus Erythematosus and Other Connective Tissue Diseases (free) AND Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives (free) AND Laboratory and Neuroimaging Biomarkers in Neuropsychiatric Systemic Lupus Erythematosus: Where Do We Stand, Where To Go? (free)
Related Guidelines: Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline (free) AND 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis (free) Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force – Annals of Rheumatic Diseases (free)
Paracetamol versus placebo for knee and hip osteoarthritis – Cochrane Library (free)
Summary: Paracetamol for treating people with hip or knee osteoarthritis – Cochrane Library (free)
Related: Paracetamol: widely used and largely ineffective (free)
Related Commentary on Twitter
New Cochrane Review – 'Paracetamol (acetaminophen) versus placebo for knee and hip osteoarthritis' https://t.co/gGQs23456x @CochraneMSK High‐quality evidence indicated that paracetamol provided only minimal improvements in pain and function for people with hip/knee osteoarthritis
— The Cochrane Library (@CochraneLibrary) February 25, 2019
Commentary: New psoriasis guidelines emphasize management of comorbidities, use of biologics – ACP Internist (free)
Related Guidelines: Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics – Journal of the American Academy of Dermatology (free) AND French guidelines on the use of systemic treatments for moderate‐to‐severe psoriasis in adults – Journal of the European Academy of Dermatology and Venereology (free)
Commentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)
Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)
Effect of Magnetic Resonance Imaging vs Conventional Treat-to-Target Strategies on Disease Activity Remission and Radiographic Progression in Rheumatoid Arthritis: The IMAGINE-RA Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Rheumatoid Arthritis: Study Finds No Benefit to MRI-Guided Treatment – MedicalResearch.com (free) AND MRI-guided treatment strategy unnecessary for RA in clinical remission – Medwire News (free)
Mycophenolate mofetil versus cyclophosphamide for remission induction in ANCA-associated vasculitis: a randomised, non-inferiority trial – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary: Randomized data back EULAR guidelines for mycophenolate mofetil use in AAV – Medwire News (free)
Commentaries: Expert panel strongly recommends against surgery for the most common shoulder pain – MedicalXpress (free) AND Guidelines Recommend Against Surgery for Subacromial Pain Syndrome – NEJM Journal Watch (free)
Related Systematic Reviews: Subacromial decompression surgery for adults with shoulder pain: a systematic review with meta-analysis – British Journal of Sports Medicine (free) AND Subacromial Decompression Surgery for Rotator Cuff Disease – Cochrane Library (link to study and randomized trials on the subject)
Part 2: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)
Related: See All KDIGO Guidelines (all free)
Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology – Reumatología Clinica (free for a limited period)
Related Guidelines: The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus (free)
Related Reviews: Systemic Lupus Erythematosus in Primary Care: An Update and Practical Messages for the General Practitioner (free) AND Infection in systemic lupus erythematosus, similarities, and differences with lupus flare (free)
Subacromial decompression surgery for rotator cuff disease – Cochrane Library (free)
Summary: Surgery for rotator cuff disease (free)
Related Studies: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement (free study and commentaries) AND Arthroscopic subacromial decompression for subacromial shoulder pain (free study and commentaries)
“The data in this review do not support the use of subacromial decompression in the treatment of rotator cuff disease manifest as painful shoulder impingement.”
Proton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies – Osteoporosis International (link to abstract – $ for full-text)
Commentary: PPIs up risk for hip fracture in large meta-analysis – Univadis (free registration required)
Related Commentary on Twitter
Metanalysis of 24 PPI studies, 319,568 hip fracture pts, suggests PPIs associated with a greater risk of hip fracture (RR 1.20, 95% CI 1.14–1.28, p < 0.0001) and may be greater with higher dose (RR 1.30, 95% CI 1.20–1.40, p < 0.0001). https://t.co/nbiEIPRaXg
— Dr. John Cush (@RheumNow) December 17, 2018
Invited Commentary: Steroid injection or wrist splint for first-time carpal tunnel syndrome? (free)
“A single corticosteroid injection shows superior clinical effectiveness at 6 weeks compared with night-resting splints, making it the treatment of choice for rapid symptom response in mild or moderate carpal tunnel syndrome presenting in primary care.”
Association of Depression With Risk of Incident Systemic Lupus Erythematosus in Women Assessed Across 2 Decades – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Depression May Increase Risk of Developing an Autoimmune Disease – MedicalResearch.com (free) AND Depression Tied to Double the Risk for Lupus in Women – Medscape (free registration required)
Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: The Lancet Diabetes & Endocrinology: Vitamin D supplementation in adults does not prevent fractures, falls or improve bone mineral density – The Lancet (free) AND Vitamin D supplements don’t help bone health, major study concludes – The Guardian (free) AND Millions of Americans take vitamin D. Most should just stop – VOX (free)
Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline) AND Vitamin D Not Linked to Fracture Risk (free study and commentaries)
Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears: The ESCAPE Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: PT an Alternative to Surgery for Some Meniscal Tears – Physician’s First Watch (free)
Related: Adverse Outcomes After Arthroscopic Partial Meniscectomy (free study, commentary and guideline on the subject)
“Our Dutch multi center RCT demonstrates noninferiority of physical therapy compared with early surgery with arthroscopic partial meniscectomy for improving self-reported knee function in patients with nonobstructive meniscal tears.” (via @RudolfPoolman see Tweet)
Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Low-dose antidepressants ease back pain – Australian Hospital + Healthcare Bulletin (free) AND Antidepressant Amitriptyline Might Help Ease Low Back Pain – Physician’s First Watch (free)
Diclofenac use and cardiovascular risks: series of nationwide cohort studies – The BMJ (free)
Commentary: Diclofenac Again Tied to Major Cardiovascular Events – NEJM Physician’s First Watch (free) AND ‘A major safety concern’: World’s most common NSAID doubles CVD risk – Cardiovascular Business (free)
Related Guidelines: The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)–Pan-American League of Associations of Rheumatology (PANLAR) – Annals of Rheumatic Diseases (free)
Commentaries: Vitamin D: a pseudo-vitamin for a pseudo-disease – The Conversation (free) AND Fracture risk not linked to low vitamin D or calcium levels – OnMedica (free)
Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline)
News Release: Updated osteoarthritis guideline designed to reduce unnecessary imaging and surgery (free)
Commentary: Australia hopes to reduce unnecessary imaging, surgery with updated osteoarthritis guidelines – Health Imaging (free)
““The Guideline for the management of knee and hip osteoarthritis,” offer up exercise and weight loss as a first line defense, and warn against costly treatments using glucosamine, opioids and arthroscopic surgery, said David Hunter, co-chair of the RACGP group responsible for the update.” (from Health Imaging)
Association of Statin Exposure With Histologically Confirmed Idiopathic Inflammatory Myositis in an Australian Population – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rare Inflammatory Muscle Inflammation Increased With Statin Exposure – MedicalResearch.com (free) AND Statin Associated with an Increase in Inflammatory Myopathy – RheumNow (free) AND Statin use may increase risk for idiopathic inflammatory myositis – Healio (free registration required)
Commentary: Latin American Clinical Practice Guidelines for Lupus – RheumNow (free)
Related Guideline: The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND Executive Summary (free)
Commentaries: Osteoporosis Treatment After Hip Fracture: Bad News and Getting Worse – JAMA Network Open (free) AND Rate of Osteoporosis Drug Treatment to Prevent Recurrent Fractures Dropping – AJMC (free) AND Osteoporosis treatment often not started after hip fracture in elderly patients, study finds – ACP Internist (free)