Trial of Anifrolumab in Active Systemic Lupus Erythematosus – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: TULIP2 – Anifrolumab Succeeds in Lupus – RheumNow (free)

Periodic fever syndromes and the autoinflammatory diseases (AIDs) – Journal of Translational Autoimmunity (free)

Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: #VisualAbstract: Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X) – 2 Minute Medicine (free)

In this week's issue—Ixekizumab was superior to placebo for improving signs and symptoms in patients with non-radiographic axial spondyloarthritis at weeks 16 and 52: COAST-X, a randomised, placebo-controlled trial https://t.co/XuKDKGJns0 pic.twitter.com/bbuOReLCu2

— The Lancet (@TheLancet) January 8, 2020

Surgery for rotator cuff tears – Cochrane Library (free)

Summary: Does repair of torn rotator cuff tendons work? – Cochrane Library (free)

Related: BMJ Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain Does Not Improve Outcomes (free guideline and other resources)

Related Commentary on Twitter

Compared with non-surgical treatment, rotator cuff repair surgery may provide little or no clinically important benefits for patients in relation to important outcomes like pain, function, & overall quality of life: https://t.co/l0fuGRXNCk The latest evidence from @CochraneMSK pic.twitter.com/UXx2ij2rwf

— The Cochrane Library (@CochraneLibrary) December 18, 2019

Opioids for chronic osteoarthritis pain. An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least four weeks double‐blind duration – European Journal of Pain (link to abstract – $ for full-text)

Related Systematic Review: Oral or transdermal opioids for osteoarthritis of the knee or hip – Cochrane Library (free)

A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial – Annals of Rheumatic Diseases (free)

Commentary: We Have a Winner: Head-to-Head Study Compares Biologics for PsA – MedPage Today (free registration required)

An overview of autoantibodies in rheumatoid arthritis – Journal of Autoimmunity (free)

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee – Arthritis & Rheumatology (free)

News Release: ACR and Arthritis foundation release updated treatment guideline for OA – American College of Rheumatology (free)

Withdrawal of low-dose prednisone in SLE patients with a clinically quiescent disease for more than 1 year: a randomised clinical trial – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentary: Fewer Lupus Flares on Low Dose Steroids – RheumNow (free)

The 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4‐Related Disease – Arthritis & Rheumatology (free)

Commentary: ACR and EULAR release new classification criteria for IgG4-related disease – American College of Rheumatology (free)

Smoking cessation is associated with lower disease activity and predicts cardiovascular risk reduction in rheumatoid arthritis patients – Rheumatology (free)

Commentary: Smoking Cessation Lowers RA Disease Activity and CV Risks – RheumNow (free)

Exercise treatment effect modifiers in persistent low back pain: an individual participant data meta-analysis of 3514 participants from 27 randomised controlled trials – British Journal of Sports Medicine (free)

Clinical risk factors for Achilles tendinopathy: a systematic review – British Journal of Sports Medicine (free)

Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease: Current Concepts for the Diagnosis and Treatment – Frontiers in Medicine (free)

Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)

Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

Methotrexate Significantly Reduces Joint Damage Progression Over Placebo in Erosive Hand OA, and May Facilitate Bone Remodeling – American College of Rheumatology (free)

Abstract: Methotrexate in Patients with Hand Erosive Osteoarthritis Refractory to Usual Treatments: A Randomized, Double-blind, Placebo-controlled Trial (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

Physicians Should Consider Hydroxychloroquine to Reduce the Risk of Recurrent Congenital Heart Block in Subsequent Pregnancies of Women with Anti-SSA/Ro Antibodies – American College of Rheumatology (free)

Abstract: The Prospective Open Label Preventive Approach to Congenital Heart Block with Hydroxychloroquine (PATCH) Study Demonstrates a Reduction in the Recurrence Rate of Advanced Block (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

For People with OA, Opioids Offer Minor Pain Relief and Function Benefits, but No Quality of Life Benefit – American College of Rheumatology (free)

Abstract: Is There Any Role for Opioids in the Management of OA? (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

Ultrasound to Guide Treatment Strategy Not Beneficial in Early RA – American College of Rheumatology (free)

Abstract: Ultrasound versus Conventional Treat-To-Target Strategies in Early Rheumatoid Arthritis: Magnetic Resonance Imaging Outcome Data from a 2-year Randomized Controlled Strategy Trial (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

Half of People with RA Treated with Immune Checkpoint Inhibitors for Cancer Experience Flare, but Most Able to Continue Treatment – American College of Rheumatology (free)

Abstract: Risk of Immunotherapy Related Toxicity in Patients with Rheumatoid Arthritis (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

Gadolinium-Enhanced MRI of Shoulders Improves Diagnostic Accuracy and Helps Predict Polymyalgia Rheumatica Recurrence – American College of Rheumatology (free)

Abstract: Gadolinium-Enhanced Magnetic Resonance Imaging in Shoulders Contributes Accurate Diagnosis and Predicting Recurrence to Patients with Polymyalgia Rheumatica (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

A systematic review of guidelines for managing rheumatoid arthritis – BMC Rheumatology (free)

Related Guidelines: Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence (free) AND 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis (free)

EULAR recommendations for the management of Sjögren’s syndrome with topical and systemic therapies – Annals of Rheumatic Disease (free)

Related Guideline: The British Society for Rheumatology guideline for the management of adults with primary Sjögren’s Syndrome – Rheumatology (free)

Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis – British Journal of Sports Medicine (free)

Related Commentary on Twitter

Hot off the press 🔥🔓🔥

Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis

👀👀👇👇https://t.co/MTLlPbew6Z pic.twitter.com/wiOK4ukyig

— Physio Meets Science (@PhysioMeScience) October 30, 2019

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care – Annals of Rheumatic Diseases (free)

Related Commentary on Twitter

Our @NIHRSPCR funded research finds no diff in pain between people with a #goutflare randomised to either #naproxen or low-dose #colchicine, but #naproxen caused fewer #sideeffects, supporting its use as first-line treatment for #flares in #primarycare https://t.co/cKBDymlFjS

— Inflam Arthr Keele (@KeeleInflamArth) November 1, 2019

Effect of Weight Loss via Severe vs Moderate Energy Restriction on Lean Mass and Body Composition Among Postmenopausal Women With Obesity: The TEMPO Diet Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Total Meal Replacement Diets Effective for Weight Loss, But Can Lead To Bone Loss – MedicalResearch.com (free)

The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials – Journal of the American College of Nutrition (free)

Related Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)

See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)

One Year in Review 2019 – Clinical and Experimental Rheumatology (free PDF articles)

– Systemic sclerosis

– Sjögren’s syndrome

– Systemic lupus erythematosus

– Pathogenesis of rheumatoid arthritis

– Vasculitis

– Novelties in the treatment of rheumatoid arthritis

– Fibromyalgia

Association of Physical Activity and Fracture Risk Among Postmenopausal Women – JAMA Network Open (free)

Invited Commentary: Analyses of Physical Activity and Health—Are Our Methods Too Sedentary? – JAMA Network Open (free)

Ocular manifestations of rheumatic diseases – International Ophthalmology (free)

Comparison of fracture risk using different supplemental doses of vitamin D, calcium or their combination: a network meta-analysis of randomised controlled trials – BMJ Open (free)

Commentary: Network meta-analysis nixes bone benefit from vitamin D, calcium – Univadis (free registration required)

Related Meta-Analysis: Calcium or Vitamin D Supplementation and Fracture Incidence in Older Adults – JAMA (free study and commentaries)

Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy – Arthritis & Rheumatology (link to abstract – $ for full-text)

Commentaries: Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus – Physician’s Weekly (free) AND Monitoring blood hydroxychloroquine levels beneficial in SLE – Medwire News (free)

Risk of Infections and Cancer in Patients with Rheumatologic Diseases Receiving Interleukin Inhibitors: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentary: Interleukin Targeted Biologics Increase Risks of Infection – RheumNow (free)

The Brazilian Society of Rheumatology recommendations on investigation and diagnosis of systemic autoimmune myopathies – Advances in Rheumatology (free)

Related: Polymyositis and Dermatomyositis – Challenges in Diagnosis and Management (free reviews and guidelines)

The Global Burden of Musculoskeletal Pain—Where to From Here? – American Journal of Public Health (free)

Related: Study: Musculoskeletal Conditions are Now the Second Global Cause of Years Lived with Disability (link to abstract and commentary)

Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial – The BMJ (free)

Commentary: Amoxicillin for Chronic Low Back Pain? Are You Kidding Me? In Defense of a Controversial Clinical Trial – HIV and ID Observations (free)

Bisphosphonates for Postmenopausal Osteoporosis – JAMA (free for a limited period)

Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought? – Radiology (free)

Commentary: New evidence that hip and knee steroid injections more dangerous than thought – Boston University School of Medicine (free)

Polymyositis and dermatomyositis – challenges in diagnosis and management – Journal of Translational Autoimmunity (free)

Related: Treatment consensus for management of polymyositis and dermatomyositis among rheumatologists, neurologists and dermatologists – The Journal of Dermatology (free) AND 2016 American College of Rheumatology (ACR) – European League Against Rheumatism (EULAR) Criteria for Minimal, Moderate and Major Clinical Response for Adult Dermatomyositis and Polymyositis (free) AND EULAR/ACR Classification Criteria for Adult and Juvenile Idiopathic Inflammatory Myopathies and their Major Subgroups (free)

Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Rivaroxaban Not Noninferior to VKAs for Antiphospholipid Antibody Syndrome – NEJM Journal Watch (free) AND DOAC Disappoints in Thrombotic Autoimmune Disorder – MedPage Today (free registration required)

#177 Osteoarthritis Master Class with Tuhina Neogi MD, PhD – The Curbsiders Internal Medicine Podcast (free)

See also: Episodes List

Non-pharmacological interventions for osteoporosis treatment: Systematic review of clinical practice guidelines – Osteoporosis and Sarcopenia (free)

Exercise programmes for ankylosing spondylitis – Cochrane Library (free)

Summary: Benefits and harms of exercise programmes for people with ankylosing spondylitis – Cochrane Library (free)

Use of oral bisphosphonates and risk of hospital admission with osteonecrosis of the jaw: Large prospective cohort study in UK women – Bone (link to abstract – $ for full-text)

Commentary: Bisphosphonates and the Risk of Osteonecrosis of the Jaw – RheumNow (free)

Diagnosis of osteoporosis in statin-treated patients is dose-dependent – Annals of Rheumatic Diseases (free)

Commentary: Statins could increase or decrease osteoporosis risk — the dosage makes the difference – Complexity Science Hub Vienna (free)

Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia – Arthritis & Rheumatology (free)

Commentaries: Obesity, drinking and unhealthy diet add to gout risk – Reuters (free) AND Four Modifiable Risk Factors Tied to Hyperuricemia – HealthDay News (free)

Management of Osteoporosis in Survivors of Adult Cancers With Nonmetastatic Disease: ASCO Clinical Practice Guideline – Journal of Clinical Oncology (free)

VA/DoD Clinical Practice Guideline: Diagnosis and Treatment of Low Back Pain – Journal of General Internal Medicine (free)

Source: Low back pain: joint guidelines from US Departments of Veterans Affairs, Defense – Univadis (free registration required)

Related: Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview – European Spine Journal (free) AND Clinical practice guidelines for the noninvasive management of low back pain: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration – European Journal of Pain (free) AND Low back pain and sciatica in over 16s: assessment and management – NICE (free) AND Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians (free) AND National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy – European Spine Journal (free)

Nutrition Interventions in Rheumatoid Arthritis: The Potential Use of Plant-Based Diets. A Review – Frontiers in Nutrition (free)

Commentaries: Plant-based diet could heal your rheumatoid arthritis – News Medical (free) AND Plant-based diets may relieve rheumatoid arthritis symptoms – UPI (free)

Comparison of oral versus parenteral methotrexate in the treatment of rheumatoid arthritis: A meta-analysis – PLOS One (free)

Commentary: Rheumatoid arthritis: parenteral MTX tops pills for efficacy – Univadis (free registration required)

Effect of Corticosteroid-Sparing Treatment With Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients With Uveitis: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: Antimetabolite Therapy for Uveitis: Methotrexate or Mycophenolate? – JAMA Ophthalmology (free for a limited period) AND Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial – NIH News Releases (free)

#171 Lupus in Primary Care with Beth Jonas MD – The Curbsiders Internal Medicine Podcast (free audio and summary)

Related: 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus – Arthritis & Rheumatology (free) AND New EULAR Recommendations for the Management of Systemic Lupus Erythematosus (free guidelines) AND Systemic Lupus Erythematosus in Primary Care: An Update and Practical Messages for the General Practitioner – Frontiers in Medicine (free)

See also: Episode List

Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements – BMJ Open (free)

Related Guidelines: 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free) AND Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)

Gout and the risk of advanced chronic kidney disease in the UK health system: a national cohort study – BMJ Open (free)

Commentaries: Gout ‘more than doubles’ risk of kidney failure – University of Limerick (free) AND Gout pushes up kidney disease risks, study says – UPI (free)

Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: High-Dose Vitamin D Might Reduce Bone Mineral Density – NEJM Journal Watch (free)

Related Commentary on Twitter

Vitamin D study: "Among healthy adults, supplementation with higher doses of vitamin D did not improve bone health." https://t.co/pugZ4Ilxke via @JAMA_current @SMCCanada cc @DietitiansCAN @medmyths @joansalgeblake @picardonhealth @CBCHealth pic.twitter.com/4BocJC1EeT

— Timothy Caulfield (@CaulfieldTim) August 27, 2019

Cardiovascular Manifestations of Systemic Sclerosis: A Danish Nationwide Cohort Study – Journal of the American Heart Association (free)

Related Guideline: Consensus best practice pathway of the UK Systemic Sclerosis Study group: management of cardiac disease in systemic sclerosis – Rheumatology (free)

2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis – Arthritis Care & Research (free)

News Release: Rheumatology and Spondylitis Organizations Release Updated Treatment Guideline for Axial Spondyloarthritis (free)

Related Guidelines: Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline (free) AND 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis (free) Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force – Annals of Rheumatic Diseases (free) AND 2018 APLAR axial spondyloarthritis treatment recommendations – International Journal of Rheumatic Diseases (free)

2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases – Annals of Rheumatic Diseases (free)

Related Commentary on Twitter

Update of the @eular_org #recommendations for #vaccination in adult patients with #autoimmune #inflammatory #rheumatic diseases just published. See the overarching priniciples at first glance attached!
FULTTEXT: https://t.co/BxNO6JfOws pic.twitter.com/m3yowT4zVm

— ARD & RMD Open (@ARD_BMJ) August 16, 2019

Management of refractory lupus nephritis: challenges and solutions – Open Access Rheumatology (free)

Related Guidelines: Consensus of the Brazilian Society of Rheumatology for the diagnosis, management and treatment of lupus nephritis (free) AND 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus (free) AND 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus (free) AND Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus (free PDF)

Related Reviews: Update on Lupus Nephritis – Clinical Journal of the American Society of Nephrology (free) AND Immunosuppressive Treatment for Proliferative Lupus Nephritis – Cochrane Library (free) AND Induction and Maintenance Immunosuppression Treatment of Proliferative Lupus Nephritis: A Network Meta-analysis of Randomized Trials. – American Journal of Kidney Diseases (free)

Giant cell arteritis: An updated review of an old disease – Cleveland Clinic Journal of Medicine (free)

Related Guidelines: Swedish Society of Rheumatology 2018 guidelines for investigation, treatment, and follow-up of giant cell arteritis – Scandinavian Journal of Rheumatology (free) AND 2018 Update of the EULAR recommendations for the management of large vessel vasculitis – Annals of Rheumatic Diseases (free)

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus – Arthritis & Rheumatology (free)

See also: Video Abstract (free)

ANCA-Associated Vasculitis: Core Curriculum 2020 – American Journal of Kidney Diseases (free)

Related Guidelines: EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis – Annals of Rheumatic Diseases (free) AND BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis – Rheumatology (free) AND Comparisons of Guidelines and Recommendations on Managing Antineutrophil Cytoplasmic Antibody–Associated Vasculitis – Kidney International Reports (free)

American Academy of Pediatrics – Section on Rheumatology: Five Things Physicians and Patients Should Question – Choosing Wisely (free)

Commentary: New Choosing Wisely List Tackles Opioid Prescribing, Lyme Testing – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

FDA Drug Safety Communication: FDA approves Boxed Warning about increased risk of blood clots and death with higher dose of arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR) – U.S. Food & Drug Administration (free)

Commentary: Boxed Warnings Added to Drug for Ulcerative Colitis, Arthritis – NEJM Journal Watch (free)

V Brazilian consensus guidelines for detection of anti-cell autoantibodies on hep-2 cells – Advances in Rheumatology (free)

Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy: The FINCH 2 Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Filgotinib, a JAK1 Inhibitor, for Treatment-Resistant Rheumatoid Arthritis (free for a limited period)

Clinical Use of Bone Turnover Markers – JAMA (free for a limited period)

2018 Update of the EULAR recommendations for the management of large vessel vasculitis – Annals of Rheumatic Diseases (free)

Related Guideline: EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice – Annals of Rheumatic Diseases (free)

Advances in Understanding the Pathophysiology of Chronic Fatigue Syndrome – JAMA (free for a limited period)

EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice summary – La radiologia medica (free)

Original Guideline: EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice – Annals of Rheumatic Diseases (free)

Update on eosinophilic granulomatosis with polyangiitis – Allergology International (free)

Related Guidelines: Eosinophilic granulomatosis with polyangiitis (Churg–Strauss) (EGPA) Consensus Task Force recommendations for evaluation and management – European Journal of Internal Medicine (free) AND EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis – Annals of Rheumatic Diseases (free) AND BSR and BHPR guideline for the management of adults with ANCA-associated vasculitis – Rheumatology (free)

Related Reviews: ANCA Glomerulonephritis and Vasculitis – Clinical Journal of the American Society of Nephrology (free) AND Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides – Frontiers in Immunology (free)

The diagnostic performance of dual energy CT for diagnosing gout: a systematic literature review and meta-analysis – Rheumatology (link to abstract – $ for full-text)

Commentary: Clinical Utility of Dual-Energy CT Scans for Diagnosing Gout – Renal & Urology News (free)

2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free)

Safety of Opioids in Osteoarthritis: Outcomes of a Systematic Review and Meta-Analysis – Drugs & Aging (free)

Tramadol for osteoarthritis – Cochrane Library (free)

Summary: Tramadol for osteoarthritis – Cochrane Library (free)

“tramadol alone or in combination with acetaminophen probably has no important benefit on mean pain or function in people with osteoarthritis, although slightly more people in the tramadol group report an important improvement”

Dactylitis: A hallmark of psoriatic arthritis – Seminars in Arthritis and Rheumatism (free)

Exercise for ankylosing spondylitis: An evidence-based consensus statement – Seminars in Arthritis and Rheumatism (free)

Mixed exercise training for adults with fibromyalgia – Cochrane Library (free)

Summary: Mixed exercise programmes for adults with fibromyalgia – Cochrane Library (free)

Impact of the pattern of interstitial lung disease on mortality in rheumatoid arthritis: A systematic literature review and meta-analysis – Seminars in Arthritis and Rheumatism (link to abstract – $ for full-text)

Commentary: Lung Disease in RA: Which Factors are Linked With Mortality? – MedPage Today, via RheumNow (free)

NCCN Clinical Practice Guidelines in Oncology: 2019 Updates – The ASCO Post (free)

Ocular Manifestations of Granulomatosis with Polyangiitis: A Review of the Literature – Ophthalmology and Therapy (free)

Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Nintedanib slows lung function decline in SSc-associated interstitial lung disease – Medicine Matters (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

Millions Take Gabapentin for Pain. But There’s Scant Evidence It Works. – The New York Times (10 articles per month are free)

Related: Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free) AND Benefits and safety of gabapentinoids in chronic low back pain (free) AND Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs (link to abstract)

Medications associated with fracture risk in patients with rheumatoid arthritis – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentary: Opioids, SSRIs and Steroids Increase Fracture Risk in RA – RheumNow (free)

EULAR recommendations for the management of antiphospholipid syndrome in adults – Annals of Rheumatic Diseases (free)

Related: Diagnosing and treating antiphospholipid syndrome: a consensus paper – The Netherlands Journal of Medicine (free PDF) AND Guidelines on the investigation and management of antiphospholipid syndrome – British Journal of Haematology (free)

New concepts of pain – Best Practice & Research Clinical Rheumatology (free)

Is insulin resistance the cause of fibromyalgia? A preliminary report – PLOS One (free)

Commentary: Fibromyalgia: Is insulin resistance ‘the missing link?’ – Medical News Today (free)

Is incident rheumatoid arthritis interstitial lung disease associated with methotrexate treatment? Results from a multivariate analysis in the ERAS and ERAN inception cohorts – BMJ Open (free)

Commentary: Methotrexate Use Not Linked to Interstitial Lung Disease in RA – RheumNow (free)

Association of High Intakes of Vitamins B₆ and B₁₂ From Food and Supplements with Risk of Hip Fracture Among Postmenopausal Women in the Nurses’ Health Study – JAMA Network Open (free)

Treatment consensus for management of polymyositis and dermatomyositis among rheumatologists, neurologists and dermatologists – The Journal of Dermatology (free)

The world-wide burden of musculoskeletal diseases: a systematic analysis of the World Health Organization Burden of Diseases Database – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentaries: Musculoskeletal conditions now second global cause of years lived with disability – BMJ (free) AND Musculoskeletal conditions 2nd global cause of years with disability – OnMedica (free)

Related Commentary on Twitter

#Musculoskeletal diseases are the second leading cause of years lived with #disability worldwide report @Lupusreference and colleagues in @ARD_BMJ https://t.co/DVdFVJsSyg #MSK pic.twitter.com/yvrQ3dvsTX

— The Lancet Rheumatology (@TheLancetRheum) May 2, 2019

MRI and ultrasound of the hands and wrists in rheumatoid arthritis. Part I: Imaging findings – Skeletal Radiology (free)

MR and ultrasound of the hands and wrists in rheumatoid arthritis. Part II. Added clinical value – Skeletal Radiology (free)

An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) – Seminars in Arthritis and Rheumatism (free)

Management of inflammatory rheumatic conditions in the elderly – Rheumatology (free)

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis–Associated Uveitis – Arthritis & Rheumatology (free)

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non‐Systemic Polyarthritis, Sacroiliitis, and Enthesitis – Arthritis & Rheumatology (free)

A Novel System to Categorize the Symptoms of Systemic Lupus Erythematosus – Arthritis Care & Research (free)

Medication to reduce stomach acid may increase risk of hip fractures – NIHR Signal (free)

Original Article: Proton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies – Osteoporosis International (link to abstract – $ for full-text)

Combined immunosuppressive treatment (CIST) in lupus nephritis: a multicenter, randomized controlled study – Clinical Rheumatology (free)

PANLAR consensus statement on biosimilars – Clinical Rheumatology (free)

Long-Term Drug Therapy and Drug Discontinuations and Holidays for Osteoporosis Fracture Prevention: A Systematic Review – Annals of Internal Medicine (free)

See also: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review – Agency for Healthcare Research and Quality (free) AND Full Report (free PDF) AND Evidence Summary (free PDF)

Comparison of Risk of Osteoporotic Fracture in Denosumab vs Alendronate Treatment Within 3 Years of Initiation – JAMA Network Open (free)

Commentary: No difference in fracture risk with denosumab vs alendronate – Medicine Matters (free)

Gradual tapering TNF inhibitors versus conventional synthetic DMARDs after achieving controlled disease in patients with rheumatoid arthritis: first-year results of the randomised controlled TARA study – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentary: RA flare rates unaffected by tapering strategy – Medwire News (free)

Source: EvidenceAlerts

Diagnosing and treating antiphospholipid syndrome: a consensus paper – The Netherlands Journal of Medicine (free PDF)

Related: Guidelines on the investigation and management of antiphospholipid syndrome – British Journal of Haematology (free)

Exercise as a Prescription for Patients with Various Diseases – Journal of Sport and Health Science (free)

This review summarizes the latest exercise prescription treatments for 26 different diseases.

Prevalence of giant cell arteritis relapse in patients treated with glucocorticoids: a meta‐analysis – Arthritis Care & Research (free PDF)

Current concepts in joint pain in knee osteoarthritis – Der Schmerz (free)

Trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis (TRACE RA): A multicenter, randomized, placebo controlled trial – Arthritis & Rheumatology (free)

Commentaries: Statins safe for rheumatoid arthritis patients – University of Dundee (free) AND Statins safe for preventing cardiovascular events in rheumatoid arthritis patients, study suggests – Wiley (free)

Prevention of complications from use of conventional immunosuppressants: a critical review – Journal of Nephrology (free)

#147 Rheumatoid Arthritis for the Internist – The Curbsiders Internal Medicine Podcast (free audio and summary)

Use of vitamin D drops leading to kidney failure in a 54-year-old man – Canadian Medical Association Journal (free)

“Vitamin D toxicity is rare, but clinicians must be aware of the risks of vitamin D use to limit complications related to hypercalcemia”.

2019 update of the EULAR recommendations for the management of systemic lupus erythematosus – Annals of Rheumatic Diseases (free)

Related Guidelines: Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology – Reumatología Clinica (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus – The Journal of Rheumatology (free PDF)

Pharmacological Management of Osteoporosis in Postmenopausal Women: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free PDF)

News Release: Many postmenopausal women do not receive treatment for osteoporosis (free)

Commentary: Managing Osteoporosis in Postmenopausal Women: An Endocrine Society Guideline – Endocrinology Advisor (free)

See also: Point of Care Algorithm (free)

Evaluating the Erythrocyte Sedimentation Rate – JAMA (free for a limited period)

Neurological Disease in Lupus: Toward a Personalized Medicine Approach – Frontiers in Immunology (free)

Related Reviews: Clinical Features of Neuropsychiatric Syndromes in Systemic Lupus Erythematosus and Other Connective Tissue Diseases (free) AND Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives (free) AND Laboratory and Neuroimaging Biomarkers in Neuropsychiatric Systemic Lupus Erythematosus: Where Do We Stand, Where To Go? (free)

2018 APLAR axial spondyloarthritis treatment recommendations – International Journal of Rheumatic Diseases (free)

Related Guidelines: Spondyloarthritis in over 16s: diagnosis and management – NICE Updated Guideline (free) AND 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis (free) Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force – Annals of Rheumatic Diseases (free)

Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment. – Current Pain and Headache Reports (free)

Diagnosis and Management of Paget’s Disease of Bone in Adults: A Clinical Guideline – Journal of Bone and Mineral Research (free)

Laboratory tests in rheumatology: A rational approach – Cleveland Clinical Journal of Medicine (free)

Source: Hospital Medicine Virtual Journal Club

Swedish Society of Rheumatology 2018 guidelines for investigation, treatment, and follow-up of giant cell arteritis – Scandinavian Journal of Rheumatology (free)

Inclusion body myositis: clinical features and pathogenesis – Nature Reviews Rheumatology (free)

Consensus-based recommendations for the management of juvenile localised scleroderma – Annals of Rheumatic Diseases (free)

Paracetamol versus placebo for knee and hip osteoarthritis – Cochrane Library (free)

Summary: Paracetamol for treating people with hip or knee osteoarthritis – Cochrane Library (free)

Related: Paracetamol: widely used and largely ineffective (free)

Related Commentary on Twitter

New Cochrane Review – 'Paracetamol (acetaminophen) versus placebo for knee and hip osteoarthritis' https://t.co/gGQs23456x @CochraneMSK High‐quality evidence indicated that paracetamol provided only minimal improvements in pain and function for people with hip/knee osteoarthritis

— The Cochrane Library (@CochraneLibrary) February 25, 2019

Relative risk of tuberculosis in patients with rheumatic diseases managed with anti‐tumour necrosis factor‐alpha therapy: A nationwide cohort study – Journal of Clinical Pharmacy and Therapeutics (free)

Commentary: The Risk of Tuberculosis with TNF Inhibitors – RheumNow (free)

Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities – Journal of the American Academy of Dermatology (free)

Commentary: New psoriasis guidelines emphasize management of comorbidities, use of biologics – ACP Internist (free)

Related Guidelines: Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics – Journal of the American Academy of Dermatology (free) AND French guidelines on the use of systemic treatments for moderate‐to‐severe psoriasis in adults – Journal of the European Academy of Dermatology and Venereology (free)

FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat) – U.S. Food & Drug Administration (free)

Commentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)

Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)

IgG4-Related Disease: What A Hematologist Needs To Know – Haematologica (free PDF)

A new decision tree for diagnosis of osteoarthritis in primary care: international consensus of experts – Aging Clinical and Experimental Research (free)

From Systemic Inflammation to Neuroinflammation: The Case of Neurolupus – International Journal of Molecular Sciences (free)

Sjögren’s syndrome and systemic lupus erythematosus: links and risks – Open Access Rheumatology: Research and Reviews (free)

Enthesitis-related arthritis: current perspectives – Open Access Rheumatology: Research and Reviews (free)

Effect of Magnetic Resonance Imaging vs Conventional Treat-to-Target Strategies on Disease Activity Remission and Radiographic Progression in Rheumatoid Arthritis: The IMAGINE-RA Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Rheumatoid Arthritis: Study Finds No Benefit to MRI-Guided Treatment – MedicalResearch.com (free) AND MRI-guided treatment strategy unnecessary for RA in clinical remission – Medwire News (free)

Mycophenolate mofetil versus cyclophosphamide for remission induction in ANCA-associated vasculitis: a randomised, non-inferiority trial – Annals of Rheumatic Diseases (link to abstract – $ for full-text)

Commentary: Randomized data back EULAR guidelines for mycophenolate mofetil use in AAV – Medwire News (free)

Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline – The BMJ (free)

Commentaries: Expert panel strongly recommends against surgery for the most common shoulder pain – MedicalXpress (free) AND Guidelines Recommend Against Surgery for Subacromial Pain Syndrome – NEJM Journal Watch (free)

Related Systematic Reviews: Subacromial decompression surgery for adults with shoulder pain: a systematic review with meta-analysis – British Journal of Sports Medicine (free) AND Subacromial Decompression Surgery for Rotator Cuff Disease – Cochrane Library (link to study and randomized trials on the subject)

Fetal Toxicity of Immunosuppressive Drugs in Pregnancy – Journal of Clinical Medicine (free)

Position article and guidelines 2018 recommendations of the Brazilian Society of Rheumatology for the indication, interpretation and performance of nailfold capillaroscopy – Advances in Rheumatology (free)

Interstitial Lung Disease and Other Pulmonary Manifestations in Connective Tissue Diseases – Mayo Clinic Proceedings (free)

Central Nervous System Involvement in ANCA-Associated Vasculitis: What Neurologists Need to Know – Frontiers in Neurology (free)

Guidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathies – Advances in Rheumatology (free)

Management and treatment of glomerular diseases (part 1): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)

Part 2: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)

Related: See All KDIGO Guidelines (all free)

Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology – Reumatología Clinica (free for a limited period)

Related Guidelines: The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus (free)

Related Reviews: Systemic Lupus Erythematosus in Primary Care: An Update and Practical Messages for the General Practitioner (free) AND Infection in systemic lupus erythematosus, similarities, and differences with lupus flare (free)

Comparative Clinical Effectiveness of Nonsurgical Treatment Methods in Patients With Lumbar Spinal Stenosis: A Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Lumbar Spinal Stenosis: Non-Surgical Options Compared – MedicalResearch.com (free)

Interstitial lung disease associated with systemic sclerosis (SSc-ILD) – Respiratory Research (free)

Exercise-induced hypoalgesia: A meta-analysis of exercise dosing for the treatment of chronic pain – PLOS One (free)

Subacromial decompression surgery for rotator cuff disease – Cochrane Library (free)

Summary: Surgery for rotator cuff disease (free)

Related Studies: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement (free study and commentaries) AND Arthroscopic subacromial decompression for subacromial shoulder pain (free study and commentaries)

“The data in this review do not support the use of subacromial decompression in the treatment of rotator cuff disease manifest as painful shoulder impingement.”

Multidisciplinary recommendations for diagnosis and treatment of foot problems in people with rheumatoid arthritis – Journal of Foot and Ankle Research (free)

Proton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies – Osteoporosis International (link to abstract – $ for full-text)

Commentary: PPIs up risk for hip fracture in large meta-analysis – Univadis (free registration required)

Related Commentary on Twitter

Metanalysis of 24 PPI studies, 319,568 hip fracture pts, suggests PPIs associated with a greater risk of hip fracture (RR 1.20, 95% CI 1.14–1.28, p < 0.0001) and may be greater with higher dose (RR 1.30, 95% CI 1.20–1.40, p < 0.0001). https://t.co/nbiEIPRaXg

— Dr. John Cush (@RheumNow) December 17, 2018

Korean Guideline for the Prevention and Treatment of Glucocorticoid-induced Osteoporosis – Journal of Bone Metabolism (free)

Related: 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis (free)

Update of the evidence based, interdisciplinary guideline for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis – Seminars in Arthritis and Rheumatism (free)

Adrenal insufficiency in systematic lupus erythematosus (SLE) and antiphospholipid syndrome (APS): A systematic review – Autoimmunity Reviews (free)

Guidelines for biomarkers in autoimmune rheumatic diseases – evidence based analysis – Autoimmunity Reviews (free)

Diagnostic performance of temporal artery ultrasound for the diagnosis of giant cell arteritis: a systematic review and meta-analysis of the literature – Autoimmunity Reviews (free)

Scleroderma Renal Crisis: Not so easy to diagnose and manage… – emDocs (free)

Chronic low back pain and postural rehabilitation exercise: a literature review – Journal of Pain Research (free)

Physical Therapy Approaches in the Treatment of Low Back Pain – Pain and Therapy (free)

Antiphospholipid Syndrome and the Neurologist: From Pathogenesis to Therapy – Frontiers in Neurology (free)

Carpal tunnel syndrome (CTS): a look at the evidence for treatments – Evidently Cochrane Blog (free)

Novel Treatments in Lupus – Frontiers in Immunology (free)

Comorbidities in polymyalgia rheumatica: a systematic review – Arthritis Research & Therapy (free)

Oral manifestations of autoimmune connective tissue diseases – Indian Journal of Rheumatology (free)

2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis – Arthritis Care & Research (free)

The Use of Vitamins and Minerals in Skeletal Health: American Association of Clinical Endocrinologists and The American College Of Endocrinology Position Statement (free PDF)

Commentary: AACE statement questions efficacy of dietary supplements for bone health – Healio (free registration required)

AAPT Diagnostic Criteria for Fibromyalgia – The Journal of Pain (free)

Related Guidelines: EULAR revised recommendations for the management of fibromyalgia (free) AND Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: Executive summary (free)

Assessing Disease Activity in Psoriatic Arthritis: A Literature Review – Rheumatology and Therapy (free)

Audiovestibular Symptoms in Systemic Autoimmune Diseases – Journal of Immunology Research (free)

Vaccination Guidelines for Patients With Immune-Mediated Disorders on Immunosuppressive Therapies – Journal of Cutaneous Medicine and Surgery (free)

Musculoskeletal and Rheumatic Diseases Induced by Immune Checkpoint Inhibitors: A Review of the Literature – Current Drug Safety (free)

The Challenges of Approaching and Managing Gout – Rheumatic Disease Clinics of North America (free)

Update on Vertigo in Autoimmune Disorders, from Diagnosis to Treatment – Journal of Immunology Research (free)

Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials – Rheumatology (free)

Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk – Cardiology Journal (free PDF)

The Vasculopathy of Juvenile Dermatomyositis – Frontiers in Pediatrics (free)

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial – The Lancet (free)

Invited Commentary: Steroid injection or wrist splint for first-time carpal tunnel syndrome? (free)

“A single corticosteroid injection shows superior clinical effectiveness at 6 weeks compared with night-resting splints, making it the treatment of choice for rapid symptom response in mild or moderate carpal tunnel syndrome presenting in primary care.”

Association of Depression With Risk of Incident Systemic Lupus Erythematosus in Women Assessed Across 2 Decades – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Depression May Increase Risk of Developing an Autoimmune Disease – MedicalResearch.com (free) AND Depression Tied to Double the Risk for Lupus in Women – Medscape (free registration required)

Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts – The BMJ (free)

Editorial: The role of diet in serum urate concentration (free)

Commentary: Diet Might Play Less of a Role in Gout Than Previously Thought – Physician’s First Watch (free)

Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: The Lancet Diabetes & Endocrinology: Vitamin D supplementation in adults does not prevent fractures, falls or improve bone mineral density – The Lancet (free) AND Vitamin D supplements don’t help bone health, major study concludes – The Guardian (free) AND Millions of Americans take vitamin D. Most should just stop – VOX (free)

Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline) AND Vitamin D Not Linked to Fracture Risk (free study and commentaries)

Effect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears: The ESCAPE Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: PT an Alternative to Surgery for Some Meniscal Tears – Physician’s First Watch (free)

Related: Adverse Outcomes After Arthroscopic Partial Meniscectomy (free study, commentary and guideline on the subject)

“Our Dutch multi center RCT demonstrates noninferiority of physical therapy compared with early surgery with arthroscopic partial meniscectomy for improving self-reported knee function in patients with nonobstructive meniscal tears.” (via @RudolfPoolman see Tweet)

Fracture Prevention with Zoledronate in Older Women with Osteopenia – New England Journal of Medicine (free)

Editorial: A Not-So-New Treatment for Old Bones (free)

Commentary: Study Suggests More Older Women May Benefit From Bone Drugs – The Associated Press (free)

Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Low-dose antidepressants ease back pain – Australian Hospital + Healthcare Bulletin (free) AND Antidepressant Amitriptyline Might Help Ease Low Back Pain – Physician’s First Watch (free)

Pulmonary vasculitis – Journal of Thoracic Disease (free)