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Systematic Reviews & Meta-analysis

Population-level risks of alcohol consumption by amount, geography, age, sex, and year | A systematic analysis for the Global Burden of Disease Study 2020.

18 Jul, 2022 | 11:39h | UTC

Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020 – The Lancet

News Release: Alcohol consumption carries significant health risks and no benefits for young people; some older adults may benefit from drinking a small amount of alcohol – Institute for Health Metrics and Evaluation

Commentaries:

Alcohol is never good for people under 40, global study finds – The Guardian

Global study finds surprising results for alcohol consumption – CNN

No alcohol safe to drink, global study confirms – BBC

 

Commentary on Twitter (thread – click for more)

 


Network M-A | Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults.

18 Jul, 2022 | 11:41h | UTC

Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis – The Lancet

Commentary: Expert reaction to systematic review and network meta-analysis of medication for acute and long-term insomnia – Science Media Centre

 


Incidence, risk factors, natural history, and hypothesized mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review.

18 Jul, 2022 | 11:30h | UTC

Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review – The BMJ

News Release: New study updates evidence on rare heart condition after covid vaccination – BMJ Newsroom

 


Network M-A | Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer.

18 Jul, 2022 | 11:27h | UTC

Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer: a systematic review and network meta-analysis – The Lancet Oncology

 

Commentary on Twitter

 


M-A | Mid- to long-term clinical and echocardiographic effects of post-procedural permanent pacemaker implantation after transcatheter aortic valve replacement.

18 Jul, 2022 | 11:10h | UTC

Mid- to Long-Term Clinical and Echocardiographic Effects of Post-procedural Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis – Frontiers in Cardiovascular Medicine

 


Relationship between low-density lipoprotein cholesterol, lipid-lowering agents and risk of stroke: a meta-analysis of observational studies (n = 355,591) and randomized controlled trials (n = 165,988).

18 Jul, 2022 | 11:09h | UTC

Relationship between low-density lipoprotein cholesterol, lipid-lowering agents and risk of stroke: a meta-analysis of observational studies (n = 355,591) and randomized controlled trials (n = 165,988) – Archives of Medical Sciences

 


M-A of RCTs | Efficacy of corticosteroids for hand osteoarthritis.

18 Jul, 2022 | 11:07h | UTC

Efficacy of corticosteroids for hand osteoarthritis – a systematic review and meta-analysis of randomized controlled trials – BMC Musculoskeletal Disorders

 


M-A of RCTs | Efficacy and safety of potassium-competitive acid blockers versus proton pump inhibitors as Helicobacter pylori eradication therapy.

18 Jul, 2022 | 11:03h | UTC

Efficacy and safety of potassium-competitive acid blockers versus proton pump inhibitors as Helicobacter pylori eradication therapy: a meta-analysis of randomized clinical trials – Clinics

 


Systematic Review | Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia.

15 Jul, 2022 | 12:47h | UTC

Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia – Cochrane Library

Summary: Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia – Cochrane Library

 

Commentary on Twitter

 


Systematic Review | Vagus nerve stimulation for focal seizures

15 Jul, 2022 | 12:45h | UTC

Vagus nerve stimulation for focal seizures – Cochrane Library

Summary: Vagus nerve stimulation for focal seizures – Cochrane Library

 


Pressure ulcers (pressure injuries) | Cochrane Library evidence and resources.

14 Jul, 2022 | 13:03h | UTC

Pressure ulcers (pressure injuries): evidence and resources – Evidently Cochrane

 


M-A | Vortioxetine for the treatment of major depressive disorder in adults.

15 Jul, 2022 | 12:15h | UTC

Systematic Review and Meta-Analysis of Vortioxetine for the Treatment of Major Depressive Disorder in Adults – Frontiers in Psychiatry

 


Systematic Review | Anti‐IL‐5 therapies for asthma.

14 Jul, 2022 | 12:40h | UTC

Anti‐IL‐5 therapies for asthma – Cochrane Library

Summary: Mepolizumab, reslizumab or benralizumab for people already taking inhaled steroids and long-acting beta 2-agonists for their asthma – Cochrane Library

 


M-A | Risk of developing gallbladder cancer in patients with gallbladder polyps detected on Trans-Abdominal ultrasound.

14 Jul, 2022 | 12:14h | UTC

Risk of developing gallbladder cancer in patients with gallbladder polyps detected on Trans-Abdominal ultrasound: a systematic review and Meta-Analysis – British Journal of Radiology (link to abstract – $ for full-text)

Related:

Critical Analysis of the Updated Guidelines for Management of Gallbladder Polyps – Annals of Surgical Oncology (if the link is paywalled, try this one)

Guideline: Management and follow-up of gallbladder polyps – “If the patient has no risk factors for malignancy, and a gallbladder polypoid lesion of 5 mm or less, follow-up is not required”.

 


M-A | Home oxygen for moderate hypoxemia in chronic obstructive pulmonary disease.

13 Jul, 2022 | 11:47h | UTC

Home oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Risk factors of delirium in pediatric intensive care units.

13 Jul, 2022 | 11:35h | UTC

Risk factors of delirium in paediatric intensive care units: A meta-analysis – PLOS One

 


M-A | The effect of fiber supplementation on chronic constipation in adults.

13 Jul, 2022 | 11:30h | UTC

The effect of fiber supplementation on chronic constipation in adults: an updated systematic review and meta-analysis of randomized controlled trials – The American Journal of Clinical Nutrition

 


Network M-A | Treatment of idiopathic membranous nephropathy for moderate or severe proteinuria.

13 Jul, 2022 | 11:16h | UTC

Treatment of Idiopathic Membranous Nephropathy for Moderate or Severe Proteinuria: A Systematic Review and Network Meta-Analysis – International Journal of Clinical Practice

Related Cochrane Review:

Summary: Immunosuppressive treatment for adults with idiopathic membranous nephropathy – Cochrane Library

Original Study: Immunosuppressive treatment for primary membranous nephropathy in adults with nephrotic syndrome – Cochrane Library

 


M-A | Oral iron supplementation in patients with heart failure.

13 Jul, 2022 | 11:17h | UTC

Oral iron supplementation in patients with heart failure: a systematic review and meta-analysis – ESC Heart Failure

 


M-A | Dual-hormone artificial pancreas for glucose control in type 1 diabetes.

13 Jul, 2022 | 11:19h | UTC

Dual-hormone artificial pancreas for glucose control in type 1 diabetes: A meta-analysis – Diabetes, Obesity and Metabolism

 


M-A | Global changes in child and adolescent physical activity during the COVID-19 pandemic.

12 Jul, 2022 | 12:53h | UTC

Global Changes in Child and Adolescent Physical Activity During the COVID-19 Pandemic: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)

 


M-A | Does it really pay-off? Comparison of lymphadenectomy versus observational approach in skin melanoma with positive sentinel node biopsy.

12 Jul, 2022 | 12:37h | UTC

Does It Really Pay-Off? Comparison of Lymphadenectomy versus Observational Approach in Skin Melanoma with Positive Sentinel Node Biopsy: Systematic Review and Meta-Analysis – Journal of Clinical Medicine

 


M-A | Factors correlated with physical function 1 year after total knee arthroplasty in patients with knee osteoarthritis.

12 Jul, 2022 | 12:24h | UTC

Factors Correlated With Physical Function 1 Year After Total Knee Arthroplasty in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


Brain stimulation may reduce negative symptoms of schizophrenia, meta-analysis suggests.

12 Jul, 2022 | 11:56h | UTC

Brain Stimulation May Reduce Negative Symptoms of Schizophrenia, Meta-Analysis Suggests – Psychiatric News Alert

Original Study: Assessment of Noninvasive Brain Stimulation Interventions for Negative Symptoms of Schizophrenia: A Systematic Review and Network Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)

Author Interview: Assessment of Noninvasive Brain Stimulation Interventions for Negative Symptoms of Schizophrenia

 


Network M-A | Effects of therapies for Ebola virus disease.

12 Jul, 2022 | 11:45h | UTC

Effects of therapies for Ebola virus disease: a systematic review and network meta-analysis – The Lancet Microbe

 


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