Systematic Reviews & Meta-analysis
Systematic Review | Probiotics’ potential in preventing necrotizing enterocolitis in very preterm, VLBW infants warrants further research
31 Jul, 2023 | 13:51h | UTC
RCT | Combined endovenous ablation and compression speeds up venous leg ulcers healing
31 Jul, 2023 | 13:49h | UTCEndovenous ablation for venous leg ulcers – Cochrane Library
M-A | P2Y12 monotherapy after 1-3 months DAPT safely reduces bleeding in PCI patients with CAD and CKD
26 Jul, 2023 | 13:18h | UTCRelated:
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis – Nature Reviews Cardiology (if the link is paywalled, try this one)
Long-term Effects of P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention: 3-Year Follow-up of the SMART-CHOICE Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)
M-A | Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals
26 Jul, 2023 | 13:15h | UTCCommentary: M-A: Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals – HCP Live
M-A | Oral isotretinoin and triple topical therapies found most effective in acne vulgaris treatment
26 Jul, 2023 | 13:13h | UTC
M-A | Early initiation of renal replacement therapy fails to improve survival rates in AKI patients
25 Jul, 2023 | 13:46h | UTC
Systematic Review | Rapamycin and rapalogs for tuberous sclerosis complex
25 Jul, 2023 | 13:43h | UTCRapamycin and rapalogs for tuberous sclerosis complex – Cochrane Library
M-A | Early NIPPV likely reduces the risk of respiratory failure and intubation in very preterm infants
25 Jul, 2023 | 13:39h | UTC
Systematic Review | Existing research on post-stroke depression interventions lacks conclusive results
25 Jul, 2023 | 13:37h | UTC
M-A | Comparison of systemic treatments for chronic plaque psoriasis – Anti-IL17 stands out
25 Jul, 2023 | 13:27h | UTC
Systematic Review | Low-level HIV viremia (below 1000 copies/mL) linked to minimal sexual transmission risk
24 Jul, 2023 | 13:15h | UTCThe risk of sexual transmission of HIV in individuals with low-level HIV viraemia – The Lancet
Editorial: HIV is sexually untransmittable when viral load is undetectable – The Lancet
Related: Study: Growing Acceptability of “Undetectable = Untransmittable” but Widespread Misunderstanding of HIV Transmission Risk Persists (several texts on the subject)
Commentary on Twitter
People on ART with low but detectible levels of HIV viral load have almost zero risk of sexually transmitting the virus to others, in-depth review suggests #IAS2023https://t.co/wU26C8cEMK pic.twitter.com/hQHLDqPxO6
— The Lancet (@TheLancet) July 22, 2023
Systematic Review | Dual therapy of Rifaximin and lactulose potentially reduces risk in hepatic encephalopathy
24 Jul, 2023 | 12:57h | UTC
Systematic Review | Insufficient evidence for ACEi/ARB’s impact on early non-diabetic CKD
24 Jul, 2023 | 12:56h | UTC
Systematic Review | Medical treatment of eosinophilic esophagitis
21 Jul, 2023 | 13:27h | UTCMedical treatment of eosinophilic esophagitis – Cochrane Library
Summary: Medical treatments for eosinophilic esophagitis – Cochrane Library
Related:
M-A | Efficacy of elimination diets in eosinophilic esophagitis
RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis
Systematic Review | Platinum doublet therapy outperforms non-platinum for advanced NSCLC, performance status 2 patients
20 Jul, 2023 | 10:56h | UTC
M-A | Adverse effects of antipsychotics on sleep in patients with schizophrenia
18 Jul, 2023 | 13:45h | UTC
M-A | One-year usage of elastic compression stockings comparable to two for post-thrombotic syndrome prevention
17 Jul, 2023 | 13:49h | UTC
Systematic Review | Criteria to achieve safe antimicrobial intravenous-to-oral switch in hospitalized adult populations
17 Jul, 2023 | 13:34h | UTC
M-A | First-line thiazide diuretics show reduced cardiovascular events, comparable mortality vs. other antihypertensive drugs
14 Jul, 2023 | 12:55h | UTC
M-A | Drug therapies for treatment of idiopathic pulmonary fibrosis
14 Jul, 2023 | 12:40h | UTC
A guide and pragmatic considerations for applying GRADE to network meta-analysis
12 Jul, 2023 | 13:44h | UTCA guide and pragmatic considerations for applying GRADE to network meta-analysis – The BMJ
Commentary on Twitter
How can you assess the certainty of evidence from network meta-analyses using the GRADE approach?
A new guide with practical strategies ?https://t.co/g2S4a17GM7 pic.twitter.com/FHZOSDN0b8
— The BMJ (@bmj_latest) July 2, 2023
M-A | Cognitive rehabilitation may improve everyday activities in mild to moderate dementia
12 Jul, 2023 | 13:34h | UTCCognitive rehabilitation for people with mild to moderate dementia – Cochrane Library
M-A | P2Y12 inhibitors show superior efficacy over aspirin for secondary prevention in CAD
11 Jul, 2023 | 14:06h | UTCP2Y12 Inhibitor or Aspirin Monotherapy for Secondary Prevention of Coronary Events – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Related:
Monotherapy with a P2Y12 inhibitor or aspirin for secondary prevention in patients with established atherosclerosis: a systematic review and meta-analysis – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Given superior efficacy & similar overall safety, #P2Y12 inhibitor monotherapy might be preferred over #aspirin monotherapy for long-term secondary prevention in pts w/ established #cvCAD. https://t.co/EehIEuWqOt#JACC #P2Y12i #CardioTwitter @FeliceGragnano @vlgmrc @Drroxmehran pic.twitter.com/betLycXGs5
— JACC Journals (@JACCJournals) July 5, 2023
M-A | Catheter-directed thrombolysis vs. systemic thrombolysis and anticoagulation in intermediate- or high-risk pulmonary embolism
11 Jul, 2023 | 13:47h | UTC
M-A | Efficacy of varenicline versus bupropion for smoking cessation
10 Jul, 2023 | 13:23h | UTC