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Systematic Reviews & Meta-analysis

M-A | The effect of curcumin supplementation on weight loss and anthropometric indices

27 Mar, 2023 | 13:04h | UTC

The effect of curcumin supplementation on weight loss and anthropometric indices: an umbrella review and updated meta-analyses of randomized controlled trials – American Journal of Clinical Nutrition

 


Trends of randomized clinical trials citing prior systematic reviews, 2007-2021

27 Mar, 2023 | 12:56h | UTC

Trends of Randomized Clinical Trials Citing Prior Systematic Reviews, 2007-2021 – JAMA Network Open

Invited Commentary: Should a Systematic Review Be Required in a Clinical Trial Report? Perhaps, But Not Yet – JAMA Network Open

 

Commentary on Twitter

 


M-A | Efficacy of intraosseous access for trauma resuscitation

23 Mar, 2023 | 12:52h | UTC

Efficacy of intraosseous access for trauma resuscitation: a systematic review and meta-analysis – World Journal of Emergency Surgery

 


M-A | Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis

23 Mar, 2023 | 12:50h | UTC

Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis – The Lancet Child & Adolescent Health

News Release: New Algorithms Could Improve Pediatric Tuberculosis Diagnosis – Yale School of Public Health

 

Commentary from the author on Twitter (thread – click for more)

 


M-A | Effects of dairy intake on markers of cardio-metabolic health in adults

23 Mar, 2023 | 12:35h | UTC

Effects of dairy intake on markers of cardio-metabolic health in adults – a systematic review with network meta-analysis – Advances in Nutrition

 

Commentary on Twitter

 


M-A | eHealth-based psychosocial interventions for adults with insomnia

23 Mar, 2023 | 12:31h | UTC

eHealth-Based Psychosocial Interventions for Adults With Insomnia: Systematic Review and Meta-analysis of Randomized Controlled Trials – Journal of Medical Internet Research

 


M-A | Intravenous vitamin C in sepsis and septic shock – no influence on mortality outcomes

22 Mar, 2023 | 13:23h | UTC

The outcome of IV vitamin C therapy in patients with sepsis or septic shock: a meta-analysis of randomized controlled trials – Critical Care

Related:

Early administration of hydrocortisone, vitamin C, and thiamine in adult patients with septic shock: a randomized controlled clinical trial – Critical Care

Parenteral Vitamin C in Patients with Severe Infection: A Systematic Review – NEJM Evidence

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit – New England Journal of Medicine

Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis – Intensive Care Medicine

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA

 


M-A | Posterior pericardiotomy reduces the risk of atrial fibrillation after cardiac surgery

22 Mar, 2023 | 13:18h | UTC

Posterior pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: a systematic review and meta-analysis of 25 randomised controlled trials – EuroIntervention (link to abstract – $ for full-text)

Related:

Effect of posterior pericardiotomy in cardiac surgery: A systematic review and meta-analysis of randomized controlled trials – Frontiers in Cardiovascular Medicine

The Role of the Posterior Left Pericardiotomy in Reducing Pericardial Effusion and Postoperative Atrial Fibrillation After Cardiac Surgery – American College of Cardiology

Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial – The Lancet

 


M-A | Maternal and neonatal complications following Kielland’s rotational forceps delivery

22 Mar, 2023 | 13:17h | UTC

Maternal and neonatal complications following Kielland’s rotational forceps delivery: A systematic review and meta-analysis – BJOG

 


M-A | Comparison of mental health symptoms before and during the covid-19 pandemic

21 Mar, 2023 | 13:40h | UTC

Comparison of mental health symptoms before and during the covid-19 pandemic: evidence from a systematic review and meta-analysis of 134 cohorts – The BMJ

Editorial: Mental health and the covid-19 pandemic – The BMJ

News Release: Study suggests little deterioration in mental health linked to the pandemic – BMJ Newsroom

Commentaries:

A patient’s perspective on mental health and the pandemic – The BMJ

Expert reaction to systematic review and meta-analysis on mental health before and during the COVID-19 pandemic – Science Media Centre

World’s most comprehensive study on COVID-19 mental health – McGill University

 


SR | Topical antibiotics modestly improve resolution of acute bacterial conjunctivitis

21 Mar, 2023 | 13:33h | UTC

Summary: The Cochrane Review evaluated the benefits and potential side effects of antibiotic therapy in treating acute bacterial conjunctivitis. The authors included 21 randomized controlled trials, with a total of 8,805 participants. The trials evaluated the effectiveness of topical antibiotic treatments in the form of drops or ointments, and were heterogeneous in terms of eligibility criteria, antibiotic drug class, duration of treatment, and outcomes assessed.

The review found that antibiotics likely improved clinical cure by 26% compared with placebo, with no evidence of serious systemic side effects reported in either the antibiotic or placebo group. Fluoroquinolones were found to have fewer ocular side effects compared to non-fluoroquinolones.

Overall, the review suggests that the use of topical antibiotics may be considered to achieve better clinical and microbiologic efficacy than placebo in treating acute bacterial conjunctivitis.

Article: Antibiotics versus placebo for acute bacterial conjunctivitis – Cochrane Library

Summary: What are the benefits and harms of antibiotics for acute bacterial conjunctivitis? – Cochrane Library

 


SR | Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants

21 Mar, 2023 | 13:14h | UTC

Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants – Cochrane Library

Summary: Different timing and dosages of corticosteroids to prevent lung injury – Cochrane Library

 


SR | Postnatal phenobarbital for the prevention of intraventricular hemorrhage in preterm infants

21 Mar, 2023 | 13:15h | UTC

Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm infants – Cochrane Library

Summary: What are the benefits and risks of phenobarbital for preventing bleeding to the brain in babies born too early? – Cochrane Library

 

Commentary on Twitter

 


M-A | Analgesic effect of erector spinae plane block in adults undergoing laparoscopic cholecystectomy

21 Mar, 2023 | 13:06h | UTC

Analgesic effect of erector spinae plane block in adults undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized controlled trials – BMC Anesthesiology

 


COVID-19-associated mucormycosis | A systematic review and meta-analysis of 958 cases

20 Mar, 2023 | 13:43h | UTC

COVID-19-associated mucormycosis: A systematic review and meta-analysis of 958 cases – Clinical Microbiology and Infection

 


M-A | Has the therapeutical ceiling been reached in Crohn’s disease randomized controlled trials?

17 Mar, 2023 | 12:55h | UTC

Has the therapeutical ceiling been reached in Crohn’s disease randomized controlled trials? A systematic review and meta-analysis – UEG Journal

 


M-A | Health effects of the time-restricted eating in adults with obesity

17 Mar, 2023 | 12:54h | UTC

Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis – Frontiers in Nutrition

Related:

Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial – Cell Metabolism

Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults With Obesity: A Randomized Clinical Trial – JAMA Internal Medicine

Effects of Intermittent Fasting in Human Compared to a Non-intervention Diet and Caloric Restriction: A Meta-Analysis of Randomized Controlled Trials – Frontiers in Nutrition

Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition

Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine

Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open

 


SR | Planned hospital birth compared with planned home birth for pregnant women at low risk of complications

17 Mar, 2023 | 12:51h | UTC

Planned hospital birth compared with planned home birth for pregnant women at low risk of complications – Cochrane Library

Summary: Planned hospital birth versus planned home birth – Cochrane Library

 


M-A | Prevalence of perinatal depression in low- and middle-income countries

17 Mar, 2023 | 12:49h | UTC

Prevalence of Perinatal Depression in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis – JAMA Psychiatry

 

Commentary on Twitter

 


M-A | Low-intensity follow-up after cancer surgery does not reduce patient satisfaction or well-being

16 Mar, 2023 | 13:10h | UTC

Oncological surgery follow-up and quality of life: meta-analysis – British Journal of Surgery

 


M-A | Active fluid de-resuscitation in critically ill patients with septic shock

16 Mar, 2023 | 13:09h | UTC

Active fluid de-resuscitation in critically ill patients with septic shock: A systematic review and meta-analysis – European Journal of Internal Medicine

 


M-A | Endoscopic surgery for spontaneous supratentorial intracerebral hemorrhage

16 Mar, 2023 | 13:04h | UTC

Endoscopic surgery for spontaneous supratentorial intracerebral haemorrhage: A systematic review and meta-analysis – Frontiers in Neurology

 


Deprescribing strategies for opioids and benzodiazepines with emphasis on concurrent use: a scoping review

15 Mar, 2023 | 15:06h | UTC

Deprescribing Strategies for Opioids and Benzodiazepines with Emphasis on Concurrent Use: A Scoping Review – Journal of Clinical Medicine

Related:

An Overview of Systematic Reviews and Meta-Analyses on the Effect of Medication Interventions Targeting Polypharmacy for Frail Older Adults – Journal of Clinical Medicine

Physician-led medication reviews in polypharmacy patients treated with at least 12 medications in a type 2 diabetes outpatient clinic: a randomised trial – Diabetic Medicine

RCT | A deprescribing intervention reduced medication burden among older adults in post-acute care

Achieving sustainable healthcare through deprescribing of unnecessary medications: making sense of the evidence – Cochrane Library

Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis – Health Technology Assessment

Barriers and facilitators to deprescribing of cardiovascular medications: a systematic review – BMJ Open

A National Modified Delphi Consensus Process to Prioritize Experiences and Interventions for Antipsychotic Medication Deprescribing Among Adult Patients With Critical Illness – Critical Care Explorations

Deprescribing proton pump inhibitors – Australian Journal of General Practice

Medication reviews and deprescribing as a single intervention in falls prevention: a systematic review and meta-analysis – Age and Ageing

Optimizing Medication Use in Older Adults With Rheumatic Musculoskeletal Diseases: Deprescribing as an Approach When Less May Be More – ACP Open Rheumatology

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy – European Heart Journal – Cardiovascular Pharmacotherapy

Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology

Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology

Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports

How-to guide for medication reviews in older adults with cancer: A Young International Society of Geriatric Oncology and Nursing & Allied Health Interest Group initiative – Journal of Geriatric Oncology

Deprescribing in Palliative Cancer Care – Life

Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360

Process evaluation of implementation strategies to reduce potentially inappropriate medication prescribing in older population: A scoping review – Research in Social and Administrative Pharmacy

AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review – Gastroenterology

Development of a Metric to Detect and Decrease Low-Value Prescribing in Older Adults – JAMA Network Open

The MedSafer Study—Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial – JAMA Internal Medicine

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines – Supportive Care in Cancer

Prescribing practices, patterns, and potential harms in patients receiving palliative care: A systematic scoping review – Exploratory Research in Clinical and Social Pharmacy

A narrative review of evidence to guide deprescribing among older adults – Journal of General and Family Medicine

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens – The Lancet Health Longevity

Polypharmacy Management in Older Patients – Mayo Clinic Proceedings

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt international

Eliminating Medication Overload: A National Action Plan – Lown Institute

International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action – Drugs & Aging

Common ED Medication Errors: Polypharmacy – emDocs

Current and future perspectives on the management of polypharmacy – BMC Family Practice

Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety

Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international

Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety

 


M-A | Risk of recurrence and reintervention after uterine-sparing interventions for symptomatic adenomyosis

15 Mar, 2023 | 15:05h | UTC

Risk of Recurrence and Reintervention After Uterine-Sparing Interventions for Symptomatic Adenomyosis: A Systematic Review and Meta-Analysis – Obstetrics & Gynecology

 


Proposed triggers for retiring a living systematic review

15 Mar, 2023 | 15:02h | UTC

Proposed triggers for retiring a living systematic review – BMJ Evidence-Based Medicine

 


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