Systematic Reviews

Surgery for rotator cuff tears – Cochrane Library (free)

Summary: Does repair of torn rotator cuff tendons work? – Cochrane Library (free)

Related: BMJ Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain Does Not Improve Outcomes (free guideline and other resources)

 

Related Commentary on Twitter

 


Effectiveness of management strategies for uninvestigated dyspepsia: systematic review and network meta-analysis – The BMJ (free)

Commentary: Managing Dyspepsia with “Test and Treat” Ranked Best Strategy – NEJM Journal Watch (free)

 

Related Commentary on Twitter

 


Cochrane Sustainable Healthcare: evidence for action on too much medicine – Cochrane Library (free)

News Release: Launch of new Cochrane Sustainable Healthcare Field – Cochrane Library (free)

See Website: Cochrane Sustainable Healthcare (free)

 

Related Commentary on Twitter

 


Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery – Cochrane Library (free)

Summary: Preventing pain after brain surgery – Cochrane Library (free)

 

Related Commentary on Twitter

 


Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Bedside optic nerve ultrasonography may be useful for measuring intracranial pressure – ACP Hospitalist (free) AND Optic Nerve Ultrasound May ID Increased Intracranial Pressure – Physician’s Briefing (free)

 

Related Commentary on Twitter

 


Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis – British Journal of Sports Medicine (free)

 

Related Commentary on Twitter

 


Valproate for acute mania – Cochrane Library (free)

Summary: Valproate for acute mania  – Cochrane Library (free)

 

Related Commentary on Twitter

 


Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy – JACC CardioOncology (free)

 

Related Commentary on Twitter

 


Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Meta-Analysis of TAVR vs. SAVR in Low-Risk Patients – American College of Cardiology (free) AND TAVR Survival Surpasses SAVR in Low-Risk Patients: Meta-analysis – Medscape (free registration required)

“The one clear unknown that everyone points to is valve durability” (form Medscape)

“longer follow-up regarding valve degeneration will be needed to confirm TAVR as the preferred treatment for low-risk patients with severe AS.” (from American College of Cardiology)

 


Antiviral treatment for Bell’s palsy (idiopathic facial paralysis) – Cochrane Library (free)

Summary: Antiviral treatment for Bell’s palsy – Cochrane Library (free)

“The combination of antivirals and corticosteroids may have little or no effect on rates of incomplete recovery in comparison to corticosteroids alone”

 


Altering the availability or proximity of food, alcohol, and tobacco products to change their selection and consumption – Cochrane Library (free)

Summary: Altering the availability or proximity of food, alcohol, and tobacco products to change their selection and consumption – Cochrane Library (free)

 

Related Commentary on Twitter

 


Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection – Cochrane Library (free)

Summary: Bathing critically ill patients with chlorhexidine to prevent hospital-acquired infections – Cochrane Library (free)

“Due to the very low-certainty evidence available, it is not clear whether bathing with chlorhexidine reduces hospital-acquired infections, mortality, or length of stay in the ICU”

 


Early Experience With Transcatheter Mitral Valve Replacement: A Systematic Review – Journal of the American Heart Association (free)

“TMVR was a feasible, less invasive alternative for treating severe mitral regurgitation in patients with high or prohibitive surgical risk”

 


Effects of maternal influenza vaccination on adverse birth outcomes: A systematic review and Bayesian meta-analysis – PLOS One (free)

Related Research: Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers (free)

Related ACOG Guideline: Influenza Vaccination During Pregnancy (free)

“maternal influenza vaccination is not associated with harmful effects on birth outcomes. The beneficial effects reported from previous studies on preterm birth, low birth weight, and fetal death could not be confirmed.”

 


Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


The efficacy and safety of inhaled antibiotics for the treatment of bronchiectasis in adults: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ (free)

Related: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)

Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.

 

Related Commentary on Twitter

 


Medications Affecting the Biochemical Conversion to Type 2 Diabetes: A Systematic Review and Meta-Analysis – The Journal of Clinical Endocrinology & Metabolism (free)

α-Glucosidase inhibitors, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, metformin, orlistat, phentermine/topiramate, and pioglitazone significantly reduced the risk of biochemical conversion to T2DM, whereas statins and nateglinide increased the risk”