Or

Open access

NEWS - Systematic Reviews

Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women – Cochrane Library (free)

“Based on the data available, we can be confident that pelvic floor muscle training can cure or improve symptoms of stress urinary incontinence and all other types of urinary incontinence”

 


Modifying the consistency of food and fluids for swallowing difficulties in dementia – Cochrane Library (free for a limited period)

Summary: Modifying the consistency of food and fluids for swallowing difficulties in dementia (free)

“We are uncertain about the immediate and long-term effects of modifying the consistency of fluid for swallowing difficulties in dementia”

 


Primary antifungal prophylaxis for cryptococcal disease in HIV‐positive people – Cochrane Library (free for a limited period)

Summary: Preventing cryptococcal disease in HIV-positive people – Cochrane Library (free)

“Antifungal prophylaxis reduced the risk of developing and dying from cryptococcal disease. Therefore, where CrAG screening is not available, antifungal prophylaxis may be used in patients with low CD4 counts at diagnosis and who are at risk of developing cryptococcal disease.”

 


Environmental toxic metal contaminants and risk of cardiovascular disease: systematic review and meta-analysis – The BMJ (free)

Editorial: Environmental metals and cardiovascular disease (free)

Commentary: Experts warn of cardiovascular risk from heavy metal pollution – University of Cambridge (free)

“Since metals are associated with cardiovascular disease even at relatively low levels of exposure, population wide strategies to minimize exposure can further contribute to overall cardiovascular prevention efforts” (from @bmj_latest see Tweet)

 


Antibiotics for prolonged wet cough in children – Cochrane Library (link to abstract and plain language summary – $ for full-text)

Commentary: Antibiotics for pediatric chronic wet cough: Cochrane review – Univadis (free registration required)

 


Colloids versus crystalloids for fluid resuscitation in critically ill people – Cochrane Library (link to abstract – $ for full-text)

Summary: Colloids or crystalloids for fluid replacement in critically people – Cochrane Library (free)

“Using starches, dextrans, albumin or FFP (moderate-certainty evidence), or gelatins (low-certainty evidence), versus crystalloids probably makes little or no difference to mortality. Starches probably slightly increase the need for blood transfusion and RRT (moderate-certainty evidence), and albumin or FFP may make little or no difference to the need for renal replacement therapy (low-certainty evidence)”.

 


Pharmacological Treatment of Arterial Hypertension in Children and Adolescents: A Network Meta-Analysis – Hypertension (free)

Commentary: Pediatric hypertension: ACEi/ARBs look like the best choice – Univadis (free)

“According to the present analysis, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers could represent the best choice as antihypertensive treatment for pediatric hypertension. However, because of the paucity of available data for the other classes of antihypertensive drugs, definitive conclusions are not allowed and further randomized controlled trials are warranted.”

 


Blood pressure targets for the treatment of people with hypertension and cardiovascular disease – Cochrane Library (free)

Summary: Blood pressure targets in people with cardiovascular disease – Cochrane Library (free)

“Insufficient evidence to justify lower than standard blood pressure targets in ppl w hypertension + CVD” (via @CochraneHTN see Tweet)

 


To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (link to abstract – $ for full-text)

Summary: To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (free)

“We found low-certainty evidence that either continuation or discontinuation of antiplatelet therapy before non-cardiac surgery may make little or no difference to mortality, bleeding requiring surgical intervention, or ischaemic events”.

 


Nurses as substitutes for doctors in primary care – Cochrane Library (free)

Summary: Nurses as substitutes for doctors in primary care – Cochrane Library (free)

“This updated Cochrane Review indicates that nurses can effectively expand the capacity of the primary care workforce”.

 


Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis – Critical Care Medicine (free for a limited period)

Source: Critical Care Reviews Newsletter

“In adults with septic shock treated with low dose corticosteroids, short- and longer-term mortality are unaffected, adverse events increase, but duration of shock, mechanical ventilation and ICU stay are reduced”.

 


Aldosterone Antagonist Therapy and Mortality in Patients With ST-Segment Elevation Myocardial Infarction Without Heart Failure: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Mineralocorticoid Receptor Antagonists in ST-Segment Elevation Myocardial Infarction – JAMA Internal Medicine (free for a limited period)

Aldosterone antagonists are beneficial for patients with STEMI and reduced ejection fraction. This meta-analysis suggests that patients with STEMI and LVEF greater than 40% or without heart failure also have improved outcomes with aldosterone antagonists.

 


Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents – assessment of adverse events in non-randomised studies – Cochrane Library (link to abstract – $ for full-text)

Summary: Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents – assessment of harmful effects – Cochrane Library (free)

“Our findings suggest that methylphenidate may be associated with a number of serious adverse events as well as a large number of non-serious adverse events in children and adolescents, which often lead to withdrawal of methylphenidate”.

 


Support for midlife anxiety diagnosis as an independent risk factor for dementia: a systematic review – BMJ Open (free)

Commentaries: Moderate to severe mid-life anxiety may be linked to later life dementia – BMJ Open Blog (free) AND Anxiety in middle age linked to dementia later – Reuters (free) AND Expert reaction to a review of the association between mid-life anxiety and later life dementia – Science Media Centre (free)

“The current study isn’t designed to explain how anxiety and dementia might be connected, Iadecola added.

“We cannot say with confidence that anxiety is a cause (risk factor), an early manifestation of the dementia, or only coincidentally associated with it,”” (from Reuters)

 


Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis – Cochrane Library (free for a limited period)

News Release: Featured Review: Uterotonic agents for preventing postpartum haemorrhage – Cochrane Library (free)

Commentary: Review finds more effective drugs to stop bleeding after childbirth – University of Birmingham (free)

“New Cochrane Review suggests ergometrine plus oxytocin; misoprostol plus oxytocin; & carbetocin on its own, are more effective drugs for reducing excessive bleeding at childbirth rather than the current standard use of oxytocin on its own” (via @CochraneUK see Tweet)

 


Antifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)

“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)

 


Safety and efficacy of dual vs. triple antithrombotic therapy in patients with atrial fibrillation following percutaneous coronary intervention: a systematic review and meta-analysis of randomized clinical trials – European Heart Journal (free)

Compared with triple antithrombotic therapy, dual antithrombotic therapy shows a reduction in TIMI major or minor bleeding by 47% with comparable outcomes of major adverse cardiac events.

 


Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease – Cochrane Library (link to abstract – $ for full-text)

Summary: Radial artery versus femoral artery approach for performing coronary catheter procedures in people with coronary artery disease – Cochrane Library (free)

“Transradial approach for diagnostic coronary angiography or PCI (or both) in CAD may reduce short-term net adverse clinical events, cardiac death, all-cause mortality, bleeding, and access site complications”.

 


Non-invasive brain stimulation techniques for chronic pain – Cochrane Library (free)

“There is a lack of high-quality evidence to support or refute the effectiveness of non-invasive brain stimulation techniques for chronic pain”

 


Honey for acute cough in children – Cochrane Library (link to abstract – $ for full-text)

Summary: Honey for acute cough in children – Cochrane Library (free)

“Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan.”

 


Percutaneous vertebroplasty for osteoporotic vertebral compression fracture – Cochrane Library (link to abstract – $ for full-text)

Summary: Featured Review: Vertebroplasty for treating spinal fractures due to osteoporosis – Cochrane Library (free)

High quality evidence shows that vertebroplasty does not provide more clinically important benefits than placebo but may cause people harm”.

 


Safety of early discharge after primary angioplasty in low-risk patients with ST-segment elevation myocardial infarction: A meta-analysis of randomised controlled trials – European Journal of Preventive Cardiology (link to abstract – $ for full-text)

“The findings of this meta-analysis suggested that the early discharge strategy after successful primary angioplasty is safe among selected low-risk STEMI patients. A shorter hospital stay could benefit both the patients and the healthcare systems”.

 


Macrolide antibiotics for bronchiectasis – Cochrane Library (link to abstract – $ for full-text)

Summary: Macrolide antibiotics for bronchiectasis – Cochrane Library (free)

“Long-term macrolide therapy may reduce the frequency of exacerbations and improve quality of life, although supporting evidence is derived mainly from studies of azithromycin, rather than other macrolides, and predominantly among adults rather than children. However, macrolides should be used with caution, as limited data indicate an associated increase in microbial resistance”.

 


Meta-analysis: Long-Term Outcomes of On- Versus Off-Pump Coronary Artery Bypass Grafting – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: Long-Term Outcomes of On- vs. Off-Pump CABG – American College of Cardiology, Latest in Cardiology (free)

“Off pump CABG. probably best used in a limited set of patients…” (via @keaglemd see Tweet)

 


Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data – The Lancet (free)

This meta-analysis of randomized trials showed CABG had a mortality benefit over PCI in patients with multivessel disease, particularly those with diabetes and higher coronary complexity. There was no mortality benefit in patients with left main disease.

 


Surgery for trigger finger – Cochrane Library (link to abstract – $ for full-text)

 


New Cochrane Systematic Reviews – Vaccines for Preventing Influenza and Its Complications

In Healthy Children (free) / Summary (free)

In The Elderly (free) / Summary (free)

In Immunosuppressed Adults With Cancer (free) / Summary (free)

In Healthy Adults (free) / Summary (free)

 


Transcatheter versus surgical aortic valve replacement in patients at low surgical risk: A meta-analysis of randomized trials and propensity score matched observational studies – Catheterization Cardiovascular Interventions (link to abstract – $ for full-text)

Commentary: Meta-Analysis Raises ‘Red Flag’ on TAVR in Low-Risk Patients – TCTMD (free)

“Data from six studies show that while short-term mortality is similar between TAVR and SAVR, more low-risk TAVR patients die by 2 years” (from TCTMD)

 


Page 1 of 512345
Stay Updated in Your Specialty
No spam, just news
Unsubscribe with one click

 

Daily

 

Weekly or Less Often 
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •