Comparative Efficacy of Interventions for Aggressive and Agitated Behaviors in Dementia: A Systematic Review and Network Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia – St. Michael’s Hospital (free) AND To ease dementia agitation, drugs may not be best option – Reuters (free)

Valproate for acute mania – Cochrane Library (free)

Summary: Valproate for acute mania  – Cochrane Library (free)

Related Commentary on Twitter

Valproate for acute mania https://t.co/TkYwwe64Gs Updated review from @Cochrane_CCMD Valproate is an effective antimanic treatment. Valproate may be inferior to olanzapine in adults. Valproate may be inferior to risperidone in acute mania in paediatric and adolescent populations. pic.twitter.com/eHN9dTcIzo

— Cochrane UK (@CochraneUK) October 12, 2019

HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid Analgesics – U.S. Department of Health and Human Services (free)

News Release: HHS Announces Guide for Appropriate Tapering or Discontinuation of Long-Term Opioid Use – U.S. Department of Health and Human Services (free) AND

Commentaries: Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics: The HHS Guide for Clinicians – JAMA (free for a limited period) AND With a new guide to tapering opioids, federal health officials seek a balanced approach to prescribing – STAT (free) AND Don’t Force Patients Off Opioids Abruptly, New Guidelines Say, Warning Of Severe Risks – NPR (free)

Author Interview: The HHS Guide to Patient-Centered Dose Reduction or Discontinuation of Long-term Opioids – JAMA (free)

Related: Pain Management With Opioids in 2019-2020 – JAMA (free registration required)

A brief diet intervention can reduce symptoms of depression in young adults – A randomised controlled trial – PLOS Medicine (free)

Commentaries: Changing Your Diet Can Help Tamp Down Depression, Boost Mood – NPR (free) AND Randomized Controlled Trial in Young Adults Suggests Healthier Diet May Directly Reduce Depression – PLOS (free)

Advice to Young Psychiatrists From a Very Old One – Psychiatric Times (free)

Draft Recommendation Statement: Illicit Drug Use in Children, Adolescents, and Young Adults: Primary Care–Based Interventions – U.S. Preventive Services Task Force (free)

Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment – JAMA Network Open (free)

Commentaries: Alcohol and dementia risk: A complex relationship – Medical News Today (free) AND Alcohol Consumption May Increase Dementia Risk in Older Adults – Psychiatric News Alert (free) AND Expert reaction to study looking at alcohol and risk of dementia and cognitive decline – Science Media Centre (free)

Association of Use of Oral Contraceptives With Depressive Symptoms Among Adolescents and Young Women – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Teens taking oral contraceptives may be at increased risk for depressive symptoms – Brigham and Women’s Hospital (free) AND Teen OC Users More Likely to Report Depressive Symptoms – NEJM (free)

Antidepressant use during pregnancy and the risk of gestational diabetes mellitus: a nested case–control study – BMJ Open (free)

Commentaries: Antidepressants linked to heightened pregnancy related diabetes risk – BMJ (free) AND Antidepressants linked to risk of gestational diabetes – OnMedica (free) AND Antidepressants are linked to a higher gestational diabetes risk in a new study – CNN (free)

Association of Antidepressant Use With Adverse Health Outcomes: A Systematic Umbrella Review – JAMA Psychiatry (free for a limited period)

Editorial: Selective Serotonin Reuptake Inhibitor Use During Pregnancy—Associated With but Not Causative of Autism in Offspring (free for a limited period)

Commentaries: Antidepressant medications appear to be generally safe,study suggests – Linköping University (free) AND Expert reaction to study on association of antidepressant use with adverse health outcomes – Science Media Centre (free)

Long-term outcomes of childhood sexual abuse: an umbrella review – The Lancet Psychiatry (free)

Commentaries: Understanding and responding to the long-term burdens of childhood sexual abuse – The Lancet Psychiatry (free) AND Childhood sexual abuse linked to a range of physical and mental health conditions – University of Oxford (free)

Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents – Pediatrics (free)

News Release: Updated ADHD guideline addresses evaluation, diagnosis, treatment from ages 4-18 – American Academy of Pediatrics (free)

Commentary: Pediatricians Stand By Meds For ADHD, But Some Say Therapy Should Come First – NPR (free)

Incidence and Determinants of Mental Health Service Use After Bariatric Surgery – JAMA Psychiatry (free for a limited period)

Commentaries: Patients more likely to seek psychiatric help after weight-loss surgery – Reuters (free) AND Mental health service use up after bariatric surgery – MedicalXpress (free)

Suicide Prevention Strategies for General Hospital and Psychiatric Inpatients: A Narrative Review – Indian Journal of Psychological Medicine (free)

Related Review: Preventing Suicide Among Inpatients – Canadian Journal of Psychiatry (free)

News Release: First large-scale study of universal screening for autism raises questions about accuracy – Children’s Hospital of Philadelphia (free)

Original Study: Accuracy of Autism Screening in a Large Pediatric Network – Pediatrics (free)

Should antidepressants be used for major depressive disorder? – BMJ Evidence-Based Medicine (free)

Related Meta-analysis: Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis – The Lancet (free)

Related Commentary: Do Antidepressants Work? – The New York Times (10 articles per month are free)

“Generally, all the previous reviews show that antidepressants seem to have statistically significant effects on depressive symptoms, but the size of the effect has questionable importance to most patients.”

Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline – Canadian Medical Association Journal (free)

Commentaries: First-of-its-kind guideline sets out best practices for delivering injectable opioid agonist treatment – The University of British Columbia (free) AND New national guideline sets out best practices for delivering injectable opioid agonist treatment – Canadian Medical Association Journal (free)

School-aged Children Who Are Not Progressing Academically: Considerations for Pediatricians – Pediatrics (free)

News Release: Report guides pediatricians in evaluating children with academic problems – American Academy of Pediatrics (free)

Commentary: Pediatrics Group Offers Guidance for Supporting Children who Struggle in School – NEJM Journal Watch (free)

Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression – JAMA Pediatrics (free)

Commentaries: Youngest children in school year could be at higher risk of mental health problems – London School of Hygiene & Tropical Medicine (free) AND Expert reaction to relative age in school year, and diagnosis of intellectual disability, depression and ADHD – Science Media Centre (free)

Related: Study: Youngest in Class More Likely to be Diagnosed with ADHD (link to abstract and commentaries) AND Systematic Review: Youngest in Class More Likely to be Diagnosed with ADHD (free study and commentaries)

Association Between Screen Media Use and Academic Performance Among Children and Adolescents: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)

Commentaries: Expert reaction to screen media use and academic performance – Science Media Centre (free) AND Not all screen time causes kids to underperform in school, study says – CNN (free)

The clinical effectiveness of sertraline in primary care and the role of depression severity and duration (PANDA): a pragmatic, double-blind, placebo-controlled randomised trial – The Lancet Psychiatry (free)

Commentaries: Examining the antidepressant scattergun approach – The Lancet Psychiatry (free) AND Expert reaction to study on the clinical effectiveness of the antidepressant sertraline – Science Media Centre (free) AND Common antidepressant more effective for anxiety than depression – UPI (free) AND Antidepressants work, but just not how scientists thought they worked – The Conversation (free) AND Antidepressants may reduce anxiety more than depressive symptoms – University College London (free)

Related Commentary on Twitter (Thread – click for more)

Important new trial on the real-world effectiveness of antidepressants (sertraline) in primary care patients. Main finding: There is no evidence that antidepressants effectively treat depression symptoms in real-world patients (effect size: d<0.2) https://t.co/bq9atTwrdo

— Michael P. Hengartner, PhD (@HengartnerMP) September 20, 2019

Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Quick Take: Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation – 2 Minute Medicine (free)

Related: It’s safest to avoid e-cigarettes altogether – unless vaping is helping you quit smoking – The Conversation (free)

Related Commentary on Twitter

Pragmatic RCT (n=1124) finds combining #nicotinepatches with nicotine #ecigarettes -> higher abstinence rates at 6 months (measured using exhaled CO levels) compared with patches + nicotine-free e-cigarettes, or patches alone (7% vs 4% vs 2% respectively)https://t.co/QUfLln1eBv

— ⚖️Health Evidence Matters💡 (@HealthEvMatters) September 12, 2019

Mental health apps are scooping up your most sensitive data. Will you benefit? – STAT (free)

Ritalin at 75: what does the future hold? – The Conversation (free)

Medication-Assisted Treatment for Opioid-Use Disorder – Mayo Clinic Proceedings (free for a limited period)

“It’s All in Your Head”—Medicine’s Silent Epidemic – JAMA Neurology (free for a limited period)

Ketamine and depression: a narrative review – Drug Design, Development and Therapy (free)

Related Systematic Review: Ketamine and other glutamate receptor modulators for depression in adults – Cochrane Library (free)

Associations between paracetamol (acetaminophen) intake between 18 and 32 weeks gestation and neurocognitive outcomes in the child: A longitudinal cohort study – Pediatric and Perinatal Epidemiology (free)

Commentaries: Taking paracetamol during pregnancy may affect the child’s behaviour in early years – The Conversation (free) AND Expert reaction to study looking at paracetamol in pregnancy and behaviour, memory and IQ in children – Science Media Centre (free) AND Paracetamol in pregnancy linked to behaviour problems in children – OnMedica (free)

Related: Meta-Analysis: Prenatal Exposure to Acetaminophen and Risk for ADHD and Autistic Spectrum Disorder (free)

Association Between Antipsychotic Medication Use and Diabetes – Current Diabetes Reports (free)

Depression and Suicidality in Multiple Sclerosis: Red Flags, Management Strategies, and Ethical Considerations – Current Neurology and Neuroscience Reports (free)

Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth – JAMA Psychiatry (link to abstract – $ for full-text)

Author Interview: Associations Between Social Media Time and Internalizing and Externalizing Problems Among US Youth (free audio)

Commentaries: Social Media Use by Adolescents Linked to Internalizing Behaviors – Johns Hopkins Bloomberg School of Public Health (free) AND More Social Media Use Linked to More Depression and Anxiety in Teens – NEJM Journal Watch (free) AND Expert reaction to study looking at social media and adolescent mental health – Science Media Centre (free)

Related: Association of Screen Time and Depression in Adolescence (links to abstract and commentaries) AND The Adverse Effects of Social Media use on Young People’s Mental Health May be Caused by Exposure to Cyberbullying, Loss of Sleep, and Reduced Physical Activity (links to abstract and commentaries) AND Research: This Is Your Brain Off Facebook (free) AND Cohort Study: Social Media Use and Adolescent Mental Health (free) AND Supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn (free articles)

How many premature deaths from pesticide suicide have occurred since the agricultural Green Revolution? – Clinical Toxicology (free)

Commentaries: Scale of suicides by pesticide poisoning revealed – University of Edinburgh (free) AND 15 million people worldwide may have died by suicide with pesticides – UPI (free)

Related: Suicide in the World: WHO Global Health Estimates (free report and commentaries) AND Preventing Suicide: A resource for pesticide registrars and regulators – World Health Organization (free PDF)

The Effectiveness of Selective Serotonin Reuptake Inhibitors for Treatment of Obsessive-Compulsive Disorder in Adolescents and Children: A Systematic Review and Meta-Analysis – Frontiers in Psychiatry (free)

Suicide in the World: Global Health Estimates – World Health Organization (free PDF)

News Release: Suicide: one person dies every 40 seconds – World Health Organization (free)

Commentaries: One person dies by suicide every 40 seconds: new UN health agency report – UN News (free) Suicide kills one person every 40 seconds, says WHO – Reuters (free) AND One person dies every 40 seconds from suicide, WHO says – CNN (free)

The Serotonin Syndrome: From Molecular Mechanisms to Clinical Practice – International Journal of Molecular Sciences (free)

Related Reviews: Serotonin syndrome: Preventing, recognizing, and treating it – Cleveland Clinic Journal of Medicine (free) AND Demystifying serotonin syndrome (or serotonin toxicity) – Canadian Family Physician (free)

The 3 Causes Of Physician Burnout (And Why There’s No Simple Solution) – Forbes (free)

Related: Physician Burnout: A Global Crisis (several resources on the subject)

Medical education needs to stop burning out students — now – STAT (free)

Related: Meta-analysis: The Global Prevalence of Anxiety Among Medical Students (free studies)

Clinical guidelines for the management of treatment-resistant depression: French recommendations from experts, the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental – BMC Psychiatry (free)

Related Guidelines: Clinical guidelines for the management of depression with specific comorbid psychiatric conditions French recommendations from experts (the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental) – BMC Psychiatry (free) AND Depression in adults: recognition and management – National Institute for Health and Care Excellence (free)

Association of Cesarean Delivery With Risk of Neurodevelopmental and Psychiatric Disorders in the Offspring: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: There’s no evidence caesarean sections cause autism or ADHD – The Conversation (free) AND Expert reaction to study on caesareans and neurodevelopmental disorders – Science Media Centre (free)

Diagnosis and treatment of acute alcohol intoxication and alcohol withdrawal syndrome: position paper of the Italian Society on Alcohol – Internal and Emergency Medicine (free PDF)

Assessment and Management of Patients at Risk for Suicide: Synopsis of the 2019 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines – Annals of Internal Medicine (free)

Related Guidelines: Preventing suicide: A community engagement toolkit – World Health Organization (free PDF) AND Preventing suicide in community and custodial settings – National Institute for Health and Care Excellence (free)

Treatments for the Prevention and Management of Suicide: A Systematic Review – Annals of Internal Medicine (free)

Association of Restless Legs Syndrome With Risk of Suicide and Self-harm – JAMA Network Open (free)

Commentaries: Suicide risk nearly three times as high for those with restless legs syndrome – UPI (free) AND Restless Legs Syndrome Linked to Increased Risk for Self-Harm or Suicide – NEJM Journal Watch (free)

A Review on Strategies to Manage Physician Burnout – Cureus (free)

Related: Physician Burnout: A Global Crisis (several resources on the subject)

Source: Hospital Medicine Virtual Journal Club

Bipolar depression: the clinical characteristics and unmet needs of a complex disorder – Current Medical Research and Opinion (free)

Related: Bipolar disorder: assessment and management – National Institute for Health and Care Excellence (free) AND Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder – Bipolar Disorders (free) AND Systematic Review: Treatment for Bipolar Disorder in Adults – Agency for Healthcare Research and Quality (free)

Effect of Continuing Olanzapine vs Placebo on Relapse Among Patients With Psychotic Depression in Remission: The STOP-PD II Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Maintenance Treatment for Psychotic Depressive Disorders: Progress and Remaining Challenges (free for a limited period)

The Global Prevalence of Anxiety Among Medical Students: A Meta-Analysis – International Journal of Environmental Research and Public Health (free)

Related: Medical student wellbeing – a consensus statement from Australia and New Zealand – BMC Medical Education (free) AND Prevalence of Depression, Depressive Symptoms, and Suicidal Ideation Among Medical Students: A Systematic Review and Meta-Analysis – JAMA (free)

Association Between Electronic Cigarette Use and Marijuana Use Among Adolescents and Young Adults: A Systematic Review and Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: Youth Who Use E-Cigarettes May Be More Likely to Use Marijuana, Study Finds – Psychiatric News Alert (free) AND Teens who vape three times more likely to use marijuana – UPI (free) AND Vaping linked to marijuana use in young people, research says – CNN (free)

Draft Recommendation Statement: Screening for Illicit Drug Use, Including Nonmedical Use of Prescription Drugs: Screening – U.S. Preventive Services Task Force (free)

Commentaries: For the first time, U.S. panel recommends screening adults for illicit drug use – STAT (free) AND Screen All Adult Patients for Drug Abuse, National Panel Urges – The New York Times (10 articles per month are free) AND

Roles of cyberbullying, sleep, and physical activity in mediating the effects of social media use on mental health and wellbeing among young people in England: a secondary analysis of longitudinal data – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

Commentaries: Social media use may harm teens’ mental health by disrupting positive activities, study says – CNN (free) AND Social-media use ‘disrupting teen sleep and exercise’ – BBC (free) Expert reaction to study on social media use and the role of cyberbullying, sleep and physical activity in the wellbeing in young people – Science Media Centre (free) AND Social Media’s Ill Effects in Teen Girls: 3 Factors Play Large Role – NEJM Journal Watch (free)

Related Commentary on Twitter

New study suggests that #SocialMedia itself doesn't cause harm to #adolescents, but #MentalHealth harms related to very frequent use in girls might be due to exposure to #cyberbullying, loss of sleep, or reduced physical activity. https://t.co/CGt63GnW7J @russellviner pic.twitter.com/J7SuMORjLj

— The Lancet Child & Adolescent Health (@LancetChildAdol) August 13, 2019

Public Health Policies and Alcohol-related Liver Disease – JHEP Reports (free)

Related: Treating alcohol-related liver disease from a public health perspective – Journal of Hepatology (free) AND WHO Global Status Report on Alcohol and Health 2018 (free report and commentaries) AND Alcohol Use and Burden for 195 Countries and Territories – The Lancet (free study and commentaries)

The Role of Exercise in Preventing and Treating Depression – Current Sports Medicine Reports (free)

News Release: ‘Exercise as Medicine’ for Depression – A Key But Often Overlooked Role In Prevention And Treatment – Wolters Kluwer Health (free)

Related Meta-Analysis: Physical Activity and Incident Depression (free study and commentaries) AND Resistance Exercise for Depressive Symptoms (free study and commentaries) AND Aerobic Exercise for Adult Patients with Major Depressive Disorder (free study and commentaries)

Alcohol Use in Pregnancy and Miscarriage: A Systematic Review and Meta‐Analysis – Alcoholism: Clinical and Experimental Research (free PDF)

Commentary: Alcohol exposure during pregnancy linked with dose-dependent increase in miscarriage risk – News Medical (free)

Evaluation of spin in abstracts of papers in psychiatry and psychology journals – BMJ Evidence-Based Medicine (free)

Commentaries: Expert reaction to study reporting ‘spin’ in abstracts of psychiatry and psychology journals – Science Media Centre (free) AND ‘Spin’ found in over half of clinical trial abstracts published in top psychiatry journals – The British Medical Journal (free)

Related: Systematic Review: Spin in Published Cardiovascular Randomized Trials with Statistically Nonsignificant Primary Outcomes (free study and editorial) AND ‘Spin’ in published biomedical literature: A methodological systematic review – PLOS Biology (free)

If You Smoke Pot, Your Anesthesiologist Needs To Know – Kaiser Health News (free)

Related: Perioperative care of cannabis users: A comprehensive review of pharmacological and anesthetic considerations – Journal of Clinical Anesthesia (free)

“One small study of Colorado patients published in May found marijuana users required more than triple the amount of one common sedation medicine, propofol, as did nonusers.”

The addition of fluoxetine to cognitive behavioural therapy for youth depression (YoDA-C): a randomised, double-blind, placebo-controlled, multicentre clinical trial – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentaries: Psychotherapy should be first-line treatment for depression in young people, trial finds – by Orygen, the National Centre of Excellence in Youth Mental Health (free) AND Psychotherapy should be first option to treat depression in young people, study says – UPI (free)

Generalised anxiety disorder and panic disorder in adults: management – National Institute for Health and Care Excellence (free)

Related Guideline: Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of panic disorder, social anxiety disorder and generalised anxiety disorder (free)

Pharmacologic Management of Agitation in Patients with Dementia – Current Geriatrics Reports (free)

Related: Nonpharmacological Interventions to Reduce Behavioral and Psychological Symptoms of Dementia: A Systematic Review – BioMed Research International (free) AND Systematic review of systematic reviews of non-pharmacological interventions to treat behavioural disturbances in older patients with dementia. The SENATOR-OnTop series – BMJ Open (free)

Mounting Evidence and Netflix’s Decision to Pull a Controversial Suicide Scene – JAMA (free for a limited period)

Related: Release of “13 Reasons Why” Associated with Increase in Youth Suicide Rates (link to abstract and commentaries)

Clinical use of lithium salts: guide for users and prescribers – International Journal of Bipolar Disorders (free)

Prevalence of obstructive sleep apnea in suicidal patients with major depressive disorder – Journal of Psychiatric Research (link to abstract – $ for full-text)

Commentary: Obstructive sleep apnea may be one reason depression treatment doesn’t work – Medical College of Georgia at Augusta University (free)

Association of Genetic and Environmental Factors With Autism in a 5-Country Cohort – JAMA Psychiatry (free for a limited period)

Editorial: The Architecture of Autism Spectrum Disorder Risk: What Do We Know, and Where Do We Go From Here? (free)

Commentaries: Genetic factors are primary cause of autism, study finds – UPI (free) AND Study provides ‘strongest evidence’ yet for autism being a genetic condition – News Medical (free) AND A new study reinforces the conclusion that autism is primarily genetic – Science Based Medicine (free)

Efficacy of Short-term Treatment of Internet and Computer Game Addiction: A Randomized Clinical Trial – JAMA Psychiatry (link to abstract – $ for full-text)

Author Interview: Efficacy of Short-term Treatment of Internet and Computer Game Addiction (free audio)

Commentaries: CBT Program Reduces Addictive Internet Behaviors in Men, Study Finds – Psychiatric News Alert (free) AND Does Short-term Treatment of Internet and Computer Game Addiction Work? – MedicalResearch.com (free) AND Addicted to the internet? Behavioral therapy could work, researchers find – CNN (free)

Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentaries: Study Distinguishes Schizophrenia Drug Effects Among Patients – MD Magazine (free) AND New Guidance on Antipsychotic Choice – Medscape (free registration required)

“These findings will aid clinicians in balancing risks versus benefits of those drugs available in their countries. They should consider the importance of each outcome, the patients’ medical problems, and preferences.”

The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness – The Lancet Psychiatry (free registration required)

Executive Summary and Podcast: A blueprint for protecting physical health in people with mental illness (free summary, audio and other resources)

Commentaries: Global commission into health inequities of mental illness gives blueprint for change – NICM Health Research Institute at Western Sydney University (free) AND People with mental illness experience poorer physical health, and the gap may be getting worse, experts say – ABC News (free) AND Why people with mental illness may face poorer physical health and early death – CNN (free)

Related WHO Guideline: Management of Physical Health Conditions in Adults with Severe Mental Disorders (free)

Related Commentary on Twitter (Thread – Click for More)

Our new @TheLancetPsych Commission #BlueprintMPH tackles the growing health inequalities associated with mental illness – presenting a 'blueprint for protecting physical Health in people with mental illness" https://t.co/l6P3owTnq9 across 5 different Parts, as follows (thread): pic.twitter.com/lCiKvQbzQK

— Joseph Firth (@joefirth7) July 16, 2019

Lithium as the drug of choice for maintenance treatment in bipolar disorder – Acta Psychiatrica Scandinavica (free) (via @J_F_Hayes)

Original Article: A systematic review and meta‐analysis of clinical predictors of lithium response in bipolar disorder – Acta Psychiatrica Scandinavica (free)

Korean Alcohol Guidelines for Moderate Drinking Based on Facial Flushing – Korean Journal of Family Medicine (free PDF)

“individuals with flushing reaction should maintain an alcohol consumption level half of that for non-flushers.”

Post‐intensive care syndrome: its pathophysiology, prevention, and future directions – Acute Medicine & Surgery (free) (via @NydahlPeter)

Related Reviews: Post-intensive care outpatient clinic: is it feasible and effective? A literature review – Revista Brasileira de Medicina Intensiva (free) AND Post-intensive Care Syndrome: an Overview – Journal of Translational Internal Medicine (free) AND Optimizing Post-Intensive Care Unit Rehabilitation – Turkish Thoracic Journal (free)

Association of Screen Time and Depression in Adolescence – JAMA Pediatrics (free for a limited period)

Commentaries: Expert reaction to a study on screen time and depression in adolescents – Science Media Centre (free) AND Increasing social media use tied to rise in teens’ depressive symptoms, study says – CNN (free)

Editorial: Physician burnout: a global crisis – The Lancet (free)

Related Perspectives: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free) AND Panic, chronic anxiety and burnout: doctors at breaking point – The Guardian (free) AND The Burnout Crisis in American Medicine – The Atlantic (free) AND To Combat Physician Burnout and Improve Care, Fix the Electronic Health Record – Harvard Business Review (free commentaries) AND Physician burnout costs up to $17B a year, task force says – HealthcareDive (free)

Related Articles: Systematic Review: Prevalence of Burnout Among Physicians (free) AND Burnout syndrome among medical residents: A systematic review and meta-analysis – PLOS One (free) AND Prevalence of Burnout in Medical and Surgical Residents: A Meta-Analysis – International Journal of Environmental Research and Public Health (free) AND Physician Burnout Can Lead to Major Medical Errors (link to abstract and commentaries) AND Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction (link to abstract and commentaries)

Neuropsychiatric Sequelae in Adolescents With Acute Synthetic Cannabinoid Toxicity – Pediatrics (link to abstract – $ for full-text)

News Release: Study: Seizures, coma more common with synthetic cannabinoids than cannabis – American Academy of Pediatrics (free)

Commentary: Synthetic Cannabinoids Associated with More Comas and Seizures in Teens – NEJM Journal Watch (free)

Change in moderate alcohol consumption and quality of life: evidence from 2 population-based cohorts – Canadian Medical Association Journal (free)

Commentaries: Drinking less might be tied to higher quality of life – Reuters (free) AND Women’s mental health may improve after quitting alcohol – UPI (free) AND Quitting alcohol may improve mental well-being, health-related quality of life – EurekAlert (free)

Related Commentary on Twitter

Quitting alcohol may improve health-related quality of life for women, especially their mental well-being, according to a study by Dr. Xiaoxin Yao and colleagues published in CMAJ: https://t.co/1MrUw2gVVw@hkumed #HKUMed #WomensHealth pic.twitter.com/8UYhQ3163i

— CMAJ (@CMAJ) July 8, 2019

Advances in Understanding the Pathophysiology of Chronic Fatigue Syndrome – JAMA (free for a limited period)

Exposure to Antidepressant Medication and the Risk of Incident Dementia – The American Journal of Geriatric Psychiatry (link to abstract – $ for full-text)

Commentaries: Antidepressants in old age may increase risk of dementia, Israeli study finds – The Times of Israel (free) AND Antidepressant use in older age is linked to increased dementia risk – Univadis (free registration required)

Suicide amongst anaesthetists – an Association of Anaesthetists survey – Anaesthesia (free)

News Release: Survey highlights need for improved mental health guidance & support for anaesthetists – Association of Anaesthetists (free)

Related Commentary on Twitter

🔐This new @AAGBI survey highlights the experiences of ~1,400 anaesthetists who have lost a colleague through suicide.

Most respondents were unaware of their Trust’s policies on mental illness, addiction or suicide.@AAGBI_President @AAGBI_GAT

🔗https://t.co/7UzxNCOw5M pic.twitter.com/O2d0vFQqHH

— Anaesthesia (@Anaes_Journal) July 3, 2019

Alcohol’s Secondhand Harms in the United States: New Data on Prevalence and Risk Factors – Journal of Studies on Alcohol and Drugs (free)

Commentaries: The secondhand harms of drinking impact 1 in 5 adults, study says – CNN (free) AND Alcohol’s secondhand harms prevalent among U.S. women and men – Reuters (free)

Effects of continuous positive airway pressure on depression and anxiety symptoms in patients with obstructive sleep apnoea: results from the sleep apnoea cardiovascular Endpoint randomised trial and meta-analysis – EClinicalMedicine (free)

Commentaries: Mood After CPAP: Fewer Patients With Depression, but not Fewer With Anxiety – EClinicalMedicine (free) AND CPAP provides relief from depression – Flinders University (free)

Related Studies: CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea – New England Journal of Medicine (free) AND Association of Positive Airway Pressure With Cardiovascular Events and Death in Adults With Sleep Apnea: A Systematic Review and Meta-analysis – JAMA (free)

Diagnosing and managing work‐related mental health conditions in general practice: new Australian clinical practice guidelines – The Medical Journal of Australia (free)

Newer-Generation Antidepressants and Suicide Risk in Randomized Controlled Trials: A Re-Analysis of the FDA Database – Psychotherapy and Psychosomatics (free)

Commentary: New study: antidepressants significantly raise the risk of suicide in the treatment of depression for adults (free)

Depression in children and young people: identification and management – National Institute for Health and Care Excellence (free)

Related: AAP Guidelines for Adolescent Depression in Primary Care (free)

Alcohol Use by Youth – Pediatrics (free)

Technical Report: Alcohol Use by Youth – Pediatrics (free)

News Release: American Academy of Pediatrics Emphasizes Dangers of Alcohol to Children, Teens and Young Adults – American Academy of Pediatrics (free)

Higher doses of antidepressants “not optimal”, according to new review – The Mental Elf (free)

Original Article: Meta-analysis: Optimal Dose of Antidepressants in Major Depression (free study and commentaries)

Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort study in Sweden – The BMJ (free)

Editorial: Gabapentinoids linked to new risks, including suicidal behavior (free)

Commentaries: Epilepsy drugs linked to increased risk of suicidal behavior, particularly in young people – The BMJ (free) AND Expert reaction to study on gabapentinoids and risk of suicidal behavior – Science Media Centre (free)

Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis – The Lancet Psychiatry (free)

Commentaries: Which antidepressant doses are optimal? – The Lancet Psychiatry (free) AND Expert reaction to systematic review and dose-response meta-analysis of antidepressants – Science Media Centre (free)

Managing opioid use disorder in primary care: PEER simplified guideline – Canadian Family Physician (free)

Related: Opioid use disorder in primary care: PEER umbrella systematic review of systematic reviews – Canadian Family Physician (free)

Lithium for acute mania – Cochrane Library (free)

Summary: Lithium for the treatment of acute mania – Cochrane Library (free)

Effect of Exposure to Gun Violence in Video Games on Children’s Dangerous Behavior With Real Guns: A Randomized Clinical Trial – JAMA Network Open (free)

Commentaries: Gun Violence in Video Games and Subsequent Firearm Play: An Argument for the Safe Storage of Firearms – JAMA Network Open (free) AND Kids who play violent videogames may be more likely to pick up a gun and pull the trigger – Reuters (free) AND Expert reaction to study on violent video games and behaviour with real guns – Science Media Centre (free)

Antidepressants and weight gain: long-term population impact #SUSANAsurvey – The Mental Elf (free)

Original Study: Cohort Study: Weight Gain with Antidepressant Utilization (free study and commentaries)

The Serotonin Syndrome: From Molecular Mechanisms to Clinical Practice – International Journal of Molecular Sciences (free)

WHO Redefines Burnout As A ‘Syndrome’ Linked To Chronic Stress At Work – NPR (free)

See also: Burn-out an “occupational phenomenon”: International Classification of Diseases – World Health Organization (free)

Related Commentary on Twitter

#Burnout is included in the 11th Revision of the International Classification of Diseases (#ICD11) as an occupational phenomenon.
It is NOT classified as a medical condition https://t.co/t9pjcv3ctX pic.twitter.com/FF6Zzfwoj7

— World Health Organization (WHO) (@WHO) May 28, 2019

Estimating the Attributable Cost of Physician Burnout in the United States – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Physician burnout costs the US health care system approximately $4.6 billion a year – American College of Physicians (free) AND Doctors are burning out twice as fast as other workers. The problem’s costing the US $4.6 billion each year. – Business Insider (free) AND Physician Burnout Costs the U.S. Billions of Dollars Each Year – TIME (free)

Related: Physician Burnout Costs up to $17B a Year, Task Force Says (articles and commentaries on the subject)

Related Commentary on Twitter

The economics of doctor burnout: ~$5B/year, and that isn't even factoring in the cost of the doubling of medical errors https://t.co/fqn0LenWzl @AnnalsofIM pic.twitter.com/ZLNOhvYB1h

— Eric Topol (@EricTopol) May 27, 2019

Evolving Issues in the Treatment of Depression – JAMA (free for a limited period)

Author Interview: New Approaches to Management of Depression (free audio)

European guidelines for personality disorders: past, present and future – Borderline Personality Disorder and Emotion Dysregulation (free)

Antidepressant withdrawal: slower and lower tapering of SSRIs – The Mental Elf (free)

Related: Antidepressant Withdrawal Syndrome – Therapeutics Initiative (free) AND Many People Taking Antidepressants Discover They Cannot Quit – The New York Times (10 articles per month are free)

Trends in Suicide Among Youth Aged 10 to 19 Years in the United States, 1975 to 2016 – JAMA Network Open (free)

Commentaries: Increasing Suicide Rates in Early Adolescent Girls in the United States and the Equalization of Sex Disparity in Suicide: The Need to Investigate the Role of Social Media – JAMA Network Open (free) AND Suicide Rate For Girls Has Been Rising Faster Than For Boys, Study Finds – NPR (free) AND Suicide rates in girls are rising, study finds, especially in those age 10 to 14 – CNN (free)

A Review of Novel Antidepressants: A Guide for Clinicians – Cureus (free)

Mental health in elite athletes: International Olympic Committee consensus statement (2019) – British Journal of Sports Medicine (free)

How Much Alcohol Can You Drink Safely? – The New York Times Magazine (10 articles per month are free)

Related Articles: Alcohol Use and Burden for 195 Countries and Territories (free) AND Meta-analysis: Risk Thresholds for Alcohol Consumption (free )

Alcohol-related harm to others in England: a cross-sectional analysis of national survey data – BMJ Open (free)

Commentaries: One in five people in England harmed by others’ drinking over past year – Blog BMJ Open (free) AND One in five people harmed by other people’s drinking – OnMedica (free) AND One in five harmed by others drinking alcohol over past year, survey finds – The Guardian (free) AND Expert reaction to study quantifying the harm of other people’s drinking – Science Media Centre (free)

Internet-delivered cognitive behaviour therapy for chronic health conditions: a systematic review and meta-analysis – Journal of Behavioral Medicine (free)

Management of perinatal depression with non-drug interventions – The BMJ (free)

International incidence of psychotic disorders, 2002–17: a systematic review and meta-analysis – The Lancet Public Health (free)

Commentary: Towards a public health approach to psychotic disorders – The Lancet Public Health (free)

FDA requires stronger warnings about rare but serious incidents related to certain prescription insomnia medicines – U.S. Food & Drug Administration (Free)

For Consumers: Taking Z-drugs for Insomnia? Know the Risks – U.S. Food & Drug Administration (free)

Commentaries: Drug Agency Calls for Strong Warning Labels on Popular Sleep Aids – The New York Times (10 articles per month are free) AND FDA Requires Stronger Warnings for Common Insomnia Medications – Psychiatric News Alert (free)

Release of “13 Reasons Why” associated with increase in youth suicide rates – NIH News Releases (free)

Original Study: Association Between the Release of Netflix’s 13 Reasons Why and Suicide Rates in the United States: An Interrupted Times Series Analysis – Journal of the American Academy of Child and Adolescent Psychiatry (link to abstract – $ for full-text)

Related Study: Internet Searches for Suicide Following the Release of “13 Reasons Why” (free study and commentaries)

“NIH-supported study highlights the importance of responsible portrayal of suicide by the media.”

Self-management interventions for people with severe mental illness: systematic review and meta-analysis – The British Journal of Psychiatry (free)

The Effects of Dietary Improvement on Symptoms of Depression and Anxiety: A Meta-Analysis of Randomized Controlled Trials – Psychosomatic Medicine (free)

Commentaries: Healthy diet can ease symptoms of depression – University of Manchester (free) AND Many Different Diets Can Improve Mood And Reduce Depression Symptoms, Study Finds – Forbes (free)

Effectiveness and Acceptability of Cognitive Behavior Therapy Delivery Formats in Adults With Depression: A Network Meta-analysis – JAMA Psychiatry (free for a limited period)

Editorial: Can Network Meta-analysis Substitute for Direct Comparisons in Psychotherapy Trials? (free for a limited period)

Commentaries: Certain Variations of CBT Found as Effective as Individual CBT – Psychiatric News Alert (free) AND Group, telephone, guided CBT treatment effective for depression – MedicalXpress (free)

ACMT Position Statement: Addressing Pediatric Cannabis Exposure – Journal of Medical Toxicology (free)

Towards artificial intelligence in mental health by improving schizophrenia prediction with multiple brain parcellation ensemble-learning – NPJ Schizophrenia (free)

Commentary: Improved AI-based tool increases accuracy of schizophrenia diagnosis – University of Alberta (free)

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation – Cochrane Library (free)

Commentaries: Nicotine replacement: when quitting cigarettes, consider using more nicotine, not less – The Conversation (free) AND Nicotine replacement therapy: new evidence on help to quit smoking – Evidently Cochrane (free) AND Nicotine replacement therapy more successful in combination form – Nuffield Department of Primary Care Health Sciences (free)

Related Commentary on Twitter

Featured Cochrane Review: Different doses, durations and modes of delivery of #nicotine replacement therapy for #smoking cessation from @CochraneTAG – Read comments from lead author https://t.co/WBvMA74iaK and the full review https://t.co/QFLx9Wb9Xc pic.twitter.com/tk2J6WRT3Z

— Cochrane (@cochranecollab) April 18, 2019

Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis – The BMJ (free)

Commentaries: The accuracy of the Patient Health Questionnaire-9 for detecting major depression – The BMJ Opinion (free) AND Screening tools for depression offer value when combined with an informed shared decision process – The BMJ Opinion (free) AND Using the Patient Health Questionnaire-9 to Screen for Major Depression – NEJM Journal Watch (free)

Smoking cessation for people with severe mental illness (SCIMITAR+): a pragmatic randomised controlled trial – The Lancet Psychiatry (free)

Commentaries: Smoking cessation in people with serious mental illness – The Lancet Psychiatry (free) AND New intervention doubles quit rate among smokers with severe mental illness – University of York (free) AND Smoking cessation for people with severe mental illness? “Oh yes they can!” SCIMITAR+ – The Mental Elf (free)

Stress related disorders and risk of cardiovascular disease: population based, sibling controlled cohort study – The BMJ (free)

Editorial: Stress, psychiatric disorders, and cardiovascular disease (free)

Commentaries: Stress-related disorders linked to heightened risk of cardiovascular disease – The BMJ (free) AND Stress from Traumatic Events Linked to Increased Risk of Heart Disease – MedicalResearch.com (free) AND Expert reaction to study looking at stress related disorders and risk of cardiovascular disease – Science Media Centre (free)

Related Commentary on Twitter

Stress related disorders–conditions triggered by a significant life event or trauma–may be linked to a heightened risk of cardiovascular disease (CVD), finds a large Swedish study published in @bmj_latest today https://t.co/01pyFcInu8 Linked editorial: https://t.co/vt7EWu4g9v pic.twitter.com/F9C77VJ9M2

— BMJ (@bmj_company) April 11, 2019

State of the Art Review: Depression in primary care: part 1—screening and diagnosis – The BMJ (free for a limited period)

Depression in primary care: part 2—management

Related Commentary on Twitter

#BMJInfographic Managing depression—this visual summary provides a guide to options for primary care. Click here to see the interactive version: https://t.co/6LpVKsMYxs @will_s_t pic.twitter.com/dZVsiwkNPF

— The BMJ (@bmj_latest) April 8, 2019

Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China – The Lancet (free)

Commentaries: Unite for a Framework Convention for Alcohol Control – The Lancet (free) AND Even one alcoholic drink a day can raise risk of stroke, study says – CNN (free) AND Expert reaction to research on alcohol intake and stroke – Science Media Centre (free) AND Major study debunks myth that moderate drinking can be healthy – Reuters (free)

Related: Alcohol Use and Burden for 195 Countries and Territories (free study and commentaries) AND WHO Global Status Report on Alcohol and Health 2018 (free study and commentaries)

Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network meta-analysis – The BMJ (free)

Commentary: Consider non-surgical brain stimulation for severe depression, say experts – The BMJ (free)

Systematic Review: Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF)

Clinical guideline for the diagnosis and management of work-related mental health conditions in general practice – National Health and Medical Research Council, Australian Government (NHMRC) (free PDF)

See also: Short Form Guideline (free PDF) AND GP Summary (free PDF)

Commentary: Managing work-related mental health conditions in family medicine  – Canadian Medical Association Journal (free for a limited period)

Related Commentary on Twitter

New guidance aims to support family physicians to help patients whose mental illness arises in the workplace: https://t.co/LomlqKC61J#familymedicine #primarycare #mentalhealth pic.twitter.com/sFN6ji2EHg

— CMAJ (@CMAJ) March 26, 2019

Differences in Parent-Toddler Interactions with Electronic Versus Print Books – Pediatrics (link to abstract – $ for full-text)

Commentaries: Does story time with an e-book change how parents and toddlers interact? – University of Michigan (free) AND Print Books Better Than E-Books for Parent-Toddler Interaction – NEJM Journal Watch (free) AND Reading to Your Toddler? Print Books Are Better Than Digital Ones – The New York Times (10 articles per month are free)

The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study – The Lancet Psychiatry (free)

Commentaries: Cannabis and psychosis: triangulating the evidence – The Lancet Psychiatry (free) AND Expert reaction to daily cannabis use, potency and psychosis – Science Media Centre (free) AND Daily or high-potency cannabis increases risk of psychotic disorder, study finds – CNN (free) AND Daily cannabis and skunk users run higher psychosis risk – Reuters (free)

Psychosis with Methylphenidate or Amphetamine in Patients with ADHD – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Some ADHD medicines may increase psychosis more than others, ‘real-world’ data show – STAT (free) AND With ADHD, amphetamine has double the psychosis risk of methylphenidate – Reuters (free) AND Big data study identifies drugs that increase risk of psychosis in youth with ADHD – McLean Hospital (free)

Best Practices for Evaluation and Treatment of Agitated Children and Adolescents (BETA) in the Emergency Department: Consensus Statement of the American Association for Emergency Psychiatry – West Journal of Emergency Medicine (free)

Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005–2017 – Journal of Abnormal Psychology (free PDF)

Commentaries: A Rise In Depression Among Teens And Young Adults Could Be Linked To Social Media Use – NPR (free) AND Mental health issues increased significantly in young adults over last decade – American Psychological Association (free)

Brazilian guidelines for the management of psychomotor agitation – Brazilian Journal of Psychiatry (free articles)

Part 1. Non-pharmacological approach

Part 2. Pharmacological approach

Guidelines for the Evaluation and Treatment of Perimenopausal Depression: Summary and Recommendations – Journal of Women’s Health (free)

Clinical Guidance on the Identification and Management of Treatment-Resistant Schizophrenia – The Journal of Clinical Psychiatry (free)

FDA approves new nasal spray medication for treatment-resistant depression; available only at a certified doctor’s office or clinic – U.S. Food & Drug Administration (free)

Commentaries: A ketamine-like drug is the first new antidepressant to get FDA approval in years: But it’s also controversial. – Vox (free) AND FDA Approves Intranasal Esketamine as Adjunctive Treatment for Depression – NEJM Journal Watch (free)

“But while some patient and doctor groups are hailing the approval, others aren’t so sure there’s enough evidence to justify it. That’s because the benefits of ketamine and esketamine aren’t yet well-understood. According to the FDA, the drug has only been studied in four clinical trials, three of them lasting just four weeks. And the results were pretty mixed.” (from Vox)

Related Commentary on Twitter

#FDA never learns from its past mistakes.
20 yrs ago, approved #Oxycontin, supposedly w restrictions.
We know how well those safety checks worked.
Now same blindness to risks of promoting #esketamine.
Doesnt it know people with #Depression will self medicate with street Special K https://t.co/FEj8S4QIFw

— Allen Frances (@AllenFrancesMD) March 6, 2019

Treatment of Anorexia Nervosa—New Evidence-Based Guidelines – Journal of Clinical Medicine (free)

Long work hours, weekend working and depressive symptoms in men and women: findings from a UK population-based study – Journal of Epidemiology & Community Health (free)

Commentaries: Working long hours linked to depression in women – University College London (free) AND Long Works Hours May Hike Depression Risk in Women – PsychCentral (free) AND Are women who work long hours more likely to be depressed? – NHS (free)

Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Patients Not Fully Responsive to Antidepressants, CBT Alone Found to Improve With Combined Therapies – Psychiatric News Alert (free) AND What to Do When Depression Doesn’t Remit with Monotherapy – NEJM Journal Watch (free for a limited period)

Best Practices for Evaluation and Treatment of Agitated Children and Adolescents (BETA) in the Emergency Department: Consensus Statement of the American Association for Emergency Psychiatry – West Journal of Emergency Medicine (free PDF)

Related Guideline: Evaluation and Management of Children and Adolescents With Acute Mental Health or Behavioral Problems. Part I: Common Clinical Challenges of Patients With Mental Health and/or Behavioral Emergencies – Pediatrics (free)

Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)

Predictive Validity of a 2-Question Alcohol Screen at 1-, 2-, and 3-Year Follow-up – Pediatrics (free)

Commentaries: Alcohol Use Disorder: A Pediatric-Onset Condition Needing Early Detection and Intervention – Pediatrics (free) AND 2-Question Screen Identifies Adolescents at Risk for Future Alcohol Use Disorders – 2 Minute Medicine (free)

#140 Psychopharmacology 2.0, Antidepressant Master Class – The Curbsiders Internal Medicine Podcast (free)

Deprescribing benzodiazepine receptor agonists taken for insomnia: a review and key messages from practice guidelines – Polish Archives of Internal Medicine (free PDF)

Related: Guideline: Deprescribing Benzodiazepines (free guideline and resources) AND Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)

Interesting in learning more about deprescribing benzodiazepines and Z-drugs? Check out our review just published at: https://t.co/aOB40uwFGM. A collaborative effort by members of @GERAScentre @MacDeptMed @HEI_mcmaster @ResearchStJoes @bruyerecare pic.twitter.com/BrwmhM1y1p

— Justin Lee (@JustinLeeMD) February 14, 2019

Association of Behavior in Boys From Low Socioeconomic Neighborhoods With Employment Earnings in Adulthood – JAMA Pediatrics (free for a limited period)

Commentaries: Inattention in Low-Income Boys Tied to Lesser Earnings in Adulthood – PsychCentral (free) AND Low-income boys’ inattention in kindergarten associated with lower earnings 30 years later – Carnegie Mellon University (free) AND Behavior at Age 6 May Predict Adult Income – The New York Times (10 articles per month are free)

Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)

Commentary: Expert reaction to cannabis use in adolescents and risk of depression, anxiety and suicidality – Science Media Centre (free) AND Increased depression and suicidal behavior risk for young cannabis users – McGill University Health Centre (free) AND Cannabis smoking in teenage years linked to adulthood depression – The Guardian (free) AND Teen cannabis use linked to higher risk of adolescent depression – Reuters (free)

Interventions to Prevent Perinatal Depression: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: Implementing the USPSTF Recommendations on Prevention of Perinatal Depression—Opportunities and Challenges (free) AND Perinatal Depression: Recommendations for Prevention and the Challenges of Implementation (free) AND Attention to Prevention—Can We Stop Perinatal Depression Before it Starts? (free)

Author Interview: USPSTF Recommendation: Interventions to Prevent Perinatal Depression (free audio)

Commentaries: Depression During and After Pregnancy Can Be Prevented, National Panel Says. Here’s How. – The New York Times (10 articles per month are free) AND To Prevent Pregnancy-Related Depression, At-Risk Women Advised To Get Counseling – NPR (free)

“The USPSTF recommends that clinicians provide or refer pregnant and postpartum persons who are at increased risk of perinatal depression to counseling interventions. (B recommendation)”

Association of the Youth-Nominated Support Team Intervention for Suicidal Adolescents With 11- to 14-Year Mortality Outcomes: Secondary Analysis of a Randomized Clinical Trial – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Fewer Deaths Seen Among Young Adults Who Got Extra Adult Support as Suicidal Teens – Michigan Medicine (free) AND Intervention for Suicidal Adolescents May Reduce Long-Term Mortality – Psychiatric News Alert (free)

The effects of dietary improvement on symptoms of depression and anxiety: a meta-analysis of randomized controlled trials – Psychosomatic Medicine (free PDF)

Commentaries: Improved Diet Can Ease Depression Symptoms, Enhance Mood – PsychCentral (free) AND Many Different Diets Can Improve Mood And Reduce Depression Symptoms, Study Finds – Forbes (free) AND A diet rich in fiber and vegetables can relieve depression – Medical News Today (free)

Lettuce be happy: A longitudinal UK study on the relationship between fruit and vegetable consumption and well-being – Social Science & Medicine (free)

Commentary: Hearts and minds: fruit and veg boost well-being – University of Leeds (free) AND Eating more fruit and veg ‘improves mental wellbeing’ – NHS Choices (free)

Hallucinations in Children and Adolescents: An Updated Review and Practical Recommendations for Clinicians – Schizophrenia Bulletin (free)

Managing Antidepressant Discontinuation: A Systematic Review – Annals of Family Medicine (free)

Commentary: Psychotherapy Ups Odds of Tapering Off Antidepressants – Medscape (free registration required)

Global, regional, and national burden of suicide mortality 1990 to 2016: systematic analysis for the Global Burden of Disease Study 2016 – The BMJ (free)

Editorial: Suicide falls by a third globally (free for a limited period)

Commentaries: Global suicide mortality: Using data to inform action and monitor progress – The BMJ Opinion (free) AND Global rates of suicide death have fallen by a third since 1990, study finds – CNN (free)

Patterns in Outpatient Benzodiazepine Prescribing in the United States – JAMA Network Open (free)

Commentary: Steep Climb In Benzodiazepine Prescribing By Primary Care Doctors – NPR (free)

Related: A Quiet Drug Problem Among the Elderly – The New York Times (10 articles per month are free) AND Benzodiazepines: our other prescription drug epidemic – STAT (free)

Effect of aerobic exercise on cognition in younger adults: A randomized clinical trial – Neurology (link to abstract – $ for full-text)

Commentary: Exercise may improve thinking skills in people as young as 20 – American Academy of Neurology (free)

Clinical guidelines for the management of depression with specific comorbid psychiatric conditions French recommendations from experts (the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental) – BMC Psychiatry (free)

Related Guideline: Depression in adults: recognition and management – National Institute for Health and Care Excellence (free)

Depression and coronary heart disease: 2018 ESC position paper of the working group of coronary pathophysiology and microcirculation developed under the auspices of the ESC Committee for Practice Guidelines – European Heart Journal (free)

This Is Your Brain Off Facebook – The New York Times (10 articles per month are free)

Original randomized trial, involving nearly 3000 individuals: The Welfare Effects of Social Media (free PDF)

“Expect the consequences to be fairly immediate: More in-person time with friends and family. Less political knowledge, but also less partisan fever. A small bump in one’s daily moods and life satisfaction. And, for the average Facebook user, an extra hour a day of downtime.”

Prevalence of Cannabis Use Among Medical Students: A Systematic Review and Meta-analysis – Substance Abuse: Research and Treatment (free)

“1 in 3 medical students has used cannabis, whereas 8.8% were current users”

The digital drug: Internet addiction spawns U.S. treatment programs – Reuters (free)

Related: Gaming disorder – World Health Organization (free) AND Gaming addiction classified as mental health disorder by WHO – Reuters (free) AND WHO classifies ‘gaming disorder’ as mental health condition – CNN (free) AND Do You Have ‘Gaming Disorder,’ A Newly Recognized Mental Health Condition? – Forbes (free) AND Endless Gaming May Be a Bad Habit. That Doesn’t Make It a Mental Illness – The New York Times (10 articles per month are free) AND Gaming addiction as a mental disorder: it’s premature to pathologise players – The Conversation (free) AND Is ‘Internet Addiction’ Real? – NPR Health News (free)

Association Between Screen Time and Children’s Performance on a Developmental Screening Test – JAMA Pediatrics (free for a limited period)

Commentaries: Expert reaction to study on use of screen time and child development – Science Media Centre (free) AND Too much toddler screen time tied to worse social, motor skills by kindergarten – Reuters (free) AND More screen time for toddlers is tied to poorer development a few years later, study says – CNN (free) AND Screen time ‘may harm toddlers’ – BBC (free) AND Screen time predicts delays in child development, says new research – The Conversation (free)

Related Guidelines: Media devices in pre-school children: the recommendations of the Italian pediatric society – Italian Journal of Pediatrics (free) AND Media and Young Minds – Recommendations from The American Academy of Pediatrics (free)

See also: Children, Adolescents and Screens: What We Know and What We Need To Learn (Pediatrics Supplement with free articles)

Aerobic exercise for adult patients with major depressive disorder in mental health services: A systematic review and meta‐analysis – Depression & Anxiety (free)

Commentary: Aerobic exercise is an effective treatment for depression – NIHR Signal (free)

Related Study: Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study – JAMA Psychiatry (link to abstract – $ for full-text) AND Commentary: Exercise can reduce risk for depression, research shows – UPI (free)

Association of Hydroxylmethyl Glutaryl Coenzyme A Reductase Inhibitors, L-Type Calcium Channel Antagonists, and Biguanides With Rates of Psychiatric Hospitalization and Self-Harm in Individuals With Serious Mental Illness – JAMA Psychiatry (free)

Commentaries: Can Some Common Drugs Also Benefit Mental Health? – PsychCentral (free) AND 3 common drugs associated with reduced risk of hospitalization and harm in serious mental illness – ACP Internist (free)

Hospital Observation Upon Reversal (HOUR) With Naloxone: A Prospective Clinical Prediction Rule Validation Study – Academic Emergency Medicine (free)

Commentary: Study confirms 1-hour discharge rule for patients given naloxone after opiate overdose – Society for Academic Emergency Medicine (free)

Association of Pharmaceutical Industry Marketing of Opioid Products With Mortality From Opioid-Related Overdoses – JAMA Network Open (free)

Editorial: A Perspective Regarding the Current State of the Opioid Epidemic (free)

Author Interview: Marketing of Opioid Products and Mortality From Opioid-Related Overdoses; Comparison of Wait Times for New Patients Between the Private Sector and VA Medical Centers (free)

Commentaries: Study Links More Marketing Of Opioids To More Overdose Deaths – CommonHealth (free) AND Heavy marketing of opioid drugs linked to overdose deaths – UPI (free) AND Study Links Drug Maker Gifts for Doctors to More Overdose Deaths – The New York Times (10 articles per month are free)

Medscape National Physician Burnout, Depression & Suicide Report 2019 (free registration required)

Commentaries: Burnout Rises Above 50% in Some Specialties, New Survey Shows – Medscape (free registration required) AND No quick fix for physician burnout, depression – Reuters (free) AND More than half of physicians are burned out or depressed – HealthExec (free)

Related Perspectives: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free) AND Panic, chronic anxiety and burnout: doctors at breaking point – The Guardian (free) AND The Burnout Crisis in American Medicine – The Atlantic (free) AND Implementing Optimal Team-Based Care to Reduce Clinician Burnout – National Academy of Medicine (free) AND Physician burnout costs up to $17B a year, task force says – HealthcareDive (free)

Related Articles: Physician Burnout Can Lead to Major Medical Errors (link to abstract and commentaries) AND Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction (link to abstract and commentaries) AND Systematic Review: Prevalence of Burnout Among Physicians (link to abstract and commentaries)

Alcohol use and dementia: a systematic scoping review – Alzheimer’s Research & Therapy (free)

Excess Burden of Mental Illness and Hospitalization in Young-Onset Type 2 Diabetes: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Mental Illness Risk Increased in Young Onset Diabetes – MedicalResearch.com (free) AND Young-onset type 2 diabetes associated with increased risk of hospitalization frequently due to mental illness – 2 Minute Medicine (free) AND Young Onset Diabetes Linked to High Rates of Mental Illness, Hospitalization – AJMC (free)

Benzodiazepines or related drugs and risk of pneumonia: A systematic review and meta‐analysis – International Journal of Geriatric Psychiatry (free)

Commentary: Benzodiazepines May Boost Pneumonia Risk, Especially in Seniors – Medscape (free registration required)

The association between adolescent well-being and digital technology use – Nature Human Behavior (link to abstract – $ for full-text)

Commentaries: Technology use explains at most 0.4 percent of adolescent wellbeing, new study finds – University of Oxford (free) AND Expert reaction to adolescent well-being and digital technology use – Science Media Centre (free) AND Screen Time May Be No Worse For Kids Than Eating Potatoes – Forbes (free)

Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of panic disorder, social anxiety disorder and generalised anxiety disorder – Australian & New Zealand Journal of Psychiatry (free)

Suicide among cancer patients – Nature Communications (free)

Commentary: Suicide risk more than quadruples for people with cancer – Penn State (free)

Related Research: Suicidal death within a year of a cancer diagnosis (free study and commentary) AND Risk of Suicide After Cancer Diagnosis in England (free study and commentary)

The effectiveness of art therapy for anxiety in adults: A systematic review of randomised and non-randomised controlled trials – PLOS One (free)

Suicidal death within a year of a cancer diagnosis: A population‐based study – Cancer (free)

Commentary: Suicide risk increases significantly following a cancer diagnosis – Wiley (free)

Related Research: Risk of Suicide After Cancer Diagnosis in England (free study and commentary)

Social Media Use and Adolescent Mental Health: Findings From the UK Millennium Cohort Study – EClinicalMedicine (free)

Commentaries: Social media is more detrimental to girls’ mental health than for boys’ – News Medical (free) AND Depression in girls linked to higher use of social media – The Guardian (free)

Related Research: Gender differences in the associations between age trends of social media interaction and well-being among 10-15 year olds (free study and commentaries)

Ask Suicide-Screening Questions (ASQ) Toolkit – National Institute of Mental Health (free)

Commentary: New pathways for implementing universal suicide risk screening in healthcare settings – NIH News Releases (free)

AAP Policy Statement: Incorporating Recognition and Management of Perinatal Depression Into Pediatric Practice – Pediatrics (free)

Related Technical Report: Incorporating Recognition and Management of Perinatal Depression Into Pediatric Practice – Pediatrics (free)

Different Types and Acceptability of Psychotherapies for Acute Anxiety Disorders in Children and Adolescents: A Network Meta-analysis – JAMA Psychiatry (free)

Commentaries: Group therapy most effective treatment for anxiety in young people – University of Oxford (free) AND Meta-Analysis Finds Group CBT Optimal Psychotherapy for Children, Adolescents With Anxiety – Psychiatric News Alert (free)

Driving with Dementia or Mild Cognitive Impairment: Consensus Guidelines for Clinicians – Royal College of Psychiatrists (free PDF)

Commentary: When should dementia patients stop driving? A new guidance for clinicians – Newcastle University (free)

Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2011–2016 – Centers for Disease Control and Prevention (free PDF)

Commentary: CDC: Top 10 Drugs Involved in Drug Overdose Deaths – MPR (free)

Post-traumatic stress disorder – National Institute for Health and Care Excellence (free)

Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial – The Lancet (free)

Commentaries: Fluoxetine and recovery after stroke – The Lancet (free) AND Fluoxetine (Prozac) Did Not Reduce Risk of Depression After Stroke, But Did Raise Risk of Fractures – MedicalResearch.com (free) AND Common antidepressant does not aid stroke recovery, study finds – University of Edinburgh (free)

Increased Risk of Metabolic Syndrome in Antidepressants Users: A Mini Review – Frontiers in Psychiatry (free)