Podcast: Update in Sleep Medicine

27 Nov, 2019 | 08:08h | UTC

Intensivist Burnout: Running on Empty?

18 Nov, 2019 | 00:26h | UTC

Schizophrenia—An Overview

31 Oct, 2019 | 08:14h | UTC

Schizophrenia—An Overview – JAMA Psychiatry (free for a limited period)


A comprehensive analysis of mortality-related health metrics associated with mental disorders: a nationwide, register-based cohort study – The Lancet (link to abstract – $ for full-text)

Commentaries: Life expectancy mapped for people with mental disorders – The University of Queensland (free) AND Mentally ill die many years earlier than others – Aarhus University (free)


Related Commentary on Twitter (Thread – Click for More)


Homepage: Drug Use – The Lancet (free articles, commentaries, and podcast – registration required)


Valproate for acute mania – Cochrane Library (free)

Summary: Valproate for acute mania  – Cochrane Library (free)


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Should antidepressants be used for major depressive disorder? – BMJ Evidence-Based Medicine (free)

Related Meta-analysis: Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis – The Lancet (free)

Related Commentary: Do Antidepressants Work? – The New York Times (10 articles per month are free)

“Generally, all the previous reviews show that antidepressants seem to have statistically significant effects on depressive symptoms, but the size of the effect has questionable importance to most patients.”


Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Quick Take: Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation – 2 Minute Medicine (free)

Related: It’s safest to avoid e-cigarettes altogether – unless vaping is helping you quit smoking – The Conversation (free)


Related Commentary on Twitter


Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentaries: Study Distinguishes Schizophrenia Drug Effects Among Patients – MD Magazine (free) AND New Guidance on Antipsychotic Choice – Medscape (free registration required)

“These findings will aid clinicians in balancing risks versus benefits of those drugs available in their countries. They should consider the importance of each outcome, the patients’ medical problems, and preferences.”


The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness – The Lancet Psychiatry (free registration required)

Executive Summary and Podcast: A blueprint for protecting physical health in people with mental illness (free summary, audio and other resources)

Commentaries: Global commission into health inequities of mental illness gives blueprint for change – NICM Health Research Institute at Western Sydney University (free) AND People with mental illness experience poorer physical health, and the gap may be getting worse, experts say – ABC News (free) AND Why people with mental illness may face poorer physical health and early death – CNN (free)

Related WHO Guideline: Management of Physical Health Conditions in Adults with Severe Mental Disorders (free)


Related Commentary on Twitter (Thread – Click for More)


Korean Alcohol Guidelines for Moderate Drinking Based on Facial Flushing – Korean Journal of Family Medicine (free PDF)

“individuals with flushing reaction should maintain an alcohol consumption level half of that for non-flushers.”


Physician Burnout: A Global Crisis

12 Jul, 2019 | 07:57h | UTC

Survey: Suicide Amongst Anesthetists

4 Jul, 2019 | 10:47h | UTC

Suicide amongst anaesthetists – an Association of Anaesthetists survey – Anaesthesia (free)

News Release: Survey highlights need for improved mental health guidance & support for anaesthetists – Association of Anaesthetists (free)


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WHO Redefines Burnout As A ‘Syndrome’ Linked To Chronic Stress At Work – NPR (free)

See also: Burn-out an “occupational phenomenon”: International Classification of Diseases – World Health Organization (free)


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Study: Alcohol-related Harm to Others

13 May, 2019 | 01:08h | UTC

BMJ Review: Depression in Primary Care

9 Apr, 2019 | 02:11h | UTC

State of the Art Review: Depression in primary care: part 1—screening and diagnosis – The BMJ (free for a limited period)

Depression in primary care: part 2—management


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Brazilian guidelines for the management of psychomotor agitation – Brazilian Journal of Psychiatry (free articles)

Part 1. Non-pharmacological approach

Part 2. Pharmacological approach


FDA approves new nasal spray medication for treatment-resistant depression; available only at a certified doctor’s office or clinic – U.S. Food & Drug Administration (free)

Commentaries: A ketamine-like drug is the first new antidepressant to get FDA approval in years: But it’s also controversial. – Vox (free) AND FDA Approves Intranasal Esketamine as Adjunctive Treatment for Depression – NEJM Journal Watch (free)

“But while some patient and doctor groups are hailing the approval, others aren’t so sure there’s enough evidence to justify it. That’s because the benefits of ketamine and esketamine aren’t yet well-understood. According to the FDA, the drug has only been studied in four clinical trials, three of them lasting just four weeks. And the results were pretty mixed.” (from Vox)


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