Pediatrics

Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial – The Lancet (free)

Invited Commentary: Angiotensin-II receptor blockade in Marfan syndrome – The Lancet (free)

 

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Homepage: CPR Guidelines (free summaries and infographics)

– 2019 Highlights – Guidelines Update for CPR & ECC

– 2019 FAQ – Guidelines Update for CPR & ECC

– 2019 Infographic – ACLS Guidelines Update

– 2019 Infographic – PALS Guidelines Update

Original Guidelines: AHA Updates on Advanced Cardiovascular Life Support (ACLS) (free) AND AHA Updates in Pediatric Life Support (free)

 

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Review: Celiac Disease

4 Dec, 2019 | 08:20h | UTC

The case for mandatory vaccination – Nature (free)

Related Opinion: Mandate Vaccination with Care (free commentaries)

“When immunization rates dip, legislation is often strengthened. But does the evidence stack up?”

 


NICE Guideline: Fever in Under 5s

20 Nov, 2019 | 10:49h | UTC

Results of the Fontan Udenafil Exercise Longitudinal (FUEL) Trial – Circulation (free for a limited period)

Commentaries: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial – Children’s Hospital of Philadelphia (free) AND Pediatric drug trial finds benefit in teens with heart defect – NIH News Releases (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

 

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AHA Updates in Pediatric Life Support

18 Nov, 2019 | 00:55h | UTC

Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele – New England Journal of Medicine (link to abstract – $ for full-text)

Editorial: Realizing the Dream of Molecularly Targeted Therapies for Cystic Fibrosis (free)

Related Research: Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Three-drug combo improves lung function in most common genetic form of cystic fibrosis – UT Southwestern Medical Center (free)

 

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Quantifying risks and interventions that have affected the burden of diarrhoea among children younger than 5 years: an analysis of the Global Burden of Disease Study 2017 – The Lancet Infectious Diseases (free)

Invited Commentary: Early childhood diarrhoea: from data to interventions (free)

Related Global Burden of Disease Report: Global Burden of Diarrhea (free)

 

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Mapping 123 million neonatal, infant and child deaths between 2000 and 2017 – Nature (free)

Commentaries: Tackling inequality could save millions of children – Institute for Health Metrics and Evaluation (free) AND Where You’re Born Even Within A Country Still Matters – NPR (free)

 

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Special Issue: Neonatal ECMO in 2019

15 Oct, 2019 | 10:11h | UTC

Global Atlas on Childhood Obesity

7 Oct, 2019 | 06:01h | UTC

Penicillin V four times daily for five days versus three times daily for 10 days in patients with pharyngotonsillitis caused by group A streptococci: randomised controlled, open label, non-inferiority study – The BMJ (free)

 

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Immunogenicity, effectiveness, and safety of measles vaccination in infants younger than 9 months: a systematic review and meta-analysis – The Lancet Infectious Diseases (free)

Related Article: Effect of measles vaccination in infants younger than 9 months on the immune response to subsequent measles vaccine doses: a systematic review and meta-analysis – The Lancet Infectious Diseases (free)

Invited Commentary: Early vaccination: a provisional measure to prevent measles in infants (free)

 

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The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017 – The Lancet Oncology (free)

Commentaries: Global burden of childhood cancer: growing, but controllable – The Lancet Oncology (free) AND Globally, more than 11 million years of healthy life lost due to childhood cancer in 2017 – The Lancet (free)

 

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Updates in Pediatric Hospital Medicine

24 Jul, 2019 | 01:02h | UTC

Clinical Practice: Measles

14 Jul, 2019 | 20:05h | UTC

Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children – Nature Medicine (link to abstract – $ for full-text)

News Release: A third of children up to age 3 exposed to Zika in-utero have neurological problems – UCLA (free) AND Maternal Zika infection tied to poor development in 32% of tots – CIDRAP (free)

 

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Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study – The Lancet (free)

Commentaries: What the PERCH study means for future pneumonia strategies – The Lancet (free) AND Study: Viruses cause most global pediatric pneumonia – CIDRAP (free)

 

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