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Pain Medicine

RCT | US-guided pudendal nerve block vs. US-guided penile nerve block for analgesia during pediatric circumcision.

15 Dec, 2022 | 13:31h | UTC

Randomized controlled trial (RCT) comparing ultrasound-guided pudendal nerve block with ultrasound-guided penile nerve block for analgesia during pediatric circumcision – Regional Anesthesia & Pain Medicine (link to abstract – $ for full-text)

 


RCT | Medication optimization vs. cognitive behavioral therapy in patients with chronic low back pain.

14 Dec, 2022 | 14:58h | UTC

Effect of Medication Optimization vs Cognitive Behavioral Therapy Among US Veterans With Chronic Low Back Pain Receiving Long-term Opioid Therapy: A Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


SR | Use of acupuncture for adult health conditions, 2013 to 2021.

14 Dec, 2022 | 14:54h | UTC

Use of Acupuncture for Adult Health Conditions, 2013 to 2021: A Systematic Review – JAMA Network Open

 


RCT | Ropivacaine perineal infiltration after episiotomy did not reduce postpartum pain.

13 Dec, 2022 | 14:16h | UTC

Ropivacaine perineal infiltration for postpartum pain management in episiotomy repair: a double-blind, randomised, placebo-controlled trial – BJOG (link to abstract – $ for full-text)

 


SR | Global prevalence and incidence of shoulder pain.

13 Dec, 2022 | 14:09h | UTC

A systematic review of the global prevalence and incidence of shoulder pain – BMC Musculoskeletal Disorders

 


ASCO Guideline | Use of opioids for adults with pain from cancer or cancer treatment.

7 Dec, 2022 | 14:32h | UTC

Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline – Journal of Clinical Oncology

 


Phase 2b RCT | Cannabidiol oil failed to relieve symptoms in advanced cancer.

1 Dec, 2022 | 14:04h | UTC

Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD) – Journal of Clinical Oncology

Commentary: Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows – The Guardian

Related:

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults. 

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife. 

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero. 

Cannabis-related allergies: an international overview and consensus recommendations.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

 


M-A | Placebo response and media attention in randomized clinical trials assessing cannabis-based therapies for pain.

1 Dec, 2022 | 14:06h | UTC

Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis – JAMA Network Open

News Release: Positive media coverage of cannabis studies regardless of therapeutic effect – Karolinska Institutet

Commentaries: 

Cannabis is no better than a placebo for treating pain – new research – The Conversation

Media Coverage, Placebo Response Linked to Pain Relief Seen in Cannabinoid Trials – Psychiatric News Alert

 

Commentary on Twitter

 


Review | Pain management strategies in urethral reconstruction.

30 Nov, 2022 | 13:30h | UTC

Pain management strategies in urethral reconstruction: a narrative review – Translational Andrology and Urology

 


Podcast | Opioid use disorder and acute pain in hospitalized patients.

29 Nov, 2022 | 14:05h | UTC

#366 Opioid Use Disorder and Acute Pain in the Hospitalized Patient – The Curbsiders

 


M-A | Acupuncture for low back and/or pelvic pain during pregnancy.

23 Nov, 2022 | 13:52h | UTC

Acupuncture for low back and/or pelvic pain during pregnancy: a systematic review and meta-analysis of randomised controlled trials – BMJ Open

News Release: Acupuncture can relieve lower back/pelvic pain often experienced during pregnancy – BMJ Newsroom

 


RCT | Comparison between different corticosteroid injection techniques in adhesive capsulitis.

21 Nov, 2022 | 14:18h | UTC

Comparison Between Corticosteroid Injection Into Coracohumeral Ligament and Inferior Glenohumeral Capsule and Corticosteroid Injection Into Posterior Glenohumeral Recess in Adhesive Capsulitis: A Prospective Randomized Trial – Pain Physician (PDF) 

 


M-A | Epidemiology of persistent postoperative opioid use after cardiac surgery.

21 Nov, 2022 | 13:36h | UTC

Epidemiology of persistent postoperative opioid use after cardiac surgery: a systematic review and meta-analysis – British Journal of Anaesthesia 

 


Review | Current approaches to acute postoperative pain management after major abdominal surgery.

21 Nov, 2022 | 13:38h | UTC

Current approaches to acute postoperative pain management after major abdominal surgery: a narrative review and future directions – British Journal of Anaesthesia 

 


M-A | Comparative benefits and harms of individual opioids for chronic non-cancer pain.

21 Nov, 2022 | 13:34h | UTC

Comparative benefits and harms of individual opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised trials – British Journal of Anaesthesia 

 

Commentary on Twitter 

https://twitter.com/BJAJournals/status/1552579835217821698 

 


RCT | Genicular nerve block offers short-term pain relief in patients with knee osteoarthritis.

15 Nov, 2022 | 12:50h | UTC

Genicular Nerve Block for Pain Management in Patients With Knee Osteoarthritis: A Randomized Placebo-Controlled Trial – Arthritis & Rheumatology

Commentary: Genicular nerve block may provide short-term pain relief for knee osteoarthritis – medwire News

 


RCT | Comparison of acupuncture vs. sham acupuncture in the treatment of aromatase inhibitor–related joint pain.

15 Nov, 2022 | 12:47h | UTC

Comparison of Acupuncture vs Sham Acupuncture or Waiting List Control in the Treatment of Aromatase Inhibitor–Related Joint Pain: A Randomized Clinical Trial – JAMA Network Open

Commentary: Aromatase inhibitors and acupuncture in breast cancer: Spinning a negative study, four years later – Science-based Medicine

 

Commentary on Twitter

https://twitter.com/JAMANetworkOpen/status/1591113526222913538

 


RCT | Effect of local anesthetic infiltration on postoperative pain after laparoscopic cholecystectomy.

10 Nov, 2022 | 13:56h | UTC

Effect of local anaesthetic infiltration on postoperative pain after laparoscopic cholecystectomy: randomized clinical trial – BJS Open

 

Commentary on Twitter

 


CDC Clinical Practice Guideline for prescribing opioids for pain.

7 Nov, 2022 | 13:00h | UTC

CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 – Morbidity and Mortality Weekly Report

Commentaries:

Prescribing Opioids for Pain — The New CDC Clinical Practice Guideline – New England Journal of Medicine

CDC issues new opioid prescribing guidance, giving doctors more leeway to treat pain – NPR

 


Updated systematic review on cannabis and other plant-based treatments for chronic pain.

7 Nov, 2022 | 12:39h | UTC

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Related:

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults. 

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife. 

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero. 

Cannabis-related allergies: an international overview and consensus recommendations.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

 


M-A | Risk of major adverse events associated with gabapentinoid and opioid combination therapy.

4 Nov, 2022 | 13:13h | UTC

Risk of major adverse events associated with gabapentinoid and opioid combination therapy: A systematic review and meta-analysis – Frontiers in Pharmacology

 


RCT | Electroacupuncture shortened the duration of postoperative ileus after laparoscopic surgery for colorectal cancer.

3 Nov, 2022 | 14:17h | UTC

Electroacupuncture vs Sham Electroacupuncture in the Treatment of Postoperative Ileus After Laparoscopic Surgery for Colorectal Cancer: A Multicenter, Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Invited Commentary: Will Acupuncture Be the Next Addition to Enhanced Recovery After Surgery Protocols? – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

 


NICE Guideline | Osteoarthritis in over 16s: diagnosis and management.

2 Nov, 2022 | 14:29h | UTC

Osteoarthritis in over 16s: diagnosis and management – National Institute for Health and Care Excellence

 


Phase 2/3 RCT | Zavegepant nasal spray for the acute treatment of migraine.

1 Nov, 2022 | 12:01h | UTC

Zavegepant nasal spray for the acute treatment of migraine: A Phase 2/3 double-blind, randomized, placebo-controlled, dose-ranging trial – Headache

 


RCT | Liposomal bupivacaine transversus abdominis plane block did not reduce postoperative pain after abdominal wall reconstruction.

31 Oct, 2022 | 13:30h | UTC

The Efficacy of Liposomal Bupivacaine on Postoperative Pain Following Abdominal Wall Reconstruction: A Randomized, Double-blind, Placebo-controlled Trial – Annals of Surgery (link to abstract – $ for full-text)

 


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