NICE Guideline: Sinusitis (acute): antimicrobial prescribing (free)
News release: Antibiotics should not be used to treat the majority of sinus infections, NICE says (free)
Olfactory Dysfunction Predicts Subsequent Dementia in Older U.S. Adults – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
Commentaries: Elderly Who Have Trouble Identifying Odors Face Risk of Dementia – NewsWise (free) AND Poor Sense of Smell May Signal Impending Dementia – The New York Times (10 articles per month are free) AND Sniffing out dementia with a simple smell test – Medical News Today (free)
Olfaction and incident Parkinson disease in US white and black older adults – Neurology (link to abstract – $ for full-text)
Commentaries: Parkinson’s: Sniff test could predict risk up to a decade earlier – Medical News Today (free) AND Can a Smell Test Predict Parkinson’s? – MedPage Today (free registration required) AND Scratch-and-sniff test could predict Parkinson’s even earlier – Michigan State University, via EurekAlert (free) AND Parkinson’s Disease May Be Diagnosed With Smell Test 10 Years Before Symptoms – Medical Daily (free)
Rapid Recommendations: Corticosteroids for sore throat: a clinical practice guideline – The BMJ (free text and infographic)
See also other Rapid Recommendations from The BMJ (all free)
Commentaries: Dietary Approach Found as Effective as Medications for Treating Type of Reflux Disease – The JAMA Network (free) AND Treating Reflux With Diet – The New York Times (10 articles per month are free)
A small retrospective cohort study suggests a plant-based, Mediterranean-style diet may be as effective as medication.
Author interview audio: Natural History and Tumor Volume Kinetics of Papillary Thyroid Cancers (free)
Commentaries: Findings Support Use of Active Surveillance for Low-Risk Papillary Thyroid Cancer – The JAMA Network (free) AND Many People Can Delay Treatment For Thyroid Cancer, Study Finds – NPR (free)
Effect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Oral Steroid Does Not Reduce Lower Respiratory Tract Infection Symptoms in Nonasthmatic Adults – JAMA Network (free) AND No Benefit for Oral Steroids in Lower Respiratory Tract Infection – Medscape (free registration required) AND Don’t use steroids for chest infections, GPs advised – Pulse (free)
In patients with acute respiratory infection, without evidence of pneumonia or asthma, the addition of corticosteroids did not reduce symptom duration or severity.
Source: ACP Journal Club ($)
Dexamethasone increased complete symptom resolution at 48 hours (35.4% vs 27.1%), but not at 24 hours. Trade-offs between the benefits and risks of dexamethasone in this situation are uncertain.
Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: EBV DNA Screening for Nasopharyngeal Carcinoma (free)
Commentaries: Can a ‘liquid biopsy’ detect cancer and save lives? – STAT (free) AND Liquid Biopsy Passes Test for Nasopharyngeal Cancer – MedPage Today (free registration required) AND Early Detection of Nasopharyngeal Cancer With EBV DNA – Medscape (free registration required) AND Plasma Epstein–Barr virus DNA useful for nasopharyngeal carcinoma screening – 2 Minute Medicine (free)
Effectiveness of Tympanostomy Tubes for Otitis Media: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Commentary: Weigh Risks/Benefits of Tympanostomy Tubes: Researchers – Medscape (free registration required)
Source: EvidenceAlerts (free resource to find articles of interest)
“Tympanostomy tubes improve hearing at 1 to 3 months compared with watchful waiting, with no evidence of benefit by 12 to 24 months”
Commentary: Early Detection Improved Vocabulary Scores in Kids with Hearing Loss – MedPage Today (free registration required)
Personal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise – JAMA (link to abstract – $ for full-text)
The Jama Network – For the Media: Certain OTC, less expensive hearing aids provide benefit similar to conventional hearing aid (free)
Commentaries: Less Expensive Hearing Devices May Work as Well as Traditional Hearing Aids – Physician’s First Watch (free) AND Study Boosts Case for OTC Hearing Aids – MedPage Today (free registration required) AND OTC Hearing Devices Effective Alternative for Some, Study Shows – Medscape (free registration required)
“Some over-the-counter sound amplification devices are nearly as effective as prescription hearing aids, according to a small JAMA study” (from Physician’s First Watch)
Invited commentary: Ménière’s disease: damaged hearing but reduced vertigo – The Lancet (free)
See also: Balance retraining tool used in the study (free)
Commentaries: Online Rehabilitation Program Reduces Chronic Dizziness – Medscape (free registration required) AND Online Intervention Could Reduce Chronic Dizziness – Physician’s First Watch (free)
Editorial 1: The USPSTF Recommendation on Thyroid Cancer Screening: Don’t “Check Your Neck” (free)
Editorial 2: Cancer Screening, Overdiagnosis, and Regulatory Capture (free)
Editorial 3: How to Look for Thyroid Cancer (free)
Commentaries: No Symptoms, No Thyroid Screening, Says USPSTF – Medscape (free registration required) AND Don’t Screen For Thyroid Cancer, Task Force Says – NPR Health News (free) AND USPSTF Says No to Thyroid Cancer Screening – MedPage Today (free registration required)
The USPSTF recommended against screening for thyroid cancer in asymptomatic adults with “grade D” recommendation (Grade D = “The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits”).
Invited commentary: Surgical Site Infection Prevention – What We Know and What We Do Not Know – JAMA Surgery (free)
Commentary: ‘Long-Awaited’ CDC Guidelines on SSI Prevention Released – Medscape (free registration required)
Mortality Trends After a Voluntary Checklist-based Surgical Safety Collaborative – Annals of Surgery (link to abstract – free PDF available)
Sources: Global Health NOW Newsletter (free) AND South Carolina Hospitals Saw Surgery Deaths Drop After Implementing WHO Checklist – AJMC News (free) AND A simple checklist prevents deaths after surgery, a large new study suggests – The Washington Post (a few articles per month are free)
See also: WHO Surgical Safety Checklist – World Health Organization (free) AND A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population – New England Journal of Medicine (free)
Browse Appropriateness Criteria Topics (free)
This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.
Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ required for full-text)
See also: SWISH Four Times a Day to Keep Oral Mucositis Away – Medscape (free registration required)
This simple and inexpensive treatment resulted in a more than ten-times reduction in the incidence of grade 2 or higher stomatitis.