Nonpowder Firearm Injuries to Children Treated in Emergency Departments – Pediatrics (free)
Commentaries: Pediatric eye injuries from nonpowder firearms – Nationwide Children’s Hospital (free) AND BB guns dangerous for kids as they increase risk of eye injuries – News Medical (free) AND Overall childhood injuries from nonpowder firearms are decreasing, eye injuries are increasing – 2 Minute Medicine (free)
Related: Neurosurgical Care of Nonpowder Firearm Injuries: A Narrative Review of the Literature – Emergency Medicine International (free)
Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Bedside optic nerve ultrasonography may be useful for measuring intracranial pressure – ACP Hospitalist (free) AND Optic Nerve Ultrasound May ID Increased Intracranial Pressure – Physician’s Briefing (free)
Related Commentary on Twitter
Researchers from @McMasterU found bedside optic nerve ultrasound holds promise for diagnosing increased intracranial pressure in children and adults https://t.co/6Kx40JQuG1. pic.twitter.com/xECX6eyq1s
— Annals of Int Med (@AnnalsofIM) November 19, 2019
Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy – Arthritis & Rheumatology (link to abstract – $ for full-text)
Commentaries: Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus – Physician’s Weekly (free) AND Monitoring blood hydroxychloroquine levels beneficial in SLE – Medwire News (free)
Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Anti-CD19 MAb Trial Halted Early for Benefit in NMO – Medscape (free registration required)
World report on vision – World Health Organization (free PDF)
News Release: WHO launches first World report on vision – World Health Organization (free)
See also: Executive Summary (free PDF) AND Infographic (free PDF)
Commentaries: Aging and population growth, challenges for vision care: WHO report – Devex (free) AND Simple eye care could improve sight of more than 1 billion people – report – The Guardian (free)
Antibiotics for trachoma – Cochrane Library (free)
Summary: Antibiotics for trachoma – Cochrane Library (free)
Artificial intelligence and deep learning in ophthalmology – British Journal of Ophthalmology (free)
Related: Performance of a Deep-Learning Algorithm vs Manual Grading for Detecting Diabetic Retinopathy in India – JAMA Ophthalmology (free) AND Google Launches Program in India to Screen Diabetics for Eye Conditions (studies and commentaries on the subject)
Effect of Corticosteroid-Sparing Treatment With Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients With Uveitis: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: Antimetabolite Therapy for Uveitis: Methotrexate or Mycophenolate? – JAMA Ophthalmology (free for a limited period) AND Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial – NIH News Releases (free)
A British Teenager is Blind, But Not Because of Junk Food or “Fussy Eating” – Science-Based Medicine (free)
Original Case Report: Blindness Caused by a Junk Food Diet – Annals of Internal Medicine ($ for full-text)
Other Commentaries: Teenager ‘blind’ from living off crisps and chips – BBC (free) AND Teenage boy goes blind after existing on Pringles, white bread and french fries – CNN (free)
Effectiveness of Nursing Interventions to Prevent Dry Eye in Critically Ill Patients – American Journal of Critical Care (link to abstract – $ for full-text)
Source: Medscape
Related: Google Launches Program in India to Screen Diabetics for Eye Conditions (studies and commentaries on the subject)
Prevalence and Cost of Care Cascades After Low-Value Preoperative Electrocardiogram for Cataract Surgery in Fee-for-Service Medicare Beneficiaries – JAMA Internal Medicine (free for a limited period)
Commentary: Cascades Of Care – American Council on Science and Health (free)
Related: Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery (link to abstract and commentary) AND Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery (free)
Related Commentary on Twitter (thread – click for more)
Excited to share our work in @JAMAInternalMed TLDR: We looked at downstream cascades of care after low-value preoperative EKG for cataract surgery. 5-11 events/100 patients in following 90 days cost 10x more than initial EKGs. THREAD (1/7) https://t.co/LFYDsi7uyM #ARM19
— Ishani Ganguli MD, MPH (@IshaniG) June 3, 2019
Effect of Initial Management With Aflibercept vs Laser Photocoagulation vs Observation on Vision Loss Among Patients With Diabetic Macular Edema Involving the Center of the Macula and Good Visual Acuity: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Patients With Good Vision and Diabetic Macular Edema Involving the Center of the Macula: To Treat or Not to Treat? (free)
Commentary: Watchful waiting reasonable for patients with diabetic macular edema and good vision – NIH News Releases (free)
See also: Visual Abstract
Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery at a Safety-Net Health System – JAMA Internal Medicine (free for a limited period)
Commentary: Cataract Surgery: QI Initiative Markedly Reduced Low-Value Preoperative Care – MedicalResearch.com (free)
Related: Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery (free)
Google launches India program to screen diabetics for eye conditions that can cause blindness – CNBC (free)
See also: Launching a powerful new screening tool for diabetic eye disease in India – Verily (free) AND Google, Verily develop AI algorithm to detect diabetic eye disease from imaging exams – HealthImaging (free)
Related Studies: Clinically Applicable Deep Learning for Diagnosis and Referral in Retinal Disease (free study and commentaries) AND Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes – JAMA (free) AND Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning (link to abstract and commentaries)
Quality Standard: Serious Eye Disorders – National Institute for Health and Care Excellence (free)
Related Guideline: Glaucoma: diagnosis and management – National Institute for Health and Care Excellence (free)
Commentary: How often should patients with T2D be screened for retinopathy? – Univadis (free registration required)
Related: Evidence‐based Guidelines for Screening of Diabetic Retinopathy (free)
“This review supports lengthening of the screening interval of patients with Type 2 diabetes without retinopathy at last screening session”
Evidence‐based Danish guidelines for screening of diabetic retinopathy – Acta Ophthalmologica (free)
“There is solid evidence to support a flexible, individualized screening regimen. In particular, it is possible to prolong screening intervals to 24–48 months for patients with no or mild nonproliferative diabetic retinopathy”.
Routine preoperative medical testing for cataract surgery – Cochrane Library (free)
Summary: Routine preoperative medical testing for cataract surgery – Cochrane Library (free)
Related Perspective: A Preoperative Medical History and Physical Should Not Be a Requirement for All Cataract Patients – Journal of General Internal Medicine (free)
Related Research: Preoperative Medical Testing in Medicare Patients Undergoing Cataract Surgery – New England Journal of Medicine (free)
“This review has shown that routine preoperative testing does not increase the safety of cataract surgery.”
Clinically applicable deep learning for diagnosis and referral in retinal disease – Nature Medicine (free for a limited period)
Commentaries: Opening the ‘black box,’ Google DeepMind AI system diagnoses eye diseases and shows its work – STAT (free) AND Artificial intelligence tool ‘as good as experts’ at detecting eye problems – The Guardian (free)
Association of Cataract Surgery With Traffic Crashes – JAMA Ophthalmology (link to abstract – $ for full-text)
Commentaries: Cataract surgery tied to lower risk of car crashes – Reuters (free) AND Cataract Surgery Tied to Slight Reduction in Car Crashes – Physician’s First Watch (free)
Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography – JAMA Neurology (free for a limited period)
Commentaries: Eye Sign of Dementia Risk? Thinning of Retinal Nerve Fiber Layer – MedicalResearch.com (free) AND Are the Eyes Windows to Early Dementia? – MedPage Today (free registration required)
“A thinner Retinal Nerve Fiber Layer is associated with worse cognitive function in individuals without a neurodegenerative disease as well as greater likelihood of future cognitive decline”.
Education and myopia: assessing the direction of causality by mendelian randomization – The BMJ (free)
Editorial: Intense schooling linked to myopia (free)
Commentaries: Education and myopia: assessing the direction of causality by mendelian randomization – The BMJ Opinion (free) AND Myopia could be linked to longer periods spent in education – OnMedica (free) AND Highly Educated, Very Nearsighted? – The New York Times (10 articles per month are free)
See also: Summary of recommendations for clinicians and policy-makers (free)
Commentaries: Screening for impaired vision in older adults: New Canadian guideline – Canadian Medical Association Journal, via EurekAlert (free) Canadian Guideline Recommends Against Vision Screening of Older Adults in Primary Care Settings – NEJM Physician’s First Watch (free)
A Simple Way to Improve a Billion Lives: Eyeglasses – The New York Times (10 articles per month are free)
“It’s the biggest health crisis you’ve never heard of. Doctors, philanthropists and companies are trying to solve it”.
Uveal Effusion After Immune Checkpoint Inhibitor Therapy – JAMA Ophthalmology (link to abstract – $ for full-text)
Commentary: Ophthalmologists link immunotherapy with a serious eye condition – eCancer News (free)
n−3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease – New England Journal of Medicine (free for a limited period)
Commentaries: Omega-3s From Fish Oil Supplements No Better Than Placebo for Dry Eye – NIH, National Eye Institute (NEI), via NewsWise (free) AND Fish oil capsules don’t help dry eye symptoms, study finds – STAT (free) AND Fish oil supplements ineffective against dry eye – Reuters (free)
Association of Vitamin A Supplementation With Disease Course in Children With Retinitis Pigmentosa – JAMA Ophthalmology (free for a limited period)
Commentary: Vitamin A Slows Progression of Retinitis Pigmentosa in Kids – MedPage Today (free registration required)
Doctors just used a brand new gene therapy to try to save a child’s vision – VOX (free)
“There is a catch: It costs $850,000”.
Grader Variability and the Importance of Reference Standards for Evaluating Machine Learning Models for Diabetic Retinopathy – Ophthalmology (link to abstract – $ for full-text)
Commentary: Google’s AI program: Building better algorithms for detecting eye disease – ScienceDaily (free)
Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning – Nature Biomedical Engineering (link to abstract – $ for full-text) (via @EricTopol see Very interesting Tweet)
Commentaries: Assessing Cardiovascular Risk Factors with Computer Vision – Google Research Blog (free) AND Google’s new AI algorithm predicts heart disease by looking at your eyes – TheVerge (free) AND Combination of AI, eye images could predict cardiovascular disease – Cardiovascular Business (free) AND It’s All in the Eyes: Google AI Calculates Cardiovascular Risk From Retinal Images – Medium (free)
Artificial Intelligence Promising for CA, Retinopathy Diagnoses – Physician’s Weekly (free)
Original Article 1: Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer – JAMA (link to abstract – $ for full-text) AND Commentary: Findings Show Potential Use of Artificial Intelligence in Detecting Spread of Breast Cancer – The JAMA Network (free)
Original Article 2: Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes – JAMA (link to abstract – $ for full-text) AND Commentary: Artificial Intelligence Detects Diabetic Retinopathy and Related Eye Diseases among Patients with Diabetes – The JAMA Network (free)
NICE Guideline: Cataracts in adults: management (free)
News release: Take a patient-centred approach to treating cataracts, says NICE (free)
Invited commentary: Global causes of vision loss in 2015: are we on track to achieve the Vision 2020 target? (free)
Related study: Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis – The Lancet Global Health (free) AND Invited Commentary: Universal eye health: are we getting closer? (free)
Association of Vision Loss With Cognition in Older Adults – JAMA Ophthalmology (link to abstract – $ for full-text)
Commentaries: Vision and Hearing Loss Are Tied to Cognitive Decline – The New York Times (10 articles per month are free) AND Visual impairment among older adults associated with poor cognitive function – Medical News Today (free)
USPSTF Recommendation Summary: Vision in Children Ages 6 Months to 5 Years: Screening (free)
Editorials: The 2017 US Preventive Services Task Force Report on Preschool Vision Screening – JAMA Ophthalmology (free) AND Vision Screening in Very Young Children—Making Sense of an Inexorable Diagnostic Process – JAMA Pediatrics (free)
Author interview: USPSTF Recommendation: Vision Screening in Children (free audio)
News release: Antioxidant vitamin and mineral supplements to slow down the progression of age-related macular degeneration (AMD) – Cochrane Library (free)
Related news release: Taking vitamin supplements may slow down the progression of a common eye disease – Cochrane Library (free)
Original articles: Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration – Cochrane Library (link to abstract – $ for full-text) AND Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration – Cochrane Library (link to abstract – $ for full-text)
Commentary: Antioxidants No Help for Age-Related Macular Degeneration – MedPage Today (free registration required)
Invited commentary: Universal eye health: are we getting closer? (free)
“Blindness is set to rise at an alarming rate reaching 115 million by 2050” (RT @UniMelbMDHS see Tweet)
Review: Endophthalmitis – Korean Journal of Ophthalmology (free)
Diabetic retinopathy: current understanding, mechanisms, and treatment strategies – JCI Insight (free)
“It affects 100 M people WW, but under-diagnosed/treated: excellent review of diabetes retinopathy” (RT @EricTopol see Tweet)
Obstructive Sleep Apnoea and Retinopathy in Patients with Type 2 Diabetes: A Longitudinal Study – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Patients with Type 2 diabetes and OSA found to be at greater risk of developing diabetic retinopathy – News Medical (free)
Commentaries: Zika: Check All Potentially Exposed Infants for Eye Damage – Medscape (free registration required) AND Which Infants Exposed to Zika Virus Infection in Pregnancy Should Have Eyes Examined? – The JAMA Network (free)
“All infants with potential Zika virus exposure should have ophthalmic screening regardless of other abnormalities” (RT @PreetiNMalani see Tweet)
The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 1) – By Luke Oakden-Rayner (RT @pash22 see Tweet)
Original article: Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA (free)
See more on the impact of artificial intelligence in healthcare in our April 28th issue, see #1, and in our April 10th issue, see #8
The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 2) – By Luke Oakden-Rayner (RT @pash22 see Tweet)
Original article: Dermatologist-level classification of skin cancer with deep neural networks – Nature (link to abstract – $ for full-text)
See more on the impact of artificial intelligence in healthcare in our April 28th issue, see #1, and in our April 10th issue, see #8
Automated Identification of Diabetic Retinopathy Using Deep Learning – Ophthalmology (free)
Source: Artificial Intelligence Shows Potential to Fight Blindness – NewsWise (free)
Related article: Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA (link to abstract -$ for full-text)
Another study showing an artificial intelligence-based algorithm can be used with high reliability to screen for diabetic retinopathy, with cases referred to an ophthalmologist for further evaluation and treatment.
See more about how doctors might be affected by artificial intelligence in our April 10 issue, see #8.
Frequency of Evidence-Based Screening for Retinopathy in Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
See also: Researchers Propose Extending Diabetic Retinopathy Screening Interval – Physician’s First Watch (free) AND Research from long-term study advocates individualized eye screenings in type 1 diabetes – Diabetes.co.uk (free)
In patients who have had type 1 diabetes for 5 years, annual retinal examinations are currently recommended. Based on their findings, the authors suggest an individualized screening schedule, with less frequent screening for patients at low risk and more frequent screening for patients at higher risk, leading to decreased cost without delaying the diagnosis of clinically significant disease.
Here’s why one tech investor thinks some doctors will be ‘obsolete’ in five years – CNBC (free) (RT @CMichaelGibson)
According to this point of view, radiologists will be the first ones that are affected by Artificial Intelligence. As we can see below, other specialists that work by interpreting medical images may follow, like dermatologists, ophthalmologists and pathologists.
See also: If You Look at X-Rays or Moles for a Living, AI Is Coming for Your Job – Wired (free) AND Adapting to Artificial Intelligence: Radiologists and Pathologists as Information Specialists – JAMA Viewpoint (free – and legal – PDF found with Unpaywall) AND Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA Internal Medicine (link to abstract – $ required for full-text) AND Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features – Nature(free) see commentary in Computers trounce pathologists in predicting lung cancer type, severity, researchers find – Science News (free)
ACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)
Browse Appropriateness Criteria Topics (free)
Source: Newswise
This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.
Implementation and Evaluation of a Large-Scale Teleretinal Diabetic Retinopathy Screening Program in the Los Angeles County Department of Health Services – JAMA Internal Medicine (free) (RT @PreetiNMalani)
Editorial: Seeing the Effect of Health Care Delivery Innovation in the Safety Net (free)
A large-scale telemedicine diabetic retinopathy screening program increased overall rates of screening by 16.3%, and wait times for screening were reduced by 89.2%.