Oncology

NCCN Guideline: Distress Management

10 Oct, 2019 | 09:06h | UTC

ESMO Guideline: Thyroid Cancer

7 Oct, 2019 | 00:52h | UTC

Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline – The BMJ (free)

Editorial: Personalised and risk based cancer screening (free)

Related Study: Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study – The BMJ (free)

Commentaries: Guideline Moves Away from Colorectal Cancer Screening for Some – NEJM Journal Watch (free) AND First Guideline to Say Colon Cancer Screening Is Not for All – Medscape (free registration required)

Related Guidelines: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)

 

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Global Burden of Cancer, 1990 to 2017

30 Sep, 2019 | 00:42h | UTC

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study – JAMA Oncology (free)

 

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Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Skin cancer: Half of people surviving advanced melanoma – BBC (free) AND Combination immunotherapy drugs herald new hope for melanoma patients with long term survival rates – The Royal Marsden NHS Foundation Trust (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

 

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Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Two immunotherapy drug combination offers chemotherapy-free option for advanced NSCLC – European Society for Medical Oncology (free) AND Nivolumab/Low-dose Ipilimumab: A Potential Chemotherapy-Sparing Option in Advanced NSCLC – Pharmacy Times (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

 

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Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy – JACC CardioOncology (free)

 

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Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers – Nature Medicine (link to abstract – $ for full-text)

Commentary: Liquid biopsies reveal genetic alterations linked to cancer drug resistance – Broad Institute of MIT and Harvard (free)

 

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Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (ICBP SURVMARK-2): a population-based study – The Lancet Oncology (free)

Commentaries: Cancer Patients in Rich Countries Are Gaining Years, Study Shows – Bloomberg (free) AND Cancer survival in high income countries is improving but international disparities persist – eCancer News (free)

 

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Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial – The BMJ (free)

 

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NCCN Guidelines Insights: Ovarian Cancer

18 Aug, 2019 | 21:30h | UTC

Cancer statistics for adults aged 85 years and older, 2019 – CA: A Cancer Journal for Clinicians (free)

Commentary: Cancer in Adults Aged 85 and Older: Rates, Screening, and Survival – The ASCO Post (free)

 

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Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

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NCCN Guideline: Adult Cancer Pain

9 Aug, 2019 | 08:12h | UTC

Comparison of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy With Systematic Biopsy Alone for the Diagnosis of Prostate Cancer: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: The Evolving Paradigm of Prostate Cancer Screening – JAMA Network Open (free) AND MRIs Improve Targeting of Biopsies for Prostate Cancer Diagnosis – MedicalResearch.com (free)

Related Cochrane Review: MRI Pathway vs. Systematic Biopsy for Detecting Prostate Cancer (free)

“Prebiopsy magnetic resonance imaging combined with targeted biopsy is associated with improved detection of clinically significant prostate cancer and reduced numbers of biopsy cores per procedure, while potentially avoiding unnecessary biopsies.”

 


The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017 – The Lancet Oncology (free)

Commentaries: Global burden of childhood cancer: growing, but controllable – The Lancet Oncology (free) AND Globally, more than 11 million years of healthy life lost due to childhood cancer in 2017 – The Lancet (free)

 

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Doctors: How Job Stress Can Age Us

31 Jul, 2019 | 01:59h | UTC

Choosing Wisely India: ten low-value or harmful practices that should be avoided in cancer care – The Lancet Oncology (free registration required)

Commentary: 10 Ways to Improve the Value of Cancer Care – Medscape (free registration required)

See other lists of low-value practices in oncology:

– American Society of Clinical Oncology

– Society of Surgical Oncology

– Society of Gynecologic Oncology

– American Society for Radiation Oncology

– Medical Oncology Group of Australia

– Oncology – Choosing Wisely Canada

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

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Assessment of Deep Natural Language Processing in Ascertaining Oncologic Outcomes From Radiology Reports – JAMA Oncology (free for a limited period)

Commentaries: The Tipping Point for Deep Learning in Oncology – JAMA Oncology (free for a limited period) AND Deep Natural Language Processing of Oncology Radiology Reports – The ASCO Post (free)

 

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2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Does Size of Surgical Excision Margins for Thick Localized Cutaneous Melanoma Affect Survival Outcomes? – The ASCO Post (free) AND Quick Take: 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm – 2 Minute Medicine (free)

 

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The Promise and Price of Cellular Therapies – The New Yorker (a few articles per month are free)

“New “living drugs”—made from a patient’s own cells—can cure once incurable cancers. But can we afford them?”

 


MRI versus mammography for breast cancer screening in women with familial risk (FaMRIsc): a multicentre, randomised, controlled trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: MRI Breast Screening Better for Women With Familial Cancer Risk – MedPage Today (free registration required)

 

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NCCN Guideline: Acute Myeloid Leukemia

2 Jul, 2019 | 01:16h | UTC

Estimation of Kidney Function in Oncology: Implications for Anticancer Drug Selection and Dosing – Clinical Journal of the American Society of Nephrology (free)

“In one retrospective study, approximately one half of kidney function–impaired patients with solid tumors who were receiving a drug that necessitated dose adjustments for kidney function received almost 50% of their prescriptions at standard doses”.

 


Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 

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ESMO Guideline: Early Breast Cancer

24 Jun, 2019 | 01:49h | UTC

Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”

 


Randomized Trial of Lisinopril Versus Carvedilol to Prevent Trastuzumab Cardiotoxicity in Patients With Breast Cancer – Journal of the American College of Cardiology (link to abstract – $ for full-text)

“In patients with HER2-positive breast cancer treated with trastuzumab, both lisinopril and carvedilol prevented cardiotoxicity in patients receiving anthracyclines.”

 


Cancer Control in Low- and Middle-Income Countries: Is It Time to Consider Screening? – Journal of Global Oncology (free)

“the placement of priority on early detection cannot be assumed to be effective in LMICs, where limited downstream resources may be overwhelmed by the inevitable increases in number of diagnoses.”

 


Effect of Vein-First vs Artery-First Surgical Technique on Circulating Tumor Cells and Survival in Patients With Non–Small Cell Lung Cancer: A Randomized Clinical Trial and Registry-Based Propensity Score Matching Analysis – JAMA Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts

 

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