Neurosurgery
Prehospital guidelines for the management of traumatic brain injury
24 Apr, 2023 | 13:45h | UTC
RCT | Stereotactic radiosurgery vs. conventional radiotherapy for localized vertebral metastases of the spine
24 Apr, 2023 | 13:37h | UTCStereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine: Phase 3 Results of NRG Oncology/RTOG 0631 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Audio interview: Radiosurgery of Spine Metastasis—NRG/RTOG 0631 RCT Final Results – JAMA
Commentary on Twitter
Phase 3 rand trial of spinal radiosurgery vs. conventional external beam radiation therapy for pts w/spinal metastases showed radiosurgery did not significantly improve pain response at 3mo but showed feasibility that makes it widely used today. https://t.co/LvZY1nbUpS #RadOnc
— JAMA Oncology (@JAMAOnc) April 20, 2023
Cohort Study | Prehospital end-tidal CO2 levels and mortality in suspected severe traumatic brain injury patients
24 Apr, 2023 | 13:35h | UTCEditorial: Prehospital ventilation targets in severe traumatic brain injury – Intensive Care Medicine
Commentary on Twitter
Prehospital etCO2 in severe #TBI, BRAIN-PROTECT study
? L-shaped association with mortality
? 35-45 mmHg seems reasonable target: lower ETCO2? sharp mortality ⬆️
?️ https://t.co/DC0DoHa00NWith editorial on MV targets & reliability of available data
?️ https://t.co/jVZ4zZVHxv pic.twitter.com/74vKxjyGpA— Intensive Care Medicine (@yourICM) April 20, 2023
Cohort Study | Major cardiovascular events after spontaneous intracerebral hemorrhage by hematoma location
12 Apr, 2023 | 13:13h | UTCInvited Commentary: Major Adverse Cardiovascular Events After Intracerebral Hemorrhage—It’s All About Location, Location, Location – JAMA Network Open
RCT | Drain usage may increase the length of hospital stay following lumbar arthrodesis
31 Mar, 2023 | 13:18h | UTCCommentary: Wound drains increase hospital los after lumbar surgery? – Orthopedics This Week
Expanding Organ Usage: UK study finds organs from patients with a primary brain tumor are a viable option
27 Mar, 2023 | 13:27h | UTCSummary: A national cohort study in the UK investigated the risk of cancer transmission from deceased donors with primary brain tumors to organ recipients. The study found no cases of brain tumor transmission among 778 transplants from 282 donors with primary brain tumors, including 262 from donors with high-grade tumors. Organ transplant survival was equivalent to that in matched controls, and some organs from donors with high-grade tumors were less likely to be transplanted.
The results suggest that the risk of cancer transmission in transplants from deceased donors with primary brain tumors is lower than previously thought. Furthermore, the study indicated that donors with brain tumors provided good-quality organs with favorable risk markers and excellent transplant outcomes. Some organs from donors with high-grade tumors were underutilized, indicating a possible aversion by transplant clinicians or patients to use these organs.
These findings imply that it may be possible to safely expand organ usage from donors with primary brain tumors without negatively impacting outcomes, potentially benefiting many patients waiting for a transplant. Although this might lead to a slight rise in transplant numbers in the UK, the findings may hold particular significance for nations with stricter guidelines, such as the United States. The study’s findings can help transplant clinicians discuss the risks and benefits of accepting organ offers from such donors.
Cohort Study | Functional recovery, symptoms, and quality of life 1 to 5 years after traumatic brain injury
24 Mar, 2023 | 12:52h | UTC
Review | Neuromonitoring in critically ill patients
20 Mar, 2023 | 13:18h | UTCNeuromonitoring in Critically Ill Patients – Critical Care Medicine (free for a limited period)
Related: The importance of neuromonitoring in non-brain injured patients – Critical Care
Review | Neurogenic shock: definition, identification, and management in the ED
20 Mar, 2023 | 13:09h | UTCNeurogenic Shock: Definition, Identification, and Management in the ED – emDocs
M-A | Endoscopic surgery for spontaneous supratentorial intracerebral hemorrhage
16 Mar, 2023 | 13:04h | UTC
Global validation of the AO Spine Upper Cervical Injury Classification
16 Mar, 2023 | 12:58h | UTCGlobal Validation of the AO Spine Upper Cervical Injury Classification – Spine
Consensus Recommendations | Spinal tumors
9 Mar, 2023 | 14:15h | UTC
SR | Spinal cord stimulation for low back pain provides no sustained clinical benefits compared to placebo
9 Mar, 2023 | 14:12h | UTCSummary: Spinal cord stimulation (SCS) is a surgical procedure used to treat persistent low back pain by sending electrical signals via implanted electrodes into the spinal cord. The review included 13 studies (randomized controlled trials and cross‐over trials) with 699 participants.
Most of the studies were focused on short-term effects (less than one month), but the review found it is uncertain whether spinal cord stimulation can improve outcomes in the immediate term compared with placebo. At six months, SCS probably does not improve back or leg pain, function, or quality of life compared with placebo, with moderate certainty of evidence. Adverse events were also reported, including infections, neurological damage, and lead migration requiring repeated surgery.
The review concluded that the data does not support the use of SCS to manage low back pain outside a clinical trial. Current evidence suggests SCS probably does not have sustained clinical benefits that would outweigh the costs and risks of this surgical intervention.
Article: Spinal cord stimulation for low back pain – Cochrane Library
Summary: Spinal cord stimulation for low back pain – Cochrane Library
Commentary from the author on Twitter
Our Cochrane review on spinal cord stimulators for #backpain out today.
Bottom line:
-Mod certainty evidence of no benefit vs placebo in medium term
-Uncertain if benefit on pain in immediate term
-Adverse events (infection, re-operation) commonhttps://t.co/lNJQeN96Zs— Adrian Traeger (@adrian_traeger) March 7, 2023
Cohort Study | Lifetime traumatic brain injury and cognitive domain deficits in late life
2 Mar, 2023 | 12:45h | UTCLifetime Traumatic Brain Injury and Cognitive Domain Deficits in Late Life: The PROTECT-TBI Cohort Study – Journal of Neurotrauma (link to abstract – you can try this link for full-text)
News Release: Three or more concussions linked with worse brain function in later life – University of Exeter
Review | Glioblastoma and other primary brain malignancies in adults
24 Feb, 2023 | 13:54h | UTCArticle: Glioblastoma and Other Primary Brain Malignancies in Adults: A Review – JAMA (free for a limited period)
Audio clinical review: Glioblastoma and Other Primary Brain Malignancies in Adults – JAMA
Commentary on Twitter
Review summarizes current evidence regarding diagnosis and treatment of primary malignant brain tumors in adults. https://t.co/pNKio61bN5
— JAMA (@JAMA_current) February 21, 2023
Consensus Paper | Early management of isolated severe traumatic brain injury in a hospital without neurosurgical capabilities
24 Feb, 2023 | 13:49h | UTC
Commentary from the author on Twitter
Great to see our consensus published. Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES).https://t.co/k9hwI82dOW pic.twitter.com/pIp5gFRnPa
— Deepak Sharma (@deepak_neuro) January 14, 2023
Guideline | Diagnosis and management of subarachnoid hemorrhage caused by a ruptured aneurysm
16 Feb, 2023 | 15:23h | UTC
SR | Preoperative medical treatments and surgical approaches for acromegaly
15 Feb, 2023 | 15:48h | UTC
Consensus Statement | Development of an Enhanced Recovery After Surgery (ERAS) surgical safety checklist
10 Feb, 2023 | 14:03h | UTC
Commentary from the author on Twitter (thread – click for more)
The @WHO Surgical Safety Checklist and the @ErasSociety guidelines come together.?
#ERAS teams can leverage 2 tools in 1 to improve care in critical perioperative communication moments https://t.co/EaXYyj7b56
via @JAMANetworkOpen part of @JAMANetwork pic.twitter.com/WHJMjThubO— Mary Brindle (@MaryEBrindle) February 8, 2023
INCOG 2.0 Guidelines for cognitive rehabilitation following traumatic brain injury
9 Feb, 2023 | 13:47h | UTCINCOG 2.0 Guidelines for Cognitive Rehabilitation Following Traumatic Brain Injury – The Journal of Head Trauma Rehabilitation
What’s Changed From 2014 to Now?
Methods, Overview, and Principles
Part II: Attention and Information Processing Speed
Part IV: Cognitive-Communication and Social Cognition Disorders
Spinal cord injury: the global incidence, prevalence, and disability from the Global Burden of Disease Study 2019
9 Feb, 2023 | 13:20h | UTCCommentary: Measures needed to combat growing incidence and burden of spinal cord injury – Spinal News International
Review | Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury
7 Feb, 2023 | 13:32h | UTC
M-A | Depressive symptoms in individuals with persistent postconcussion symptoms
3 Feb, 2023 | 13:48h | UTCCommentary: Significant Link Seen for Persistent Postconcussion Symptoms, Depression – HealthDay
Commentary on Twitter
Patients with persistent postconcussion symptoms are at increased risk of experiencing symptoms of depression. Post-injury support and interventions targeting mental health are necessary for optimal outcomes. https://t.co/7KiletIsf6
— JAMA Network Open (@JAMANetworkOpen) December 27, 2022
Derivation and validation of a clinical prediction rule for upper limb functional outcomes after traumatic cervical spinal cord injury
31 Jan, 2023 | 13:34h | UTC
Commentary on Twitter
This clinical prediction rule for prognosis of patients with cervical spinal cord injuries uses sub-acute neurological data to predict upper limb recovery; this may guide early treatment decisions, eg. reconstructive surgeries and acute clinical trials. https://t.co/hjE0v1EtuJ
— JAMA Network Open (@JAMANetworkOpen) December 21, 2022
RCT | Duration of prophylactic levetiracetam after surgery for brain tumor
27 Jan, 2023 | 12:06h | UTC
Commentary on Twitter
#NEULatestArticle #NEUVisualAbstract Duration of Prophylactic Levetiracetam After Surgery for Brain Tumor: A Prospective Randomized Trial https://t.co/O8wAgwK0SL by Rahman et al @UFHealth @CNS_Update @DKondziolkaCNS @IsaacYangMD #Seizures #BrainTumor pic.twitter.com/ALVEw91oiZ
— Neurosurgery Publications (@NeurosurgeryCNS) October 6, 2022