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Neurology

RCT | Mild hypercapnia after cardiac arrest shows no improvement in neurological outcomes vs. normocapnia

16 Jun, 2023 | 14:15h | UTC

Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: New data supports current management of CO2 levels in cardiac arrest patients – UCD Dublin

 


Consensus Statement | Concussion in sport

15 Jun, 2023 | 15:14h | UTC

Consensus statement on concussion in sport: the 6th International Conference on Concussion in Sport–Amsterdam, October 2022 – British Journal of Sports Medicine

News Release: International expert panel revises management of concussion in sport for optimal care of athletes at all levels of participation – BMJ

 


Evidence-based clinical practice guideline for deprescribing opioid analgesics

15 Jun, 2023 | 15:08h | UTC

Evidence-based clinical practice guideline for deprescribing opioid analgesics – University of Sidney

 


Crossover RCT | THC and Cannabidiol demonstrate potential in Tourette syndrome tic management, despite cognitive impacts

14 Jun, 2023 | 14:27h | UTC

Tetrahydrocannabinol and Cannabidiol in Tourette Syndrome – NEJM Evidence

 


RCT | Valbenazine outperforms placebo in alleviating chorea in Huntington’s disease

14 Jun, 2023 | 14:18h | UTC

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington’s disease (KINECT-HD): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)

News Release: Valbenazine improves chorea associated with Huntington’s disease – News Medical / University of Texas Health Science Center at Houston

 


RCT | Multivitamin supplementation may improve memory in aged adults

7 Jun, 2023 | 14:12h | UTC

Multivitamin Supplementation Improves Memory in Older Adults: A Randomized Clinical Trial – The American Journal of Clinical Nutrition (link to abstract – $ for full-text)

News Releases:

Study finds daily multivitamin supplements improved memory and slowed cognitive aging in older adults – Brigham and Women’s Hospital

Multivitamin Improves Memory in Older Adults, Study Finds – Columbia University

Related Research: Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial – Alzheimer’s & Dementia

 


SR | Limited evidence for vitamin and mineral supplements in delaying dementia in people with mild cognitive impairment

7 Jun, 2023 | 14:09h | UTC

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment – Cochrane Library

 

Commentary on Twitter

 


RCT | Tirofiban results in greater likelihood of excellent outcome vs. aspirin in stroke without large vessel occlusion

6 Jun, 2023 | 14:33h | UTC

Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Tirofiban for Stroke Without Large or Medium Vessel Occlusion – American College of Cardiology

 

Commentary on Twitter

 


Position Paper | Continuous electroencephalography in the intensive care unit

6 Jun, 2023 | 14:29h | UTC

Continuous electroencephalography in the intensive care unit: A critical review and position statement from an Australian and New Zealand perspective – Critical Care and Resuscitation

 


Global burden, risk factors analysis, and prediction study of ischemic stroke, 1990–2030

5 Jun, 2023 | 13:53h | UTC

Global Burden, Risk Factors Analysis, and Prediction Study of Ischemic Stroke, 1990–2030 – Neurology

News Release: Worldwide Stroke Deaths Expected to Increase to Nearly 5 Million by 2030 – American Academy of Neurology

 

Commentary on Twitter

 


Review | Deprescribing interventions for gabapentinoids in adults

1 Jun, 2023 | 12:05h | UTC

Deprescribing interventions for gabapentinoids in adults: a scoping review – British Journal of Clinical Pharmacology

 


RCT | Care bundle with intensive blood pressure control improves outcomes in acute cerebral hemorrhage

30 May, 2023 | 12:04h | UTC

The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial – The Lancet

News Release: Tens of thousands of lives a year could be saved by new treatment protocol for brain hemorrhage – George Institute for Global Health

 


RCT | Preliminary evidence for right median nerve stimulation in awakening from acute traumatic coma

30 May, 2023 | 11:36h | UTC

Acute traumatic coma awakening by right median nerve electrical stimulation: a randomised controlled trial – Intensive Care Medicine

 

Commentary on Twitter

 


Review | Posterior circulation ischemic stroke diagnosis and management

30 May, 2023 | 11:30h | UTC

Posterior circulation ischaemic stroke diagnosis and management – Clinical Medicine Journal

 


AHA/ASA Guideline for the management of patients with aneurysmal subarachnoid hemorrhage

29 May, 2023 | 11:16h | UTC

2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association – Stroke

Top Things to Know: 2023 Aneurysmal Subarachnoid Hemorrhage Guideline – American Heart Association

 

Commentary on Twitter

 


RCT | Group support and skill-based learning reduce opioid use in chronic pain, but leads to no effect on pain perception

29 May, 2023 | 11:14h | UTC

Reducing Opioid Use for Chronic Pain With a Group-Based Intervention: A Randomized Clinical Trial – JAMA (free for a limited period)

See also: Visual Abstract

News Release: New treatment helps people stop addictive opioid painkillers used for chronic pain – University of Warwick

 


Guideline | Targeted temperature management in intracerebral, subarachnoid hemorrhage and acute ischemic stroke

29 May, 2023 | 10:48h | UTC

Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke: updated consensus guideline recommendations by the Neuroprotective Therapy Consensus Review (NTCR) group – British Journal of Anaesthesia

 


Advances and challenges in neuropathic pain: a narrative review and future directions

29 May, 2023 | 10:46h | UTC

Advances and challenges in neuropathic pain: a narrative review and future directions – British Journal of Anaesthesia

 


Guideline | Assessment and early management of head injury

23 May, 2023 | 13:11h | UTC

Head injury: assessment and early management – NICE

Commentary: NICE head injury guidelines 2023: Now who do we scan? – St Emilyn’s

 


M-A | Risk and benefits of wakefulness-promoting drugs in obstructive sleep apnea patients

23 May, 2023 | 12:43h | UTC

Comparative Efficacy and Safety of Wakefulness-Promoting Agents for Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea: Systematic Review and Network Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Researchers find best treatment for excessive daytime sleepiness – McMaster University

Commentary: Multiple agents effective for excessive daytime sleepiness but may be discontinued due to side effects, review finds – ACP Internist

 


Drug-induced abnormal involuntary movements: prevalence and treatment

22 May, 2023 | 13:30h | UTC

Drug-Induced Abnormal Involuntary Movements: Prevalence and Treatment – Primary care companion to CNS disorders

 


RCT | ART intensification shows no benefit in treating HIV-associated neurocognitive impairment

18 May, 2023 | 13:31h | UTC

Antiretroviral Therapy Intensification for Neurocognitive Impairment in HIV – Clinical Infectious Diseases

 


Guideline | Acute dizziness and vertigo in the emergency department

15 May, 2023 | 13:25h | UTC

Guidelines for reasonable and appropriate care in the emergency department 3 (GRACE-3): Acute dizziness and vertigo in the emergency department – Academic Emergency Medicine

News Release: New guideline for treatment of acute dizziness and vertigo in the emergency department – Society for Academic Emergency Medicine

 


RCT | Cognitive behavioral therapy proves effective for severe post-COVID-19 fatigue

15 May, 2023 | 13:16h | UTC

Efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19: results of a randomized controlled trial – Clinical Infectious Diseases

News Release: Cognitive behavioral therapy lessens post-viral fatigue after COVID-19 – Amsterdam UMC

 

Commentary on Twitter

 


RCT | Neck–shoulder region training for chronic headache in women

15 May, 2023 | 12:59h | UTC

Neck–Shoulder Region Training for Chronic Headache in Women: A Randomized Controlled Trial – Clinical Rehabilitation

 

Commentary on Twitter

 


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