Nephrology

2019 Update of the Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA–EDTA) recommendations for the management of lupus nephritis – Annals of Rheumatic Diseases

Commentary: EULAR, ERA–EDTA issue guidelines for managing lupus nephritis – Medicine Matters

Related Guidelines: Consensus of the Brazilian Society of Rheumatology for the diagnosis, management and treatment of lupus nephritis (free) AND 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus (free) AND 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus (free) AND Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus (free PDF)

Related Reviews: Update on Lupus Nephritis – Clinical Journal of the American Society of Nephrology (free) AND Immunosuppressive Treatment for Proliferative Lupus Nephritis – Cochrane Library (free) AND Induction and Maintenance Immunosuppression Treatment of Proliferative Lupus Nephritis: A Network Meta-analysis of Randomized Trials. – American Journal of Kidney Diseases (free)

 


COVID-19: Updates for Nephrologists

6 Apr, 2020 | 00:52h | UTC

Guidelines:

Articles:

COVID-19 Nephrology: This page will be updated as often as necessary and will be fixed in the right column on our homepage.

 


Management of Kidney Stones in 2020

20 Mar, 2020 | 10:54h | UTC

Association Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration Rate – JAMA Internal Medicine (free for a limited period)

Editorial: Continuation of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in the Face of Kidney Disease Progression—Safe and Possibly Life Saving (free for a limited period)

 

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Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality – Age and Ageing (free)

Commentary: Expert reaction to study looking at low blood pressure and mortality in older adults – Science Media Centre (free)

 

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Effect of dose and duration of reduction in dietary sodium on blood pressure levels: systematic review and meta-analysis of randomised trials – The BMJ (free)

Commentaries: Further evidence adds weight to call for urgent action on salt targets – George Institute for Global Health (free) AND Cutting salt likely to prevent future heart disease, even if you’re not at risk now – CNN (free)

 

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Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With Hypertension – JAMA Internal Medicine (free for a limited period)

Commentary: Antihypertensive Prescribing Cascades as High-Priority Targets for Deprescribing – JAMA Internal Medicine (free for a limited period)

 

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Effect of salt substitution on community-wide blood pressure and hypertension incidence – Nature Medicine (free for a limited period)

Commentaries Before Publication at #ESCCongress: Community-based salt substitution programme lowers blood pressure – European Society of Cardiology (free) AND Community-Level Salt-Swapping Strategy Pays Dividends in Peru – TCTMD (free)

 

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Podcast: Dialysis for the Internist

28 Jan, 2020 | 09:04h | UTC

Effect of Hydroxyethyl Starch vs Saline for Volume Replacement Therapy on Death or Postoperative Complications Among High-Risk Patients Undergoing Major Abdominal Surgery: The FLASH Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Hydroxyethyl Starch for Fluid Replacement Therapy in High-Risk Surgical Patients: Context and Caution (free for a limited period)

Related Cochrane Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People (free)

 

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NICE Guideline: Acute Kidney Injury

5 Jan, 2020 | 14:22h | UTC

Development of Risk Prediction Equations for Incident Chronic Kidney Disease – JAMA (free for a limited period)

See Calculator: Risk of Developing Reduced Kidney Function (free tool)

Editorial: Predicting Risk of Kidney Disease: Is Risk-Based Kidney Care on the Horizon? – JAMA (free for a limited period)

Commentaries: New Tool Predicts Five-Year Risk of Chronic Kidney Disease With High Accuracy – Johns Hopkins Bloomberg School of Public Health (free) AND Researchers Develop Tool to Identify Those at Risk of Future CKD – AJMC (free)

#KidneyWk – Just presented at the American Society of Nephrology Kidney Week 2019

 

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Effect of Vitamin D and Omega-3 Fatty Acid Supplementation on Kidney Function in Patients With Type 2 Diabetes: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Vitamin D and Health Outcomes: Then Came the Randomized Clinical Trials – JAMA (free for a limited period)

Commentary: Supplements don’t preserve kidney health in Type 2 diabetes – University of Washington School of Medicine (free)

#KidneyWk – Just presented at the American Society of Nephrology Kidney Week 2019

 

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A Phase 3 Trial of Difelikefalin in Hemodialysis Patients with Pruritus – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Novel Drug Eases Uremic Pruritus – Renal & Urology News (free)

#KidneyWk – Just presented at the American Society of Nephrology Kidney Week 2019

 


Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)

Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)

 

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Podcast: Hypernatremia is Easy

3 Sep, 2019 | 01:09h | UTC

Intraperitoneal Cefepime Monotherapy Versus Combination Therapy of Cefazolin Plus Ceftazidime for Empirical Treatment of CAPD-Associated Peritonitis: A Multicenter, Open-Label, Noninferiority, Randomized, Controlled Trial – American Journal of Kidney Diseases (link to abstract – $ for full-text)

 

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Comparison of the Harms, Advantages, and Costs Associated With Alternative Guidelines for the Evaluation of Hematuria – JAMA Internal Medicine (free for a limited period)

Commentaries: Hematuria Practice Guidelines That Explicitly Consider Harms and Costs – JAMA Internal Medicine (free for a limited period) AND Evaluating Hematuria: Uniform Use of CT Seen as Risky and Expensive – NEJM Journal Watch (free)

 

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Consensus Statement on Renal Denervation

14 Jul, 2019 | 19:00h | UTC

Quality Improvement Goals for Acute Kidney Injury – Clinical Journal of the American Society of Nephrology (free)

 

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Use of Directly Observed Therapy to Assess Treatment Adherence in Patients With Apparent Treatment-Resistant Hypertension – JAMA Internal Medicine (free link for a limited period)

Commentaries: Directly Observed Therapy Effective for Treatment-Resistant Hypertension – Clinical Advisor (free) AND Think it’s treatment-resistant hypertension? Your eyes need to DOT (directly observe therapy) – Univadis (free registration required)

 

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Estimation of Kidney Function in Oncology: Implications for Anticancer Drug Selection and Dosing – Clinical Journal of the American Society of Nephrology (free)

“In one retrospective study, approximately one half of kidney function–impaired patients with solid tumors who were receiving a drug that necessitated dose adjustments for kidney function received almost 50% of their prescriptions at standard doses”.

 


Risk of ESKD in Older Live Kidney Donors with Hypertension – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentary: Higher Risk of Kidney Failure in Older Donors With Hypertension – Medscape (free registration required)

 

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Use of Peripherally Inserted Central Catheters in Patients With Advanced Chronic Kidney Disease: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Peripherally inserted central catheters often used in CKD – HealthDay (free) AND Too Many CKD Patients Get Central Catheters Despite Warnings – Medscape (free registration required)

 

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Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: phase III randomised controlled trial and economic evaluation – The BMJ (free)

 

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Diagnostic Performance of Creatinine-Based Equations for Estimating Glomerular Filtration Rate in Adults 65 Years and Older – JAMA Internal Medicine (free for a limited period)

 

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Fibrillary Glomerulonephritis: An Update

30 Apr, 2019 | 02:07h | UTC

Review: Acute Management of Hyperkalemia

28 Apr, 2019 | 13:33h | UTC

Review: Hepatorenal Syndrome

24 Apr, 2019 | 06:21h | UTC