Meta-analysis: Acute Kidney Injury After Computed Tomography

21Aug
2017

Acute Kidney Injury After Computed Tomography: A Meta-analysis – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: When kidneys are injured, CT contrast isn’t the culprit – Health Imaging (free)

Related article: Risk of Acute Kidney Injury After Intravenous Contrast Media Administration – Annals of Emergency Medicine (free)

Source: Hospital Medicine Virtual Journal Club

Compared with noncontrast CT, contrast-enhanced CT was not significantly associated with either acute kidney injury, need for renal replacement therapy, or all-cause mortality.

 

Standard of Care in Critically Ill Adult Patients With Atypical Hemolytic Uremic Syndrome

17Aug
2017

Comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients

17Aug
2017

A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials – BMC Nephrology (free)

Source: Critical Care Reviews Newsletter

Early initiation of RRT in critically ill patients did not result in reduced mortality, change in renal function recovery, dependence, duration of RRT, renal recovery time, mechanical ventilation time or complications.

 

Blood pressure targets for hypertension in older adults

15Aug
2017

Blood pressure targets for hypertension in older adults – Cochrane Library (free)

Full review: Blood pressure targets for hypertension in older adults – Cochrane Library (link to abstract – $ for full-text)

Related guideline: Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From ACP and AAFP (free)

“At the present time there is insufficient evidence to know whether a higher BP target (less than150 to 160/95 to 105 mmHg) or a lower BP target (less than 140/90 mmHg) is better for older adults with high BP”

 

Ibuprofen versus placebo effect on acute kidney injury in ultramarathons

15Aug
2017

Acute Kidney Injury in Pregnancy-specific Disorders

15Aug
2017

Dual Kidney Transplantation: A Review of Past and Prospect for Future

15Aug
2017

Day-to-Day Blood Pressure Variability and Risk of Dementia

14Aug
2017

Review: Palliative and end-of-life care in nephrology

11Aug
2017

Lithium Associated With a Higher Risk of Chronic Kidney Disease in Older Adults

11Aug
2017

Lithium Use, but Not Valproate Use, Is Associated With a Higher Risk of Chronic Kidney Disease in Older Adults With Mental Illness – The Journal of Clinical Psychiatry (link to abstract -$ for full-text)

Case-control study suggests Lithium is associated with increased risk of chronic kidney disease.

 

Epidemiology, pathophysiology, and management of uric acid urolithiasis

11Aug
2017

Nephrolithiasis more common in patients with gout

10Aug
2017

Incidence of and risk factors for nephrolithiasis in patients with gout and the general population, a cohort study – Arthritis Research & Therapy (free)

Commentaries: Gout Patients Run Higher Risk of Kidney Stones – MedPage Today (free registration required) AND Gout associated with elevated risk for kidney stones – MedWire News (free)

“60% increased risk of first-time nephrolithiasis versus general population, with little protection from allopurinol” (from MedPage Today)

 

Challenges in Treating Cardiovascular Disease: Restricting Sodium and Managing Hyperkalemia

10Aug
2017

Dietary Approaches in the Management of Diabetic Patients with Kidney Disease

9Aug
2017

Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy:

3Aug
2017

Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Steroid treatment for type of kidney disease associated with increased risk for serious infections – The JAMA Network (free)

Renal outcomes seemed to be less frequent in the group using methylprednisolone (5,9% vs 15,9%), but the trial was stopped early due to a significantly increased risk of serious adverse events with oral methylprednisolone vs placebo (14.7% vs 3.2%, primarily excess infections)

 

Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors

3Aug
2017

KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors

3Aug
2017

Kidney dysfunction in patients with pulmonary arterial hypertension

3Aug
2017

Chronic kidney disease in adults – NICE Quality Standard

28Jul
2017

Updates in Management of Hyperkalemia

25Jul
2017

Biomarkers in renal transplantation: An updated review

23Jul
2017

Chronic kidney disease and the global NCDs agenda

23Jul
2017

Treatment of diabetic kidney disease: current and future targets

21Jul
2017

Rhabdomyolysis & Exertional Heat Stroke

20Jul
2017

Guideline: Asymptomatic Microscopic Hematuria in Women

18Jul
2017

Hypertensive disorders of pregnancy

17Jul
2017

Diagnosis and Management of Resistant Hypertension

11Jul
2017

Management of Small Renal Masses

10Jul
2017

Salt intake and Cardiovascular Disease

9Jul
2017

Current status of lupus nephritis

7Jul
2017

Imaging and Management of Incidental Renal Lesions

7Jul
2017

Taking anti-inflammatories during exercise may increase the risk of kidney injury

5Jul
2017

Bring On the Exercise, Hold the Painkillers – The New York Times (10 articles per month are free)

Taking anti-inflammatories during exercise may increase the risk of kidney injury.

 

Direct oral anticoagulants in patients with chronic kidney disease

3Jul
2017

Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder

25Jun
2017

Is aircraft noise exposure associated with cardiovascular disease and hypertension?

22Jun
2017

Guidelines for the Management of Hypertension

13Jun
2017

Prevention of acute kidney injury and protection of renal function in the intensive care unit

12Jun
2017

Serum uric acid levels and multiple health outcomes

8Jun
2017

Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies – The BMJ (free)

Observational studies suggest that high serum uric acid levels are associated with multiple health outcomes, including cardiovascular and metabolic diseases. This review findings suggest there is a clear association only for gout and nephrolithiasis.

 

Home blood pressure monitors inaccurate 70 percent of the time?

7Jun
2017

Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality

1Jun
2017

Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality: A Systematic Review and Network Meta-analysis – JAMA Cardiology (free) (RT @GreenlandRohan see Tweet)

Commentaries: Reducing blood pressure below recommended targets significantly reduces CVD, mortality risk – Clinical Advisor (free registration required) And New Review Supports Aggressive BP Targets – MedPage Today (free registration required)

Ideal blood pressure targets are controversial and recommendations vary across hypertension guidelines. This new meta-analysis suggests the risk of cardiovascular disease would be lowest with a systolic blood pressure between 120-124 mmHg.

 

Renal dysfunction in cirrhosis

17May
2017

Series: Acute Kidney Injury in the Intensive Care Unit

6May
2017

Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients

5May
2017

Correspondence: Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients – The New England Journal of Medicine (free)

Transplantation of HCV-infected-kidneys into uninfected recipients seems feasible in this era of direct-acting antiviral agents, maybe shortening waiting times for those willing to take the risk.

 

Global kidney health 2017 and beyond

25Apr
2017

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy – The Lancet (free registration required)

Chronic kidney disease is increasingly recognized as a global public health problem affecting as many as 10–15% of the population worldwide. It is associated with impaired quality of life and strongly reduced life expectancy. The article identifies key activities for the next 5-10 years to address the problem.

 

Approaches for Evaluation of Asymptomatic Microscopic Hematuria

20Apr
2017

Cost-effectiveness of Common Diagnostic Approaches for Evaluation of Asymptomatic Microscopic Hematuria – JAMA Internal Medicine (free)

Invited commentary: Asymptomatic Microscopic Hematuria – Rethinking the Diagnostic Algorithm (free)

Routine urinalysis for screening is not presently recommended by any major health organization, but asymptomatic microscopic hematuria is a common incidental finding. This study suggests that the combination of renal ultrasound and cystoscopy is the most cost-effective approach for the evaluation of these patients.

 

Screening for Endocrine Hypertension

14Apr
2017

Screening for Endocrine Hypertension: An Endocrine Society Scientific Statement (free)

Source: Screen for Endocrine Hypertension, Endocrine Society Says – Medscape (free registration required)

“The statement provides guidance on screening for 15 hormonal disorders that present with hypertension and that can be potentially cured with surgery or treated with medication” (from Medscape commentary above).

 

Achieved blood pressure and cardiovascular outcomes in high-risk patients

11Apr
2017

 

Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials – The Lancet (link to abstract – $ required for full-text) (RT @AnilMakam “Lower achieved blood pressure in high risk patients for cardiovascular disease do WORSE” see Tweets)

In high-risk patients, patients who achieved a systolic blood pressure < 120 mmHg or a diastolic blood pressure < 70 mmHg had HIGHER risk of complications. “These data suggest that the lowest blood pressure possible is not necessarily the optimal target for high-risk patients”

 

Hypertension Canada’s 2017 Guidelines

10Apr
2017

Management of cystic renal lesions

5Apr
2017

American College of Radiology (ACR) Appropriateness Criteria Adds Topics

4Apr
2017

ACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)

Browse Appropriateness Criteria Topics (free)

Source: Newswise

This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.

 

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