2019 Update of the Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA–EDTA) recommendations for the management of lupus nephritis – Annals of Rheumatic Diseases

Commentary: EULAR, ERA–EDTA issue guidelines for managing lupus nephritis – Medicine Matters

Related Guidelines: Consensus of the Brazilian Society of Rheumatology for the diagnosis, management and treatment of lupus nephritis (free) AND 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus (free) AND 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus (free) AND Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology (free) AND The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults (free) AND First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus (free) AND Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus (free PDF)

Related Reviews: Update on Lupus Nephritis – Clinical Journal of the American Society of Nephrology (free) AND Immunosuppressive Treatment for Proliferative Lupus Nephritis – Cochrane Library (free) AND Induction and Maintenance Immunosuppression Treatment of Proliferative Lupus Nephritis: A Network Meta-analysis of Randomized Trials. – American Journal of Kidney Diseases (free)


N95 Re-Use Instructions:


Stanford: N95 masks can be decontaminated without decreasing filtration efficiency using 70C heat for 30 min. Alcohol and bleach should not be used.” (via @CMichaelGibson see Tweet)

“…among patients with COVID-19 infection, clinicians are advised to only measure troponin if the diagnosis of acute MI is being considered on clinical grounds and an abnormal troponin should not be considered evidence for an acute MI without corroborating evidence.”



Practical Advice: PPE Pearls

COVID Ethics: Should clinicians see patients without appropriate PPE?


Selected Articles:

“Coronaviruses have not shown to cause a more severe disease in immunosuppressed patients. For this family of viruses the host innate immune response appears the main driver of lung tissue damage during infection.”

News & Perspectives:

COVID-19 Critical Care: This page will be updated as often as necessary and will be fixed in the right column on our homepage.


COVID-19: Updates for Anesthesiologists

29 Mar, 2020 | 00:10h | UTC



COVID-19 Anesthesiology: This page will be updated as often as necessary and will be fixed in the right column on our homepage.


COVID-19 Updates for Obstetricians

6 Apr, 2020 | 00:22h | UTC





Information for Pregnant Women and Their Families:

COVID-19 Obstetrics: This page will be updated as often as necessary and will be fixed in the right column on our homepage.


Infection Prevention and Control guidance for Long-Term Care Facilities in the context of COVID-19 – World Health Organization (PDF)

Related Study: COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020 – CDC Morbidity and Mortality Weekly Report (free)

“Introduction of COVID-19 into a long-term residential care facility in Washington resulted in cases among 81 residents, 34 staff members, and 14 visitors; 23 persons died” (from CDC)


Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected – World Health Organization (free PDF)

Related: Severe SARS-CoV-2 Infections: Practical Considerations and Management Strategy for Intensivists (free studies and reviews)


Related Commentary on Twitter


Mental Health and Psychosocial Considerations During COVID-19 Outbreak – World Health Organization (free PDF)

Related: The psychological impact of quarantine and how to reduce it: rapid review of the evidence – The Lancet (free) AND Behavioural scientists form new front in battle against coronavirus – The Guardian (free)

“Minimize watching, reading or listening to news that causes you to feel anxious or distressed; seek information only from trusted sources and mainly to take practical steps to prepare your plans and protect yourself and loved ones.”


Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ (free)

See also: Latest Research on the COVID-19 Outbreak (free resources)


Related Commentary on Twitter


8 Things to Know About E-cigarettes

6 Mar, 2020 | 10:25h | UTC

Getting your workplace ready for COVID-19 – World Health Organization (free PDF)

Related Guideline: COVID-19: guidance for employers and businesses – Public Health England (free)

“WHO just published guidance on how to prevent the spread of COVID- 19 in a workplace & protect your customers, contractors & employees. We advise these measures to be taken now, even if coronavirus hasn’t arrived in communities where you operate.” (via @DrTedros see Tweet)


Clinical diagnosis of benign paroxysmal positional vertigo and vestibular neuritis – Canadian Medical Association Journal (free)


Related Commentary on Twitter


On the ethics of algorithmic decision-making in healthcare – Journal of Medical Ethics (free)

Commentary: Experts Raise Ethical Concerns About Machine Learning in Medicine – Mad in America (free)


Related Commentary on Twitter


Review: Hip Pain in Children

21 Feb, 2020 | 08:32h | UTC

Trends and risk factors of mortality and disability adjusted life years for chronic respiratory diseases from 1990 to 2017: systematic analysis for the Global Burden of Disease Study 2017 – The BMJ (free)

Commentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)


Related Commentary on Twitter


Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials – Circulation: Cardiovascular Quality and Outcomes (free)

Editorial: The ISCHEMIA Trial Meets the Rashomon Effect: Lessons for Clinical Practice (free for a limited period)


Related Commentary on Twitter


Challenges and opportunities for cancer clinical trials in low- and middle-income countries – Nature Cancer (free PDF)


Related Commentary on Twitter


Cannabis use during pregnancy and postpartum – Canadian Family Physician (free)

Related: AAP Clinical Report: Implications of Marijuana Use During Pregnancy and Breastfeeding (free report and commentaries)

“There is no known safe level of cannabis use during pregnancy or lactation”


A Clinician’s Guide to Artificial Intelligence: How to Critically Appraise Machine Learning Studies – Translational Vision Science & Technology (free)


Related Commentary on Twitter


Leg ulcer infection: antimicrobial prescribing – National Institute for Health and Care Excellence (free)

Related: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)


Related Commentary on Twitter


Guidelines for the management of glucocorticoids during the peri‐operative period for patients with adrenal insufficiency – Anaesthesia (free)


Related Commentary on Twitter


Recommended Adult Immunization Schedule, United States, 2020 – Annals of Internal Medicine (free)

Commentary: ACIP releases updated vaccination schedule with several changes – ACP Hospitalist (free)


Related Commentary on Twitter


NICE Guideline: Colorectal Cancer

30 Jan, 2020 | 07:38h | UTC