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Internal Medicine

Cohort Study | Comparison of propylthiouracil vs. methimazole for thyroid storm in critically ill patients

4 May, 2023 | 13:47h | UTC

Comparison of Propylthiouracil vs Methimazole for Thyroid Storm in Critically Ill Patients – JAMA Network Open

News Release: Study: No significant differences in mortality, adverse events in patients taking thyroid medications – Boston University

 


Treating long-lasting low back pain without surgery: the latest evidence

4 May, 2023 | 13:40h | UTC

Treating long-lasting low back pain without surgery: the latest evidence – Evidently Cochrane

 


Cohort Study | Risk factors for mortality from aortic aneurysm and dissection

4 May, 2023 | 13:41h | UTC

Risk Factors for Mortality From Aortic Aneurysm and Dissection: Results From a 26‐Year Follow‐Up of a Community‐Based Population – Journal of the American Heart Association

Commentary: Aortic Disease Deaths Tied to Modifiable Risk Factors, Japanese Data Confirm – TCTMD

 


Review | Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension

4 May, 2023 | 13:36h | UTC

Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension – Liver International

 


Review | A practical guide to hidradenitis suppurativa

4 May, 2023 | 13:29h | UTC

A practical guide to hidradenitis suppurativa – Family Practice

 


SR | In people with prediabetes, Vitamin D may have a small benefit in decreasing the risk of diabetes

4 May, 2023 | 13:28h | UTC

Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes: A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries:

Expert reaction to study looking at vitamin D supplementation and reduction in diabetes risk – Science Media Centre

How Helpful Is Vitamin D in Prediabetes? – ConscienHealth

 


RCT | Best endovascular treatment first strategy yields better outcomes for chronic limb ischemia vs. vein bypass first strategy

3 May, 2023 | 15:39h | UTC

A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial – The Lancet

Commentary: BASIL-2 Supports Endo-First Strategy for CLTI With Infrapopliteal Disease – TCTMD

 


M-A | Efficacy of osteoporosis interventions on fracture prevention in postmenopausal women

3 May, 2023 | 15:37h | UTC

Fracture risk reduction and safety by osteoporosis treatment compared with placebo or active comparator in postmenopausal women: systematic review, network meta-analysis, and meta-regression analysis of randomised clinical trials – The BMJ

 


M-A | Direct oral anticoagulants versus warfarin across the spectrum of kidney function in patients with AF

3 May, 2023 | 15:32h | UTC

Direct Oral Anticoagulants Versus Warfarin Across the Spectrum of Kidney Function: Patient-Level Network Meta-Analyses From COMBINE AF – Circulation (free for a limited period)

 

Commentary on Twitter

 


Differential diagnosis, prevention, and treatment of mpox (Monkeypox): a review for dermatologists

3 May, 2023 | 15:27h | UTC

Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

Related: Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

 


SR | Fecal microbiota transplantation effective in recurrent C. difficile treatment

3 May, 2023 | 15:29h | UTC

Fecal microbiota transplantation for the treatment of recurrent Clostridioides difficile (Clostridium difficile) – Cochrane Library

Summary: Stool transplantation for treatment of repeated Clostridioides difficile infection – Cochrane Library

Commentaries:

Cochrane study finds stool transplants more effective than antibiotics for treating recurring, life-threatening gut infections – Cochrane Library

Expert reaction to two Cochrane reviews looking at stool transplants for recurrent Clostridium difficile infection, and for inflammatory bowel disease – Science Media Centre

Fecal microbiota transplant: Effective solution for recurrent C. difficile infections – News Medical

Related:

RCT | Fecal microbiota transplantation better than standard of care for first or second Clostridioides difficile infection.

Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection

 

Commentary on Twitter

 


Supportive care management recommendations for mucocutaneous manifestations of monkeypox infection

3 May, 2023 | 15:26h | UTC

Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

Related: Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

 


Scientific Statement | Iron deficiency in heart failure

3 May, 2023 | 15:25h | UTC

Iron Deficiency in Heart Failure: A Scientific Statement from the Heart Failure Society of America – Journal of Cardiac Failure

 


Clinical practice guidelines on hemochromatosis

3 May, 2023 | 15:23h | UTC

Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver – Hepatology International

 


Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis

3 May, 2023 | 15:22h | UTC

Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis – Gut

 


Review | Calciphylaxis and kidney disease

3 May, 2023 | 15:20h | UTC

Calciphylaxis and Kidney Disease: A Review – American Journal of Kidney Diseases

 


M-A | Long-term major adverse cardiovascular events following myocardial injury after non-cardiac surgery

3 May, 2023 | 15:05h | UTC

Long-term major adverse cardiovascular events following myocardial injury after non-cardiac surgery: meta-analysis – BJS Open

 

Commentary on Twitter

 


RCT | High vs. low target mean arterial pressure in patients with cirrhosis and septic shock

3 May, 2023 | 15:01h | UTC

A randomized-controlled trial (TARGET-C) of high vs. low target mean arterial pressure in patients with cirrhosis and septic shock – Journal of Hepatology

 


Cohort Study | Long-term health consequences after ovarian removal at benign hysterectomy

3 May, 2023 | 14:58h | UTC

Long-Term Health Consequences After Ovarian Removal at Benign Hysterectomy: A Nationwide Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Risks of removing ovaries at benign hysterectomy may outweigh the benefits for women at low risk for ovarian cancer – American College of Physicians

 


Scientific Statement | Role of natriuretic peptides in the diagnosis and management of heart failure

2 May, 2023 | 14:05h | UTC

Natriuretic Peptides: Role in the Diagnosis and Management of Heart Failure: A Scientific Statement From the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society – European Journal of Heart Failure

 


AHA Scientific Statement | Hypertension in patients treated with in-center maintenance hemodialysis

2 May, 2023 | 14:02h | UTC

Hypertension in Patients Treated With In-Center Maintenance Hemodialysis: Current Evidence and Future Opportunities: A Scientific Statement From the American Heart Association – Hypertension

Top Things to Know: HTN in Patients Treated with In-Center Maintenance Hemodialysis: Current Evidence and Future Opportunities – American Heart Association

 

Commentary on Twitter

 


ChatGPT’s responses to patient questions rated higher for quality and empathy than physicians

2 May, 2023 | 14:00h | UTC

ChatGPT’s responses to patient questions rated higher for quality and empathy than physicians

Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum – JAMA Internal Medicine (free for a limited period)

Commentaries:

How Chatbots and Large Language Model Artificial Intelligence Systems Will Reshape Modern Medicine: Fountain of Creativity or Pandora’s Box? – JAMA Internal Medicine (free for a limited period)

Expert reaction to study comparing physician and AI chatbot responses to patient questions – Science Media Centre

 

Commentary on Twitter (thread – click for more)

 


RCT | An herbal-based injection reduced 28-day mortality in patients with sepsis

2 May, 2023 | 13:58h | UTC

Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With SepsisThe EXIT-SEP Randomized Clinical Trial – JAMA Internal Medicine

 

Commentary on Twitter

 


Review | Suicide in young people: screening, risk assessment, and intervention

2 May, 2023 | 13:56h | UTC

Suicide in young people: screening, risk assessment, and intervention – The BMJ

 


RCT | Hypotension-avoidance and hypertension-avoidance strategies resulted in similar outcomes in noncardiac surgery

2 May, 2023 | 13:54h | UTC

Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery: An International Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Hypotensive-avoidance strategies not associated with decrease in postoperative hypotension or adverse outcomes – American College of Physicians

Commentary: Hypotension-Avoidance No Better than Hypertension-Avoidance for Reducing Post-Op Adverse Events – HCP Live

 

Commentary on Twitter

 


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