Internal Medicine

Effectiveness of Combined Behavioral and Drug Therapy for Overactive Bladder Symptoms in Men: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentaries: What Works Best to Help Men With Overactive Bladder? – HealthDay News (free) AND For Overactive Bladder in Men, Start with Behavioral Strategies – NEJM Journal Watch (free)

 

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Review: Management of Hypopituitarism

15 Jan, 2020 | 01:04h | UTC

Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: post-hoc safety analysis of two randomised controlled trials – The Lancet Infectious Diseases (free registration required)

Commentaries: What is the best regimen to treat latent tuberculosis infection? – The Lancet Infectious Diseases (free) AND Four Months of Rifampicin May Be Best Option for Latent TB – Medscape / Reuters (free registration required)

 

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Podcast: GERD and Dyspepsia

6 Jan, 2020 | 23:22h | UTC

Guideline Homepage: ADA 2020 Standards of Medical Care in Diabetes – American Diabetes Association (free supplement)

Commentaries: ADA 2020 Standards of Care Incorporate CVD Risk Stratification, New Medications – Endocrinology Advisor (free) AND ADA releases 2020 standards of medical care in diabetes – University of North Carolina at Chapel Hill School of Medicine (free)

See also: Standards of Medical Care in Diabetes—2020 Abridged for Primary Care Providers – American Diabetes Association (free PDF) AND 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) – Diabetologia (free)

 

See ADA 2020 Guideline topics below:

Introduction: Standards of Medical Care in Diabetes—2020

Summary of Revisions: Standards of Medical Care in Diabetes—2020

  1. Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes2020
  2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2020
  3. Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2020
  4. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2020
  5. Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2020
  6. Glycemic Targets: Standards of Medical Care in Diabetes—2020
  7. Diabetes Technology: Standards of Medical Care in Diabetes—2020
  8. Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2020
  9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2020
  10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2020
  11. Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes−2020
  12. Older Adults: Standards of Medical Care in Diabetes—2020
  13. Children and Adolescents: Standards of Medical Care in Diabetes−2020
  14. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2020
  15. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2020

 

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NICE Guideline: Acute Kidney Injury

5 Jan, 2020 | 14:22h | UTC

Alcohol Abstinence in Drinkers with Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Cutting out alcohol may reduce atrial fibrillation episodes – Reuters (free) AND Atrial Fibrillation and Alcohol Abstinence – MedicalResearch.com (free) AND Alcohol Abstinence Linked to Lower Risk for Atrial Fibrillation Recurrence – NEJM Journal Watch (free)

 

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Effectiveness of management strategies for uninvestigated dyspepsia: systematic review and network meta-analysis – The BMJ (free)

Commentary: Managing Dyspepsia with “Test and Treat” Ranked Best Strategy – NEJM Journal Watch (free)

 

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Homepage: CPR Guidelines (free summaries and infographics)

– 2019 Highlights – Guidelines Update for CPR & ECC

– 2019 FAQ – Guidelines Update for CPR & ECC

– 2019 Infographic – ACLS Guidelines Update

– 2019 Infographic – PALS Guidelines Update

Original Guidelines: AHA Updates on Advanced Cardiovascular Life Support (ACLS) (free) AND AHA Updates in Pediatric Life Support (free)

 

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The Ketogenic Diet: Pros and Cons

9 Dec, 2019 | 01:30h | UTC

NICE Guideline: Menopause

6 Dec, 2019 | 10:50h | UTC

Effect of Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions: A Randomized Clinical Trial – JAMA (free for a limited period)

 

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Ann Robinson’s research reviews, 5 December 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals

 


ASH Guideline: Immune Thrombocytopenia

5 Dec, 2019 | 11:19h | UTC

The effect of remote ischaemic preconditioning on myocardial injury in emergency hip fracture surgery (PIXIE trial): phase II randomised clinical trial – The BMJ (free)

Related Perspective: Remote ischaemic preconditioning: an intervention for anaesthetists? – British Journal of Anaesthesia (free)

 

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Review: Celiac Disease

4 Dec, 2019 | 08:20h | UTC

Management of severe acute pancreatitis – The BMJ (free for a limited period)

Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)

 

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Supplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)

“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)

 

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Podcast: Update in Sleep Medicine

27 Nov, 2019 | 08:08h | UTC

Iron Deficiency Anemia Revisited

26 Nov, 2019 | 07:35h | UTC

Evaluating a digital sepsis alert in a London multisite hospital network: a natural experiment using electronic health record data – Journal of the American Medical Informatics Association (free)

Commentary: Digital monitoring system helps improve hospital care of sepsis patients – OnMedica (free) AND Sepsis digital alert ‘led to faster treatment with antibiotics’ – BBC (free)

 

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A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Treat Stroke to Target Finds Lower Risk of CV Events With Lower LDL-C Levels – American College of Cardiology (free) AND Treat Stroke to Target – Treat Stroke to Target – American College of Cardiology (free) AND Lower Cholesterol Cuts CV Events: Treat Stroke to Target Trial – TCTMD (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

 

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Coronary Microvascular Dysfunction Causing Cardiac Ischemia in Women – JAMA (free for a limited period)

Related: Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries (study, guidelines, and reviews on the subject)

 

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Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Colchicine Cardiovascular Outcomes Trial – COLCOT – American College of Cardiology (free) AND COLCOT Renews Hope for Anti-inflammatory in Secondary Prevention: Colchicine – TCTMD (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

 

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Outcomes at follow-up of negative colonoscopy in average risk population: systematic review and meta-analysis – The BMJ (free)

Related Guidelines: ACP Guideline: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults (free) AND BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy (new guideline suggesting a more selective approach to screening) AND Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society (recent guideline with recommendation to start screening at 45 years, with links to guidelines from other organizations)

“Our findings suggest that 10 year intervals for colonoscopy screening after a negative colonoscopy, as currently recommended, may be adequate”

 


Alex Nowbar’s weekly review, 15 November 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: What Can We Learn From The Apple Heart Study? – Cardiobrief (free)

“…nearly half a million people were required to identify a few hundred people with AF. (It should further be noted that we have no idea whether the patients identified in this group will even benefit from their diagnosis, since they may differ in important ways from AF patients identified by traditional means.)” (from Cardiobrief)

 


Association of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism – JAMA Internal Medicine (free for a limited period)

 

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Development of Risk Prediction Equations for Incident Chronic Kidney Disease – JAMA (free for a limited period)

See Calculator: Risk of Developing Reduced Kidney Function (free tool)

Editorial: Predicting Risk of Kidney Disease: Is Risk-Based Kidney Care on the Horizon? – JAMA (free for a limited period)

Commentaries: New Tool Predicts Five-Year Risk of Chronic Kidney Disease With High Accuracy – Johns Hopkins Bloomberg School of Public Health (free) AND Researchers Develop Tool to Identify Those at Risk of Future CKD – AJMC (free)

#KidneyWk – Just presented at the American Society of Nephrology Kidney Week 2019

 

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Effect of Vitamin D and Omega-3 Fatty Acid Supplementation on Kidney Function in Patients With Type 2 Diabetes: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Vitamin D and Health Outcomes: Then Came the Randomized Clinical Trials – JAMA (free for a limited period)

Commentary: Supplements don’t preserve kidney health in Type 2 diabetes – University of Washington School of Medicine (free)

#KidneyWk – Just presented at the American Society of Nephrology Kidney Week 2019

 

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