Infectious Diseases (all articles) | Page 4 of 296 | Links Medicus Content Curation & Alerts in Medicine

Review | Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation

21 Jun, 2023 | 13:31h | UTC

Antifungal Dosing in Critically Ill Patients on Extracorporeal Membrane Oxygenation – Clinical Pharmacokinetics

M-A | CRP at 5 mg/L cut-off efficient for tuberculosis screening in HIV outpatients

21 Jun, 2023 | 13:30h | UTC

Clinical utility of WHO-recommended screening tools and development and validation of novel clinical prediction models for pulmonary tuberculosis screening among outpatients living with HIV: an individual participant data meta-analysis – European Respiratory Review

Commentary on Twitter

ERR: C-reactive protein at a 5 mg cut-off and two newly developed clinical prediction models from this study show clinical utility for TB screening among outpatient PLHIV, while the WHO-recommended four-symptom screen showed suboptimal clinical utility https://t.co/msm13KXR0Y pic.twitter.com/O0wS1Xv4da

— ERS publications (@ERSpublications) June 11, 2023

The foot in diabetes – a reminder of an ever-present risk

21 Jun, 2023 | 13:10h | UTC

The foot in diabetes – a reminder of an ever-present risk – Clinical Medicine Journal

Opinion | Strategic masking to protect patients from all respiratory viral infections

20 Jun, 2023 | 12:50h | UTC

Strategic Masking to Protect Patients from All Respiratory Viral Infections – New England Journal of Medicine (link to abstract – $ for full-text)

RCT | Continuous vs. intermittent meropenem administration shows similar mortality and drug-resistance in sepsis patients

19 Jun, 2023 | 14:11h | UTC

Continuous vs Intermittent Meropenem Administration in Critically Ill Patients With Sepsis: The MERCY Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Do Prolonged Infusions of β-Lactam Antibiotics Improve Outcomes in Critically Ill Patients With Sepsis? – JAMA (free for a limited period)

See also: Visual Abstract

Commentary: Trial finds no difference between continuous, intermittent meropenem for sepsis patients – CIDRAP

Commentary on Twitter

Continuous administration of meropenem, compared with intermittent administration, does not improve clinically relevant outcomes in critically ill patients with #sepsis. https://t.co/eJ9zdGI4k2 #CCR23 pic.twitter.com/8n2eR9qBPe

— JAMA (@JAMA_current) June 16, 2023

Review | Necessity of antigen testing for Legionella in hospitalized patients with community-acquired pneumonia

19 Jun, 2023 | 13:56h | UTC

Should urine antigen testing for Legionella pneumophila be ordered for all hospitalized patients with community-acquired pneumonia? – Cleveland Clinic Journal of Medicine

Review | Bloodstream infection and gram-negative resistance: the role for newer antibiotics

16 Jun, 2023 | 13:57h | UTC

Bloodstream Infection and Gram-Negative Resistance: The Role for Newer Antibiotics – Antibiotics

Review | Aminoglycosides for the treatment of severe infection due to resistant gram-negative pathogens

16 Jun, 2023 | 13:56h | UTC

Aminoglycosides for the Treatment of Severe Infection Due to Resistant Gram-Negative Pathogens – Antibiotics

Review | Antifungal stewardship interventions in patients with hematologic malignancies

16 Jun, 2023 | 13:47h | UTC

Antifungal Stewardship Interventions in Patients with Hematologic Malignancies

Perspective | Observational studies must be reformed before the next pandemic

15 Jun, 2023 | 15:12h | UTC

Observational studies must be reformed before the next pandemic – Nature Medicine

Review | Contribution of wastewater to antimicrobial resistance

15 Jun, 2023 | 14:49h | UTC

Contribution of wastewater to Antimicrobial Resistance- A Review article – Journal of Global Antimicrobial Resistance

Related studies on surveillance of wastewater:

Use of Wastewater for Mpox Outbreak Surveillance in California – New England Journal of Medicine

Wastewater network infrastructure in public health: Applications and learnings from the COVID-19 pandemic – PLOS Global Public Health

Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.

CDC unveils its latest weapon in Covid-19 detection: wastewater.

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

Cohort Study | 63.1% of uncomplicated appendicitis in children successfully treated non-operatively at 1 year

15 Jun, 2023 | 14:45h | UTC

Outcomes 1 year after non-operative management of uncomplicated appendicitis in children: Children with AppendicitiS during the CoronAvirus panDEmic (CASCADE) study – BJS Open

Commentary on Twitter

1y outcomes of CASCADE examining?treatment for uncomp?itis in kids ➡️overall success: 63.1%, 21.5% req?during hospitalisation, 10.4% recurrence @1y. Overall comp: 7.3%?vs. 1.3% in success Non?treatment. Thoughts?https://t.co/AuIgSKkU6w #SoMe4Surgery #some4peds #emgensurg pic.twitter.com/9mM5NFOEh1

— BJS Open (@BjsOpen) June 7, 2023

Review | Fluid therapy for critically ill adults with sepsis

14 Jun, 2023 | 14:51h | UTC

Fluid Therapy for Critically Ill Adults With Sepsis: A Review – JAMA (free for a limited period)

Audio clinical review: Fluid Therapy for Critically Ill Adults With Sepsis – JAMA

M-A | Preoperative IV plus oral antibiotics reduce surgical site infections in elective colorectal surgery

14 Jun, 2023 | 14:31h | UTC

Mechanical bowel preparation and antibiotics in elective colorectal surgery: network meta-analysis – BJS Open

M-A: Strategies for antibiotic administration for bowel preparation among patients undergoing elective colorectal surgery – “the addition of oral antibiotics to intravenous antibiotics was associated with a reduction in the incidence of incisional surgical site infection by more than 50%”.

Meta-Analysis: Effects of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery

Commentary on Twitter

Recent network? #metaanalysis indicates that bowel prep w iv + oral antibiotics w/wo mech bowel prep results in ⤵️SSI? and anast insuff☔️ compared to other combinations in colorect?! https://t.co/pALtvscZCh #colorectalsurgery #StepUp4CRC #SoMe4Surgery @Mcfark @LauraLorenzonMD pic.twitter.com/KQSBk0NwEB

— BJS Open (@BjsOpen) June 5, 2023

M-A | Oseltamivir fails to lower hospitalization risk in adult and adolescent influenza patients

13 Jun, 2023 | 14:12h | UTC

Evaluation of Oseltamivir Used to Prevent Hospitalization in Outpatients With Influenza: A Systematic Review and Meta-analysis – JAMA Internal Medicine

Commentary on Twitter

In this systematic review and meta-analysis of 15 RCTs, oseltamivir was not associated with reduced risk of first hospitalization compared with placebo or standard of care among influenza-infected adult and adolescent outpatients. https://t.co/UEqsbA2JQZ

— JAMA Internal Medicine (@JAMAInternalMed) June 12, 2023

Review | Wastewater monitoring can anchor global disease surveillance systems

13 Jun, 2023 | 14:07h | UTC

Wastewater monitoring can anchor global disease surveillance systems – The Lancet Global Health

Wastewater network infrastructure in public health: Applications and learnings from the COVID-19 pandemic – PLOS Global Public Health

Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.

CDC unveils its latest weapon in Covid-19 detection: wastewater.

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

Review | Challenges and opportunities in antimicrobial stewardship among hematopoietic stem cell transplant and oncology patients

13 Jun, 2023 | 13:55h | UTC

Challenges and Opportunities in Antimicrobial Stewardship among Hematopoietic Stem Cell Transplant and Oncology Patients – Antibiotics

IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections

12 Jun, 2023 | 13:58h | UTC

IDSA 2023 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections – Infectious Diseases Society of America

A position paper for the diagnosis and management of infections caused by multidrug-resistant bacteria: Endorsed by the Italian Society of Infection and Tropical Diseases (SIMIT), the Italian Society of Anti-Infective Therapy (SITA), the Italian Group for Antimicrobial Stewardship (GISA), the Italian Association of Clinical Microbiologists (AMCLI), and the Italian Society of Microbiology (SIM) – International Journal of Antimicrobial Agents

The threat of multidrug-resistant/extensively drug-resistant Gram-negative respiratory infections: another pandemic – European Respiratory Review

2ry Analysis of a RCT | Metformin linked to 41% reduction in long COVID incidence in outpatient treatment

12 Jun, 2023 | 13:55h | UTC

Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial – The Lancet Infectious Diseases

News Release: Study shows metformin lowers the risk of getting long COVID – University of Minnesota Medical School

Commentary: Expert reaction to study on Metformin after testing positive for SARS-CoV-2 and risk of developing long COVID – Science Media Centre

Commentary on Twitter

These data not persuasive. There are 6 different arms. 3 drugs. This is not the primary endpoint. No adjustment for multiple testing.

Even USFDA would not accept these data for regulatory approval, and they are basically working for Pharma at this pthttps://t.co/FZoxo9shtG

— Vinay Prasad MD MPH (@VPrasadMDMPH) June 9, 2023