Infectious Diseases (all articles)
Perspective | Why BA.5 feels different: the latest wave of infections is a test of our pandemic priorities.
12 Jul, 2022 | 13:03h | UTCWhy BA.5 Feels Different – The Atlantic
M-A | Global changes in child and adolescent physical activity during the COVID-19 pandemic.
12 Jul, 2022 | 12:53h | UTCGlobal Changes in Child and Adolescent Physical Activity During the COVID-19 Pandemic: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
M-A | Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2.
12 Jul, 2022 | 12:50h | UTCRelated:
Interpreting a lateral flow SARS-CoV-2 antigen test – The BMJ
Network M-A | Effects of therapies for Ebola virus disease.
12 Jul, 2022 | 11:45h | UTC
Ghana reports first-ever suspected cases of Marburg virus disease.
11 Jul, 2022 | 12:44h | UTCGhana reports first-ever suspected cases of Marburg virus disease – World Health Organization
Commentary on Twitter
Ghana has announced the preliminary finding of two cases of #Marburg virus disease and if confirmed these would the first such infections recorded in the country
➡️ https://t.co/GrjuK7itmw pic.twitter.com/SiariKqRI3— WHO African Region (@WHOAFRO) July 7, 2022
Systematic Review | Ethical values and principles to guide the fair allocation of resources in response to a pandemic.
11 Jul, 2022 | 12:42h | UTC
European Medicines Agency recommends second COVID booster for people over 60 – as WHO ponders guidance.
11 Jul, 2022 | 12:41h | UTC
How contagious is monkeypox — and should you get a vaccine? Here’s the latest.
11 Jul, 2022 | 12:31h | UTCHow contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic
Related:
Prevention and Treatment of Monkeypox – Drugs
Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP
No room for complacency – World Health Organization
Multi-country monkeypox outbreak: situation update – World Health Organization
Monkeypox Genital Lesions – New England Journal of Medicine
Monkeypox vaccination begins — can the global outbreaks be contained? – Nature
Incubation period for monkeypox: Estimates from the Netherlands.
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
Rename monkeypox strains to remove geographic stigma, researchers say – Science
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
RCT | 20% albumin vs. plasmalyte in patients with cirrhosis and sepsis-induced hypotension.
11 Jul, 2022 | 12:16h | UTC
RCT | Neutralizing COVID-19 convalescent plasma does not benefit adults hospitalized with COVID-19.
8 Jul, 2022 | 11:59h | UTC
Interim Analysis | Oral Sabizabulin for high-risk, hospitalized adults with Covid-19.
8 Jul, 2022 | 12:02h | UTCOral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence
M-A | The efficacy and tolerability of antibiotics in scrub typhus.
8 Jul, 2022 | 11:32h | UTC
M-A | Prenatal antibiotic exposure, asthma, and the atopic march.
8 Jul, 2022 | 11:31h | UTC
Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.
7 Jul, 2022 | 13:00h | UTC
Retrospective Cohort Study | Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients.
7 Jul, 2022 | 12:57h | UTCNews Release: Pulse oximeters missed low oxygen levels in more Black veterans than white veterans – University of Michigan
Related:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Commentary on Twitter
New research found that for individuals in general (medical and surgical) care in hospital, occult hypoxemia was more common for black patients than for white patients https://t.co/DrNlaIE7ho
— The BMJ (@bmj_latest) July 6, 2022
M-A | It is not safe to withhold antibiotic use in uncomplicated urinary tract infections in adult women.
7 Jul, 2022 | 12:47h | UTC
Commentary on Twitter (thread – click for more)
A really important analysis of previous trials!
1/ All short-term outcomes were worse for women given non-antibiotic strategies, including need for future antibiotics (number needed to harm=5!) https://t.co/iozelljFLk
— Annie Joseph (@ajosephnotts) July 2, 2022
Review | Tuberculosis in cirrhosis – A diagnostic and management conundrum.
7 Jul, 2022 | 12:18h | UTC
M-A | Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrheal disease in children in low-income and middle-income settings.
6 Jul, 2022 | 11:56h | UTC
Commentary on Twitter
WASH meta-analysis in @TheLancet
Effectiveness of WASH interventions on child diarrhoea in LMICshttps://t.co/yVtoyattQd
How effective are
– water supply (by level of service)
– POU water treatment (by type)
– sanitation (by LoS)
– handwashing with soapRead to find out!
— Environmental Health Group, LSHTM (@LSHTM_EHG) July 1, 2022
RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.
6 Jul, 2022 | 11:51h | UTC
Commentary on Twitter
In this RCT, high-dose dexamethasone did not significantly improve the 60-day survival. The oxygenation strategy in initially non-intubated patients did not significantly modify the 28-day risk of invasive mechanical ventilation requirement. https://t.co/ZNajW2KBKR
— JAMA Internal Medicine (@JAMAInternalMed) July 5, 2022
Review | The vaccine-hesitant moment.
6 Jul, 2022 | 11:49h | UTCThe Vaccine-Hesitant Moment – New England Journal of Medicine
Age and sex-specific risks of myocarditis and pericarditis following Covid-19 messenger RNA vaccines.
6 Jul, 2022 | 11:48h | UTCRCT | Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis.
6 Jul, 2022 | 11:31h | UTCCommentary: Does Azithromycin antagonize the effect of inhaled tobramycin in cystic fibrosis? – Medical Dialogues
Commentary on Twitter
Original research: Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trialhttps://t.co/z9dGX52dAe pic.twitter.com/tpiOqIIQjb
— ThoraxBMJ (@ThoraxBMJ) May 23, 2022
WHO Guideline for the treatment of visceral leishmaniasis in HIV co-infected patients in East Africa and South-East Asia.
5 Jul, 2022 | 12:22h | UTCWHO Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV.
5 Jul, 2022 | 12:23h | UTCIndeterminate pediatric acute liver failure: clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022.
5 Jul, 2022 | 12:09h | UTCRelated:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press