Infectious Diseases (all articles) | Page 2 of 296 | Links Medicus Content Curation & Alerts in Medicine

New WHO guidance on the role of HIV viral suppression in improving individual health and reducing transmission

24 Jul, 2023 | 13:17h | UTC

News Release: New WHO guidance on HIV viral suppression and scientific updates released at IAS 2023 – World Health Organization

WHO Guidance: The role of HIV viral suppression in improving individual health and reducing transmission – Word Health Organization

Related WHO Guidelines:

WHO recommends optimizing HIV testing services – World Health Organization

Primary health care and HIV: convergent actions – World Health Organization

Systematic Review | Low-level HIV viremia (below 1000 copies/mL) linked to minimal sexual transmission risk

24 Jul, 2023 | 13:15h | UTC

The risk of sexual transmission of HIV in individuals with low-level HIV viraemia – The Lancet

Editorial: HIV is sexually untransmittable when viral load is undetectable – The Lancet

Commentary on Twitter

People on ART with low but detectible levels of HIV viral load have almost zero risk of sexually transmitting the virus to others, in-depth review suggests #IAS2023 https://t.co/wU26C8cEMK pic.twitter.com/hQHLDqPxO6

— The Lancet (@TheLancet) July 22, 2023

Cohort Study | Increased risk of depression and suicide among people with HIV, especially in the first two years post-diagnosis

24 Jul, 2023 | 13:01h | UTC

Risk of Depression in People With HIV: A nationwide population-based matched cohort study – Clinical Infectious Diseases

Commentary on Twitter

Risk of Depression in People With HIV: A nationwide population-based matched cohort study

✅ Just Accepted
? Freely Availablehttps://t.co/nyrzPqRRqw

— Clinical Infectious Diseases (@CIDJournal) July 22, 2023

RCT | Long-term Doxycycline for COPD does not reduce exacerbations, except possibly in severe cases or with low eosinophils

24 Jul, 2023 | 12:50h | UTC

A Double-Blind, Randomised, Placebo-controlled Trial of Long-Term Doxycycline Therapy on Exacerbation Rate in Patients with Stable COPD – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)

M-A | Exposure to smoke, overcrowding, poor living conditions, and contact with TB cases identified as risk conditions for pediatric TB

24 Jul, 2023 | 12:43h | UTC

Risk factors for the development of tuberculosis among the pediatric population: a systematic review and meta-analysis – European Journal of Pediatrics

Correspondence | Potential “healthy vaccinee bias” in a study of BNT162b2 vaccine against Covid-19

21 Jul, 2023 | 13:43h | UTC

Potential “Healthy Vaccinee Bias” in a Study of BNT162b2 Vaccine against Covid-19 – New England Journal of Medicine

Commentary from the author on Twitter (thread – click for more)

Our correspondence is out in @njem written w @VPrasadMDMPH & Ram Duriseti

We show v strong evidence of healthy vaccinee bias in an Israeli study of Pfizer booster vs covid death, which wasn't disclosed

Could explain ALL reported benefit of the booster?https://t.co/F3WeafvUnw pic.twitter.com/b29YQ0lblh

— Tracy Høeg, MD, PhD (@TracyBethHoeg) July 20, 2023

Phase 2 Trial | Maternal GBS6 vaccine shows promise in infant group B strep prevention

21 Jul, 2023 | 13:34h | UTC

Potential for Maternally Administered Vaccine for Infant Group B Streptococcus – New England Journal of Medicine

Commentary: Maternal strep B vaccine slashes risk of infection among infants – CIDRAP

RCT | Molecular screening for bacterial vaginosis does not significantly reduce preterm birth rates

21 Jul, 2023 | 13:31h | UTC

Effectiveness and Costs of Molecular Screening and Treatment for Bacterial Vaginosis to Prevent Preterm Birth: The AuTop Randomized Clinical Trial – JAMA Pediatrics

See also: Visual Abstract

IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections

20 Jul, 2023 | 11:15h | UTC

Infectious Diseases Society of America 2023 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections – Clinical Infectious Diseases

RCT | Direct oral challenge noninferior to skin testing followed by direct oral challenge in low-risk penicillin allergy patients

18 Jul, 2023 | 13:54h | UTC

Efficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

See also: Visual Abstract

News Release: World-first clinical trial to help millions with penicillin allergies – Vanderbilt University Medical Center

Commentary: Trial supports use of direct oral challenge for penicillin allergy – CIDRAP

Cohort study | Poor sensitivity of procalcitonin-on-admission for ruling out bloodstream infections in patients with suspected sepsis

18 Jul, 2023 | 13:39h | UTC

Reliability of Admission Procalcitonin Testing for Capturing Bacteremia Across the Sepsis Spectrum: Real-World Utilization and Performance Characteristics, 65 U.S. Hospitals, 2008–2017 – Critical Care Medicine (link to abstract – $ for full-text)

Review | Infection prevention and control in the medical imaging environment

18 Jul, 2023 | 13:31h | UTC

Infection prevention and control in the medical imaging environment: a scoping review – Insights into Imaging

Guideline | Antibiotic therapy in patients with suspected antibiotic allergy

17 Jul, 2023 | 13:59h | UTC

The Dutch Working Party on Antibiotic Policy (SWAB) guideline for the approach to suspected antibiotic allergy – Clinical Microbiology and Infection

Systematic Review | Criteria to achieve safe antimicrobial intravenous-to-oral switch in hospitalized adult populations

17 Jul, 2023 | 13:34h | UTC

Criteria to achieve safe antimicrobial intravenous-to-oral switch in hospitalised adult populations: a systematic rapid review – BMJ Open

Case Series | Cutibacterium acnes endocarditis often misdiagnosed due to absence of typical symptoms and delayed culture results

17 Jul, 2023 | 13:31h | UTC

Clinical Characteristics and Outcomes of Patients With Cutibacterium acnes Endocarditis – JAMA Network Open

Cohort Study | Long-acting antiretroviral therapy may achieve virologic suppression in HIV patients with adherence challenges

17 Jul, 2023 | 13:26h | UTC

Demonstration Project of Long-Acting Antiretroviral Therapy in a Diverse Population of People With HIV – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Long-Acting ART Achieves Virologic Suppression for People With HIV – HealthDay

Consensus Paper | Implementing strategies to prevent infections in acute-care settings

14 Jul, 2023 | 13:03h | UTC

Implementing strategies to prevent infections in acute-care settings – Infection Control & Hospital Epidemiology

News Release: New guidance for infection prevention in acute care settings – Society for Healthcare Epidemiology of America

Consensus Paper | Strategies to prevent surgical site infections in acute-care hospitals

Consensus Paper | Strategies to prevent Clostridioides difficile infections in acute-care hospitals

SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update – Infection Control & Hospital Epidemiology

SHEA statement on antibiotic stewardship in hospitals during public health emergencies – Infection Control & Hospital Epidemiology

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

Quality Improvement Study | Improved asymptomatic bacteriuria management by reduction of unnecessary urine culture requests

14 Jul, 2023 | 12:54h | UTC

A Statewide Quality Initiative to Reduce Unnecessary Antibiotic Treatment of Asymptomatic Bacteriuria – JAMA Internal Medicine

Study: Hospital Intervention Resulted in a 45% Reduction in the Urine Cultures Ordered

Optimal Urine Culture Diagnostic Stewardship Practice—Results from an Expert Modified-Delphi Procedure – Clinical Infectious Diseases

USPSTF Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults

Cohort Study: Antibiotic Treatment of Asymptomatic Bacteriuria in Hospitalized Patients is Common, and May be Associated with Longer Duration of Hospitalization

Inappropriate Management of Asymptomatic Patients With Positive Urine Cultures: A Systematic Review and Meta-analysis – Open Forum Infectious Diseases

IDSA Guideline for the Management of Asymptomatic Bacteriuria

Commentary on Twitter

???Powerful message from our new study in @JAMAInternalMed: diagnostic stewardship (better use of diagnostic tests) was responsible for ALL the⬇️in unnecessary antibiotic use for ASB. ➕results??nudge to action. Time to??upstream to improve care! https://t.co/yO4UpA6ZKK pic.twitter.com/hXZGvNmVJP

— Valerie Vaughn (@ValerieVaughnMD) July 11, 2023

Retrospective Analysis | 18% of ICU patients develop sepsis-associated AKI, mostly stage 1, diagnosed by low urine output

12 Jul, 2023 | 13:39h | UTC

Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study – Intensive Care Medicine

Commentary on Twitter

Fulminant myocarditis in #ICU
?short/long‑term prognosis
?clinical suspicion, initial recognition, differential diagnoses
?initial management & temporary #MCS: IABP #ECMO #Impella
?endomyocardial biopsy
?immunomodulatory therapies
?#FOAMcc @yourICM
?️https://t.co/JIGm4p0tv5 pic.twitter.com/o4RctuurEL

— Intensive Care Medicine (@yourICM) July 11, 2023