Infectious Diseases

The Ongoing Ebola Epidemic in the Democratic Republic of Congo, 2018–2019 – New England Journal of Medicine (free)


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Predictors of mortality in patients with yellow fever: an observational cohort study – The Lancet Infectious Diseases (link to abstract – $ for full-text)

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Review: Hand Infections

20 May, 2019 | 15:24h | UTC

Fighting Ebola When Mourners Fight the Responders – The New York Times (10 articles per month are free)

Related: DRC Ebola cases top 1,800 amid burial team attacks – CIDRAP (free)

“An Ebola outbreak in eastern Congo — the second-largest in history — is escalating in part because locals don’t trust health workers and government officials.”


Management of Hepatitis C in 2019 – JAMA (free for a limited period)


Normal Body Temperature: A Systematic Review – Open Forum Infectious Diseases (free)

See also: Interest “Tweetorial” about the definition of a fever (thread)

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Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017 – Nature (free)

Commentaries: ‘Striking’ differences in rates of HIV/AIDS within African nations – Institute for Health Metrics and Evaluation (free) AND New HIV Map Offers Most Detailed Look Yet At The Epidemic – NPR (free)


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Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial – The Lancet (free)

Invited Commentary: Antibiotics for operative vaginal delivery: practice-changing data – The Lancet (free)


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Report: Access Barriers to Antibiotics

10 May, 2019 | 04:51h | UTC

Implementation manual to prevent and control the spread of carbapenem-resistant organisms at the national and health care facility level – World Health Organization (free PDF manual and resources)

Related Systematic Review: Control of Carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa in Healthcare Facilities – Clinical Infectious Diseases (free)

See also: Prevention and Treatment of Surgical Site Infections (free guidelines on the subject)


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WHO World Immunization Week

26 Apr, 2019 | 02:12h | UTC

World Immunization Week, 24 – 30 April 2019 – World Health Organization (free resources)

See also: #vaccineswork (free text and infographics)


Optimal management after paediatric lumbar puncture: a randomized controlled trial – BMC Neurology (free)

Related Cochrane Review : Posture and fluids for preventing post‐dural puncture headache (free) AND Summary: Body position and intake of fluids for preventing headache after a lumbar puncture (free)

After a lumbar puncture in children, a shorter time (30 min) of fasting and lying supine without a pillow is not associated with a higher risk of post-lumbar puncture headache or lower back pain.


WHO: Malaria Vaccine Pilot Launched

25 Apr, 2019 | 06:35h | UTC

Review: Clostridium Difficile Infection

21 Apr, 2019 | 21:16h | UTC

Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study – The Lancet (free)

Commentaries: Population versus individual protection by pneumococcal conjugate vaccination – The Lancet (free) AND PCV10 pneumococcal vaccine has big impact in Kenya, even among unvaccinated individuals – Johns Hopkins University Bloomberg School of Public Health (free)


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Measles cases are up nearly 300% from last year. This is a global crisis – CNN (free)

WHO Statement: New measles surveillance data for 2019 – World Health Organization (free)

By Henrietta H Fore (executive director of UNICEF) and Tedros Adhanom Ghebreyesus (director general of the World Health Organization).


A Mysterious Infection, Spanning the Globe in a Climate of Secrecy – The New York Times (10 articles per month are free)

Related: CDC Guideline: Candida auris (free) AND A ‘perfect storm’ superbug: How an invasive fungus got health officials’ attention (free) AND Review: Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally (free) AND Epidemiology, Clinical Characteristics, Resistance, and Treatment of Infections by Candida Auris (free)

“The rise of Candida auris embodies a serious and growing public health threat: drug-resistant germs.”


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Global expansion and redistribution of Aedes-borne virus transmission risk with climate change – PLOS Neglected Tropical Diseases (free)

Commentaries: CHART: Where Disease-Carrying Mosquitoes Will Go In The Future – NPR (free) AND Mosquito-spread diseases may endanger millions in new places due to climate change – The Guardian (free)

Related: Climate Change — A Health Emergency (free reports and commentaries on the subject)


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World Tuberculosis Day | 24 March 2019

24 Mar, 2019 | 12:59h | UTC

Opting Out of Vaccines Should Opt You Out of American Society – Scientific American (free)

Although you have a right to your own body, your choice to willfully be sick ends where another’s right to be healthy begins.”


Guidelines for Antibiotic Prescription in Intensive Care Unit – Indian Journal of Critical Care Medicine (free PDF)

Source: Critical Care Reviews Newsletter

Comprehensive guideline covering many common conditions in the Critical Care Unit.


One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis – New England Journal of Medicine (free for a limited period)

Editorial: Ending Tuberculosis through Prevention (free)

Commentary: Ultrashort TB Therapy Found Just As Effective as 6 Month Course – (free)


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A Randomized Trial of Prophylactic Antibiotics for Miscarriage Surgery – New England Journal of Medicine (free for a limited period)

Video Summary: Prophylactic Antibiotics before Miscarriage Surgery (free)

Commentaries: Research shines light on preventing infection after miscarriage – University of Birmingham (free) AND Antibiotics before miscarriage surgery not tied to fewer infections – CIDRAP (free)


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Signs and Symptoms That Rule out Community-Acquired Pneumonia in Outpatient Adults: A Systematic Review and Meta-Analysis – Journal of the American Board of Family Medicine (free)

Adults with an acute respiratory infection who have normal vital signs (temperature < 37,8 / respiratory rate < 20 / heart rate < 100) and a normal pulmonary examination are very unlikely to have CAP.


Ebola virus disease – The Lancet (free for a limited period)



Perspective: Why Are Mothers Still Passing Syphilis to Their Babies? – JAMA (free for a limited period)

Related: A Rising Threat to Pregnant Women: Syphilis – The New York Times (10 articles per month are free)


A practical guide for pharmacists to successfully implement penicillin allergy skin testing – American Journal of Health-System Pharmacy (free)

“Less than 10% of patients labeled as having a penicillin allergy are confirmed as present upon skin testing. This labeling results in use of alternative antibiotics and thus unwanted adverse consequences including potentiated antimicrobial resistance, increased costs, and worse clinical outcomes.”


2019 ACIP Adult Immunization Schedule

5 Feb, 2019 | 00:39h | UTC

International Consensus Guidelines for the Optimal Use of the Polymyxins – Pharmacotherapy (free)

Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).


Oral versus Intravenous Antibiotics for Bone and Joint Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Related Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis (link to abstract and commentaries)

Commentary: Oral antibiotics may work for some ortho, heart infections – CIDRAP (free)


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