Hematology

NCCN Guideline: Systemic Mastocytosis

9 Jan, 2019 | 08:48h | UTC

Transfusion of red blood cells stored for shorter versus longer duration for all conditions – Cochrane Library (free)

Summary: Transfusion of red blood cells stored for a shorter duration versus red blood cells stored for a longer duration for all conditions – Cochrane Library (free)

 

 


Review: Cancer-Associated Thrombosis

5 Nov, 2018 | 11:51h | UTC

NICE Guideline: Multiple Myeloma

2 Nov, 2018 | 02:33h | UTC

Intravenous Iron in Patients Undergoing Maintenance Hemodialysis – New England Journal of Medicine (free)

“Proactive administration of high-dose iv iron did not adversely affect mortality or CV events, but enabled reduced erythropoiesis-stimulating agent dosing and transfusion rates.” (via @NatRevNeph see Tweet)

 


Review: Cancer-Associated Thrombosis

16 Oct, 2018 | 21:45h | UTC

Review: Rare Thrombophilic Conditions

16 Oct, 2018 | 21:34h | UTC

Guideline: Immune Thrombocytopenia

27 Sep, 2018 | 22:25h | UTC

Guideline: Hodgkin Lymphoma in Adults

2 Sep, 2018 | 02:03h | UTC

Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery – New England Journal of Medicine (free for a limited period)

“In moderate-to-high-risk patients undergoing cardiac surgery, six-month outcomes show that a restrictive red-cell transfusion strategy is noninferior to a liberal strategy” (via @NEJM see Tweet with Visual Abstract)

 


Guideline: Pediatric CAR T-Cell Therapy

16 Aug, 2018 | 23:16h | UTC

ESMO Guideline: Hodgkin lymphoma

1 Jun, 2018 | 03:12h | UTC

Global Burden of Multiple Myeloma: A Systematic Analysis for the Global Burden of Disease Study 2016 – JAMA Oncology (free)

“Global incident cases of multiple myeloma more than doubled from 1990-2016 w/incident cases increasing by 126%. The largest increase was in middle-SDI countries, particularly E. Asia with a 262% increase in incidence cases”. (via @IHME_UW see Tweet)

 


Review: Chronic Lymphocytic Leukemia

9 May, 2018 | 16:15h | UTC

Antifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)

“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)

 


Guideline: Iron Deficient Anemia

12 Apr, 2018 | 02:14h | UTC

Clinical Practice Guideline: Iron Deficient Anemia – Toward Optimized Practice (TOP) (free PDF)

See also: Summary (free PDF)

Related: see all TOP Clinical Practice Guidelines, a practical resource for Family Physicians at the point of care.

 


NCCN Guideline: Hodgkin Lymphoma

16 Mar, 2018 | 01:35h | UTC

NCCN Guideline: T-Cell Lymphomas

8 Mar, 2018 | 20:30h | UTC

Review: Mature Lymphoid Malignancies

10 Jan, 2018 | 00:07h | UTC

Early Recurrence and Major Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Treated With Non–Vitamin‐K Oral Anticoagulants (RAF‐NOACs) Study – Journal of the American Heart Association (free)

“Composite rates of recurrence and major bleeding were 12.4% in patients who initiated NOACs within 2 days after acute stroke, 2.1% in those who initiated NOACs between 3 and 14 days, and 9.1% in patients who initiated NOACs >14 days after acute stroke. Future randomized studies to assess timing of initiation and choice of agent in patients with acute stroke and AF are warranted”.

 


Guideline: Myeloid Growth Factors

26 Dec, 2017 | 19:49h | UTC

Guideline: Hairy Cell Leukemia

14 Nov, 2017 | 20:20h | UTC

Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years – JAMA Internal Medicine (free)

“In this population-based cohort study of 1.256.725 persons, there was a significantly lower age- and sex-adjusted incidence rate ratio of cancer among warfarin users vs nonusers”.

 


Pregnancy, thrombophilia, and the risk of a first venous thrombosis: systematic review and bayesian meta-analysis – The BMJ (free)

“Women with antithrombin, protein C, or protein S deficiency or with homozygous factor V Leiden should be considered for antepartum or postpartum thrombosis prophylaxis, or both”.

 


Guideline: Acute Lymphoblastic Leukemia

27 Sep, 2017 | 14:22h | UTC

Review: Sickle Cell Disease

24 Sep, 2017 | 00:15h | UTC

Review: Multiple Myeloma Emergencies

20 Sep, 2017 | 21:06h | UTC