Guideline: Newly diagnosed and relapsed mantle cell lymphoma

22Aug
2017

Guideline: Chronic myeloid leukemia

22Aug
2017

Study: Risk of Arterial Thromboembolism in Patients With Cancer

22Aug
2017

Guideline: Treatment of older patients with acute myeloid leukemia

22Aug
2017

Guideline: treatment of mycosis fungoides/Sézary syndrome

22Aug
2017

Review: Sports participation recommendations for patients with bleeding disorders

22Aug
2017

Standard of Care in Critically Ill Adult Patients With Atypical Hemolytic Uremic Syndrome

17Aug
2017

The effects of physical activity and fatigue on cognitive performance in breast cancer survivors

14Aug
2017

Long-term follow-up of patients with pulmonary thromboembolism

7Aug
2017

Bronchoscopy and bleeding risk

5Aug
2017

Late effects of blood and marrow transplantation

3Aug
2017

Is immunotherapy here to stay in multiple myeloma?

1Aug
2017

Progress in the Diagnosis of Invasive Fungal Disease in Children

1Aug
2017

Diagnostic approaches for inherited hemolytic anemia in the genetic era

1Aug
2017

Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants

25Jul
2017

Effects of NOACs Versus Warfarin in Patients With AF and Valvular Heart Disease

24Jul
2017

Prophylactic Early Erythropoietin for Neuroprotection in Preterm Infants

23Jul
2017

Commentary and perspectives on graft-versus-host disease

23Jul
2017

Emicizumab Prophylaxis in Hemophilia A with Inhibitors

23Jul
2017

Reviews on thrombosis and hemostasis

23Jul
2017

Dose-Reduced Versus Standard Conditioning Followed by Allogeneic Stem-Cell Transplantation for Patients With Myelodysplastic Syndrome

23Jul
2017

Review: How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy

22Jul
2017

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update

22Jul
2017

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update. Comparative Effectiveness Review – Agency for Healthcare Research and Quality (free report and summary)

See also: Executive summary (free PDF)

Source: ACP Journal Wise ($ resource to find articles of interest)

Comprehensive review on the evidence regarding thromboembolism prophylaxis in major orthopedic surgery.

 

Current indication for hematopoietic cell transplantation in adults

21Jul
2017

Living with hematologic cancer: Recommendations, solutions

21Jul
2017

Review: Optimizing diagnostic testing for venous thromboembolism

21Jul
2017

Complications of hematopoietic stem cell transplantation: Bacterial infections

21Jul
2017

Establishing an autologous versus allogeneic hematopoietic cell transplant program in nations with emerging economies

21Jul
2017

Flow cytometry-based diagnosis of primary immunodeficiency diseases

21Jul
2017

New European Society of Medical Oncology (ESMO) Updated Clinical Practice Guidelines

20Jul
2017

Guidelines for diagnosis, prevention and management of central nervous system involvement in diffuse large B-cell lymphoma

18Jul
2017

Iron substitution in the treatment of chronic heart failure

18Jul
2017

Current treatment approaches for NK/T-cell lymphoma

18Jul
2017

Acute Myeloid Leukemia – NCCN Clinical Practice Guidelines

13Jul
2017

NCCN Guidelines Insights: Antiemesis

13Jul
2017

Idarucizumab for Dabigatran Reversal – Full Cohort Analysis

11Jul
2017

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

11Jul
2017

Direct oral anticoagulants for treatment of Heparin-induced Thrombocytopenia

9Jul
2017

Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review – Blood (link to abstract – $ for full-text)

Source: Direct Oral Anticoagulants for Heparin-Induced Thrombocytopenia – Journal Watch ($)

This literature review and observational study suggest direct oral anticoagulants (rivaroxaban, apixaban, dabigatran) are safe and effective for the treatment of Heparin-induced Thrombocytopenia.

 

Guidelines for the use of imaging in the management of myeloma

7Jul
2017

Benefits and Risks of Antithrombotic Therapy in Essential Thrombocythemia

7Jul
2017

Emerging therapies for acute myeloid leukemia

7Jul
2017

Peri-operative blood management

7Jul
2017

Graft-versus-Leukemia Effect Following Hematopoietic Stem Cell Transplantation for Leukemia

7Jul
2017

Hematopoietic cell transplantation for acute lymphoblastic leukemia in adult patients

3Jul
2017

Hematopoietic stem cell transplantation for sickle cell anemia

3Jul
2017

Reduced-intensity versus myeloablative allogeneic transplantation

3Jul
2017

Emerging concepts in cytomegalovirus infection following hematopoietic stem cell transplantation

3Jul
2017

Long-term complications after hematopoietic cell transplantation

3Jul
2017

Direct oral anticoagulants in patients with chronic kidney disease

3Jul
2017

A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery

26Jun
2017

A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts (free resource to find articles of interest)

“Antiplatelet therapy at the time of noncardiac surgery confers minimal bleeding risk with no difference in thrombotic complications. In many cases, it is safe to continue antiplatelet therapy in patients with important indications for their use”

 

Nucleated RBCs may be a predictor of post-discharge mortality and unplanned hospital readmission

21Jun
2017

Nucleated red blood cells, critical illness survivors and postdischarge outcomes: a cohort study – Critical Care (free)

“Presence of nucleated RBCs is a robust predictor of post-discharge mortality and unplanned hospital readmission” (RT @Crit_Care see Tweet)

 

Antiplatelet Therapy in Patients With Coronary Stents Undergoing Elective Noncardiac Surgery

20Jun
2017

New Insight Into the Biology, Risk Stratification, and Targeted Treatment of Myelodysplastic Syndromes

16Jun
2017

Chronic Myeloid Leukemia: What Every Practitioner Needs to Know in 2017

16Jun
2017

World Blood Donor Day (June 14, 2017)

15Jun
2017

Non–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction

15Jun
2017

Non–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentary: NOAC Doses: Just Stick to the Label – MedPage Today (free registration required)

“Among the 1,473 patients with a renal indication for dose reduction, 43.0% were potentially overdosed, which was associated with a higher risk of major bleeding”

 

Low-Dose Ferrous Sulfate vs Iron Polysaccharide Complex for Iron-Deficiency Anemia

15Jun
2017

Effect of Low-Dose Ferrous Sulfate vs Iron Polysaccharide Complex on Hemoglobin Concentration in Young Children With Nutritional Iron-Deficiency Anemia: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

The JAMA Network – For the Media: Treating Nutritional Iron-Deficiency Anemia in Children (free)

Commentaries: Ferrous Sulfate Drops Tied to Higher Hemoglobin Increases in Kids with Anemia – Physician’s First Watch (free) AND Traditional treatment is better for iron-deficiency anaemia in children – OnMedica (free) AND Ferrous Sulfate Effective for Iron-Deficiency Anemia in Kids – Medscape (free registration required)

Researchers expected that Iron Polysaccharide Complex would restore hemoglobin more effectively, because it is designed to be tolerated better, but the proportion of infants and children with a complete resolution of iron-deficiency anemia was higher in the ferrous sulfate group (29 percent vs 6 percent).

 

Iron deficiency or anemia of inflammation?

4Jun
2017

Clinical updates in adult immune thrombocytopenia

4Jun
2017

Heparin-induced thrombocytopenia

4Jun
2017

HUS and atypical HUS

4Jun
2017

Cancer drugs are getting better and dearer

1Jun
2017

Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women With Mechanical Heart Valves

1Jun
2017

Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women With Mechanical Heart Valves – Journal of The American College of Cardiology (free)

Commentaries: Warfarin OK in Expectant Moms with Mechanical Heart Valve – MedPage Today (free registration required) AND Anticoagulation in Pregnant Women With Mechanical Valves – American College of Cardiology, Latest in Cardiology (free) (RT @keaglemd see Tweet)

In this meta-analysis, warfarin was associated with lower risk of adverse maternal outcomes, whereas LMWH was associated with lower risk of adverse fetal outcomes.

 

Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment

29May
2017

Thrombocytosis and cancer

29May
2017

Multiple Myeloma Guidelines

24May
2017

Perioperative management of patients on direct oral anticoagulants

24May
2017

Hodgkin Lymphoma – NCCN Clinical Practice Guidelines

12May
2017

Guideline for the Management of Fever and Neutropenia in Children

10May
2017

Management of severe perioperative bleeding

6May
2017

Donor Age and Sex Do Not Affect of Patients Receiving Transfusions

5May
2017

Association of Donor Age and Sex With Survival of Patients Receiving Transfusions – JAMA Internal Medicine (link to abstract – $ required for full-text)

Source: Blood Donor Age, Sex Do Not Affect Outcomes After All – Medscape (free registration required)

“After reviewing almost 1 million transfusions, the researchers concluded all donations are about the same” (RT @theheartorg see Tweet)

 

Management of Inherited Bleeding Disorders in Pregnancy

1May
2017

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage

27Apr
2017

Standardized Criteria for Palliative Care Consultation

24Apr
2017

Prospective, before-after cohort study: Standardized Criteria for Palliative Care Consultation on a Solid Tumor Oncology Service Reduces Downstream Health Care Use – Journal of Oncology Practice (free)

Editorial: Making the Right Thing Easier to Do: Standardized Integration of Oncology and Palliative Care – Journal of Oncology Practice (free)

Related Guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free)

Commentaries on the study: Standardized Palliative Care Consults Cut Cancer Readmissions – Also, less chemotherapy after discharge – MedPage Today (free registration required) AND Standardized Cancer Palliative Care Consults Linked to Stronger Home-Based Support – AJMC (free)

Patients with at least one of the following 4 criteria: 1) advanced solid tumor; 2) prior hospitalization within 30 days; 3) hospitalization > 7 days; or 4) active symptoms – received automatic palliative care consultation. The rates of 30-day readmissions dropped from 35% to 18% and chemotherapy after discharge dropped from 44% to 18%.

 

New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management

18Apr
2017

European Association of Urology releases its 1st thromboprophylaxis guideline

14Apr
2017

European Association of Urology releases its 1st thromboprophylaxis guideline (free)

 

Procedure-specific Risks of Thrombosis and Bleeding in Urological Cancer Surgery: Systematic Review and Meta-analysis – European Urology (free)

“Extended thromboprophylaxis is warranted in some procedures (eg, open and robotic cystectomy) but not others (eg, robotic prostatectomy without pelvic lymph node dissection in low-risk patients)

 

Procedure-specific Risks of Thrombosis and Bleeding in Urological Non-cancer Surgery: Systematic Review and Meta-analysis – European Urology (free)

“Extended prophylaxis is warranted for some procedures (eg, kidney transplantation procedures in high-risk patients) but not others (transurethral resection of the prostate and reconstructive female pelvic surgery in low-risk patients)”

 

Emergencies in Hematology and Oncology

11Apr
2017

Emergencies in Hematology and Oncology – Mayo Clinic Proceedings (free)

Comprehensive review covering the most common oncological emergencies.

 

Cancer patients have 55% greater risk of suicide

6Apr
2017

American College of Radiology (ACR) Appropriateness Criteria Adds Topics

4Apr
2017

ACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)

Browse Appropriateness Criteria Topics (free)

Source: Newswise

This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.

 

Eosinophilia in Primary Care

4Apr
2017

Anemia and blood transfusion in the critically ill patient with cardiovascular disease

3Apr
2017

Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease

30Mar
2017

Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease – Journal of the American College of Cardiology (free)

Source: SciCombinator

Except for patients with moderate/severe mitral stenosis or mechanical heart valves, who were excluded in most trials, high-dose NOACs was as effective and safe for patients with valvular heart disease as for patients without valvular disorders.

 

HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis

29Mar
2017

Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study – The BMJ (free)

Source: Richard Lehman’s weekly review

HERDOO2 rule stands for Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; or Older age, ≥65 years. The authors concluded that women with a first unprovoked VTE event and none or one of the HERDOO2 criteria have a low risk (3.0% per patient year) of recurrent VTE and can safely discontinue anticoagulants after completing short term treatment.

 

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