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Gynecology & Obstetrics (all articles)

SR | Automated mandatory bolus vs. basal infusion for maintenance of epidural analgesia in labor

20 Jun, 2023 | 12:24h | UTC

Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour – Cochrane Library

Summary: Do automated mandatory boluses of epidural medications provide superior labour pain relief than basal infusion? – Cochrane Library

 


Triple trouble | Uncovering the risks and benefits of early fetal reduction in trichorionic triplets in a large national Danish cohort study

19 Jun, 2023 | 13:39h | UTC

Triple trouble: Uncovering the risks and benefits of early fetal reduction in trichorionic triplets in a large national Danish cohort study – American Journal of Obstetrics & Gynecology

 


RCT | Increased detection of metastases via PET-CT alters treatment path in locally advanced breast cancer

16 Jun, 2023 | 14:02h | UTC

Impact of 18F-Labeled Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Versus Conventional Staging in Patients With Locally Advanced Breast Cancer – Journal of Clinical Oncology (link to abstract – $ for full-text)

 


M-A | Postpartum care up to 1 year after pregnancy

14 Jun, 2023 | 14:39h | UTC

Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-analysis – Agency for Healthcare Research and Quality

 


SR | Management of postpartum hypertensive disorders of pregnancy

14 Jun, 2023 | 14:37h | UTC

Management of Postpartum Hypertensive Disorders of Pregnancy – Agency for Healthcare Research and Quality

 


ASCO Guideline Update | Human epidermal growth factor receptor 2 testing in breast cancer

14 Jun, 2023 | 14:15h | UTC

Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology–College of American Pathologists Guideline Update – Journal of Clinical Oncology

Commentary: ASCO-CAP Guideline Update Confirms Previous Recommendations for HER2 Testing in Breast Cancer – ASCO Daily News

 


M-A | Elevated HbA1c in gestational diabetes mellitus tied to 1.7-fold rise in large for gestational age incidence

13 Jun, 2023 | 13:39h | UTC

Association between HbA1c Levels and Fetal Macrosomia and Large for Gestational Age Babies in Women with Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of 17,711 Women – Journal of Clinical Medicine

 


Guideline | Prevention and therapy of preterm birth

12 Jun, 2023 | 13:45h | UTC

Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG

Part 1: Recommendations on the Epidemiology, Etiology, Prediction, Primary and Secondary Prevention of Preterm Birth – Geburtshilfe und Frauenheilkunde

Part 2: Recommendations on the Tertiary Prevention of Preterm Birth and on the Management of Preterm Premature Rupture of Membranes – Geburtshilfe und Frauenheilkunde

 


SR | Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome

12 Jun, 2023 | 13:41h | UTC

Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults – Cochrane Library

Summary: Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome – Cochrane Library

 


Review | Pregnancy as an early cardiovascular moment: peripartum cardiovascular health

12 Jun, 2023 | 13:36h | UTC

Pregnancy as an Early Cardiovascular Moment: Peripartum Cardiovascular Health – Circulation Research

 

Commentary on Twitter

 


Podcast | Ascend your understanding of pelvic inflammatory disease

6 Jun, 2023 | 14:23h | UTC

#83: Ascend Your Understanding of Pelvic Inflammatory Disease (PID) – The Cribsiders

 


Brief Review | What BP target is appropriate for pregnant patients with mild chronic hypertension?

6 Jun, 2023 | 14:20h | UTC

What BP target is appropriate for pregnant patients with mild chronic hypertension? – Journal of Family Practice

 


Review | Patient-centered care in the management of cancer during pregnancy

6 Jun, 2023 | 14:10h | UTC

Patient-Centered Care in the Management of Cancer During Pregnancy – ASCO Educational Book

See other articles in the series: 2023 ASCO Educational Book

 


#ASCO23 – RCT | Simple hysterectomy shown non-inferior to radical hysterectomy in low-risk early-stage cervical cancer

5 Jun, 2023 | 13:43h | UTC

An international randomized phase III trial comparing radical hysterectomy and pelvic node dissection (RH) vs simple hysterectomy and pelvic node dissection (SH) in patients with low-risk early-stage cervical cancer (LRESCC):  A Gynecologic Cancer Intergroup study led by the Canadian Cancer Trials Group (CCTG CX.5-SHAPE). – American Society of Clinical Oncology (link to abstract – not published yet)

Commentaries:

SHAPE Trial: Radical Hysterectomy May Not Be Needed for Early-Stage, Low-Risk Cervical Cancer – ASCO Daily News

Simple Hysterectomy May Be a Safe Option for Patients With Early-Stage, Low-Risk Cervical Cancer – The ASCO Post

 


Review | Inflammatory lesions of the breast

2 Jun, 2023 | 12:10h | UTC

Inflammatory Lesions of the Breast – Archives of Pathology and Laboratory Medicine

 


M-A | Maternal alcohol consumption and the risk of miscarriage in the first and second trimesters

1 Jun, 2023 | 12:10h | UTC

Maternal alcohol consumption and the risk of miscarriage in the first and second trimesters: a systematic review and dose–response meta-analysis – Acta Obstetricia et Gynecologica Scandinavica

 


Cohort Study | Associations of menstrual cycle regularity and length with cardiovascular diseases

1 Jun, 2023 | 12:07h | UTC

Associations of Menstrual Cycle Regularity and Length With Cardiovascular Diseases: A Prospective Study From UK Biobank – Journal of the American Heart Association

News Release: Long or short menstrual cycles linked to higher risk of CVD including atrial fibrillation – American Heart Association

 


M-A | Labor induction at 39 weeks: improved outcomes but increased shoulder dystocia for nulliparous women

31 May, 2023 | 14:10h | UTC

Comparison of Maternal Labor-Related Complications and Neonatal Outcomes Following Elective Induction of Labor at 39 Weeks of Gestation vs Expectant Management: A Systematic Review and Meta-analysis – JAMA Network Open

 


Review | Managing menopausal symptoms, fertility, and bone health in breast cancer women on endocrine therapy

30 May, 2023 | 11:40h | UTC

Advances in the Management of Menopausal Symptoms, Fertility Preservation, and Bone Health for Women With Breast Cancer on Endocrine Therapy – ASCO Educational Book

 


WHO Report | Global progress in tackling maternal and newborn deaths stalls since 2015

25 May, 2023 | 11:36h | UTC

News Release: Global progress in tackling maternal and newborn deaths stalls since 2015: UN – World Health Organization

Report: Improving maternal and newborn health and survival and reducing stillbirth – Progress report 2023 – World Health Organization

 


A pragmatic approach to the management of menopause

25 May, 2023 | 11:30h | UTC

A pragmatic approach to the management of menopause – Canadian Medical Association Journal

News Release: Managing menopause: Hormone therapy is back – Canadian Medical Association Journal

 


RCT | Spironolactone enhances acne outcomes and offers a viable alternative to oral antibiotics

24 May, 2023 | 13:27h | UTC

Summary: The SAFA (Spironolactone for Adult Female Acne) trial was a multicenter, phase 3, double-blind, randomized controlled trial in England and Wales and evaluated the efficacy of spironolactone for treating adult women with acne vulgaris. A total of 410 women, aged ≥18 years and suffering from facial acne for a minimum of six months, were randomly assigned to receive either 50 mg/day of spironolactone or a placebo, increasing to 100 mg/day until week 24.

The primary outcome was measured by the Acne-Specific Quality of Life (Acne-QoL) symptom subscale score at week 12 and 24. The trial demonstrated that spironolactone improved Acne-QoL scores more effectively than the placebo, particularly at week 24. Additionally, more participants in the spironolactone group reported acne improvement, and treatment success was significantly higher in this group at week 12. Mild side effects, notably headaches, were more common in the spironolactone group.

The findings from the SAFA trial highlight spironolactone’s effectiveness, safety, and tolerability in treating adult women with acne vulgaris, suggesting it is a viable alternative to long-term antibiotic treatments. Future research is proposed on higher initial dosages of spironolactone, and its effects on different subgroups like patients with different ages, body mass index, and ethnicity.

Article: Effectiveness of spironolactone for women with acne vulgaris (SAFA) in England and Wales: pragmatic, multicentre, phase 3, double blind, randomised controlled trial – The BMJ

Editorial: What do we know about prescribing spironolactone for acne? – The BMJ

News Release: Non-antibiotic treatment for women with persistent acne shown to be effective – University of Southhampton

 


WHO Report | 152 million babies born preterm in the last decade

23 May, 2023 | 13:15h | UTC

News Release: 152 million babies born preterm in the last decade – World Health Organization

Report: Born too soon: decade of action on preterm birth – World Health Organization

 


Consensus Statement | Management of arrhythmias during pregnancy

23 May, 2023 | 13:00h | UTC

2023 HRS Expert Consensus Statement on the Management of Arrhythmias During Pregnancy – Heart Rhythm

News Release: Management of Arrhythmias During Pregnancy Consensus Statement Emphasizes Shared Decision-Making – European Heart Rhythm

 


USPSTF Draft Statement recommends biennial screening mammography for women ages 40 to 74 years

22 May, 2023 | 13:56h | UTC

Breast Cancer: Screening – U.S. Preventive Services Task Force

Critical perspectives on the statement:

Earlier screening for breast cancer: Benefits and harms – Lown Institute

Video: Mammography – Does it save lives? | The USPSTF is incorrect | I review ALL the data – By Dr. Vinay Prasad

Why more mammograms aren’t the solution to breast cancer – Vox

 


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