Gynecology & Obstetrics

Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome – Cochrane Library (free)

Summary: Metformin for ovulation induction in women with a diagnosis of polycystic ovary syndrome and subfertility – Cochrane Library (free)


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Cross-sectional imaging of acute gynaecologic disorders: CT and MRI findings with differential diagnosis – Insights into Imaging (free articles)

Part I: corpus luteum and haemorrhagic ovarian cysts, genital causes of haemoperitoneum and adnexal torsion

Part II: uterine emergencies and pelvic inflammatory disease


New baby: fads, fashions and evidence for new parents – Evidently Cochrane (free)


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Breast Conservation After Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: Surgical Results From the BrighTNess Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Despite effective therapy, US rate of breast conservation lower than other countries – Brigham and Women’s Hospital (free)


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External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Results mixed for twice-daily APBI in early breast cancer – MedicalXpress (free)


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Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial – The Lancet (link to abstract – $ for full-text)


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NICE Guideline: Menopause

6 Dec, 2019 | 10:50h | UTC

Supplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)

“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)


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Review: Cardiomyopathy and Pregnancy

27 Nov, 2019 | 07:39h | UTC

Review: Bladder Pain Syndrome in Women

24 Nov, 2019 | 20:34h | UTC

Bladder Pain Syndrome in Women – JAMA (free for a limited period)


Recurrence of breast cancer after regional or general anaesthesia: a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Anesthesia for breast cancer surgery has no influence on risk of tumor recurrence – Medical University of Vienna (free) AND Anesthesia Technique Flops in Large Breast Cancer Trial – MedPage Today (free registration required)


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Effectiveness of routine third trimester ultrasonography to reduce adverse perinatal outcomes in low risk pregnancy (the IRIS study): nationwide, pragmatic, multicentre, stepped wedge cluster randomised trial – The BMJ (free)

Commentary: Routine third trimester ultrasonography: Avoiding “too much too soon” – The BMJ Opinion (free)


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Special Issue: Obstetric Anesthesia

2 Oct, 2019 | 02:08h | UTC

Treatment of Vulvovaginal Atrophy – JAMA (free for a limited period)


C-section babies are missing key microbes – Nature News (free)

Original Study: Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth – Nature (link to abstract – $ for full-text)

Other Commentaries: Babies’ gut bacteria affected by delivery method, Baby Biome project shows – Wellcome Sanger Institute (free) AND Babies born by C-section have more potentially infectious bacteria in their guts – ScienceNews (free)

“UK study provides the best evidence yet that the way infants are born can alter their microbiomes — but the health effects are unclear.”


Sacrospinous hysteropexy versus vaginal hysterectomy with uterosacral ligament suspension in women with uterine prolapse stage 2 or higher: observational follow-up of a multicentre randomised trial – The BMJ (free)


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Prevention of postoperative adhesion reformation by intermittent intrauterine balloon therapy: a randomised controlled trial – British Journal of Obstetricians and Gynaecologists (link to abstract – $ for full-text)

Source: EvidenceAlerts


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Effects of maternal influenza vaccination on adverse birth outcomes: A systematic review and Bayesian meta-analysis – PLOS One (free)

Related Research: Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers (free)

Related ACOG Guideline: Influenza Vaccination During Pregnancy (free)

“maternal influenza vaccination is not associated with harmful effects on birth outcomes. The beneficial effects reported from previous studies on preterm birth, low birth weight, and fetal death could not be confirmed.”


NCCN Guidelines Insights: Ovarian Cancer

18 Aug, 2019 | 21:30h | UTC

Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery: A Prospective Multicenter Randomized Controlled Trial – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts


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Three versus five days of pivmecillinam for community-acquired uncomplicated lower urinary tract infection: A randomised, double-blind, placebo-controlled superiority trial – EClinicalMedicine (free)


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Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial – The Lancet (free)

Commentary: Oral regimen management of acute hypertension in pregnancy – The Lancet (free)


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Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries: Bayesian Network Meta-analyses of Randomized Clinical Trials – JAMA Network Open (free)


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The impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – for full-text)

Commentary: Night shifts, long hours linked to miscarriages and preterm births – Reuters (free)


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International consensus statement on the use of uterotonic agents during caesarean section – Anaesthesia (free)


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