Gynecology & Obstetrics

Perspective: Why Are Mothers Still Passing Syphilis to Their Babies? – JAMA (free for a limited period)

Related: A Rising Threat to Pregnant Women: Syphilis – The New York Times (10 articles per month are free)


Primary cervical screening with high risk human papillomavirus testing: observational study – The BMJ (free)

Commentaries: HPV cervical screening test switch ‘effective’, says pilot study – Cancer Research UK (free) AND Cervical screening intervals could be safely extended to at least five years – Pulse (free)

Related: USPSTF Statement: Screening for Cervical Cancer (free guidance and commentaries) AND Study: Little Benefit in Screening Women Aged 55 with a Negative HPV DNA test (link to abstract and commentaries) AND Randomized Trial: Cervical Cancer Screening with Cervical HPV Testing vs Cytology Testing (link to abstract and commentaries)

“The lower incidence of cervical intraepithelial neoplasia grade 3 or worse and cervical cancer at present screening intervals would strongly support the safety of extending the intervals to at least five years without increasing the risk of potentially life-threatening disease.”


When Is the Surgeon Too Old to Operate? – The New York Times (free)

Related: Perspective: Assessing the Performance of Aging Surgeons (free for a limited period) AND Observational Study: Age and Sex of Surgeons and Mortality of Older Surgical Patients (free study and commentary) AND The Elderly and Driving: When Is It Time to Hit the Brakes? – The New York Times (10 articles per month are free)


Related Commentary on Twitter

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement – JAMA (free)

“The USPSTF recommends prophylactic ocular topical medication for all newborns to prevent gonococcal ophthalmia neonatorum. (A recommendation)”


ACOG Guideline: Prepregnancy Counseling

18 Jan, 2019 | 01:00h | UTC

Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza – Clinical Infectious Diseases (free)

News Release: Flu is Serious for Pregnant Women and Others at High Risk: Testing and Treatment are Key, Say IDSA Guidelines (free)


Related Commentary on Twitter


Associations Between Breast Cancer Survivorship and Adverse Mental Health Outcomes: A Systematic Review – JNCI: Journal of the National Cancer Institute (free)

Commentary: Adverse Mental Health Outcomes in Breast Cancer Survivors – The ASCO Post (free)

“There is compelling evidence of an increased risk of anxiety, depression and suicide, and neurocognitive and sexual dysfunctions in breast cancer survivors compared with women with no prior cancer.”


Risk of Malignant Ovarian Cancer Based on Ultrasonography Findings in a Large Unselected Population – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Most simple ovarian cysts require no treatment, surveillance – UPI (free) AND Less surveillance needed for simple ovarian cysts – University of California, San Francisco (free)

“New study finds that simple cysts should be considered normal and ignored” (from The University of California)


The troubling epidemic of unnecessary C-sections around the world, explained – VOX (free)

Related WHO Recommendations: Non-Clinical Interventions to Reduce Unnecessary Cesarean Sections (free guideline and commentaries)

Related The Lancet Series: Optimising Cesarean Section Use (free articles)

Related Cochrane Review: Non‐Clinical Interventions for Reducing Unnecessary Caesarean Section (free review and summary)

“The C-section rate has doubled in less than a generation, from 12 percent of all births in 2000 to 21 percent in 2015.”


Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer – New England Journal of Medicine (free for a limited period)

Commentaries: Not So Fast With Immune Therapy For Breast Cancer – Forbes (free) AND Immunotherapy drugs show some promise against breast cancer – STAT (free)

“…the benefit for most women was small, raising questions about whether the treatment is worth its high cost and side effects.” (from STAT)


Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women – Cochrane Library (free)

“Based on the data available, we can be confident that pelvic floor muscle training can cure or improve symptoms of stress urinary incontinence and all other types of urinary incontinence”


Association between maternal gluten intake and type 1 diabetes in offspring: national prospective cohort study in Denmark – The BMJ (free)

Editorial: Dietary gluten and type 1 diabetes (free for a limited period)

Commentaries: Expert reaction to research on high gluten intake during pregnancy and type 1 diabetes in children – Science Media Centre (free) AND Higher Gluten Intake in Pregnancy Tied to Increased Diabetes Risk in Offspring – Physician’s First Watch (free) AND High gluten intake during pregnancy associated with diabetes – OnMedica (free)’

“As such these results, whilst well executed and very interesting, would need to be confirmed within independent similarly sized or bigger studies as stated by the authors themselves.” (from Science Media Centre)


Screening for Syphilis Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement – JAMA (free)

Editorial: Congenital Syphilis—Still a Shadow on the Land (free)

“The USPSTF recommends early screening for syphilis infection in all pregnant women. (A recommendation)”


Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women’s Health Initiative – Journal of the American Heart Association (free)

Commentaries: Breastfeeding linked to lower stroke risk – Reuters (free) AND Breastfeeding may help protect mothers against stroke – AHA News (free)

“…ultimately, the study is observational, which means that it can only prove that breast feeding is associated with lower risk of stroke as opposed to being the cause of the lowered risk.” (from Reuters)


ESMO Guideline: Advanced Breast Cancer

26 Jul, 2018 | 17:56h | UTC

Long-acting Reversible Contraception—Highly Efficacious, Safe, and Underutilized – JAMA (free for a limited period)

Clinical Review Audio: Return of the IUD: Long-acting Reversible Contraception Is Safe and Effective (free)


Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study – The BMJ (free)

In this large international, population-based database, no evidence was found of an overall increased risk of congenital anomalies after first trimester metformin exposure.


HPV Vaccination: Balancing Facts

6 Jul, 2018 | 03:10h | UTC

Editorial: HPV vaccination: balancing facts – Cochrane Library (free)

Related Cochrane Review: Prophylactic Vaccination Against HPV to Prevent Cervical Cancer (link to review and commentaries)


AAP Clinical Report: The Prenatal Visit

29 Jun, 2018 | 03:07h | UTC