Gynecology & Obstetrics

Special Issue: Obstetric Anesthesia

2 Oct, 2019 | 02:08h | UTC

Treatment of Vulvovaginal Atrophy – JAMA (free for a limited period)

 


C-section babies are missing key microbes – Nature News (free)

Original Study: Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth – Nature (link to abstract – $ for full-text)

Other Commentaries: Babies’ gut bacteria affected by delivery method, Baby Biome project shows – Wellcome Sanger Institute (free) AND Babies born by C-section have more potentially infectious bacteria in their guts – ScienceNews (free)

“UK study provides the best evidence yet that the way infants are born can alter their microbiomes — but the health effects are unclear.”

 


Sacrospinous hysteropexy versus vaginal hysterectomy with uterosacral ligament suspension in women with uterine prolapse stage 2 or higher: observational follow-up of a multicentre randomised trial – The BMJ (free)

 

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Prevention of postoperative adhesion reformation by intermittent intrauterine balloon therapy: a randomised controlled trial – British Journal of Obstetricians and Gynaecologists (link to abstract – $ for full-text)

Source: EvidenceAlerts

 

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Effects of maternal influenza vaccination on adverse birth outcomes: A systematic review and Bayesian meta-analysis – PLOS One (free)

Related Research: Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers (free)

Related ACOG Guideline: Influenza Vaccination During Pregnancy (free)

“maternal influenza vaccination is not associated with harmful effects on birth outcomes. The beneficial effects reported from previous studies on preterm birth, low birth weight, and fetal death could not be confirmed.”

 


NCCN Guidelines Insights: Ovarian Cancer

18 Aug, 2019 | 21:30h | UTC

Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery: A Prospective Multicenter Randomized Controlled Trial – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts

 

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Three versus five days of pivmecillinam for community-acquired uncomplicated lower urinary tract infection: A randomised, double-blind, placebo-controlled superiority trial – EClinicalMedicine (free)

 

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Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial – The Lancet (free)

Commentary: Oral regimen management of acute hypertension in pregnancy – The Lancet (free)

 

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Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries: Bayesian Network Meta-analyses of Randomized Clinical Trials – JAMA Network Open (free)

 

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The impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – for full-text)

Commentary: Night shifts, long hours linked to miscarriages and preterm births – Reuters (free)

 

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International consensus statement on the use of uterotonic agents during caesarean section – Anaesthesia (free)

 

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State of The Art Review: Pre-eclampsia: pathophysiology and clinical implications – The BMJ (free for a limited period)

 


Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children – Nature Medicine (link to abstract – $ for full-text)

News Release: A third of children up to age 3 exposed to Zika in-utero have neurological problems – UCLA (free) AND Maternal Zika infection tied to poor development in 32% of tots – CIDRAP (free)

 

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MRI versus mammography for breast cancer screening in women with familial risk (FaMRIsc): a multicentre, randomised, controlled trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: MRI Breast Screening Better for Women With Familial Cancer Risk – MedPage Today (free registration required)

 

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Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentaries: Vaccination programs substantially reduce HPV infections and precancerous cervical lesions – Laval University (free) AND Hopes raised of cervical cancer eradication – BBC (free) AND Study shows major real-world impact of cervical cancer vaccines – Reuters (free)

 

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ESMO Guideline: Early Breast Cancer

24 Jun, 2019 | 01:49h | UTC

Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials – The BMJ (free)

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Review: Menopausal Hormone Therapy

31 May, 2019 | 06:30h | UTC

Menopausal Hormone Therapy – JAMA (free for a limited period)

Podcast: Menopausal Hormone Therapy (free audio)

 


Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial – The Lancet (free)

Invited Commentary: Antibiotics for operative vaginal delivery: practice-changing data – The Lancet (free)

 

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Estimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies: A Cost-effectiveness Analysis – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Screening Options for Preventing Cervical Cancer (free for a limited period)

Author Interview: Estimated Quality of Life and Economic Outcomes Associated With Cervical Cancer Screening (free audio)

“Cytologic testing every 3 years and low-cost high-risk human papillomavirus testing every 5 years both may be considered reasonable cervical cancer screening options.”

 

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Association between Apgar scores of 7 to 9 and neonatal mortality and morbidity: population based cohort study of term infants in Sweden – The BMJ (free)

Commentaries: The Apgar score and association with neonatal mortality and morbidity – The BMJ Opinion (free) AND Lower ‘normal’ Apgar scores linked to poorer outcomes – OnMedica (free)

 

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Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes – JAMA (free for a limited period)

Editorial: Prepregnancy Body Mass Index, Weight Gain During Pregnancy, and Health Outcomes (free for a limited period)

“Optimal gestational weight gain ranges were 14.0 kg to less than 16.0 kg for women categorized as underweight; 10.0 kg to less than 18.0 kg for normal weight; 2.0 kg to less than 16.0 kg for overweight; 2.0 kg to less than 6.0 kg for obesity grade 1; weight loss or gain of 0 kg to less than 4.0 kg for obesity grade 2; and weight gain of 0 kg to less than 6.0 kg for obesity grade 3.”

 


Risk‐reducing medications for primary breast cancer: a network meta‐analysis – Cochrane Library (free)

Summary: Medicines to prevent breast cancer in women at above-average risk of developing breast cancer – Cochrane Library (free)

 

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Effects of repeat prenatal corticosteroids given to women at risk of preterm birth: An individual participant data meta-analysis – PLOS Medicine (free)

Source: EvidenceAlerts

“Our findings suggest that to provide clinical benefit with the least effect on growth, the number of repeat treatment courses should be limited to a maximum of three and the total dose to between 24 mg and 48 mg.”