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NEWS - Gynecology & Obstetrics

Associations Between Breast Cancer Survivorship and Adverse Mental Health Outcomes: A Systematic Review – JNCI: Journal of the National Cancer Institute (free)

Commentary: Adverse Mental Health Outcomes in Breast Cancer Survivors – The ASCO Post (free)

“There is compelling evidence of an increased risk of anxiety, depression and suicide, and neurocognitive and sexual dysfunctions in breast cancer survivors compared with women with no prior cancer.”

 


Risk of Malignant Ovarian Cancer Based on Ultrasonography Findings in a Large Unselected Population – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Most simple ovarian cysts require no treatment, surveillance – UPI (free) AND Less surveillance needed for simple ovarian cysts – University of California, San Francisco (free)

“New study finds that simple cysts should be considered normal and ignored” (from The University of California)

 


The troubling epidemic of unnecessary C-sections around the world, explained – VOX (free)

Related WHO Recommendations: Non-Clinical Interventions to Reduce Unnecessary Cesarean Sections (free guideline and commentaries)

Related The Lancet Series: Optimising Cesarean Section Use (free articles)

Related Cochrane Review: Non‐Clinical Interventions for Reducing Unnecessary Caesarean Section (free review and summary)

“The C-section rate has doubled in less than a generation, from 12 percent of all births in 2000 to 21 percent in 2015.”

 


Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer – New England Journal of Medicine (free for a limited period)

Commentaries: Not So Fast With Immune Therapy For Breast Cancer – Forbes (free) AND Immunotherapy drugs show some promise against breast cancer – STAT (free)

“…the benefit for most women was small, raising questions about whether the treatment is worth its high cost and side effects.” (from STAT)

 


Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women – Cochrane Library (free)

“Based on the data available, we can be confident that pelvic floor muscle training can cure or improve symptoms of stress urinary incontinence and all other types of urinary incontinence”

 


Association between maternal gluten intake and type 1 diabetes in offspring: national prospective cohort study in Denmark – The BMJ (free)

Editorial: Dietary gluten and type 1 diabetes (free for a limited period)

Commentaries: Expert reaction to research on high gluten intake during pregnancy and type 1 diabetes in children – Science Media Centre (free) AND Higher Gluten Intake in Pregnancy Tied to Increased Diabetes Risk in Offspring – Physician’s First Watch (free) AND High gluten intake during pregnancy associated with diabetes – OnMedica (free)’

“As such these results, whilst well executed and very interesting, would need to be confirmed within independent similarly sized or bigger studies as stated by the authors themselves.” (from Science Media Centre)

 


Screening for Syphilis Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement – JAMA (free)

Editorial: Congenital Syphilis—Still a Shadow on the Land (free)

“The USPSTF recommends early screening for syphilis infection in all pregnant women. (A recommendation)”

 


Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women’s Health Initiative – Journal of the American Heart Association (free)

Commentaries: Breastfeeding linked to lower stroke risk – Reuters (free) AND Breastfeeding may help protect mothers against stroke – AHA News (free)

“…ultimately, the study is observational, which means that it can only prove that breast feeding is associated with lower risk of stroke as opposed to being the cause of the lowered risk.” (from Reuters)

 


Long-acting Reversible Contraception—Highly Efficacious, Safe, and Underutilized – JAMA (free for a limited period)

Clinical Review Audio: Return of the IUD: Long-acting Reversible Contraception Is Safe and Effective (free)

 


Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study – The BMJ (free)

In this large international, population-based database, no evidence was found of an overall increased risk of congenital anomalies after first trimester metformin exposure.

 


Editorial: HPV vaccination: balancing facts – Cochrane Library (free)

Related Cochrane Review: Prophylactic Vaccination Against HPV to Prevent Cervical Cancer (link to review and commentaries)

 


Association of Hypertensive Disorders of Pregnancy With Risk of Neurodevelopmental Disorders in Offspring: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)

Commentary: Hypertension in Pregnancy Tied to Autism, ADHD – MedPage Today (free registration required)

“Researchers call for greater pediatric surveillance of infants in hypertensive moms” (from MedPage Today)

 


Aspirin Effect on Adverse Pregnancy Outcomes Associated With Stage 1 Hypertension in a High-Risk Cohort – Hypertension (link to abstract – $ for full-text)

Commentary: Low-dose aspirin could help pregnant women with high blood pressure avoid a dangerous condition – AHA News (free)

Related Study: Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia (free article and commentaries)

“These findings emphasize the importance of recognition of stage 1 hypertension as an additive risk factor in women at high risk for preeclampsia and the benefit of aspirin”.

 


ASCO 2018: Shortening Adjuvant Trastuzumab to 6 Months in Patients With HER2-Positive Early Breast Cancer Is Effective and Reduces Cardiac Toxicities – The ASCO Post (free)

Commentaries: Test of Herceptin Finds Briefer Treatment Can Work, With Fewer Side Effects – NPR (free) AND Shorter drug treatment OK for many breast cancer patients – Associated Press (free) AND For Women With Early Breast Cancer, Herceptin Treatment Can Be Much Shorter – The New York Times (10 articles per month are free)

““For women with early-stage breast cancer who needed the drug Herceptin, 6 months of treatment were as good as 12, a major study found. Less risk of side effects, less cost, less time “being a patient.”” (via @NYTHealth see Tweet)

 


Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis – Cochrane Library (free for a limited period)

News Release: Featured Review: Uterotonic agents for preventing postpartum haemorrhage – Cochrane Library (free)

Commentary: Review finds more effective drugs to stop bleeding after childbirth – University of Birmingham (free)

“New Cochrane Review suggests ergometrine plus oxytocin; misoprostol plus oxytocin; & carbetocin on its own, are more effective drugs for reducing excessive bleeding at childbirth rather than the current standard use of oxytocin on its own” (via @CochraneUK see Tweet)

 


USPSTF Draft Recommendation Statement: Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: Screening (free)

Commentaries: USPSTF urges abuse screening for reproductive-aged women – MedicalXpress (free) AND USPSTF Recommends Screening for Partner Violence in Reproductive-Aged Women – Clinical Advisor (free)

“The USPSTF recommends that clinicians screen for intimate partner violence (IPV) in women of reproductive age and provide or refer women who screen positive to ongoing support services.”

 


Antifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)

“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)

 


The Lancet Editorial: Abortion: access and safety worldwide (free)

 


FDA In Brief: FDA updates public information about known risk of lymphoma from breast implants (free) AND Breast Implant-Associated Anaplastic Large Cell Lymphoma – FDA Update (free)

Commentaries: More Cases Are Reported of Unusual Cancer Linked to Breast Implants – The New York Times (10 articles per month are free) AND Implant-Related Lymphoma Cases Rise – More than 400 cases reported to FDA – MedPage Today (free)

“Some 400 to 500 women worldwide have an unusual type of lymphoma linked to breast implants with textured surfaces. Experts say women considering implants should be told”. (via @NYTHealth see Tweet)

 


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