Global & Public Health

The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017 – The Lancet Oncology (free)

Commentaries: Global burden of childhood cancer: growing, but controllable – The Lancet Oncology (free) AND Globally, more than 11 million years of healthy life lost due to childhood cancer in 2017 – The Lancet (free)


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Immunogenicity of Fractional-Dose Vaccine during a Yellow Fever Outbreak — Final Report – New England Journal of Medicine (free)

“These findings support the use of fractional-dose vaccination for outbreak control.”


New Protocol For HIV Prevention Drug Reduces The Number Of Pills Required – Kaiser Health News (free)

Related: British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject) AND USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection (free guideline and commentaries)

“both organizations now endorse a strategy that requires taking just four pills timed to a specific sexual encounter — two within two to 24 hours before sex and one on each of the two following days… The new strategy, called “2-1-1” or “on-demand” PrEP, is becoming popular overseas but has gotten little traction in the United States thus far.”


Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries: Bayesian Network Meta-analyses of Randomized Clinical Trials – JAMA Network Open (free)


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Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial – The Lancet (free)

Commentary: A shorter course for anti-relapse therapy against vivax malaria – The Lancet (free)


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Opinion: Mandate Vaccination with Care

29 Jul, 2019 | 20:01h | UTC

WHO recommends dolutegravir as preferred HIV treatment option in all populations – World Health Organization (free)


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Mapping exclusive breastfeeding in Africa between 2000 and 2017 – Nature Medicine (free)

News Release: Despite substantial progress, only three African nations expected to meet global breastfeeding goals – Institute for Health Metrics and Evaluation (free)


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The Lancet Series: Oral Health

21 Jul, 2019 | 21:24h | UTC

Oral Health – The Lancet (free articles and commentaries – registration required)


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The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness – The Lancet Psychiatry (free registration required)

Executive Summary and Podcast: A blueprint for protecting physical health in people with mental illness (free summary, audio and other resources)

Commentaries: Global commission into health inequities of mental illness gives blueprint for change – NICM Health Research Institute at Western Sydney University (free) AND People with mental illness experience poorer physical health, and the gap may be getting worse, experts say – ABC News (free) AND Why people with mental illness may face poorer physical health and early death – CNN (free)

Related WHO Guideline: Management of Physical Health Conditions in Adults with Severe Mental Disorders (free)


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Physician Burnout: A Global Crisis

12 Jul, 2019 | 07:57h | UTC

Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children – Nature Medicine (link to abstract – $ for full-text)

News Release: A third of children up to age 3 exposed to Zika in-utero have neurological problems – UCLA (free) AND Maternal Zika infection tied to poor development in 32% of tots – CIDRAP (free)


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Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling – The Lancet Infectious Diseases (free)

Commentaries: The burden of latent multidrug-resistant tuberculosis – The Lancet Infectious Diseases (free)


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Mass Drug Administration for Scabies

28 Jun, 2019 | 07:43h | UTC

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentaries: Vaccination programs substantially reduce HPV infections and precancerous cervical lesions – Laval University (free) AND Hopes raised of cervical cancer eradication – BBC (free) AND Study shows major real-world impact of cervical cancer vaccines – Reuters (free)


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Mapping the global prevalence, incidence, and mortality of Plasmodium falciparum, 2000–17: a spatial and temporal modelling study – The Lancet (free)

Related Study: Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000–17: a spatial and temporal modelling study – The Lancet (free)

Invited Commentary: New malaria maps (free)

News Release: New High-Resolution Global Maps Show How to Defeat Malaria – The Malaria Atlas Project (free)

See also: The Malaria Atlas Project Website (free resources) AND Explorer Tool (free)


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Wellcome Global Monitor How does the world feel about science and health? (free PDF)

Report Summary: Wellcome Global Monitor 2018 (free)

News Release: How much does the world trust medical experts and vaccines? (free)

Commentaries: Japan and Ukraine most likely to doubt safety of vaccines – Nature (free) AND Global trust strong in healthcare, scientists, vaccines—with exceptions – CIDRAP (free) AND Eroding trust in vaccines leaves populations vulnerable, global study finds – Reuters (free) AND Vaccines: Low trust in vaccination ‘a global crisis’ – BBC (free)


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Editorial: ICD 11

11 Jun, 2019 | 03:13h | UTC

ICD 11 – The Lancet (free)

Related: WHO: ICD-11 is Here! (free resources)


Longer-Term Assessment of Azithromycin for Reducing Childhood Mortality in Africa – New England Journal of Medicine (free)

Related: Macrolide Resistance in MORDOR I — A Cluster-Randomized Trial in Niger – New England Journal of Medicine (free)


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Does the news reflect what we die from? – Our World in Data (free)

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The Ongoing Ebola Epidemic in the Democratic Republic of Congo, 2018–2019 – New England Journal of Medicine (free)


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Cancer Control in Low- and Middle-Income Countries: Is It Time to Consider Screening? – Journal of Global Oncology (free)

“the placement of priority on early detection cannot be assumed to be effective in LMICs, where limited downstream resources may be overwhelmed by the inevitable increases in number of diagnoses.”


Geospatial, racial, and educational variation in firearm mortality in the USA, Mexico, Brazil, and Colombia, 1990–2015: a comparative analysis of vital statistics data – The Lancet Public Health (free)

Commentaries: Making the case for a world without guns – The Lancet Public Health (free) AND Firearm mortality highest in young men, and is associated with race and education – The Lancet (free)


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Fighting Ebola When Mourners Fight the Responders – The New York Times (10 articles per month are free)

Related: DRC Ebola cases top 1,800 amid burial team attacks – CIDRAP (free)

“An Ebola outbreak in eastern Congo — the second-largest in history — is escalating in part because locals don’t trust health workers and government officials.”


Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017 – Nature (free)

Commentaries: ‘Striking’ differences in rates of HIV/AIDS within African nations – Institute for Health Metrics and Evaluation (free) AND New HIV Map Offers Most Detailed Look Yet At The Epidemic – NPR (free)


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Estimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies: A Cost-effectiveness Analysis – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Screening Options for Preventing Cervical Cancer (free for a limited period)

Author Interview: Estimated Quality of Life and Economic Outcomes Associated With Cervical Cancer Screening (free audio)

“Cytologic testing every 3 years and low-cost high-risk human papillomavirus testing every 5 years both may be considered reasonable cervical cancer screening options.”


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Study: Alcohol-related Harm to Others

13 May, 2019 | 01:08h | UTC

Report: Access Barriers to Antibiotics

10 May, 2019 | 04:51h | UTC

Implementation manual to prevent and control the spread of carbapenem-resistant organisms at the national and health care facility level – World Health Organization (free PDF manual and resources)

Related Systematic Review: Control of Carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa in Healthcare Facilities – Clinical Infectious Diseases (free)

See also: Prevention and Treatment of Surgical Site Infections (free guidelines on the subject)


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Efficacy of population‐wide diabetes and obesity prevention programs: An overview of systematic reviews on proximal, intermediate, and distal outcomes and a meta‐analysis of impact on BMI – Obesity Reviews (free)


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A Global Review of Food-Based Dietary Guidelines – Advances in Nutrition (free)


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WHO World Immunization Week

26 Apr, 2019 | 02:12h | UTC

World Immunization Week, 24 – 30 April 2019 – World Health Organization (free resources)

See also: #vaccineswork (free text and infographics)


WHO: Malaria Vaccine Pilot Launched

25 Apr, 2019 | 06:35h | UTC

Healthcare in The Age Of Personalization

20 Apr, 2019 | 14:29h | UTC

Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study – The Lancet (free)

Commentaries: Population versus individual protection by pneumococcal conjugate vaccination – The Lancet (free) AND PCV10 pneumococcal vaccine has big impact in Kenya, even among unvaccinated individuals – Johns Hopkins University Bloomberg School of Public Health (free)


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Measles cases are up nearly 300% from last year. This is a global crisis – CNN (free)

WHO Statement: New measles surveillance data for 2019 – World Health Organization (free)

By Henrietta H Fore (executive director of UNICEF) and Tedros Adhanom Ghebreyesus (director general of the World Health Organization).


Effect of Text Messaging on Risk Factor Management in Patients With Coronary Heart Disease: The CHAT Randomized Clinical Trial – Circulation: Cardiovascular Quality and Outcomes (free)

Editorial: The CHAT Trial:Time for a Heart to Heart Talk (free)

Very important negative study.


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A Mysterious Infection, Spanning the Globe in a Climate of Secrecy – The New York Times (10 articles per month are free)

Related: CDC Guideline: Candida auris (free) AND A ‘perfect storm’ superbug: How an invasive fungus got health officials’ attention (free) AND Review: Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally (free) AND Epidemiology, Clinical Characteristics, Resistance, and Treatment of Infections by Candida Auris (free)

“The rise of Candida auris embodies a serious and growing public health threat: drug-resistant germs.”


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State of Global Air 2019 Report

4 Apr, 2019 | 22:21h | UTC