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Geriatrics

#EULAR2022 – RCT: Low dose, add-on prednisolone in patients with rheumatoid arthritis over 65 years.

6 Jun, 2022 | 11:51h | UTC

Low dose, add-on prednisolone in patients with rheumatoid arthritis aged 65+: the pragmatic randomised, double-blind placebo-controlled GLORIA trial – Annals of Rheumatic Diseases

Commentaries:

Chronic, low-dose glucocorticoid benefits outweigh harms in senior patients with RA – medwire News

Trial Upends Guidelines on Long-Term Steroids in Rheumatoid Arthritis — Vindication for clinicians who ignored official recommendations – MedPage Today (free registration required)

 


Nationwide cohort study: Association between medical androgen deprivation therapy and long-term cardiovascular disease and all-cause mortality in nonmetastatic prostate cancer.

3 Jun, 2022 | 11:10h | UTC

Association between medical androgen deprivation therapy and long-term cardiovascular disease and all-cause mortality in nonmetastatic prostate cancer – International Journal of Cancer

Commentary: ADT for Prostate Cancer: What’s the Risk on the Heart? – Medscape (free registration required)

 


Review: Skeletal aging.

2 Jun, 2022 | 10:50h | UTC

Skeletal Aging – Mayo Clinic Proceedings

 


Effectiveness and characteristics of physical fitness training on aerobic fitness in vulnerable older adults: an umbrella review of systematic reviews.

2 Jun, 2022 | 10:16h | UTC

Effectiveness and characteristics of physical fitness training on aerobic fitness in vulnerable older adults: an umbrella review of systematic reviews – BMJ Open

 


Cohort Study: Evaluation of neurologic and psychiatric outcomes after hospital discharge among adult survivors of cardiac arrest.

2 Jun, 2022 | 10:15h | UTC

Evaluation of Neurologic and Psychiatric Outcomes After Hospital Discharge Among Adult Survivors of Cardiac Arrest – JAMA Network Open

 


Cohort Study: Complicated carotid artery plaques and risk of recurrent ischemic stroke or TIA.

1 Jun, 2022 | 11:19h | UTC

Complicated Carotid Artery Plaques and Risk of Recurrent Ischemic Stroke or TIA – Journal of the American College of Cardiology

Commentary: Complicated Carotid Plaques and Risk of Recurrent Ischemic Stroke or TIA – American College of Cardiology

 

Commentary on Twitter

 


Association between retinal layer thickness and cognitive decline in older adults.

1 Jun, 2022 | 11:13h | UTC

Association Between Retinal Layer Thickness and Cognitive Decline in Older Adults – JAMA Ophthalmology

Commentaries:

Retinal Layer Thickness Linked to Risk of Cognitive Decline – NeurologyToday

Retinal Layer Thickness Linked to Cognitive Decline in Older Adults – HealthDay

 

Commentary on Twitter

 


Cohort Study: Taking 5-ARIs for BPH is not associated with increased mortality in prostate cancer.

1 Jun, 2022 | 10:59h | UTC

News Release: Taking 5-ARIs for BPH is not associated with increased mortality in prostate cancer – Karolinska Institute

Original Study: Association of 5α-Reductase Inhibitors With Prostate Cancer Mortality – JAMA Oncology (link to abstract – $ for full-text)

Authors Interview: Association of 5α-Reductase Inhibitors With Prostate Cancer Mortality – JAMA

Commentary: Large study finds no increased risk for prostate cancer death with 5-ARI use – medwire News

 

Commentary on Twitter

 


Most doctors still believe in prescribing unnecessary antibiotics to treat asymptomatic bacteriuria, study suggests.

31 May, 2022 | 11:31h | UTC

News Release: Most doctors still believe in prescribing unnecessary antibiotics to treat asymptomatic infections, study suggests – University of Maryland School of Medicine

Original Study: Exploration of Primary Care Clinician Attitudes and Cognitive Characteristics Associated With Prescribing Antibiotics for Asymptomatic Bacteriuria – JAMA Network Open

 

Commentary on Twitter

 


Delirium: How can we protect our patients? Detection and treatment strategies.

31 May, 2022 | 11:10h | UTC

Delirium: How Can We Protect Our Patients? Detection and Treatment Strategies – ICU Management & Practice

Related:

Less pharmacotherapy is more in delirium – Intensive Care Medicine

Pharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients – Cochrane Library

Delirium in critical illness: clinical manifestations, outcomes, and management – Intensive Care Medicine

Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review – Critical Care

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis – Intensive Care Medicine

Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine

 


Evidence-based recommendations on texture modified foods and thickened liquids for adults with oropharyngeal dysphagia – “There is no convincing evidence that thickened liquid or texture modified diet prevents death or pneumonia nor improves the quality of life, nutritional status, or oral intake in individuals with OD”.

30 May, 2022 | 11:54h | UTC

Second update of a systematic review and evidence-based recommendations on texture modified foods and thickened liquids for adults (above 17 years) with oropharyngeal dysphagia – Clinical Nutrition ESPEN

 


Editorial: Chance encounters, overdiagnosis, and overtreatment in orthopedic surgery.

30 May, 2022 | 11:43h | UTC

Editorial: Chance Encounters, Overdiagnosis, and Overtreatment – Clinical Orthopaedics and Related Research

 

Commentary on Twitter

 


Cohort Study: Seven healthy habits linked to lower risk of dementia in those with genetic risk.

30 May, 2022 | 10:54h | UTC

News Release: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology

Original Study: Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text)

Commentary: Healthy Lifestyle May Lower Dementia Risk Despite Genetics – HealthDay

 

Commentary on Twitter

 


Cohort Study: Long-term outcomes associated with open vs. endovascular abdominal aortic aneurysm repair.

30 May, 2022 | 10:37h | UTC

Long-term Outcomes Associated With Open vs Endovascular Abdominal Aortic Aneurysm Repair in a Medicare-Matched Database – JAMA Network Open

Commentaries:

Using Registry Data to Fill Blind Spots From Randomized Trials of Abdominal Aortic Aneurysm Repair – JAMA Network Open

Long-Term Outcomes Associated With Open vs. Endovascular AAA Repair – American College of Cardiology

 


Recommendations for whole genome sequencing in diagnostics for rare diseases.

27 May, 2022 | 11:16h | UTC

Recommendations for whole genome sequencing in diagnostics for rare diseases – European Journal of Human Genetics

 


Guideline on wound healing interventions to enhance healing of diabetic foot ulcers.

26 May, 2022 | 10:46h | UTC

Australian guideline on wound healing interventions to enhance healing of foot ulcers: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease – Journal of Foot and Ankle Research

 


Guidelines on the management of lumbar spinal stenosis.

26 May, 2022 | 10:44h | UTC

Japanese Orthopaedic Association (JOA) clinical practice guidelines on the management of lumbar spinal stenosis, 2021 – Secondary publication – Journal of Orthopaedic Science

 


USPSTF Recommendation Statement: The current evidence is insufficient to make a recommendation about screening for impaired visual acuity in older adults.

25 May, 2022 | 11:44h | UTC

Screening for Impaired Visual Acuity in Older Adults: US Preventive Services Task Force Recommendation Statement – JAMA

Editorials:

Visual Acuity Screening in Older Adults – JAMA Ophthalmology

Screening for Impaired Visual Acuity in Older Adults – JAMA

Vision Impairment Has Implications for Aging and Health Outcomes, Beyond Ophthalmology – JAMA Network Open

Evidence Report: Screening for Impaired Visual Acuity in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Patient Page: Screening for Impaired Visual Acuity in Older Adults – JAMA

Author Interview: USPSTF Recommendations: Screening for Primary Open-Angle Glaucoma and Screening for Impaired Visual Acuity in Older Adults – JAMA

 


USPSTF Recommendation Statement: The current evidence is insufficient to make a recommendation about screening for primary open-angle glaucoma in adults.

25 May, 2022 | 11:46h | UTC

Screening for Primary Open-Angle Glaucoma: US Preventive Services Task Force Recommendation Statement – JAMA

Editorials:

Identifying Glaucoma in Primary Care Offices – JAMA Ophthalmology

Screening for Glaucoma – JAMA

Evidence Report: Screening for Glaucoma in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Patient Page: Screening for Primary Open-Angle Glaucoma – JAMA

Author Interview: USPSTF Recommendations: Screening for Primary Open-Angle Glaucoma and Screening for Impaired Visual Acuity in Older Adults

 


Review | Perioperative brain health in the older adult: a patient safety imperative.

24 May, 2022 | 08:03h | UTC

Perioperative Brain Health in the Older Adult: A Patient Safety Imperative – Anesthesia & Analgesia (free for a limited period)

 


M-A: Effect of Sodium-Glucose Cotransporter 2 Inhibitors for heart failure with preserved ejection fraction.

24 May, 2022 | 07:33h | UTC

Effect of Sodium-Glucose Cotransporter 2 Inhibitors for Heart Failure With Preserved Ejection Fraction: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – Frontiers in Cardiovascular Medicine

 


Drugs for agitation in people with dementia: benefits and risks.

23 May, 2022 | 01:25h | UTC

Drugs for agitation in people with dementia: benefits and risks – Evidently Cochrane

Original Study: Antipsychotics for agitation and psychosis in people with Alzheimer’s disease and vascular dementia – Cochrane Library

 

Commentary on Twitter (thread – click for more)

 


Preventing dementia: what’s the evidence?

23 May, 2022 | 01:27h | UTC

Preventing dementia: what’s the evidence? – Evidently Cochrane

 


AHA Scientific Statement: Preventing and managing falls in adults with cardiovascular disease.

20 May, 2022 | 11:20h | UTC

Preventing and Managing Falls in Adults With Cardiovascular Disease: A Scientific Statement From the American Heart Association – Circulation: Cardiovascular Quality and Outcomes

News Release: Statement addresses ways to prevent heart-related risks for falling – American Heart Association

Commentary: AHA News: Falls Can Be a Serious, Poorly Understood Threat to People With Heart Disease – HealthDay

 


Covid-19: Second boosters may benefit at-risk groups but have “minimal” impact for others, says WHO.

20 May, 2022 | 11:08h | UTC

Covid-19: Second boosters may benefit at-risk groups but have “minimal” impact for others, says WHO – The BMJ

Original Statement: Interim statement on the use of additional booster doses of Emergency Use Listed mRNA vaccines against COVID-19 – World Health Organization

Related recommendations:

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines –
European Centre for Disease Prevention and Control

Coronavirus (COVID-19) Update: FDA Authorizes Second Booster Dose of Two COVID-19 Vaccines for Older and Immunocompromised Individuals – U.S. Food & Drug Administration

 


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