Pig genome editing with goal of providing organs for transplant

16Aug
2017

Gene Editing Using CRISPR: Why the Excitement?

15Aug
2017

Genetic counseling works as well over the phone as in person, study finds

15Aug
2017

Gene-edited embryos are exciting, but the truly urgent conversations concern genomic medicine

15Aug
2017

Commit to talks on patient data and public health – Nature News (free)

“unlike gene-edited infants, which are still years away, genomic medicine is with us now” (RT @NatureNews see Tweet)

 

11 Organizations Urge Cautious but Proactive Approach to Gene Editing

11Aug
2017

Simple guide to CRISPR

7Aug
2017

Genetic testing threatens the insurance industry

5Aug
2017

Genetic testing threatens the insurance industry – The Economist (a few articles per month are free)

“Insurers worry about adverse selection; the insured worry about discrimination”

 

Correction of a pathogenic gene mutation in human embryos

3Aug
2017

The genetic background of acromegaly

1Aug
2017

Diagnostic approaches for inherited hemolytic anemia in the genetic era

1Aug
2017

Human Genome Editing: Science, Ethics, and Governance

27Jul
2017

The trouble with genetic testing

23Jul
2017

‘We are all mutants now’: the trouble with genetic testing – The Guardian (free) (RT @EricTopol see Tweet)

Related: The uncertain future of genetic testing – Mosaic (free)

“With so many unknowns in our DNA, using genetics in medical testing doesn’t always bring the answers – sometimes it brings only doubt”.

 

Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome

23Jul
2017

The Uncertain Future of Genetic Testing

21Jul
2017

The Uncertain Future of Genetic Testing – The Atlantic (free)

“Bringing genetics into medicine leads to more accuracy, better diagnosis, and personalized treatment—but for some, gene testing has only resulted in unanswered questions”.

 

Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development

18Jul
2017

Inborn Errors of Metabolism and Epilepsy: Current Understanding, Diagnosis, and Treatment Approaches

18Jul
2017

Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer

17Jul
2017

Clinical practice guidelines for the care of girls and women with Turner syndrome

17Jul
2017

Hereditary pancreatic cancer: related syndromes and clinical perspective

16Jul
2017

Concordance of autoimmune disease in a systemic lupus erythematosus twin cohort

11Jul
2017

Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk

8Aug
2017

Genetic and epigenetic control of gene expression by CRISPR-Cas systems

7Jul
2017

Primary Ciliary Dyskinesia: An Update on Clinical Aspects, Genetics, Diagnosis, and Future Treatment Strategies

7Jul
2017

Single-cell sequencing made simple

4Jul
2017

Single-cell sequencing made simple – Nature News (free)

“Data from thousands of single cells can be tricky to analyse, but software advances are making it easier”.

 

Immunology, one cell at a time

4Jul
2017

Immunology, one cell at a time – Nature News (free)

“Analysing the DNA, RNA and protein of single cells is transforming our understanding of the immune system, say Amir Giladi and Ido Amit”.

 

The Brave New World of Gene Editing

3Jul
2017

The Brave New World of Gene Editing – The New York Review of Books (free)

“In reviewing 3 recent books, @matthewcobb provides exceptional genomics perspective, especially on #CRISPR

 

New Natural Selection: How Scientists are Altering DNA to Genetically Engineer New Forms of Life

30Jun
2017

New Natural Selection: How Scientists are Altering DNA to Genetically Engineer New Forms of Life – Newsweek (Free)

“What happens when you can write and edit genomes? Life 2.0? (RT @EricTopol see Tweet)

 

Precision Medicine: the Promise vs. the Reality

29Jun
2017

Precision Medicine: the Promise vs. the Reality – Michigan University Health Lab (free) (RT @pash22 see Tweet)

“Scientists find great potential in using genetic sequencing to help direct targeted cancer therapy, but practicing oncologists see some important limitations”.

 

The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients

27Jun
2017

Who will pay for CRISPR?

26Jun
2017

New concerns raised over value of genome-wide disease studies

25Jun
2017

New concerns raised over value of genome-wide disease studies – Nature News (free)

“Large analyses dredge up ‘peripheral’ genetic associations that offer little biological insight, researchers say”.

 

What happens when an expensive drug is approved based on a lower bar of proof?

25Jun
2017

Insurers Battle Families Over Costly Drug for Fatal Disease – The New York Times (10 articles per month are free)

“A new drug can cost over a million dollars, even though it’s unclear if it works. Now, insurers are refusing to pay” (RT @NYTHealth see Tweet)

 

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

21Jun
2017

The human genome was never completely sequenced

21Jun
2017

‘Not everyone wants to know': Warnings over genetic tests

20Jun
2017

What If (Almost) Every Gene Affects (Almost) Everything?

19Jun
2017

No Shortcuts on the Long Road to Evidence-Based Genomic Medicine

2Jun
2017

Viewpoint: No Shortcuts on the Long Road to Evidence-Based Genomic Medicine – JAMA (free)

“The need for evidence in genomic medicine is more important than ever” (RT @JAMA_current see Tweet)

 

The Paternal Epigenome Makes Its Mark

6May
2017

Medical News & Perspectives: The Paternal Epigenome Makes Its Mark – JAMA (free)

Related: Influence of paternal preconception exposures on their offspring: through epigenetics to phenotype – American Journal of Stem Cells (free)

“Epigenetic changes may be the underlying mechanism by which paternal factors such as age, diet, weight, stress, and alcohol consumption contribute to a range of health outcomes in offspring including birth defects, behavioral problems, developmental disorders, obesity, diabetes, cardiovascular disease, and cancer”.

 

F.D.A. Will Allow 23andMe to Sell Genetic Tests for Disease Risk to Consumers

10Apr
2017

Genetic assessment of age-associated Alzheimer disease risk

23Mar
2017
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