Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial – The Lancet (free)

Commentaries: CRASH-3: a win for patients with traumatic brain injury – The Lancet (free) AND Global trial is first clear evidence that a widely available drug reduces head injury deaths – London School of Hygiene & Tropical Medicine (free) AND PulmCrit- Tranexamic acid for traumatic brain injury (CRASH3) (free) AND CRASH-3! – Emergency Medicine Literature of Note (free) AND Head injuries: Cheap drug ‘could save thousands of lives a year’ – BBC (free) AND Common drug could prevent thousands of head injury deaths – The Guardian (free)

Related: Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds? (free resources on the subject)

Italian guidelines for the surgical management of enteral stomas in adults – Techniques in Coloproctology (free)

Lead toxicity from retained bullet fragments: A systematic review and meta-analysis – Journal of Trauma and Acute Care Surgery (link to abstract – $ for full-text)

Commentary: Are Bullet Fragments Causing Lead Poisoning? – Journal Feed (free)

Oxygen toxicity in major emergency surgery—anything new? – Intensive Care Medicine (free)

Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND WHO Guidelines for Peri-Operative Hyperoxia Questioned (free) AND The Association Between Supra-Physiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients: A Multi-Centre Observational Cohort Study – American Journal of Respiratory and Critical Care Medicine (free) AND Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit: The Oxygen-ICU Randomized Clinical Trial – JAMA (free)

Colonoscopy Adverse Events – NEJM Journal Watch (free)

Original Article: ASGE review of adverse events in colonoscopy – GIE Gastrointestinal Endoscopy (link to abstract – $ for full-text)

Blast injuries in children: a mixed-methods narrative review – BMJ Paediatrics Open (free)

Cool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns: A Cohort Study of Two Thousand Four Hundred Ninety-five Children – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Simple Cool Running Water Reduces Burn Severity in Children – Journal Feed (free)

Understanding acute burn injury as a chronic disease – Burns & Trauma (free)

Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture – New England Journal of Medicine (free)

Commentary: International study finds similar results from total or partial hip replacement – McMaster University (free)

Helmet use and bicycle-related trauma injury outcomes – Brain Injury (free)

Commentary: More evidence supports helmet use by cyclists – Reuters (free) AND Most cyclists suffering head injuries not wearing helmets, study shows – HealthDay (free)

Head injury: assessment and early management – National Institute for Health and Care Excellence (free)

Related Guidelines: Management of severe traumatic brain injury (first 24 hours) – Anaesthesia Critical Care & Pain Medicine (free) AND New Guidelines for the Management of Pediatric Severe Traumatic Brain Injury (free) AND CDC Guideline: Diagnosis and Management of Mild Traumatic Brain Injury Among Children (free) AND Italian guidelines on the assessment and management of pediatric head injury in the emergency department – Italian Journal of Pediatrics (free) AND Scandinavian guidelines for initial management of minor and moderate head trauma in children – BMC Medicine (free)

Effect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentaries: Vasopressin as an Early Adjunct to Resuscitation in Hemorrhagic Shock: Crisis AVERTed? – JAMA Surgery (free) AND Giving trauma patients blood pressure stabilizing hormone cuts transfusions by half – University of Pennsylvania School of Medicine (free)

Author Interview: Arginine Vasopressin Supplementation in Early Traumatic Shock (free)

“Additional research is necessary to determine whether including AVP improves morbidity or mortality.”

Cervical Spine Injury Risk Factors in Children With Blunt Trauma – Pediatrics (link to abstract – $ for full-text)

Commentary: Screening for cervical spine risk factors could reduce CT scans by half – Nationwide Children’s Hospital (free)

New clinical guidelines on the spinal stabilisation of adult trauma patients – consensus and evidence based – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

Related: The Norwegian guidelines for the prehospital management of adult trauma patients with potential spinal injury (free) AND Cervical spine collar clearance in the obtunded adult blunt trauma patient: A systematic review and practice management guideline from the Eastern Association for the Surgery of Trauma (free) AND Prehospital Cervical Spinal Immobilization After Trauma – Neurosurgery (free) AND Pre-Hospital Care Management of a Potential Spinal Cord Injured Patient: A Systematic Review of the Literature and Evidence-Based Guidelines – Journal of Neurotrauma (free) AND Wilderness Medical Society Practice Guidelines for Spine Immobilization in the Austere Environment (free)

Risk, Prevention, Diagnosis, and Management of Post-Operative Cutaneous Infection – Current Dermatology Reports (free)

Related: Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free) AND Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery(free) AND Global guidelines on the prevention of surgical site infection – World Health Organization

Imaging in Suspected Renal Colic: Systematic Review of the Literature and Multispecialty Consensus – Annals of Emergency Medicine (free)

Diagnostic Imaging in Pregnant Patients With Suspected Appendicitis – JAMA (free for a limited period)

Management of Severe Bleeding in Patients Treated With Oral Anticoagulants – Critical Pathways in Cardiology (free)

Related: 2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants (free guideline and summary)

Hartmann’s procedure versus sigmoidectomy with primary anastomosis for perforated diverticulitis with purulent or faecal peritonitis (LADIES): a multicentre, parallel-group, randomised, open-label, superiority trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Farewell to Hartmann’s Procedure? – MedPage Today (free registration required)

Related Commentary on Twitter

Hartmann’s procedure versus sigmoidectomy with primary anastomosis for perforated #diverticulitis with purulent or faecal peritonitis (LADIES): a randomised trial – https://t.co/nhWBkVvIxS #colorectalresearch #colorectalsurgery #SoMe4Surgery pic.twitter.com/oGGrgEg13T

— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 7, 2019

Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free)

A Multicenter Trial of Vena Cava Filters in Severely Injured Patients – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Liberal IVC Filter Use Not Warranted in Severe Trauma Patients – TCTMD (free)

Related Commentary on Twitter

Early prophylactic placement of a vena cava filter after major trauma does not result in a lower incidence of symptomatic pulmonary embolism or death at 90 days than no placement of a filter. #ISTH2019 https://t.co/ZjMqDcaOL5 pic.twitter.com/7jXvYAW5hx

— NEJM (@NEJM) July 8, 2019

Association of Coworker Reports About Unprofessional Behavior by Surgeons With Surgical Complications in Their Patients – JAMA Surgery (free for a limited period)

Commentaries: When Surgeons Are Abrasive To Co-Workers, Patients’ Health May Suffer – NPR (free) AND Unprofessional Behavior by Surgeons Linked to Surgical Complications in Their Patients – MedicalResearch.com (free) AND After surgery, how patients fare may depend on how their doctor behaves, study says – CNN (free)

Negative Pressure Wound Therapy for Surgical-site Infections: A Randomized Trial – Annals of Surgery (link to abstract – $ for full-text)

Related Cochrane Review: Negative pressure wound therapy for surgical wounds healing by primary closure (free)

Source: EvidenceAlerts

Related Commentary on Twitter

A new RCT from @HopkinsMedicine shows that incisional wound vacs can decrease wound infections in high-risk patients after pancreaticoduodenectomy: https://t.co/qlgCg7wfRB
by @ammarjaved @MartyMakary @surgeonweiss et al #VisualAbstract pic.twitter.com/Tlq1RzGh1w

— Annals of Surgery (@AnnalsofSurgery) December 5, 2018

Does Atelectasis Cause Fever After Surgery? Putting a Damper on Dogma – JAMA Surgery (free for a limited period)

Idiopathic acute pancreatitis: a review on etiology and diagnostic work-up – Clinical Journal of Gastroenterology (free)

Transition Planning for the Senior Surgeon: Guidance and Recommendations From the Society of Surgical Chairs – JAMA Surgery (free for a limited period)

Invited Commentary: Planning for Retiring From Operating (free for a limited period)

Author Interview: Transition Planning for the Senior Surgeon (free audio)

Bowel obstruction: a narrative review for all physicians – World Journal of Emergency Surgery (free)

Surgical management of multiple rib fractures/flail chest – Journal of Thoracic Disease (free)

Source: Critical Care Reviews Newsletter

Association of Statewide Implementation of the Prehospital Traumatic Brain Injury Treatment Guidelines With Patient Survival Following Traumatic Brain Injury: The Excellence in Prehospital Injury Care (EPIC) Study – JAMA Surgery (free for a limited period)

Commentary: Revised guidelines improve survival rates for traumatic brain injury patients – UPI (free)

American Association for the Surgery of Trauma emergency general surgery guideline summaries 2018: acute appendicitis, acute cholecystitis, acute diverticulitis, acute pancreatitis, and small bowel obstruction – Trauma Surgery & Acute Care Open (free)

Diagnostic Modalities for Acute Compartment Syndrome of the Extremities: A Systematic Review – JAMA Surgery (free for a limited period)

Management of acute abdomen in pregnancy: current perspectives – International Journal of Women’s Health (free)

Management of moderate and severe traumatic brain injury – Transfusion (free)

Association of Duration and Type of Surgical Prophylaxis With Antimicrobial-Associated Adverse Events – JAMA Surgery (free for a limited period)

Commentaries: Balancing the Risks and Benefits of Surgical Prophylaxis: Timing and Duration Do Matter – JAMA Surgery (free for a limited period) AND Longer Antibiotic Rx After Surgery Tied to Increasing Harms, Limited Benefits – NEJM Journal Watch (free)

Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free)

Related Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) AND Global guidelines on the prevention of surgical site infection – World Health Organization (free) AND Infection prevention in the operating room anesthesia work area – Infection Control & Hospital Epidemiology (free)

The 2018 Lebanese Society of Infectious Diseases and Clinical Microbiology Guidelines for the use of antimicrobial therapy in complicated intra-abdominal infections in the era of antimicrobial resistance – BMC Infectious Diseases (free)

Related Guidelines: The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines – World Journal of Emergency Surgery (free) AND The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections (free)

S2k guidelines for skin and soft tissue infections Excerpts from the S2k guidelines for “calculated initial parenteral treatment of bacterial infections in adults – update 2018“ (free)

Related Guidelines: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free text and infographics) AND Clinical Guidelines for the Antibiotic Treatment for Community-Acquired Skin and Soft Tissue Infection – Korean Society of Infectious Diseases and Korean Society for Chemotherapy (free) AND 2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections – World Journal of Emergency Surgery (free)

The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition – Critical Care (free)

Imaging in trauma in limited-resource settings: A literature review – African Journal of Emergency Medicine (free)

Whole Blood in Trauma: Ready for Primetime? – emDocs (free)

Related: Limitations of component therapy for massive haemorrhage: is whole blood the whole solution? – Anaesthesia (free)

Management of male pelvic fracture urethral injuries: Review and current topics – International Journal of Urology (free)

Use of prophylactic antibiotic in preventing complications for blunt and penetrating chest trauma requiring chest drain insertion: a systematic review and meta-analysis – Trauma Surgery & Acute Care Open (free)

Evaluation of the Collaborative Use of an Evidence-Based Care Bundle in Emergency Laparotomy – JAMA Surgery (free)

Related Commentary on Twitter

A collaborative approach using a quality improvement methodology and a care bundle appeared to be effective in reducing mortality and length of stay in emergency laparotomy. https://t.co/tr0esQxdWC

— JAMA Surgery (@JAMASurgery) March 22, 2019

Safe Use of Surgical Staplers and Staples – Letter to Health Care Providers – U.S Food & Drug Administration (free)

Commentary: FDA Alerts Clinicians About Surgical Staple Risks – NEJM Journal Watch (free)

Related: Hidden FDA Reports Detail Harm Caused By Scores Of Medical Devices – Kaiser Health News (free)

Enhanced recovery after surgery in emergency colorectal surgery: Review of literature and current practices – World Journal of Gastrointestinal Surgery (free)

Related Guidelines: Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons (free) AND Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS^®) Society Recommendations: 2018 (free)

An ultrasound scan is not as useful as a CT scan in assessing trauma – NIHR Signal (free)

Original Article: Point‐of‐care ultrasonography for diagnosing thoracoabdominal injuries in patients with blunt trauma – Cochrane Library (free)

2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients – World Journal of Emergency Surgery (free)

Related Guidelines: IDSA Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children (free) AND The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications (free) AND Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients (free) AND Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children (free)

Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines (free)

Commentary: Traumatic brain injury and kids: New treatment guidelines issued – Oregon Health & Science University (free)

Initial Management of Thoracic Traumas – Journal of Thoracic Disease (free articles)

Homepage

Pulmonary contusion

Diaphragm and transdiaphragmatic injuries

Thoracic damage control surgery

Blast injures to the thorax

Management of traumatic esophageal injuries

Surgical management of chronic diaphragmatic hernias

Chest drain and thoracotomy for chest trauma

First-Line Diagnostic Evaluation with MRI of Children Suspected of Having Acute Appendicitis – Radiology (link to abstract – $ for full-text)

Commentary: MRI an effective first step for imaging young patients with suspected acute appendicitis – Radiology Business (free)

Risks and benefits of hypotensive resuscitation in patients with traumatic hemorrhagic shock: a meta-analysis – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

Commentary: Permissive hypotensive resuscitation in patients with traumatic hemorrhagic shock – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

Association of Surgical Intervention for Adhesive Small-Bowel Obstruction With the Risk of Recurrence – JAMA Surgery (link to abstract – $ for full-text)

Commentaries: Quick Take: Association of Surgical Intervention for Adhesive Small-Bowel Obstruction With the Risk of Recurrence – 2 Minute Medicine (free) AND Surgery Best for First Adhesive Small Bowel Obstruction – MedPage Today (free registration required)

Related Commentary on Twitter

Association of surgery for adhesive small-bowel obstruction with the risk of recurrence https://t.co/uiEzX5JHOw #VisualAbstract pic.twitter.com/6noy5k57eC

— JAMA Surgery (@JAMASurgery) January 30, 2019

Best practice advice on pre-hospital emergency anaesthesia & advanced airway management – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

American Medical Society for Sports Medicine position statement on concussion in sport – British Journal of Sports Medicine (free)

Related Guidelines: Consensus statement on concussion in sport—the 5^th international conference on concussion in sport held in Berlin, October 2016 – British Journal of Sports Medicine (free) AND Implementation of the 2017 Berlin Concussion in Sport Group Consensus Statement in contact and collision sports: a joint position statement from 11 national and international sports organisations – British Journal of Sports Medicine (free) AND Clinical Report: Sport-Related Concussion in Children and Adolescents – Pediatrics (free)

Early Subthreshold Aerobic Exercise for Sport-Related Concussion: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: For Teens with Concussion, Moderate Aerobic Activity Can Shorten the Time to Recovery – NEJM Journal Watch (free) AND Concussion treatment: Adolescent athletes ‘prescribed’ aerobic exercise recovered faster – University at Buffalo (free)

Sports-related concussions are bad, but kids who participate in appropriate aerobic exercise after them recover faster than those who do not! New research in @JAMAPediatrics https://t.co/EPHdqWqbbg #kids #concussions #headinjury #pediatrics #trauma pic.twitter.com/f3m1ApeNPH

— JAMA Pediatrics (@JAMAPediatrics) February 5, 2019

Rectal Foreign Bodies: Not always a Simple ED Diagnosis – emDocs (free)

When Is the Surgeon Too Old to Operate? – The New York Times (free)

Related: Perspective: Assessing the Performance of Aging Surgeons (free for a limited period) AND Observational Study: Age and Sex of Surgeons and Mortality of Older Surgical Patients (free study and commentary) AND The Elderly and Driving: When Is It Time to Hit the Brakes? – The New York Times (10 articles per month are free)

Related Commentary on Twitter

Interesting and provocative issue. We have a generation of baby boomer surgeons for whom being a surgeon became their primary identity and therefore extremely difficult for them to walk away from. https://t.co/UVYLPzLv6m

— T. Sloane Guy, MD, MBA (@sloaneguy) February 2, 2019

Early cooling provides no benefit following traumatic brain injury – NIHR Signal (free)

Original Study: Prophylactic Hypothermia Questioned After Severe Traumatic Brain Injury (link to abstract and commentary)

Fatal flaws in clinical decision making – ANZ Journal of Surgery (free)

Commentary: Fatal flaws in clinical decision making – PSNet (free)

Missed injuries in trauma patients – an Emergency Medicine Perspective – emDocs (free)

Related Review: Missed traumatic injuries: A synopsis – International Journal of Academic Medicine (free)

Management of Acute Compartment Syndrome – American Academy of Orthopaedic Surgeons (free PDF)

News Release: American Academy of Orthopaedic Surgeons approves clinical practice guideline for management of acute compartment syndrome (free)

BJS Special Issue on Global Surgery (supplement with free articles)

Homepage

Related Commentary on Twitter

🌍🥁🎉📣We are absolutely delighted to announce the BJS 2019 Special Issue on #GlobalSurgery is now live! It is entirely free to access and we hope you find it a fascinating read. Look out for lots of tweets highlighting what's included. https://t.co/h3lClGUf4b pic.twitter.com/qg3rw71OvU

— BJS (@BJSurgery) January 8, 2019

Selected articles from the supplement:

– Global surgery in an ecosystem for worldwide health

– Ethical considerations in global surgery

– Implementation science and innovation in global surgery

– A realized vision of access to safe, affordable surgical and anaesthesia care

– Training and accrediting international surgeons

– Disseminating technology in global surgery

– Global surgery and the sustainable development goals

– Systematic review of the use of big data to improve surgery in low‐ and middle‐income countries

– Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy

Assessing the Performance of Aging Surgeons – JAMA (free for a limited period)

Early management of severe pelvic injury (first 24 hours) – Anaesthesia Critical Care & Pain Medicine (free)

Antibiotic use in patients with abdominal injuries: guideline by the Korean Society of Acute Care Surgery – Annals of Surgical Treatment and Research (free)

Point‐of‐care ultrasonography for diagnosing thoracoabdominal injuries in patients with blunt trauma – Cochrane Library (free)

Summary: How accurate is bedside ultrasound for the diagnosis of injuries to the abdomen or chest in patients with blunt injuries? – Cochrane Library (free)

Imaging and Endovascular Treatment of Bleeding Pelvic Fractures: Review Article – Cardiovascular and Interventional Radiology (free)

Preventing surgical site infections: implementation approaches for evidence-based recommendations – World Health Organization (free PDF) (via @onisillos)

Ultrarestrictive Opioid Prescription Protocol for Pain Management After Gynecologic and Abdominal Surgery – JAMA Network Open (free)

Commentaries: Striving for Evidence-Based Postoperative Opioid Prescribing While Optimizing Perioperative Pain Management—Shifting to Conservative Prescribing – JAMA Network Open (free) AND Opioid Prescriptions Can Be Drastically Reduced After Surgery with No Increase in Pain, Study Shows – Roswell Park (free)

Prevalence of and Factors Associated With Patient Nondisclosure of Medically Relevant Information to Clinicians – JAMA Network Open (free)

Commentaries: Threats to the Validity of the Clinical Interview: Can Anything Be Done? – JAMA Network Open (free) AND Patients often withhold relevant information from doctors – Reuters (free) AND Most Patients Have Held Back the Truth From Doctors, JAMA Results Show – AJMC (free) AND Why patients lie to their doctors – University of Utah Health (free) AND Majority of Patients Withhold Important Information From Their Health Care Providers – MedicalResearch.com (free)

The Current Status of Decompressive Craniectomy in Traumatic Brain Injury – Current Trauma Reports (free)

Endoscopic Drainage of Pancreatic Fluid Collections – Clinical Gastroenterology and Hepatology (free)

Whole body computed tomography in multi trauma patients: Review of the current literature – Turkish Journal of Emergency Medicine (free)

Nasointestinal tubes versus nasogastric tubes in the management of small-bowel obstruction: A meta-analysis – Medicine (free)

The Effectiveness of Antiepileptic Medications as Prophylaxis of Early Seizure in Traumatic Brain Injury Patients Compared to Placebo or No Treatment: A Systematic Review and Meta-Analysis – World Neurosurgery (link to abstract – $ for full-text)

Commentary: Early seizure prophylaxis with antiepileptics in TBI has only modest effects – Univadis (free registration required)

Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 – The Lancet Neurology (free)

Invited commentary: Global burden of traumatic brain and spinal cord injury (free)

Surgical Value — Beyond Bundled Payments – NEJM Catalyst (free)

Best practice guidelines for blunt cerebrovascular injury (BCVI) – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

Level 3 guideline on the treatment of patients with severe/multiple injuries – German Trauma Society (free)

News Release: The updated German “Polytrauma – Guideline”: an extensive literature evaluation and treatment recommendation for the care of the critically injured patient (free)

Source: Critical Care Reviews Newsletter

Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial – The BMJ (free)

“Laparoscopic cholecystectomy compared with percutaneous catheter drainage reduced the rate of major complications in high risk patients with acute cholecystitis.”

Two‐year results of the randomized clinical trial DILALA comparing laparoscopic lavage with resection as treatment for perforated diverticulitis – British Journal of Surgery (free)

Commentary: Comparing Laparoscopic Lavage vs Resection for Perforated Diverticulitis – Medscape (free registration required)

Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Podcast: Treating Appendicitis Without Surgery – 5-Year Follow-up from a Randomized Clinical Trial of Antibiotic Treatment (free)

Video Summary: Five-Year Follow-up of Patients Given Antibiotic Therapy for Uncomplicated Acute Appendicitis (free)

Commentaries: Pills for appendicitis? Surgery often not needed, study says – STAT (free) AND Antibiotics Alone Seem Reasonable for Uncomplicated Appendicitis in Adults – Physician’s First Watch (free) AND Appendicitis? Antibiotics May Be All You Need – The New York Times (10 articles per month are free)

Related: Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis (link to abstract and commentaries) AND Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (link to abstract and commentaries) AND Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis (free study and commentaries) AND New appendicitis guideline incorporates the possibility of non-operative treatment for uncomplicated disease (free guideline)

Management of Chronic Wounds—2018 – JAMA (free for a limited period)

Infant Walker–Related Injuries in the United States – Pediatrics (free)

News Release: Study: Infant walker injuries support AAP’s call for a ban (free)

Commentaries: As Injuries Continue, Doctors Renew Call For Ban On Infant Walkers – NPR (free) AND Injuries associated with infant walkers still sending children to the emergency department – Nationwide Children’s Hospital (free)

Pancreatitis – National Institute for Health and Care Excellence (free)

Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild Traumatic Brain Injury Among Children – JAMA Pediatrics (free)

Commentaries: CDC releases updated guideline on diagnosis and management of pediatric mTBI – Kennedy Krieger Institute, via EurekAlert (free) AND CDC Seeks to Standardize Mild TBI Management in Kids – MedPage Today (free registration required) AND New advice on kids’ concussions calls for better tracking – Associated Press (free) AND CDC issues first guidelines to treat youth concussions – CNN (free)

2018 Korean Clinical Imaging Guideline for Hemoptysis – Korean Journal of Radiology (free)

Strategy of endovascular versus open repair for patients with clinical diagnosis of ruptured abdominal aortic aneurysm: the IMPROVE RCT – Health Technology Assessment (free)

Commentary: Endovascular aortic repair (EVAR) surgery more beneficial for ruptured abdominal aortic aneurysms than open repair – NIHR Signal (free)

Strategy of endovascular versus open repair for patients with clinical diagnosis of ruptured abdominal aortic aneurysm: the IMPROVE RCT – Health Technology Assessment (free)

Commentary: Endovascular aortic repair (EVAR) surgery more beneficial for ruptured abdominal aortic aneurysms than open repair – NIHR Signal (free)

A systematic review on the use of topical hemostats in trauma and emergency surgery – BMC Surgery (free)

Imaging in trauma in limited-resource settings: A literature review – African Journal of Emergency Medicine (free)

Source: Critical Care Reviews Newsletter

2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation – World Journal of Emergency Surgery (free)

Management of Groin Hernias in Adults—2018 – JAMA (free for a limited period)

Association Between Traumatic Brain Injury and Risk of Suicide – JAMA (link to abstract – $ for full-text)

Commentaries: Traumatic brain injury tied to increased risk of suicide – Reuters (free) AND Risk of Suicide Increases After TBI, Study Finds – Psychiatric News Alert (free) AND Expert reaction to traumatic brain injury and suicide – Science Media Centre (free)

Mortality effects of timing alternatives for hip fracture surgery – Canadian Medical Association Journal (free)

Commentaries: Lower death rate when senior hip fractures are repaired quickly – Reuters (free) AND Delayed surgery for hip fractures cause of preventable deaths, study finds – The Globe and Mail (free) AND The sun should not set twice before hip fracture repair – CMAJ, via ScienceDaily (free)

The use of viscoelastic haemostatic assays in the management of major bleeding: A British Society for Haematology Guideline – British Journal of Haematology (free)

Source: Critical Care Reviews Newsletter

Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Giving Plasma to Trauma Patients with Severe Bleeding During Air Transport Saves Lives – Health Sciences at the University of Pittsburgh, via NewsWise (free)

Richard Smith: Reducing global road traffic crashes and injuries – The BMJ Opinion (free)

Related reports: The High Toll of Traffic Injuries : Unacceptable and Preventable – The World Bank (free PDF) AND Save LIVES: a road safety technical package (free) AND Unfinished Journey: The Global Health Response to Children & Road Traffic – FIA Foundation (free PDF) AND Securing safe roads: the politics of change – World Resources Institute Ross Center for Sustainable Cities (free news release and PDF)

Negative pressure wound therapy for open traumatic wounds – Cochrane Library (free)

Summary: Negative pressure wound therapy for open traumatic wounds – Cochrane Library (free)

Related Research: Randomized Trial: Negative Pressure Wound Therapy No Better Than Regular Dressing in Severe Open Fracture of the Lower Limb (link to abstract and commentaries)

A visual summary of the trauma call timeline – The BMJ (free PDF)

Mesh repair of small umbilical hernias reduces recurrence compared to sutures – NIHR Signal (free)

Original Article: Mesh versus suture repair of umbilical hernia in adults: a randomised, double-blind, controlled, multicentre trial – The Lancet (link to abstract – $ for full-text)

Risk stratification tools in emergency general surgery – Trauma Surgery and Acute Care Open (free)

Source: Critical Care Reviews Newsletter

Orthopaedic traumatology: fundamental principles and current controversies for the acute care surgeon – Trauma Surgery and Acute Care Open (free)

Source: Critical Care Reviews Newsletter

Joint statement from the American College of Surgeons Committee on Trauma (ACS COT) and the American College of Emergency Physicians (ACEP) regarding the clinical use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) (free)

Commentary: EMCrit Guest Post – The good, the bad, and the ugly of the Joint Statement on REBOA by Zaffer Qasim (free)

Source: Critical Care Reviews Newsletter

Association of Preprocedural Fasting With Outcomes of Emergency Department Sedation in Children – JAMA Pediatrics (free for a limited period)

Commentaries: Preprocedural Fasting Not Necessary for Children in ED – Medscape (free registration required) AND Pre-Sedation Guidelines for Kids May Be Too Strict – MedPage Today (free registration required)

Related: NPO for sedation? Don’t swallow the myth – First10Em (free)

The Chest Bump: Pulmonary Pearls & Pitfalls to Consider in Patients with Chest Trauma – emDocs (free)

Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018 – Gut (free)

Source: Critical Care Reviews Newsletter

Meta‐analysis evaluating music interventions for anxiety and pain in surgery – British Journal of Surgery (free)

Commentary: Soothing sounds: Music reduces patient anxiety, pain during surgery – Clinical Innovation and Technology (free)

Age and sex of surgeons and mortality of older surgical patients: observational study – The BMJ (free)

Editorial: Links between age and sex of surgeons and patients’ outcomes (free)

Commentary: Study Suggests Older Surgeons Produce Lower Mortality Rates in Emergency Procedures – UCLA, via NewsWise (free)

Simplifying the use of prognostic information in traumatic brain injury – Journal of Neurosurgery

Part 1: The GCS-Pupils score: an extended index of clinical severity (free)

Part 2: Graphical presentation of probabilities (free)

Commentaries: New Glasgow Coma Scale–Pupils Score and Multifactor Probability Outcome Charts for Use in Patients with TBI – Journal of Neurosurgery, via NewsWise (free) AND New scoring system will speed up assessment of brain injuries – OnMedica (free) AND Glasgow Coma Scale Gets an Eye-Opening Update – Medscape (free registration required)

Lower extremity traumatic amputations—brief review of reconstruction, wound and soft tissue management, alternatives to conventional practice – Journal of Emergency and Critical Care Medicine (free)

Source: Critical Care Reviews Newsletter

Pancreatitis: Pearls & Pitfalls – emDocs (free)

Related guidelines: American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis – Gastroenterology (free) AND Clinical practice guideline: management of acute pancreatitis – Canadian Journal of Surgery (free)

Plasma metabolomic biomarkers accurately classify acute mild traumatic brain injury from controls – PLOS One (free)

Commentary: Blood biomarkers may allow easier detection, confirmation of concussions – University of California, Irvine, via EurekAlert (free)

Pediatric Minor Head Injury 2.0: Moving from Injury Exclusion to Risk Stratification – Emergency Medicine Clinics of North America (free)

Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis – Annals of Emergency Medicine (free)

Commentary: Meta-Analysis Favors Antibiotics After Drainage of Skin Abscesses – NEJM Journal Watch (free)

See related guideline with infographic: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free) AND Meta-Analysis: Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis – BMJ Open (free)

Effective interventions for unintentional injuries: a systematic review and mortality impact assessment among the poorest billion – The Lancet Global Health (free)

Long-term risk of dementia among people with traumatic brain injury in Denmark: a population-based observational cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentaries: Study confirms link between traumatic brain injury and dementia – UW Medicine, via EurekAlert (free) AND Traumatic brain injury increases risk of dementia – OnMedica (free) AND Brain injury may increase dementia risk – NHS Choices (free)

Related articles: Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study – PLOS One (free) AND Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football – JAMA (free)

Association of Whole-Body Computed Tomography With Mortality Risk in Children With Blunt Trauma – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: Whole-Body CT Scans Don’t Appear to Improve Survival in Kids with Blunt Trauma – NEJM Physician’s First Watch (free) AND CT Pan-Scan: No Mortality Benefit in Kids With Blunt Trauma – Medscape (free registration required) AND Whole body CT doesn’t cut mortality in peds blunt trauma – MedicalXpress (free)

Report: Securing safe roads: the politics of change – World Resources Institute Ross Center for Sustainable Cities (free news release and PDF)

Commentary: Death Toll On World’s Roads Grows, But Not Will To Stop It, New Report Finds – Forbes (free)

Related World Bank Report: The High Toll of Traffic Injuries : Unacceptable and Preventable – The World Bank (free PDF)

Related WHO Report: Save LIVES: a road safety technical package (free)

Source: International Health Policies Newsletter (free PDF)

Cost-effectiveness of Magnetic Resonance Imaging in Cervical Clearance of Obtunded Blunt Trauma After a Normal Computed Tomographic Finding – JAMA Surgery (link to abstract – $ for full-text)

Commentaries: Neck injury follow-up MRI may cost patients thousands in unnecessary exams – HealthImaging (free) AND No Benefit for MRI After Normal Cervical CT in Blunt Trauma – Physician’s Briefing (free)

Venous Thromboembolism Prevention in Emergency General Surgery: A Review – JAMA Surgery (free for a limited period)

Commentary: VTE Risk Up in Most Emergency General Surgery Patients – Physician’s Weekly (free)

Pediatric Hoverboard and Skateboard Injuries – Pediatrics (free)

Commentaries: More Than 26,000 Children Treated for Hoverboard Injuries in 2015-2016 – American Academy of Pediatrics (free) AND Hoverboards Tied to Nearly 27,000 Pediatric Injuries in First 2 Years on Market – NEJM Physician’s First Watch (free)

Secondary Attention-Deficit/Hyperactivity Disorder in Children and Adolescents 5 to 10 Years After Traumatic Brain Injury – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: Traumatic Brain Injury Tied to Later ADHD in Kids – NEJM Physician’s First Watch (free) AND Childhood Brain Injuries May be Linked to ADHD Years Later – MedPage Today (free registration required) AND TBI Predisposes Kids To Attention Deficit Problems, Even Years After Injury – MedicalResearch.com (free)

Mesh versus suture repair of umbilical hernia in adults: a randomised, double-blind, controlled, multicentre trial – The Lancet (link to abstract – $ for full-text)

Prevention of Incisional Hernias after Open Abdomen Treatment – Frontiers in Surgery (free)

Management of Multi-Casualty Incidents in Mountain Rescue: Evidence-Based Guidelines of the International Commission for Mountain Emergency Medicine (ICAR MEDCOM) (free)

Source: Critical Care Reviews Newsletter

Hemorrhagic Shock: Pearls and Pitfalls for the Resuscitation Room – emDocs (free)

Contemporary Strategies in the Management of Civilian Abdominal Vascular Trauma – Frontiers in Surgery (free)

Source: Critical Care Reviews Newsletter

Implementation of the 2017 Berlin Concussion in Sport Group Consensus Statement in contact and collision sports: a joint position statement from 11 national and international sports organisations – British Journal of Sports Medicine (free)

Management of traumatic brain injury patients – Synapse (free)

Source: Critical Care Reviews Newsletter

Guidelines for Burn Care Under Austere Conditions: Surgical and Nonsurgical Wound Management – Journal of Burn Care & Research (free)

See also: Guideline for Burn Care Under Austere Conditions: Special Care Topics (free)

Source: Critical Care Reviews Newsletter

Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How? – Frontiers in Endocrinology (free)

Incidence of Delayed Intracranial Hemorrhage in Older Patients After Blunt Head Trauma – JAMA Surgery (link to abstract – $ for full-text)

Source: Repeat Head CT or Admission for Delayed Head Bleed Is Wasteful – NEJM Journal Watch ($)

Are you ready for the ATLS 10th Edition Updates? – emDocs (free)

Related: Infographic: ATLS Trauma Update 2018

FDA authorizes marketing of first blood test to aid in the evaluation of concussion in adults – FDA News Release (free)

Commentary: FDA approves first blood test to aid in diagnosis of concussions – STAT (free)

Pediatric traumatic brain injury – Journal of Emergency and Critical Care Medicine (free)

Source: Critical Care Reviews Newsletter

Infographic: ATLS Trauma Update 2018 (free) (via @CritCareReviews)

Tranexamic acid reduces blood loss in intertrochanteric fractures: A meta-analysis from randomized controlled trials – Medicine (free)

Rapid Recommendations: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free text and infographics)

Early use of tranexamic acid reduces bleeding more effectively – NIHR Signal (free)

Original article: Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free) AND Invited Commentary: Tranexamic acid: is it about time? (free)

“It is now clearer that every 15-minute delay after the first hour can reduce survival by about 10%”.

Comprehensive Review of Skiing and Snowboarding Injuries – Journal of the American Academy of Orthopaedic Surgeons, via Medscape (free)

WSES guidelines for the management of iatrogenic colonoscopy perforation – World Journal of Emergency Surgery (free)

Weekend Surgical Care and Postoperative Mortality: A Systematic Review and Meta-Analysis of Cohort Studies (free)

Commentary: Evidence Supports ‘Weekend Effect’ for Mortality after Surgery – Wolters Kluwer, via NewsWise (free)

“The odds of postoperative mortality were 27 percent higher for patients admitted to the hospital on Saturday or Sunday, compared to those hospitalized on a weekday” (from NewsWise).

Italian guidelines on the assessment and management of pediatric head injury in the emergency department – Italian Journal of Pediatrics (free)

Beta-Blockers and Traumatic Brain Injury: A Systematic Review, Meta-Analysis, and Eastern Association for the Surgery of Trauma Guideline – Annals of Surgery, via Medscape (free registration required)

Intraabdominal Hypertension, Abdominal Compartment Syndrome, and the Open Abdomen – Chest (free)

Source: Critical Care Reviews Newsletter

Chemical venous thromboembolism prophylaxis in neurosurgical patients: an updated systematic review and meta-analysis – Journal of Neurosurgery (link to abstract – $ for full-text)

Chemical venous thromboembolism prophylaxis seems to be effective and safe in neurosurgical patients.

Source: EvidenceAlerts

Acute respiratory distress syndrome in traumatic brain injury: how do we manage it? – Journal of Thoracic Disease (free)

Damage Control for Vascular Trauma from the Prehospital to the Operating Room Setting – Frontiers in Surgery (free)

Report: The High Toll of Traffic Injuries : Unacceptable and Preventable – The World Bank (free PDF) (via @equitylist)

Press release: Road Deaths and Injuries Hold Back Economic Growth in Developing Countries (free)

Key Findings: The High Toll of Traffic Injuries : Unacceptable and Preventable – The World Bank (free)

European Hernia Society guidelines on prevention and treatment of parastomal hernias – Hernia (free) (checar acesso)

Prevalence of Work-Related Musculoskeletal Disorders Among Surgeons and Interventionalists: A Systematic Review and Meta-analysis – JAMA Surgery (free)

Author Interview: Work-Related Musculoskeletal Disorders Among Surgeons and Interventionalists (free)

Commentary: Work-Related Musculoskeletal Injury Common in Surgeons, Interventionalists – Medscape (free registration required)

Management of perceived devastating brain injury after hospital admission: a consensus statement from stakeholder professional organizations – British Journal of Anaesthesia (free)

Source: Critical Care Reviews Newsletter

A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway – Surgical Infections (free)

Variceal Bleeding: Update of Recommendations From The Brazilian Association of Hepatology – Arquivos de Gastroenterologia (free)

Users’ guide to the surgical literature: how to assess a noninferiority trial – Canadian Journal of Surgery (free)

Traumatic coagulopathy and massive transfusion: improving outcomes and saving blood – NIHR Journals Library (free)

Traumatic Cerebrospinal Fluid Leak: Diagnosis and Management – Korean Journal of Neurotrauma (free)

Le Fort Fractures: A Collective Review – Bulletin of Emergency and Trauma (free)

Antithrombotics in trauma: management strategies in the older patients – Journal of Blood Medicine (free)

Association Between Wait Time and 30-Day Mortality in Adults Undergoing Hip Fracture Surgery – JAMA (link to abstract – $ for full-text)

Commentaries: Delaying Surgery for Hip Fracture for More Than One Day Associated with Small Increased Risk of Death – The JAMA Network (free) AND Delaying Hip Fracture Surgery for 1 Day Tied to Higher Mortality Risk – Physician’s First Watch (free) AND Emergency Hip Surgery Best Done Within 24 Hours – Medscape (free registration required)

Role for laparoscopy in the management of bile duct injuries – Canadian Journal of Surgery (free)

Laparoscopic splenectomy: Current concepts – World Journal of Gastrointestinal Endoscopy (free)

Direct medical costs of motorcycle crashes in Ontario – Canadian Medical Association Journal (free)

Commentaries: Motorcycle crashes cause 5 times as many deaths as car accidents, 6 times the health costs – CMAJ, via EurekAlert (free) AND Motorcycle crashes are alarmingly common — and incredibly costly – STAT (free)

Management of anticoagulation in hip fractures – Effort Open Reviews (free)

Practice Guidelines for the Management of Multiligamentous Injuries of the Knee – Indian Journal of Orthopaedics (free)

European guidelines on perioperative venous thromboembolism prophylaxis (free PDF articles):

– Editorial

– Executive Summary

– Intensive care

– Mechanical prophylaxis

– Patients with preexisting coagulation disorders and after severe perioperative bleeding

– Inferior vena cava filters

– Cardiovascular and thoracic surgery

– Neurosurgery

– Surgery in the elderly

– Surgery in the obese patient

– Surgery during pregnancy and the immediate postpartum period

– Day surgery and fast-track surgery

– Chronic treatments with antiplatelet agents

– Aspirin

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research – The Lancet Neurology (free registration required)

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free)

Commentaries: Tranexamic acid: is it about time? – The Lancet (free) Rapid use of blood drug could save thousands of lives, study finds – The Guardian (free) AND Severely bleeding patients must receive lifesaving drug within minutes, not hours – London School of Hygiene & Tropical Medicine, via EurekAlert (free)

Surgical Management of Musculoskeletal Trauma – Surgical Clinics of North America (free)

Recent Updates of the Diagnosis and Prevention of Venous Thromboembolism in Patients with a Hip Fracture – Hip & Pelvis (free)

Diagnostic and therapeutic treatment modalities for acute lower gastrointestinal bleeding: a systematic review – Endoscopy International Open (free)

Percutaneous cholecystostomy in the management of high-risk patients presenting with acute cholecystitis: Timing and outcome at a single institution – American Journal of Surgery (link to abstract – $ for full-text)

Commentary: Percutaneous Cholecystostomy: An Alternative to Urgent Surgery for Cholecystitis? – Medscape (free registration required)

Stair-related injuries treated in United States emergency departments – The American Journal of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Injuries on stairs occur in all age groups and abilities – Reuters (free)

Simple preventive actions by parents linked to fewer child injuries – NIHR Signal (free)

Original article: Keeping Children Safe: a multicentre programme of research to increase the evidence base for preventing unintentional injuries in the home in the under-fives – Programme Grants for Applied Research (free)

“Children more than twice as likely to attend hospital for stair falls if safety gate not used. Home hazards studied” (RT @NIHR_DC see Tweet)

Rib Fractures: To Fix or Not to Fix? An Evidence-Based Algorithm – Korean Journal of Thoracic and Cardiovascular Surgery (free)

Managing Head Trauma in Children – The New York Times (10 articles per month are free)

Related Articles: Reducing Head CT Use for Children With Head Injuries in a Community Emergency Department – Pediatrics (link to abstract – $ for full-text) AND Development and Internal Validation of a Clinical Risk Score for Treating Children With Mild Head Trauma and Intracranial Injury – JAMA Pediatrics (free PDF) AND Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort stud – The Lancet (free PDF)

Pedestrian Struck by Vehicle: Pearls and Pitfalls of ED Management – emDocs (free)

Pancreatitis: Preventing catastrophic haemorrhage – World Journal of Gastroenterology (free)

Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis – British Journal of Surgery (link to abstract – $ for full-text)

See also a  related meta-analysis suggesting the safety of nonoperative treatment for uncomplicated cases (free) and a recent guideline that incorporates the possibility of non-operative treatment for uncomplicated disease (free)

“1st RCT to show uncomplicated appendicitis resolve even without antibiotics (let alone surgery)” (RT @villesallinen see Tweet)