General Interest

Pathways to independence: towards producing and using trustworthy evidence – The BMJ (free)

See Complete Series: Commercial Influence in Health: from Transparency to Independence (free articles)

Commentary: Time to end drug company distortion of medical evidence – The Conversation (free)


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Why is the world losing the fight against history’s most lethal disease? – The Guardian (free)

Opinion piece by Dr. Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization (WHO)


Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: What Can We Learn From The Apple Heart Study? – Cardiobrief (free)

“…nearly half a million people were required to identify a few hundred people with AF. (It should further be noted that we have no idea whether the patients identified in this group will even benefit from their diagnosis, since they may differ in important ways from AF patients identified by traditional means.)” (from Cardiobrief)


The second-hand effects of antibiotics: communicating the public health risks of drug resistance – JAC-Antimicrobial Resistance (free)


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Association between gifts from pharmaceutical companies to French general practitioners and their drug prescribing patterns in 2016: retrospective study using the French Transparency in Healthcare and National Health Data System databases – The BMJ (free)


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Reporting research findings to participants is an ethical imperative – The BMJ (free for a limited period)


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Sepsis hysteria: excess hype and unrealistic expectations – The Lancet (free)

Commentary: Sepsis myths create ‘unhealthy climate of fear’, say experts – The Guardian (free)

Source: Grupo UTIclínica – HCFMUSP


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Older Patients (Still) Left Out of Cancer Clinical Trials – JAMA (free for a limited period)

Related: Exclusion of patients with concomitant chronic conditions in ongoing randomised controlled trials targeting 10 common chronic conditions and registered at a systematic review of registration details – BMJ Open (free) AND Do cancer clinical trials exaggerate the real-world benefits of drugs? – STAT News (free)


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Trends in Internet Searches for Cannabidiol (CBD) in the United States – JAMA Network Open (free)

Commentaries: Interest in CBD products keeps soaring, but health experts wary – HealthDay (free) AND Online Searches For CBD Skyrocket – (free)


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12 Innovations That Will Change Health Care and Medicine in the 2020s – TIME (free)


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The Silent Heart Attack You Didn’t Know You Had – The New York Times (10 articles per month are free)

Related Studies: Silent Myocardial Infarction Often Precedes Sudden Cardiac Death (link to abstract and commentaries) AND Cohort Study: Long-term Outcomes of Unrecognized MI (link to abstract and commentaries)


Neurodegenerative Disease Mortality among Former Professional Soccer Players – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Dementia in football: Ex-players three and a half times more likely to die of condition – BBC (free) AND Study shows more thinking problems in former pro soccer players – Reuters (free)


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Neglecting Major Health Problems and Broadcasting Minor, Uncertain Issues in Lifestyle Science – JAMA (free for a limited period)


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Cascades of Care After Incidental Findings in a US National Survey of Physicians – JAMA Network Open (free)

Commentaries: The Important but Rarely Studied Cascade of Care – JAMA Network Open (free) AND Incidental Test Findings and the Burden They Create – MedPage Today (free registration required)

Related: Umbrella Review: Prevalence and Outcomes of Incidental Imaging Findings (free)


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Complexity in Assessing the Benefit vs Risk of Vaccines: Experience With Rotavirus and Dengue Virus Vaccines – JAMA (free for a limited period)

“At what threshold does a large reduction in disease burden for society justify the small risk of an adverse reaction to an individual?”


Offline: Touch—the first language – The Lancet (free)

Related: Of Slide Rules and Stethoscopes: AI and the Future of Doctoring – The Hastings Center Report (free)


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Are zombie doctors taking over America? – TEDMED (free)

Source: MedPage Today

“Physician Zubin Damania, Director of Healthcare Development for Downtown Project Las Vegas, has a plan to fight back against a system that can dehumanize doctors and patients alike.”


The Future of OA: A large-scale Analysis Projecting Open Access Publication and Readership – bioRxiv (free PDF)

News Release: The Future of OA: A large-scale analysis projecting Open Access publication and readership – Our Research Blog (free)


“In 2019:

31% of all journal articles are available as OA

52% of all article views are to OA articles


Given existing trends, we estimate that by 2025:

44% of all journal articles will be available as OA

70% of all article views will be to OA articles”


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The Folly of Big Science Awards – The New York Times (10 articles per month are free)


Podcast: In-Flight Emergencies

8 Oct, 2019 | 10:06h | UTC

I’ve noticed a change in my colleague’s behaviour. What should I do? – The BMJ (free) (via @brhospitalist)


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There’s a reason we don’t know much about AI – Politico (free)


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Poetry and Medicine: Dysthanasia

18 Sep, 2019 | 02:28h | UTC

Dysthanasia – JAMA (free for a limited period)


World Health Organization Campaign on World Patient Safety Day (free resources)

News Release: WHO calls for urgent action to reduce patient harm in healthcare (free)

See also: Patient Safety Fact Sheet (free) 10 facts on patient safety (free) AND The Lancet Editorial: Patient safety: too little, but not too late (free)


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2019 Ig Nobels Award Study That Found Surgeons Are Trained Better When Treated Like Dogs – (free)

See also: Training surgeons like dogs, icky money win 2019 Ig Nobels – Associated Press (free)

2018 Ig Nobel Awards: Ig Nobel Win for Kidney Stone Removing Roller-coaster (free commentaries)

Source: Training surgeons with clickers and warm scrotum studies win Ig Nobel awards – The BMJ ($)

“The Ig Nobel Prizes honor achievements that make people LAUGH, and then THINK. The prizes are intended to celebrate the unusual, honor the imaginative — and spur people’s interest in science, medicine, and technology.” (from About the Ig Nobel Prizes, in Improbable Research)


Lazarus in asystole: a case report of autoresuscitation after prolonged cardiac arrest – European Heart Journal Case Reports (free)


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Key Concepts for Making Informed Choices

15 Aug, 2019 | 07:47h | UTC

Too Much Medicine: Not Enough trust?

11 Aug, 2019 | 22:18h | UTC

Too Much Medicine: Not Enough trust? – Journal of Medical Ethics (free)


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Doctors: How Job Stress Can Age Us

31 Jul, 2019 | 01:59h | UTC

Opinion: Mandate Vaccination with Care

29 Jul, 2019 | 20:01h | UTC

Harms from Uninformative Clinical Trials – JAMA (free)

“An uninformative trial is one that provides results that are not of meaningful use for a patient, clinician, researcher, or policy maker.”


How a data detective exposed suspicious medical trials – Nature (free)

Related: Dozens of recent clinical trials may contain wrong or falsified data (free study by John Carlisle)

“Anaesthetist John Carlisle has spotted problems in hundreds of research papers — and spurred a leading medical journal to change its practice.”


Korean Alcohol Guidelines for Moderate Drinking Based on Facial Flushing – Korean Journal of Family Medicine (free PDF)

“individuals with flushing reaction should maintain an alcohol consumption level half of that for non-flushers.”


For the sake of doctors and patients, we must fix hospital culture – The BMJ Opinion (free)

Related: Speaking up to prevent harm: A systematic review of the safety voice literature – Safety Science (free)

“When hospitals fail to create a culture where doctors and nurses can speak up patients pay the price.”


Viewpoint: Redefining the Physician’s Role in Cost-Conscious Care: The Potential Role of the Electronic Health Record – JAMA (free for a limited period)

“Displaying price information in EHRs could mark the next step in the transformation of the practice of medicine… The next generation of EHRs should include prices for the majority of medical products and services: medications, laboratory testing, surgical procedures, and physician visits.”


Physician Burnout: A Global Crisis

12 Jul, 2019 | 07:57h | UTC