General Interest

To Save The Science Poster, Researchers Want To Kill It And Start Over – NPR (free)

Related Video: How to create a better research poster in less time (including templates) (free)


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Meta-Research: A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals – eLife (free)


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Editorial: ICD 11

11 Jun, 2019 | 03:13h | UTC

ICD 11 – The Lancet (free)

Related: WHO: ICD-11 is Here! (free resources)


Perspective: The War to Free Science

11 Jun, 2019 | 03:11h | UTC

The war to free science – Vox (free)

Related: Plan S: Making Full and Immediate Open Access a Reality (free) AND Open Access 2018: A Year of Funders and Universities Drawing Lines in the Sand (free)

“How librarians, pirates, and funders are liberating the world’s academic research from paywalls.”


Opinion: The Business of Health Care Depends on Exploiting Doctors and Nurses – The New York Times (10 articles per month are free)

“One resource seems infinite and free: the professionalism of caregivers.”


New preprint server for medical research – The BMJ (free)

See also: New preprint server for the health sciences announced today – Cold Spring Harbor Laboratory (CSHL) (free) AND How to bring preprints to the charged field of medicine – Nature News (free)


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Does the news reflect what we die from? – Our World in Data (free)

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At $2.1 Million, New Gene Therapy Is The Most Expensive Drug Ever – NPR (free)

See also: No Miracle Drug Should Cost $2.1 Million – Bloomberg Opinion (free) AND This New Treatment Could Save the Lives of Babies. But It Costs $2.1 Million. – The New York Times (10 articles per month are free)

“The price set by the Swiss drugmaker Novartis may be the world’s highest for a single treatment — prompting renewed debate about how society will pay for gene-therapy breakthroughs.” (from the New York Times)


A Contrarian View of Digital Health – Quillette (free)


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Prevalence of Burnout in Medical and Surgical Residents: A Meta-Analysis – International Journal of Environmental Research and Public Health (free)

The aggregate prevalence of burnout was 51.0% among residents. Subgroup analysis by specialty showed that radiology (77.16%), neurology (71.93%), and general surgery (58.39%) were the top three specialties with the highest prevalence of burnout.


Here’s why moderate drinking is probably not good for you – The Guardian (free)

“The problem is that moderate drinking isn’t an isolated behavior. You can’t easily separate moderate drinking from the people who drink moderately, which means that you can’t easily identify whether it’s actually the alcohol that’s improving people’s health or something more complex.”


Opinion: How to Make Doctors Think About Death – The New York Times (10 articles per month are free)

“End-of-life treatment guidelines would help families, physicians and nurses confront the inevitable with care and compassion.”


What Are Polygenic Scores and Why Are They Important? – JAMA (free for a limited period)

Related: How Scientists are Learning to Predict Your Future with Your Genes (free)

“Before polygenic scores can be translated into clinical practice they will need to be extensively validated in clinical and population-based cohorts for their ability to predict meaningful outcomes that can be modified with intervention.”


Global expansion and redistribution of Aedes-borne virus transmission risk with climate change – PLOS Neglected Tropical Diseases (free)

Commentaries: CHART: Where Disease-Carrying Mosquitoes Will Go In The Future – NPR (free) AND Mosquito-spread diseases may endanger millions in new places due to climate change – The Guardian (free)

Related: Climate Change — A Health Emergency (free reports and commentaries on the subject)


Relate Commentary on Twitter (interactive chart – click for more)


3 Ways AI is Already Changing Medicine

17 Mar, 2019 | 18:16h | UTC

The Case for Being a Medical Conservative – The American Journal of Medicine (free for a limited period)


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Comparative Accuracy of Diagnosis by Collective Intelligence of Multiple Physicians vs Individual Physicians – JAMA Network Open (free)

Editorial: Collective Intelligence for Clinical Diagnosis—Are 2 (or 3) Heads Better Than 1? (free)


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Television viewing and cognitive decline in older age: findings from the English Longitudinal Study of Ageing – Science Reports (free)

Commentaries: Expert reaction to study looking at watching TV and memory in over 50s – Science Media Centre (free) AND TV Viewing Tied to Cognitive Decline in Those Over Age 50 – NEJM Journal Watch (free)


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Measuring the Value of Health

4 Feb, 2019 | 22:36h | UTC

Measuring the value of health – Bill & Melinda Gates Foundation (free)


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A.I. Could Worsen Health Disparities – The New York Times (free)

“In a health system riddled with inequity, we risk making dangerous biases automated and invisible.”


A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy – New England Journal of Medicine (link to abstract – $ for full-text)

Editorial: The Dangerous Flavors of E-Cigarettes (free)

Commentaries: E-cigarettes more effective than nicotine replacement therapies, finds major trial – Queen Mary University of London (free) AND UK study shows e-cigarettes help adult smokers quit, but US experts urge caution – CNN (free) AND E-Cigarettes Are Effective at Helping Smokers Quit, a Study Says – The New York times (10 articles per month are free) AND E-cigarettes ‘much better for quitting smoking’ – BBC (free) AND Study Found Vaping Beat Traditional Smoking-Cessation Options – NPR (free)


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Are Probiotics Money Down the Toilet? Or Worse? – JAMA (free for a limited period)

Related: Randomized Trials: Probiotics Ineffective Against Gastroenteritis (link to abstract and commentaries) AND Perspective: The Problem with Probiotics (free commentaries) AND Probiotics: Does the Evidence Match the Hype? (link to abstract and commentaries) AND Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries)


This Is Your Brain Off Facebook – The New York Times (10 articles per month are free)

Original randomized trial, involving nearly 3000 individuals: The Welfare Effects of Social Media (free PDF)

“Expect the consequences to be fairly immediate: More in-person time with friends and family. Less political knowledge, but also less partisan fever. A small bump in one’s daily moods and life satisfaction. And, for the average Facebook user, an extra hour a day of downtime.”


Prevalence of Cannabis Use Among Medical Students: A Systematic Review and Meta-analysis – Substance Abuse: Research and Treatment (free)

“1 in 3 medical students has used cannabis, whereas 8.8% were current users”


Promises, promises, and precision medicine – JCI: The Journal of Clinical Investigation (free)

Related: Representing a “revolution”: how the popular press has portrayed personalized medicine – Genetics in Medicine (free)

“Hype vs. reality. Vast disconnect between actual achievements of “precision medicine” and how portrayed in popular culture” (via @CaulfieldTim see Tweet)


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The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report (free registration required)

Commentaries: Take on food industry to beat malnutrition and obesity, says report – The Guardian (free) AND Want to fix obesity and climate change at the same time? Make Big Food companies pay. – VOX (free) AND To fix climate change, fix the obesity and starvation epidemics, reports say – CNN (free)


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Injuries Associated With Standing Electric Scooter Use – JAMA Network Open (free)

Invited Commentary: Shareable 2-Wheeled Vehicles—A New Public Health Problem? (free)


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Should we rename low risk cancers? – The BMJ (free)


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Perspective: The Death of the Sick Day

24 Jan, 2019 | 21:41h | UTC

The Death of the Sick Day – The New York Times (free)

“For many office workers, “working from home” has replaced a day spent recovering under the covers.”


10 Global Health Issues to Watch in 2019

24 Jan, 2019 | 00:02h | UTC

Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems – The Lancet (free articles – registration required)

Summary: EAT-Lancet Commission Brief for Everyone (free)

Commentaries: New Diet Guidelines to Benefit People and the Planet: More Greens for All, Less Meat for Some – The New York Times (10 articles per month are free) AND New ‘planetary health diet’ can save lives and the planet, major review suggests – CNN (free) AND A bit of meat, a lot of veg – the flexitarian diet to feed 10bn – BBC (free)


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American College of Physicians Ethics Manual: Seventh Edition – Annals of Internal Medicine (free)

News Release: American College of Physicians releases new edition of Ethics Manual (free)

“Genetic testing, telemedicine, end-of-life care, and human subjects research are among issues examined in new edition of ACP Ethics Manual” (from News Release)


Carbohydrate quality and human health: a series of systematic reviews and meta-analyses – The Lancet (link to abstract – $ for full-text)

Commentaries: High intake of dietary fiber and whole grains associated with reduced risk of non-communicable diseases – ScienceDaily (free) AND High-fiber diet linked to lower risk of death and chronic diseases – CNN (free) AND Expert reaction to series of systematic reviews and meta-analyses about dietary fibre and the risk of non-communicable disease – Science Media Centre (free)


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Effectiveness of SIESTA on Objective and Subjective Metrics of Nighttime Hospital Sleep Disruptors – Journal of Hospital Medicine (free)

Commentary: Hospital SIESTA project reduces inpatient sleep interruptions – University of Chicago Medical Center (free)


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Effect of a Biobehavioral Environmental Approach on Disability Among Low-Income Older Adults: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentaries: Home Modifications to Reduce Disability in Older Adults With Functional Disability – JAMA Internal Medicine (free for a limited period)


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Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life – Cochrane Library (free)

Summary: Vitamin and mineral supplementation for preventing cognitive deterioration in cognitively healthy people in mid and late life – Cochrane Library (free)

Commentary: Preventing dementia: do vitamin and mineral supplements have a role? – Evidently Cochrane (free)


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Comparison of Nicotine and Toxicant Exposure in Users of Electronic Cigarettes and Combustible Cigarettes – JAMA Network Open (free)

Commentaries: Will the Debate Over e-Cigarettes Start Cooling Down? – JAMA Network Open (free) AND E-cigarettes less toxic to users than cigarettes, study says – CNN (free)


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Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial – The BMJ (free)

Linked Opinion: We jumped from planes without parachutes (and lived to tell the tale) – The BMJ Opinion (free)

Commentaries: Researchers Show Parachutes Don’t Work, But There’s A Catch – NPR (free) AND Evidence-Based Satire – The Health Care Blog (free)


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U.S. News’ 41 Best Diets Overall

4 Jan, 2019 | 20:14h | UTC

Questions for Artificial Intelligence in Health Care – JAMA (free for a limited period)

Related: Humanizing Artificial Intelligence – JAMA (free for a limited period)


WHO: Why the HIV Epidemic is Not Over

4 Dec, 2018 | 00:04h | UTC

Why Hospitals Should Let You Sleep – The New York Times (10 articles per month are free)

“Frequent disruptions are more than just annoying for patients. They can also cause harm.”


2018 Global Nutrition Report

2 Dec, 2018 | 23:25h | UTC

Medical Screening Tests You Do and Don’t Need – Consumer Reports (free) (via @EricTopol)

“Some may be life-saving, but others can waste time and money—and pose risks”


Editorial: We Need to Talk About Meat

2 Dec, 2018 | 23:03h | UTC

Assessment of Pregabalin Postapproval Trials and the Suggestion of Efficacy for New Indications: A Systematic Review – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Some research may be encouraging ineffective prescriptions, says new study – McGill University (free)

“Our point is not to condemn these individual trials. Instead, we are saying that—when you zoom out and look at what’s happening at the level of the forest—the trees begin to look less healthy.” (from McGill University)