Study: Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding

22Aug
2017

Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding (CONCERN): an industry-independent, double-blind, double-dummy, randomised trial – The Lancet (link to abstract – $ for full-text)

Source: ACP Journal Club

In this study, patients at high risk of both cardiovascular and gastrointestinal events who required concomitant aspirin and NSAID, celecoxib associated with a proton pump inhibitor led to less recurrent gastrointestinal bleeding when compared to naproxen associated with a proton pump inhibitor (5.6% vs 12.3%).

 

Guideline: Gastrointestinal Sarcomas (GIST)

22Aug
2017

Guideline: Living Donor Liver Transplant Recipient

22Aug
2017

Re-analysis of the USPSTF 2016 Evidence Report on Colorectal Cancer Screening

22Aug
2017

Guideline: Management of Inherited Polyposis Syndromes

22Aug
2017

Free Online Course: Anatomy of the Abdomen and Pelvis

21Aug
2017

The role of bariatric surgery to treat diabetes

17Aug
2017

Effect of scheduled second-look endoscopy on peptic ulcer bleeding

16Aug
2017

Effect of scheduled second-look endoscopy on peptic ulcer bleeding: a prospective randomized multicenter trial – Gastrointestinal Endoscopy (link to abstract – $ for full-text)

Source: No Benefit of Second-Look Endoscopy After Endoscopic Hemostasis – Journal Watch ($)

“A single EGD with endoscopic hemostasis is not inferior to scheduled second-look endoscopy in terms of reduction in rebleeding rate of peptic ulcer bleeding. Repeat endoscopy would be helpful in the patients with unsatisfactory initial endoscopic hemostasis, use of NSAIDs, and larger amounts of transfused blood”

 

FDA Safety Alert: Liquid-filled Intragastric Balloon Systems

16Aug
2017

The Risk of Adverse Pregnancy Outcomes Following Nonobstetric Surgery During Pregnancy

16Aug
2017

The Risk of Adverse Pregnancy Outcomes Following Nonobstetric Surgery During Pregnancy: Estimates From a Retrospective Cohort Study of 6.5 Million Pregnancies – Annals of Surgery (free)

Source: Journal Watch ($)

“we found that the risk associated with nonobstetric surgery was relatively low, confirming that surgical procedures during pregnancy are generally safe”

 

Dexamethasone before bowel surgery reduces postoperative nausea and vomiting

15Aug
2017

Surgery must be a core part of health care – even in the poorest countries

15Aug
2017

Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment

15Aug
2017

Colorectal endoscopic submucosal dissection: patient selection and special considerations

15Aug
2017

Risk factors for conversion of laparoscopic cholecystectomy to open surgery

11Aug
2017

Diarrhea after bariatric procedures: Diagnosis and therapy

11Aug
2017

Present and future of metastatic colorectal cancer treatment

11Aug
2017

Diet and Risk of Cholecystectomy

10Aug
2017

Surgical Guidelines for Perioperative Management of Older Adults

10Aug
2017

What treatment in 2017 for inoperable pancreatic cancers?

10Aug
2017

Acute mesenteric ischemia: guidelines

9Aug
2017

Transition of adolescent and young persons with chronic digestive diseases from paediatric to adult care

9Aug
2017

Factors Associated With Achieving a Body Mass Index of Less Than 30 After Bariatric Surgery

5Aug
2017

Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition

5Aug
2017

Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update

3Aug
2017

Management of metastatic colorectal cancer patients

3Aug
2017

Clinical Practice Guidelines for Cryosurgery of Pancreatic Cancer

3Aug
2017

Laparoscopy in Blunt Abdominal Trauma: for Whom? When?and Why?

1Aug
2017

Advances in surgical management for locally recurrent rectal cancer

28Jul
2017

Endoscopic ultrasound in oncology: An update of clinical applications in the gastrointestinal tract

28Jul
2017

Endoscopic recommendations for colorectal cancer screening and surveillance in patients with inflammatory bowel disease

28Jul
2017

Update in the assessment and management of intraductal papillary mucinous neoplasms of the pancreas

27Jul
2017

Advances in the Diagnosis and Management of Colonic Dysplasia in Patients With Inflammatory Bowel Disease

27Jul
2017

Guidelines for the understanding and management of pain in chronic pancreatitis

27Jul
2017

Enhanced recovery pathway for colorectal surgical patients improves outcomes, reduces cost

25Jul
2017

American College of Surgeons (ACS) 2017 Quality and Patient Safety Conference: Enhanced recovery pathway for colorectal surgical patients improves outcomes, reduces cost – ACS, via EurekAlert (free)

Related guideline: Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons (free)

See other Enhanced Recovery After Surgery (ERAS) Guidelines and Reviews in our collection and in the ERAS Society Website.

“Successful protocol shortens hospital stays, reduces patients’ risk of complications, and cuts costs up to $11,000 per procedure”

 

Guideline: Damage control resuscitation in patients with severe traumatic hemorrhage

25Jul
2017

Reducing Smoking Rates for Patients Facing Surgery

25Jul
2017

2017 ACS Quality and Safety Conference: “Strong for Surgery” Shows Promise in Reducing Smoking Rates for Patients Facing Surgery – American College of Surgeons, via NewsWise (free)

“Study suggests big drop in smoking rates when surgeons help patients quit before their operations”.

 

Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome

23Jul
2017

Guidelines for the diagnosis and therapy of chronic pancreatitis

23Jul
2017

What carcinoembryonic antigen level should trigger further investigation during colorectal cancer follow-up?

23Jul
2017

What carcinoembryonic antigen level should trigger further investigation during colorectal cancer follow-up? A systematic review and secondary analysis of a randomised controlled trial – Health Technology Assessment (free)

Source: ACP Journal Wise ($)

“The results suggest that (1) CEA testing should not be used alone as a triage test; (2) in year 1, testing frequency should be increased (to monthly for 3 months and then every 2 months); (3) the threshold for investigating a single test result should be raised to 10 µg/l; (4) after the second CEA test, decisions to investigate further should be made on the basis of the trend in CEA levels; (5) the optimal threshold for investigating the CEA trend falls over time; and (6) continuing smokers should not be monitored with CEA testing”.

 

The Evolving Story of Overlapping Surgery

23Jul
2017

Viewpoint: The Evolving Story of Overlapping Surgery – JAMA (free) (RT @pash22 see Tweet)

Commentary: 3 steps to restore patient trust in overlapping surgeries – FierceHealthcare (free)

This interesting viewpoint discusses the practice of scheduling overlapping surgeries, in which a qualified practitioner finishes noncritical parts of the first operation while the primary surgeon moves to the next surgery.

 

Guideline: Molecular Biomarkers for the Evaluation of Colorectal Cancer

22Jul
2017

Approach to cytomegalovirus infections in patients with ulcerative colitis

21Jul
2017

New European Society of Medical Oncology (ESMO) Updated Clinical Practice Guidelines

20Jul
2017

Guideline: Neuroendocrine neoplasms of the small intestine and appendix

18Jul
2017

Guideline: Colorectal neuroendocrine neoplasms

18Jul
2017

Guideline: Pancreatic neuroendocrine neoplasms

18Jul
2017

Guideline: Gastroduodenal neuroendocrine neoplasms, including gastrinoma

18Jul
2017

Update on the first-line treatment for Helicobacter pylori infection

18Jul
2017

Optimal diagnosis and disease activity monitoring of intestinal Behçet’s disease

18Jul
2017

Treatment and outcomes: medical and surgical treatment for intestinal Behçet’s disease

18Jul
2017

Prevalence, Pathogenesis, Diagnosis, and Management of Microscopic Colitis

18Jul
2017

Guideline: The management of intra-abdominal infections from a global perspective

17Jul
2017

Hereditary pancreatic cancer: related syndromes and clinical perspective

16Jul
2017

Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery

16Jul
2017

NCCN Guidelines Insights: Antiemesis

13Jul
2017

Post-Surgical Complications

11Jul
2017

Post-Surgical Complications – emDocs (free)

Practical review of this common problem in the emergency department.

 

The relationship between eosinophilic esophagitis and esophageal cancer

11Jul
2017

The relationship between eosinophilic esophagitis and esophageal cancer – Diseases of The Esophagus (free)

An analysis of a large database of de-identified electronic medical records (EMRs) with over 40.000.000 patients found no association.

 

Association of delay of urgent or emergency surgery with mortality and use of health care resources

10Jul
2017

Guideline – Management of Crohn’s disease

7Jul
2017

Guideline – Management of ulcerative colitis

7Jul
2017

Cases of recurrent Clostridium difficile infection are increasing

7Jul
2017

Current Status of Immune Checkpoint Inhibitors in Gastrointestinal Cancers

7Jul
2017

Multidisciplinary approach of colorectal cancer liver metastases

7Jul
2017

Magnetic resonance imaging for diagnosis and neoadjuvant treatment evaluation in locally advanced rectal cancer

7Jul
2017

Immunotherapy in pancreatic cancer

7Jul
2017

Updates in Mirizzi syndrome

7Jul
2017

Pancreatic Ductal Adenocarcinoma: Current and Evolving Therapies

7Jul
2017

Risk of death among users of Proton Pump Inhibitors

5Jul
2017

Re-designing the pathway to surgery: better care and added value

3Jul
2017

Complications of Proton Pump Inhibitor Therapy

30Jun
2017

Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free)

Commentary: Complications of Proton Pump Inhibitor Therapy – PracticeUpdate (free registration required)

Related: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD – Journal of the American Society of Nephrology (link to abstract – registration required for full text) AND Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis – Jama Neurology (link to abstract – subscription required for full text)

The authors of this review argue that the observational studies that brought up the safety issues associated with PPIs (above studies, for example) are insufficient to establish causation and suggest a more balanced approach to PPI prescribing.

 

Colorectal polypectomy and endoscopic mucosal resection

29Jun
2017

Monitoring Medical Devices: Missed Warning Signs Within Existing Data

26Jun
2017

Viewpoint: Monitoring Medical Devices: Missed Warning Signs Within Existing Data – JAMA (free)

Related: The lap band for weight loss is a tale of medicine gone wrong – VOX (free) Reoperation and Medicare Expenditures After Laparoscopic Gastric Band Surgery – JAMA Surgery (link to abstract – $ for full-text) AND Safety, Effectiveness of Gastric Banding Called Into Question – Medscape (free registration required) AND 1 In 5 Gastric Band Surgeries Require Corrective Operations – American Council on Science and Health (free)

The authors use the example of gastric band surgery to discuss how available data may be used more appropriately for earlier detection of problems in the safety of medical devices.

 

A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery

26Jun
2017

A Meta-analysis of the Impact of Aspirin, Clopidogrel, and Dual Antiplatelet Therapy on Bleeding Complications in Noncardiac Surgery – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts (free resource to find articles of interest)

“Antiplatelet therapy at the time of noncardiac surgery confers minimal bleeding risk with no difference in thrombotic complications. In many cases, it is safe to continue antiplatelet therapy in patients with important indications for their use”

 

Diagnostic Accuracy of Fecal Immunochemical Test in Patients at Increased Risk for Colorectal Cancer

25Jun
2017

ACG and CAG Clinical Guideline: Management of Dyspepsia

23Jun
2017

Guidelines for the Management of Cancer of the Colon, Rectum and Anus

23Jun
2017

Update on anti-TNF agents and other new drugs for IBD

23Jun
2017

Aspirin and other NSAIDs and colorectal cancer survival

21Jun
2017

Timing of Aspirin and Other Nonsteroidal Anti-Inflammatory Drug Use Among Patients With Colorectal Cancer in Relation to Tumor Markers and Survival – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentary: Study Informs NSAID Benefit in Colon Cancer – MedPage Today (free registration required)

Observational data suggests a benefit for individuals with KRAS wild-type tumors

 

New colorectal cancer screening guidelines

20Jun
2017

Antiplatelet Therapy in Patients With Coronary Stents Undergoing Elective Noncardiac Surgery

20Jun
2017

Surgeon Variation in Complications With Minimally Invasive and Open Colectomy

20Jun
2017

Surgeon Variation in Complications With Minimally Invasive and Open Colectomy: Results From the Michigan Surgical Quality Collaborative – JAMA Surgery (free) (RT @MaryDixonWoods see Tweet)

Surgeon-level variation in complications among surgeons was nearly twice as great for Minimally Invasive Colectomy than for Open Colectomy, implying a need for improved training in adoption of minimally invasive techniques.

 

Inspired by War Zones, Balloon Device May Save Civilians From Fatal Blood Loss

20Jun
2017

Development and validation of risk prediction equations to estimate survival in patients with colorectal cancer

19Jun
2017

Guidelines for gastro-entero-pancreatic neuroendocrine neoplasms

19Jun
2017

Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma

16Jun
2017

Pancreatic Adenocarcinoma: Improving Prevention and Survivorship

16Jun
2017

Inflammatory Bowel Disease in Childhood and Adolescence

16Jun
2017

Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events

15Jun
2017

Practice Guidelines for Preoperative Fasting

9Jun
2017

#ASCO2017 – Risk-Based Approach to Chemotherapy Duration Recommended for Stage III Colon Cancer

7Jun
2017

Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (again)

7Jun
2017

Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis: Systematic Review and Meta-analysis of Controlled Trials – Annals of Surgery (link to abstract – $ for full-text)

Commentary: Antibiotics Versus Surgery: Equally Effective in Treating Appendicitis? – Medscape (free registration required)

This meta-analysis and the author’s conclusions do not favor antibiotics alone for the treatment of uncomplicated appendicitis, contradiction the results of other recent meta-analysis, as well as a recent guideline on the subject, suggesting antibiotics might be an option in selected cases.

 

Inflammatory bowel disease: Five things physicians and patients should question

7Jun
2017

Guidelines on the Management of Intra-Abdominal Infection

26May
2017

The lap band for weight loss is a tale of medicine gone wrong

25May
2017

Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery

25May
2017

Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial – JAMA Surgery (free) (RT @PreetiNMalani see Tweet)

Commentary: Anti-delirium strategy reduces after-surgery confusion in elderly – Reuters Health (free)

Multicomponent nonpharmacologic interventions, including orienting communications, oral and nutritional assistance, and early mobilization reduced postoperative delirium by 56% and length of stay by 2 days.

 

Reoperation and Medicare Expenditures After Laparoscopic Gastric Band Surgery

23May
2017

Recent advances in the management of variceal bleeding

16May
2017

Management of intra-abdominal infections

15May
2017

Hepatobiliary Cancers – NCCN Guidelines Insights

12May
2017
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