Open access
Open access
Powered by Google Translator Translator

Gastroenterology (all articles)

AGA Practical Guidance | Diagnosis and management of extraesophageal gastroesophageal reflux disease

25 Apr, 2023 | 14:50h | UTC

AGA Clinical Practice Update on the Diagnosis and Management of Extraesophageal Gastroesophageal Reflux Disease: Expert Review – Clinical Gastroenterology and Hepatology

Commentary: Guidance offered on management of extraesophageal GERD – ACP Gastroenterology

 

Commentary on Twitter (thread – click for more)

 

Review | New treatment paradigms in primary biliary cholangitis

26 Apr, 2023 | 13:49h | UTC

New Treatment Paradigms in Primary Biliary Cholangitis – Clinical Gastroenterology and Hepatology

 

Perspective | Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms

25 Apr, 2023 | 14:37h | UTC

Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms – Intensive Care Medicine

 

Commentary on Twitter

 

Brief Review | Diagnosis and management of neuroendocrine tumors

25 Apr, 2023 | 14:16h | UTC

Diagnosis and management of neuroendocrine tumours – Clinical Medicine Journal

 

RCT | Bariatric–metabolic surgery is more effective than lifestyle intervention plus best medical care in non-alcoholic steatohepatitis

24 Apr, 2023 | 14:03h | UTC

Bariatric–metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial – The Lancet

News Release: Surgery most effective treatment of metabolic liver disease – King’s College London

 

Commentary on Twitter

 

SR | Etiology, diagnosis, and modern management of chronic pancreatitis

24 Apr, 2023 | 13:29h | UTC

Etiology, Diagnosis, and Modern Management of Chronic Pancreatitis: A Systematic Review – JAMA Surgery (free for a limited period)

 

M-A | Adverse events related to tirzepatide (a dual GIP/GLP-1 receptor agonist)

21 Apr, 2023 | 12:59h | UTC

Adverse Events Related to Tirzepatide – Journal of the Endocrine Society

Related:

RCT | Safety and efficacy of Tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan.

Tirzepatide Once Weekly for the Treatment of Obesity – New England Journal of Medicine

Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis – Diabetologia

Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis – Nature Medicine

Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

 

Guideline | Management of psychiatric disorders in patients with hepatic and gastrointestinal diseases

19 Apr, 2023 | 13:07h | UTC

Management of Psychiatric Disorders in Patients with Hepatic and Gastrointestinal Diseases – Indian Journal of Psychiatry

 

Guideline | Intrahepatic cholestasis of pregnancy

18 Apr, 2023 | 13:24h | UTC

Intrahepatic cholestasis of pregnancy – BJOG

 

Brief Review | Chronic cough and inflammatory bowel disease: an under-recognized association?

18 Apr, 2023 | 13:07h | UTC

Chronic cough and inflammatory bowel disease: an under-recognised association? – Breathe

 

Commentary on Twitter

 

Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU

17 Apr, 2023 | 13:19h | UTC

Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Neurology, Peri-Transplant Medicine, Infectious Disease, and Gastroenterology Considerations – Critical Care Medicine (free for a limited period)

Executive Summary: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Neurology, Peri-Transplant Medicine, Infectious Disease, and Gastroenterology Considerations – Critical Care Medicine (free for a limited period)

 

Review | Diagnostic, structured classification and therapeutic approach in cystic pancreatic lesions

12 Apr, 2023 | 12:58h | UTC

Diagnostic, Structured Classification and Therapeutic Approach in Cystic Pancreatic Lesions: Systematic Findings with Regard to the European Guidelines – Diagnostics

Related:

Diagnostic Approach to Incidentally Detected Pancreatic Cystic Lesions – Current Treatment Options in Gastroenterology

Cystic pancreatic lesions: MR imaging findings and management.

Recommendations for the management of incidental pancreatic findings in adults.

Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management

Management of Pancreatic Cystic Lesions

Consensus Recommendations: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions

Review: Pancreatic Cystic Lesions

Guidelines on pancreatic cystic neoplasms

 

Screening colonoscopy in seniors: common in patients with limited life expectancy and associated with higher complication risks

11 Apr, 2023 | 14:30h | UTC

Frequency of Use and Outcomes of Colonoscopy in Individuals Older Than 75 Years – JAMA Internal Medicine (link to abstract – $ for full-text)

Related: Study reveals overuse of surveillance colonoscopy in older adults with limited life expectancy

 

Commentary:

 

M-A | Irritable bowel syndrome is not associated with an increased risk of polyps and colorectal cancer

11 Apr, 2023 | 14:19h | UTC

Irritable Bowel Syndrome Is Not Associated with an Increased Risk of Polyps and Colorectal Cancer: A Systematic Review and Meta-Analysis – Digestive Diseases and Sciences

 

Review | Anticoagulation in patients with liver cirrhosis: friend or foe?

11 Apr, 2023 | 14:17h | UTC

Anticoagulation in Patients with Liver Cirrhosis: Friend or Foe? – Digestive Diseases and Sciences

 

Review | Assessing the risk of surgery in patients with cirrhosis

10 Apr, 2023 | 13:20h | UTC

Assessing the risk of surgery in patients with cirrhosis – Hepatology Communications

 

Global epidemiology of cirrhosis — Etiology, trends and predictions

6 Apr, 2023 | 13:27h | UTC

Global epidemiology of cirrhosis — aetiology, trends and predictions – Nature Reviews Gastroenterology & Hepatology

 

Commentary on Twitter

 

RCT | Etrasimod outperforms placebo in ulcerative colitis induction & maintenance

6 Apr, 2023 | 12:56h | UTC

Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies – The Lancet

 

Commentary on Twitter

 

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019

5 Apr, 2023 | 13:27h | UTC

Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global Burden of Disease Study 2019 – BMJ Open

 

Two FITs better than one: enhancing diagnostic performance for colorectal cancer in symptomatic populations

4 Apr, 2023 | 13:32h | UTC

Double faecal immunochemical testing in patients with symptoms suspicious of colorectal cancer – British Journal of Surgery

 

Brief Review | What every gastroenterologist should know about gastrointestinal neuroendocrine tumors

4 Apr, 2023 | 13:29h | UTC

What Every Gastroenterologist Should Know About Gastrointestinal NETs – American Journal of Gastroenterology

 

RCT | Comparable efficacy of cefotaxime, ceftriaxone, and ciprofloxacin in treating spontaneous bacterial peritonitis

3 Apr, 2023 | 14:01h | UTC

Summary: This multicenter, prospective, open-label, randomized controlled trial compared the efficacy of cefotaxime, ceftriaxone, and ciprofloxacin as initial treatments for spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and ascites. The study included 261 patients aged 16 to 75, with liver cirrhosis, ascites, and a polymorphonuclear cell count of >250/mm3. Researchers performed follow-up paracentesis at 48 hours to evaluate the assigned antibiotics, and assessed resolution rates at 120 and 168 hours of treatment.

The primary endpoint, resolution rates at 120 hours, showed no statistically significant difference between the groups: 67.8% for cefotaxime, 77.0% for ceftriaxone, and 73.6% for ciprofloxacin. One-month mortality rates were also similar. The study concluded that these antibiotics are equally effective as initial treatments for SBP, particularly for community-acquired infections, when administered based on response-guided therapy.

Article: Response-Guided Therapy With Cefotaxime, Ceftriaxone, or Ciprofloxacin for Spontaneous Bacterial Peritonitis: A Randomized Trial: A Validation Study of 2021 AASLD Practice Guidance for SBP – American Journal of Gastroenterology (free for a limited period)

 

Gastric Cancer: the combined impact of H. pylori infection and pathogenic gene variants

3 Apr, 2023 | 13:51h | UTC

Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Helicobacter Pylori Infection Modifies the Risk of Gastric Cancer Associated with Germline Pathogenic Variants in Homologous Recombination Genes – ESMO

Commentary: H. Pylori Infection Negatively Modifies Genetically Increased Risk for Gastric Cancer – Physician’s Weekly

 

Commentary on Twitter

 

RCT | Vedolizumab for the treatment of chronic pouchitis

3 Apr, 2023 | 13:49h | UTC

Vedolizumab for the Treatment of Chronic Pouchitis – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: New hope for patients after vedolizumab found effective to treat Chronic Pouchitis – University of Oxford

 

Commentary on Twitter

 

Overcoming size disparity in liver transplant access: prioritizing smaller donors for smaller candidates

3 Apr, 2023 | 13:41h | UTC

Association of Body Surface Area With Access to Deceased Donor Liver Transplant and Novel Allocation Policies – JAMA Surgery (free for a limited period)

Invited Commentary: Addressing Size-Based Disparities in Liver Transplant – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.