Gastroenterology

The global burden of non-typhoidal salmonella invasive disease: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Infectious Diseases (free)

Invited Commentary: Non-typhoidal salmonella: invasive, lethal, and on the loose (free)

 

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Multiple-dose versus single-dose ivermectin for Strongyloides stercoralis infection (Strong Treat 1 to 4): a multicentre, open-label, phase 3, randomised controlled superiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 

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Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline – The BMJ (free)

Editorial: Personalised and risk based cancer screening (free)

Related Study: Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study – The BMJ (free)

Commentaries: Guideline Moves Away from Colorectal Cancer Screening for Some – NEJM Journal Watch (free) AND First Guideline to Say Colon Cancer Screening Is Not for All – Medscape (free registration required)

Related Guidelines: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)

 

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Efficacy of Prophylactic Hemoclips in Prevention of Delayed Post-Polypectomy Bleeding in Patients With Large Colonic Polyps – Gastroenterology (link to abstract – $ for full-text)

See related study with conflicting results: Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial (link to abstract – $ for full-text)

Source: EvidenceAlerts

 

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Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial – Gastroenterology (free for a limited period)

See related study with conflicting results: Randomized Trial: Prophylactic Hemoclips Not Beneficial for Prevention of Important Delayed Post-Polypectomy Bleeding in Patients with Large Colonic Polyps (free for a limited period)

Source: EvidenceAlerts

 

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Clinical Approach to Lactose Intolerance

27 Sep, 2019 | 08:31h | UTC

Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial – The BMJ (free)

 

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Review: Barrett Esophagus

3 Sep, 2019 | 01:09h | UTC

Consensus on Non-cardiac Chest Pain

1 Aug, 2019 | 08:52h | UTC

Early TIPS with covered stents versus standard treatment for acute variceal bleeding in patients with advanced cirrhosis: a randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

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Clinical Guide and Update on Porphyrias

26 Jul, 2019 | 01:11h | UTC

Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients With Achalasia: A Randomized Clinical Trial – JAMA (free)

Commentary: Peroral Endoscopic Myotomy an Upfront Option for Achalasia – Medscape (free registration required)

 

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Review: Ulcerative Colitis

3 Jul, 2019 | 06:10h | UTC

Choosing Wisely Canada-Top Five List in Hepatology: Official Position Statement of the Canadian Association for the Study of the Liver (CASL) and Choosing Wisely Canada (CWC) – Annals of Hepatology (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

1 – Don’t order serum ammonia to diagnose or manage hepatic encephalopathy (HE).

2 – Don’t routinely transfuse fresh frozen plasma, platelets or give Vitamin K to reverse abnormal tests of coagulation in patients with cirrhosis prior to abdominal paracentesis, endoscopic variceal band ligation, or any other minor invasive procedures.

3 – Don’t order HFE genotyping based on serum ferritin values alone to diagnose hereditary hemochromatosis.

4 – Don’t perform computed tomography (CT) or magnetic resonance imaging (MRI) routinely to monitor benign focal liver lesions (ex. focal nodal hyperplasia, hemangioma).

5 – Don’t repeat hepatitis C viral load testing in an individual who has established chronic infection, outside of antiviral treatment.

(Under a Creative Commons license)

 


Current Concepts in Acute Liver Failure

22 May, 2019 | 06:00h | UTC

Review: Chronic Constipation

2 May, 2019 | 04:31h | UTC

Chronic Constipation – Mayo Clinic Proceedings (free)

Related: Indian Consensus on Chronic Constipation in Adults (free guidelines and reviews on the subject)

 


Colorectal Cancer Screening – JAMA (free for a limited period)

Related: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)

 


Review: Hepatorenal Syndrome

24 Apr, 2019 | 06:21h | UTC

Review: Clostridium Difficile Infection

21 Apr, 2019 | 21:16h | UTC

Ilececum: A Comprehensive Review

20 Apr, 2019 | 13:34h | UTC

Grand Round: Autoimmune Hepatitis

15 Apr, 2019 | 02:20h | UTC

EASL Clinical Practice Guidelines: Drug-induced liver injury – Journal of Hepatology (free)

Related Review: Drug-induced liver injury: recent advances in diagnosis and risk assessment – Gut (free)

 

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Review article: treatment options for functional dyspepsia – Alimentary Pharmacology and Therapeutics (free)

“None of the available therapies is effective in the majority of patients without being associated with major side effects.”