Family Medicine
SR | Long‐acting muscarinic antagonist (LAMA) plus long‐acting beta‐agonist (LABA) vs. LABA plus inhaled corticosteroid (ICS) for COPD
20 Jun, 2023 | 12:26h | UTC
RCT | Testosterone replacement does not appear to increase cardiovascular events in hypogonadal men at high risk
19 Jun, 2023 | 14:13h | UTCCardiovascular Safety of Testosterone-Replacement Therapy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Presented today at #ENDO2023: In the TRAVERSE study, a randomized trial involving men with hypogonadism and preexisting or a risk of cardiovascular disease, testosterone therapy was noninferior to placebo with respect to major adverse cardiac events. https://t.co/V3FTTsOLd1
— NEJM (@NEJM) June 16, 2023
Review | Celiac disease: who should I test, and how?
19 Jun, 2023 | 13:54h | UTCCeliac disease: Who should I test, and how? – Cleveland Clinic Journal of Medicine
Review | Role of GLP1 receptor agonists in achieving weight loss and improving CV outcomes in people with overweight and obesity
19 Jun, 2023 | 13:40h | UTC
Brief Review | Why is cuff size so important and other factors that affect accurate blood pressure measurement
16 Jun, 2023 | 14:12h | UTC
Cohort Study | Alcohol consumption and risks of more than 200 diseases in Chinese men
16 Jun, 2023 | 13:55h | UTCAlcohol consumption and risks of more than 200 diseases in Chinese men – Nature Medicine
News Release: Alcohol consumption increases the risks of over 60 diseases – University of Oxford
Consensus Statement | Concussion in sport
15 Jun, 2023 | 15:14h | UTC
Evidence-based clinical practice guideline for deprescribing opioid analgesics
15 Jun, 2023 | 15:08h | UTC
RCT | Cannabis-based medicines show no significant relief for moderate-to-severe cancer pain
15 Jun, 2023 | 15:10h | UTCCannabis‐based medicines and medical cannabis for adults with cancer pain – Cochrane Library
Summary: Cannabis-based medicines for cancer pain – Cochrane Library
RCT | No significant kidney outcome differences observed across glucose-lowering medications in T2D patients
15 Jun, 2023 | 15:02h | UTCComparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes: The GRADE Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
See also: Visual Abstract
Commentaries:
No differences found in effects of secondary diabetes drugs on kidney outcomes – ACP Diabetes
Do glucose-lowering medications have different effects on kidney outcomes? – News Medical
SR | Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes
15 Jun, 2023 | 14:57h | UTC
Cohort Study | 63.1% of uncomplicated appendicitis in children successfully treated non-operatively at 1 year
15 Jun, 2023 | 14:45h | UTC
Commentary on Twitter
1y outcomes of CASCADE examining?treatment for uncomp?itis in kids ➡️overall success: 63.1%, 21.5% req?during hospitalisation, 10.4% recurrence @1y. Overall comp: 7.3%?vs. 1.3% in success Non?treatment. Thoughts?https://t.co/AuIgSKkU6w#SoMe4Surgery #some4peds #emgensurg pic.twitter.com/9mM5NFOEh1
— BJS Open (@BjsOpen) June 7, 2023
M-A | Postpartum care up to 1 year after pregnancy
14 Jun, 2023 | 14:39h | UTC
SR | Management of postpartum hypertensive disorders of pregnancy
14 Jun, 2023 | 14:37h | UTC
M-A | Oseltamivir fails to lower hospitalization risk in adult and adolescent influenza patients
13 Jun, 2023 | 14:12h | UTC
Commentary on Twitter
In this systematic review and meta-analysis of 15 RCTs, oseltamivir was not associated with reduced risk of first hospitalization compared with placebo or standard of care among influenza-infected adult and adolescent outpatients. https://t.co/UEqsbA2JQZ
— JAMA Internal Medicine (@JAMAInternalMed) June 12, 2023
Review | Diagnosis and management of depression in adolescents
13 Jun, 2023 | 14:05h | UTCDiagnosis and management of depression in adolescents – Canadian Medical Association Journal
News Release: How to diagnose and manage depression in adolescents: A new review for clinicians – Canadian Medical Association Journal
Review | The cervical spine in tension type headache
13 Jun, 2023 | 13:58h | UTCThe cervical spine in tension type headache – Musculoskeletal Science and Practice
Commentary on Twitter
The cervical spine in tension type headache
???https://t.co/EFcxBlDO34 pic.twitter.com/y7SyA3T7qt
— Physio Meets Science (@PhysioMeScience) June 1, 2023
Review | Post-intensive care syndrome
13 Jun, 2023 | 13:44h | UTCPost-intensive care syndrome (PICS): recent updates – Journal of Intensive Care
M-A | Elevated HbA1c in gestational diabetes mellitus tied to 1.7-fold rise in large for gestational age incidence
13 Jun, 2023 | 13:39h | UTC
2ry Analysis of a RCT | Metformin linked to 41% reduction in long COVID incidence in outpatient treatment
12 Jun, 2023 | 13:55h | UTCNews Release: Study shows metformin lowers the risk of getting long COVID – University of Minnesota Medical School
Commentary on Twitter
These data not persuasive. There are 6 different arms. 3 drugs. This is not the primary endpoint. No adjustment for multiple testing.
Even USFDA would not accept these data for regulatory approval, and they are basically working for Pharma at this pthttps://t.co/FZoxo9shtG
— Vinay Prasad MD MPH (@VPrasadMDMPH) June 9, 2023
Guideline | Prevention and therapy of preterm birth
12 Jun, 2023 | 13:45h | UTCPrevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG
SR | Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome
12 Jun, 2023 | 13:41h | UTC
Review | Pregnancy as an early cardiovascular moment: peripartum cardiovascular health
12 Jun, 2023 | 13:36h | UTCPregnancy as an Early Cardiovascular Moment: Peripartum Cardiovascular Health – Circulation Research
Commentary on Twitter
@CircRes Alert! Compendium on Early #CVD#Pregnancy as an Early #Cardiovascular Moment: #Peripartum Cardiovascular Health https://t.co/tqOWn9AU0O
Authored by Drs. @heartdocsadiya, NA Cameron, and KJ Lindley pic.twitter.com/KlOXura8Y2
— Circulation Research (@CircRes) June 10, 2023
Cohort Study | Almost a third of bipolar disorder patients non-adherent to 20% or more of prescriptions
12 Jun, 2023 | 13:29h | UTC
RCT | Multivitamin supplementation may improve memory in aged adults
7 Jun, 2023 | 14:12h | UTCMultivitamin Supplementation Improves Memory in Older Adults: A Randomized Clinical Trial – The American Journal of Clinical Nutrition (link to abstract – $ for full-text)
News Releases:
Multivitamin Improves Memory in Older Adults, Study Finds – Columbia University
Related Research: Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial – Alzheimer’s & Dementia