Family Medicine
Correspondence | Potential “healthy vaccinee bias” in a study of BNT162b2 vaccine against Covid-19
21 Jul, 2023 | 13:43h | UTC
Commentary from the author on Twitter (thread – click for more)
Our correspondence is out in @njem written w @VPrasadMDMPH & Ram Duriseti
We show v strong evidence of healthy vaccinee bias in an Israeli study of Pfizer booster vs covid death, which wasn't disclosed
Could explain ALL reported benefit of the booster?https://t.co/F3WeafvUnw pic.twitter.com/b29YQ0lblh
— Tracy Høeg, MD, PhD (@TracyBethHoeg) July 20, 2023
RCT | MIND diet, a hybrid of Mediterranean and DASH, shows no superiority in preventing cognitive decline
21 Jul, 2023 | 13:38h | UTCTrial of the MIND Diet for Prevention of Cognitive Decline in Older Persons – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Commentary on Twitter
Original Article: Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons https://t.co/ED5Rd6oCTf #AAIC23
— NEJM (@NEJM) July 19, 2023
Phase 2 Trial | Maternal GBS6 vaccine shows promise in infant group B strep prevention
21 Jul, 2023 | 13:34h | UTCCommentary: Maternal strep B vaccine slashes risk of infection among infants – CIDRAP
RCT | Molecular screening for bacterial vaginosis does not significantly reduce preterm birth rates
21 Jul, 2023 | 13:31h | UTCSee also: Visual Abstract
Cohort Study | Bipolar disorder associated with a 6-fold higher mortality risk from external causes
21 Jul, 2023 | 13:29h | UTCNews Release: Bipolar disorder linked to 6-fold heightened risk of early death from external causes – BMJ Newsroom
Systematic Review | Medical treatment of eosinophilic esophagitis
21 Jul, 2023 | 13:27h | UTCMedical treatment of eosinophilic esophagitis – Cochrane Library
Summary: Medical treatments for eosinophilic esophagitis – Cochrane Library
Related:
M-A | Efficacy of elimination diets in eosinophilic esophagitis
RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis
USPSTF Statement | Evidence lacking for lipid disorders screening in asymptomatic children and adolescents
20 Jul, 2023 | 11:13h | UTCEvidence Report: Screening for Lipid Disorders in Children and Adolescents: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Patient Page: Screening for Lipid Disorders in Children and Adolescents – JAMA
Commentary: USPSTF: Screening Kids for Lipid Disorders Still Needs More Data – TCTMD
RCT | Hearing intervention fails to impact 3-year cognitive decline in older adults
20 Jul, 2023 | 11:09h | UTCHearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
#AAIC23 While hearing aids did not have an impact on cognitive decline over 3 years in a general population, treating hearing loss protected against cognitive decline in older adults at greater risk of dementia, finds a new trial: https://t.co/1UjGgDf5m5 pic.twitter.com/kuujeekCWW
— The Lancet (@TheLancet) July 18, 2023
Prospective Study | Intelligence likely remains intact after pediatric concussion
20 Jul, 2023 | 11:06h | UTCIQ After Pediatric Concussion – Pediatrics (free for a limited period)
Commentaries:
IQ After Pediatric Concussion: Clinical Considerations – Pediatrics
No Evidence Seen for Differences in IQ After Pediatric Concussion – HealthDay
Concussions do not affect IQ in children, study finds – News Medical
Systematic Review | Outcomes in deprescribing implementation trials and compliance with expert recommendations
20 Jul, 2023 | 10:55h | UTCRelated:
RCT | Opioids not more effective than placebo for acute low back and neck pain
RCT | A deprescribing intervention reduced medication burden among older adults in post-acute care
Deprescribing proton pump inhibitors – Australian Journal of General Practice
Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports
Deprescribing in Palliative Cancer Care – Life
Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360
Polypharmacy Management in Older Patients – Mayo Clinic Proceedings
Eliminating Medication Overload: A National Action Plan – Lown Institute
Common ED Medication Errors: Polypharmacy – emDocs
Current and future perspectives on the management of polypharmacy – BMC Family Practice
Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international
Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety
Review | Painful diabetic peripheral neuropathy
20 Jul, 2023 | 10:53h | UTC
Self-measured blood pressure telemonitoring programs: a pragmatic how-to guide
19 Jul, 2023 | 14:33h | UTC
Podcast | Hematuria pearls
19 Jul, 2023 | 14:19h | UTC#404 Hematuria with Dr. Derek Fine – The Curbsiders
IARC, WHO agency, identifies aspartame as potentially carcinogenic but probably safe within established acceptable daily intake
18 Jul, 2023 | 13:58h | UTCNews Release: Aspartame hazard and risk assessment results released – World Health Organization
Commentaries:
Expert reaction to IARC and JEFCA summary on aspartame – Science Media Centre
Aspartame Hazard and Risk Assessment Results Released by IARC and JECFA – The ASCO Post
AHA Scientific Statement | Cardiopulmonary impact of electronic cigarettes and vaping products
18 Jul, 2023 | 13:56h | UTCNews Releases:
Top Things to Know: Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products – American Heart Association
Commentary: Vaping’s Risks to CV Health Not Yet Fully Known: AHA – CIDRAP
RCT | Direct oral challenge noninferior to skin testing followed by direct oral challenge in low-risk penicillin allergy patients
18 Jul, 2023 | 13:54h | UTCEfficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
See also: Visual Abstract
News Release: World-first clinical trial to help millions with penicillin allergies – Vanderbilt University Medical Center
Commentary: Trial supports use of direct oral challenge for penicillin allergy – CIDRAP
RCT | Donanemab slows early symptomatic Alzheimer’s progression, but raises serious safety concerns
18 Jul, 2023 | 13:51h | UTCDonanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial – JAMA (free for a limited period)
Editorials:
Donanemab for Alzheimer Disease—Who Benefits and Who Is Harmed? – JAMA (free for a limited period)
Amyloid-Targeting Monoclonal Antibodies for Alzheimer Disease – JAMA (free for a limited period)
Ushering in a New Era of Alzheimer Disease Therapy – JAMA (free for a limited period)
See also: Visual Abstract
Commentary: Expert reaction to results from Eli Lilly on its anti-amyloid drug donanemab – Science Media Centre
Related: RCT | Lecanemab slows cognitive decline in early Alzheimer’s disease but raises safety concerns.
Nationwide Cohort Study | Adolescent hypertension linked with increased stroke risk in young adulthood
18 Jul, 2023 | 13:49h | UTCCommentary: The Relationship Between Adolescent Hypertension and Stroke Risk After Age 40 Years – Neurology Advisor
Guideline | Prevention and management of childhood progressive myopia
18 Jul, 2023 | 13:35h | UTC
RCT | Prostatic artery embolization improves symptoms more than combined medical therapy in BPH patients
18 Jul, 2023 | 13:34h | UTC
Guideline | Antibiotic therapy in patients with suspected antibiotic allergy
17 Jul, 2023 | 13:59h | UTC
Retrospective Analysis | Inconsistencies in pediatric drug dosing found in over half of prehospital emergency drug administrations
17 Jul, 2023 | 13:50h | UTCCommentaries:
Children and Drug Dosing Variations When in Transit to the Hospital – AAP Journals Blog
Variation Seen in Dosing of Meds at Prehospital Pediatric Encounters – HealthDay
M-A | One-year usage of elastic compression stockings comparable to two for post-thrombotic syndrome prevention
17 Jul, 2023 | 13:49h | UTC
Meta-Analysis | Nearly 6% of first-episode psychosis patients exhibit clinically relevant MRI abnormalities
17 Jul, 2023 | 13:32h | UTCNews Release: Routine brain scanning may improve clinical care for people with psychosis – University of Oxford
Cohort Study | Mental disorders linked to increased cardiovascular events in young patients
17 Jul, 2023 | 13:20h | UTCIncreased cardiovascular events in young patients with mental disorders: a nationwide cohort study – European Journal of Preventive Cardiology (free for a limited period)
News Release: Under 40s with mental health problems have elevated risks of heart attack and stroke – European Society of Cardiology