Family Medicine
AGA clinical practice update on evaluation and management of belching, abdominal bloating, and distention
27 Jul, 2023 | 13:04h | UTC
RCT | Zuranolone, a potential rapid-acting oral treatment for severe postpartum depression
27 Jul, 2023 | 13:00h | UTCZuranolone for the Treatment of Postpartum Depression – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Postpartum Depression Pill Zuralonone Shows Promise in Women With Severe Symptoms – Psychiatric News Alert
Related: RCT | Zuranolone outperforms placebo in major depressive disorder treatment
Review | Pediatric-onset inflammatory bowel disease: recent developments
27 Jul, 2023 | 12:57h | UTCInflammatory bowel disease: recent developments – Archives of Disease in Childhood
Podcast | Obesity medicine, GLP1 agonists, weight loss management tools and tips
27 Jul, 2023 | 12:55h | UTC#405 Obesity Medicine, GLP1 agonists, Weight Loss Management Tools and Tips – The Curbsiders
Podcast | Celiac disease pearls
27 Jul, 2023 | 12:53h | UTC#89: Celiac Disease – The Great Mimicker – The Cribsiders
RCT | Pitavastatin effective in the primary prevention of cardiovascular disease in HIV-infected individuals
26 Jul, 2023 | 13:35h | UTCPitavastatin to Prevent Cardiovascular Disease in HIV Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Pitavastatin lowers risk of cardiovascular events in people living with HIV – Aidsmap
Statins reduce cardiovascular risk in people living with HIV, new global study finds – STAT
Pitavastatin Cuts MACE in HIV-Infected Patients: REPRIEVE – TCTMD
Commentary on Twitter
Original Article: Pitavastatin to Prevent Cardiovascular Disease in HIV Infection https://t.co/HuR0Lt24N5
Editorial: HIV and Cardiovascular Disease — An Ounce of Prevention https://t.co/fsxCqrLKi0#IAS2023 pic.twitter.com/TCSQkJQNYa
— NEJM (@NEJM) July 24, 2023
ISCHEMIA Trial 2ry Analysis | Patients with CCD and daily/weekly angina seem to benefit most from complete revascularization
26 Jul, 2023 | 13:33h | UTCComplete Revascularization and Angina-Related Health Status in the ISCHEMIA Trial – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Complete Revascularization and Angina-Related Health Status – American College of Cardiology
More Angina Relief With Complete Revascularization in Stable CAD: ISCHEMIA – TCTMD
Related/Original Articles:
ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease
ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease
Perspective | What does it mean to discover a coronary blockage?
26 Jul, 2023 | 13:31h | UTCChapter 1: What Does it Mean to Discover a Coronary Blockage? – By Dr John Mandrola
Chapter 2: On the meaning of a coronary blockage – By Dr John Mandrola
Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness
26 Jul, 2023 | 13:28h | UTC
Cohort Study | More data suggests SGLT-2 inhibitors could reduce gout flares
26 Jul, 2023 | 13:24h | UTCComparative Effectiveness of Sodium–Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations: A General Population Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
SGLT-2 inhibitors reduced gout flares in patients with diabetes, gout – ACP Internist
SGLT2i Use Linked to Reduced Risk for Flare in Adults With Gout, T2D – HealthDay
SGLT2 inhibitors linked with fewer gout flares in diabetes – MDedge
M-A | Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals
26 Jul, 2023 | 13:15h | UTCCommentary: M-A: Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals – HCP Live
M-A | Oral isotretinoin and triple topical therapies found most effective in acne vulgaris treatment
26 Jul, 2023 | 13:13h | UTC
RCT | Vitamin D supplementation shows no cognitive benefit in mild cognitive impairment intervention
25 Jul, 2023 | 14:00h | UTCCommentary: Exercise and Cognitive Training Slow Thinking Declines. Vitamin D? Not So Much – HealthDay
Related:
RCT | No statistically significant impact of vitamin D on major cardiovascular events
2ry analysis of a RCT | Vitamin D supplementation does not affect cognitive function in older adults
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Cohort Study | BMI of 25.0–29.9 not linked with higher mortality in 21st century U.S. adults
25 Jul, 2023 | 13:58h | UTCNews Release: No increase in mortality for most overweight people, study finds – PLOS
Commentary: Expert reaction to study looking at BMI and all-cause mortality – Science Media Centre
Research Findings | US annual serious harms from misdiagnosis estimated at 795K in recent study
25 Jul, 2023 | 13:57h | UTCBurden of serious harms from diagnostic error in the USA – BMJ Quality & Safety (link to abstract – $ for full-text)
News Release: Report Highlights Public Health Impact of Serious Harms From Diagnostic Error in U.S. – Johns Hopkins Medicine
Commentaries:
Misdiagnoses cost the U.S. 800,000 deaths and serious disabilities every year, study finds – STAT
Global, regional, and national burden of meningitis and its etiologies, 1990–2019
25 Jul, 2023 | 13:55h | UTC
Commentary on Twitter
Although largely preventable, meningitis still causes hundreds of thousands of deaths globally each year.
New @IHME_UW #GBDStudy in @TheLancetNeuro assesses incident cases and deaths due to acute infectious meningitis by aetiology and age from 1990–2019. https://t.co/S3KtMA7DMs pic.twitter.com/AYuSJHsNwK
— The Lancet (@TheLancet) July 20, 2023
Consensus Paper | Urinary tract infections in pregnant individuals
25 Jul, 2023 | 13:53h | UTCUrinary Tract Infections in Pregnant Individuals – Obstetrics & Gynecology
Key factors associated with quality of postnatal care: a pooled analysis of 23 countries
25 Jul, 2023 | 13:50h | UTC
Cohort Study | Association found between carpal tunnel syndrome and heart failure incidence
25 Jul, 2023 | 13:42h | UTCCommentary: Carpal Tunnel Syndrome Again Tied to Heart Failure: German Data – TCTMD
Systematic Review | Existing research on post-stroke depression interventions lacks conclusive results
25 Jul, 2023 | 13:37h | UTC
Systematic Review | Moderate evidence supports interactive mobile phone interventions for contraception use enhancement
25 Jul, 2023 | 13:25h | UTCMobile phone‐based interventions for improving contraception use – Cochrane Library
New WHO guidance on the role of HIV viral suppression in improving individual health and reducing transmission
24 Jul, 2023 | 13:17h | UTCNews Release: New WHO guidance on HIV viral suppression and scientific updates released at IAS 2023 – World Health Organization
WHO Guidance: The role of HIV viral suppression in improving individual health and reducing transmission – Word Health Organization
Related WHO Guidelines:
WHO recommends optimizing HIV testing services – World Health Organization
Primary health care and HIV: convergent actions – World Health Organization
Systematic Review | Low-level HIV viremia (below 1000 copies/mL) linked to minimal sexual transmission risk
24 Jul, 2023 | 13:15h | UTCThe risk of sexual transmission of HIV in individuals with low-level HIV viraemia – The Lancet
Editorial: HIV is sexually untransmittable when viral load is undetectable – The Lancet
Related: Study: Growing Acceptability of “Undetectable = Untransmittable” but Widespread Misunderstanding of HIV Transmission Risk Persists (several texts on the subject)
Commentary on Twitter
People on ART with low but detectible levels of HIV viral load have almost zero risk of sexually transmitting the virus to others, in-depth review suggests #IAS2023https://t.co/wU26C8cEMK pic.twitter.com/hQHLDqPxO6
— The Lancet (@TheLancet) July 22, 2023
RCT | Planned delivery from 34 weeks’ gestation effectively reduces pre-eclampsia related morbidity and mortality in LMICs
24 Jul, 2023 | 13:10h | UTCRelated:
RCT | Planned delivery for pre-eclampsia between 34 and 37 weeks of gestation
M-A | Planned delivery or expectant management in preeclampsia.
Randomized Trial: Planned Early Delivery vs. Expectant Management for Late Preterm Pre-eclampsia
Systematic Review | Insufficient evidence for ACEi/ARB’s impact on early non-diabetic CKD
24 Jul, 2023 | 12:56h | UTC