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Meta-analysis | Even low levels of alcohol consumption may increase blood pressure

2 Aug, 2023 | 14:07h | UTC

Alcohol Intake and Blood Pressure Levels: A Dose-Response Meta-Analysis of Nonexperimental Cohort Studies – Hypertension

News Release: Routinely drinking alcohol may raise blood pressure even in adults without hypertension – AHA Newsroom

 


Evidence Review | AA and other 12-step programs outperform CBT for alcohol use disorder

2 Aug, 2023 | 14:05h | UTC

Alcohol dependence: evidence and experience on 12 steps to recovery – Evidently Cochrane

Original study: Alcoholics Anonymous and other 12‐step programs for alcohol use disorder – Cochrane Library

 


Cohort Study | Depression at any life stage linked to increased dementia incidence

2 Aug, 2023 | 13:49h | UTC

Association of Early-, Middle-, and Late-Life Depression With Incident Dementia in a Danish Cohort – JAMA Neurology (link to abstract – $ for full-text)

Commentary: Depression Over Adulthood May Increase Risk of Dementia – Psychiatric News Alert

 


RCT | Maternal egg intake in early neonatal period does not impact infant egg allergy risk

2 Aug, 2023 | 13:47h | UTC

Effect of Maternal Egg Intake During the Early Neonatal Period and Risk of Infant Egg Allergy at 12 Months Among Breastfeeding Mothers: A Randomized Clinical Trial – JAMA Network Open

See also: Visual Abstract

 


Review | Non-alcoholic fatty liver disease: pathophysiological concepts and treatment options

1 Aug, 2023 | 14:19h | UTC

Non-alcoholic fatty liver disease: pathophysiological concepts and treatment options – Cardiovascular Research

Related:

From NAFLD to MASLD | New consensus changes fatty liver disease terminology to avoid stigmatization

Nonalcoholic fatty liver disease from a primary care perspective – Diabetes, Obesity and Metabolism

AASLD practice guidance on the clinical assessment and management of nonalcoholic fatty liver disease – Hepatology

Management of NAFLD in primary care settings – Liver International

Updated S2k Clinical Practice Guideline on Non-alcoholic Fatty Liver Disease (NAFLD) issued by the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie

AGA Clinical Practice Update | Diagnosis and management of nonalcoholic fatty liver disease in lean individuals.

Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group – The Lancet Gastroenterology & Hepatology (free registration required)

Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association – Arteriosclerosis, Thrombosis, and Vascular Biology

Advancing the global public health agenda for NAFLD: a consensus statement – Nature Reviews Gastroenterology & Hepatology

Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease – Gastroenterology

Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports

 


Cohort Study | History of pregnancy loss linked to higher MI and stroke risk in women, but not in male partners

1 Aug, 2023 | 14:13h | UTC

Pregnancy Loss and the Risk of Myocardial Infarction, Stroke, and All‐Cause Mortality: A Nationwide Partner Comparison Cohort Study – Journal of the American Heart Association

Commentary: Pregnancy Loss Linked to Increased Risk of Heart Attack in Women, But Not Male Partners – HCP Live

 


Review | Vegetarian and vegan diets: benefits and drawbacks

1 Aug, 2023 | 14:11h | UTC

Vegetarian and vegan diets: benefits and drawbacks – European Heart Journal (free for a limited period)

 

Commentary on Twitter

 


Opinion Video | Critical analysis of the data behind Covid-19 booster shots

31 Jul, 2023 | 14:40h | UTC

“FLAWED Booster data was used by FDA for Mass Vax Campaign & We PROVE it in our new PAPER” – YouTube Video by Dr Vinay Prassad

Original Publication: Correspondence | Potential “healthy vaccinee bias” in a study of BNT162b2 vaccine against Covid-19

 


M-A | Various exercise training modes reduce resting blood pressure, isometric exercise most effective

31 Jul, 2023 | 14:35h | UTC

Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials – British Journal of Sports Medicine

News Release: Static isometric exercise, such as wall sits, best for lowering blood pressure – BMJ Newsroom

Commentary: Wall squats and planks best at lowering blood pressure – BBC

 


An ESPGHAN position paper on the diagnosis, management and prevention of cow’s milk allergy

31 Jul, 2023 | 14:28h | UTC

An ESPGHAN position paper on the diagnosis, management and prevention of cow’s milk allergy – Journal of Pediatric Gastroenterology and Nutrition

 


Study | Childhood deaths in high-mortality settings mostly preventable; infection, malnutrition top causes

31 Jul, 2023 | 14:05h | UTC

Causes of Death Among Infants and Children in the Child Health and Mortality Prevention Surveillance (CHAMPS) Network – JAMA Network Open

Invited Commentary: Need for a Structural Approach to Promote Child Survival – JAMA Network Open

News Release: Eight out of ten child deaths in low-income countries could be prevented – Barcelona Institute for Global Health

 


UNESCO calls for global ban on smartphones in schools

28 Jul, 2023 | 14:26h | UTC

Report: Technology in education – UNESCO

News Releases:

UNESCO calls for global ban on smartphones in schools – UN News

Smartphones in school? Only when they clearly support learning – UNESCO

Commentary: ‘Put learners first’: Unesco calls for global ban on smartphones in schools – The Guardian

 


WHO updates guidelines on fats and carbohydrates

28 Jul, 2023 | 14:25h | UTC

News Release: WHO updates guidelines on fats and carbohydrates – World Health Organization

Guidelines:

Saturated fatty acid and trans-fatty acid intake for adults and children: WHO guideline – World Health Organization

Total fat intake for the prevention of unhealthy weight gain in adults and children: WHO guideline – World Health Organization

Carbohydrate intake for adults and children: WHO guideline – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


Study | Only 11% of sports supplements listing botanical ingredients accurately declare contents, 12% contain FDA-prohibited stimulants

28 Jul, 2023 | 14:21h | UTC

Presence and Quantity of Botanical Ingredients With Purported Performance-Enhancing Properties in Sports Supplements – JAMA Network Open

Commentaries:

Ensuring the Safety and Value of Supplements – JAMA Network Open

Sports Supplements Can Be Contaminated with Botanical Stimulants and Anabolic Agents – NEJM Journal Watch

 


Position Paper | Prioritizing deprescribing in fall prevention strategies

28 Jul, 2023 | 14:12h | UTC

European position paper on polypharmacy and fall-risk-increasing drugs recommendations in the World Guidelines for Falls Prevention and Management: implications and implementation – European Geriatric Medicine

Original Guideline: World guidelines for falls prevention and management for older adults: a global initiative – Age and Ageing

 


Cohort Study | Exploring the potential impact of artificial sweeteners on type 2 diabetes risk

28 Jul, 2023 | 14:07h | UTC

Artificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Santé Cohort – Diabetes Care

 


RCT | Liraglutide aids weight management in patients with suboptimal weight loss post metabolic surgery

28 Jul, 2023 | 14:05h | UTC

Safety and Efficacy of Liraglutide, 3.0 mg, Once Daily vs Placebo in Patients With Poor Weight Loss Following Metabolic Surgery: The BARI-OPTIMISE Randomized Clinical Trial – JAMA Surgery

See also: Visual Abstract

 


WHO world drowning prevention day 2023

27 Jul, 2023 | 13:12h | UTC

World Drowning Prevention Day 2023 – World Health Organization

Report: Hidden depths: the global investment case for drowning prevention – World Health Organization

Related:

Wilderness Medical Society Clinical Practice Guidelines for the Treatment and Prevention of Drowning: 2019 Update

Tracing the emergence of drowning prevention on the global health and development agenda: a policy analysis – The Lancet Global Health

WHO Guideline on the prevention of drowning through provision of day-care and basic swimming and water safety skills – World health Organization

Wilderness Medical Society Clinical Practice Guidelines for the Treatment and Prevention of Drowning: 2019 Update

Prevention of Drowning – Pediatrics

The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study – Injury Prevention

Preventing drowning: an implementation guide – World Health Organization

Global report on drowning: preventing a leading killer – World Health Organization

Hidden Hazards: An Exploration of Open Water Drowning and Risks for Children – Safe Kids Worldwide

 

Commentary on Twitter (thread – click for more)

 


RCT – 2ry Analysis | Elevated intracranial bleeding risk with low-dose aspirin in older adults

27 Jul, 2023 | 13:09h | UTC

Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People: Secondary Analysis of a Randomized Clinical Trial – JAMA Network Open

See also: Visual Abstract

News Release: Low dose aspirin won’t help some older adults trying to avoid a stroke: study – Monash University

Commentary: Daily aspirin doesn’t prevent strokes in older, healthy people after all – The Conversation

Original Study: Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Guideline: USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

#347 USPSTF Update: Aspirin for Primary Prevention of CVD – The Curbsiders

 


RCT | Limited antibiotic efficacy in children with sinusitis lacking nasopharyngeal pathogens

27 Jul, 2023 | 13:08h | UTC

Identifying Children Likely to Benefit From Antibiotics for Acute Sinusitis: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Acute Bacterial Sinusitis: Limitations of Test-Based Treatment – JAMA (free for a limited period)

News Release: Bacterial testing in kids with sinusitis could slash antibiotic use – University of Pittsburgh

Commentary: Trial suggests bacterial test could reduce antibiotics in kids with sinusitis – CIDRAP

 

Commentary on Twitter

 


RCT | Cervical pessary fails to prevent preterm birth in short cervix singleton pregnancies

27 Jul, 2023 | 13:06h | UTC

Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix: The TOPS Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: The Vexing Problem of Preterm Birth Prevention – JAMA (free for a limited period)

See also: Visual Abstract

News Release: Cervical pessary no more effective than usual care in preventing preterm birth risk – NIH News Releases

 


AGA clinical practice update on evaluation and management of belching, abdominal bloating, and distention

27 Jul, 2023 | 13:04h | UTC

AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review – Gastroenterology

 


RCT | Zuranolone, a potential rapid-acting oral treatment for severe postpartum depression

27 Jul, 2023 | 13:00h | UTC

Zuranolone for the Treatment of Postpartum Depression – American Journal of Psychiatry (link to abstract – $ for full-text)

Commentary: Postpartum Depression Pill Zuralonone Shows Promise in Women With Severe Symptoms – Psychiatric News Alert

Related: RCT | Zuranolone outperforms placebo in major depressive disorder treatment

 


Review | Pediatric-onset inflammatory bowel disease: recent developments

27 Jul, 2023 | 12:57h | UTC

Inflammatory bowel disease: recent developments – Archives of Disease in Childhood

 


Podcast | Obesity medicine, GLP1 agonists, weight loss management tools and tips

27 Jul, 2023 | 12:55h | UTC

#405 Obesity Medicine, GLP1 agonists, Weight Loss Management Tools and Tips – The Curbsiders

 


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