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NEWS - Family Medicine

Alex Nowbar’s weekly research reviews, 3 December 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Medical Screening Tests You Do and Don’t Need – Consumer Reports (free) (via @EricTopol)

“Some may be life-saving, but others can waste time and money—and pose risks”

 


Fluoroquinolones and the risk of aortopathy: A systematic review and meta-analysis – International Journal of Cardiology (free)

“…current fluoroquinolone use was significantly associated with increased risk of aortic aneurysm and dissection.”

 


Ann Robinson’s research reviews, 26 November 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Cannabinoids for Chronic Pain – Therapeutics Initiative (free)

Related: Meta-Analysis: Cannabinoids for the Treatment of Chronic Noncancer Pain Conditions (free) AND Guideline for Prescribing Medical Cannabinoids in Primary Care (free article and commentary)

“At the present time we lack good evidence that any cannabis-derived product works for chronic pain”

 


Abraar Karan: Has the physical exam had its day? – The BMJ Opinion (free)

“Seeing patients in clinic today, I know that putting my stethoscope on them has a therapeutic effect, even if as their doctor, I am quite certain their heart and lungs are normal. However, this doesn’t mean the physical exam should not evolve.” (via @AbraarKaran see Tweet)

 


Antipsychotic drug use and pneumonia: Systematic review and meta-analysis – Journal of Psychopharmacology (link to abstract – $ for full-text)

Commentary: Antipsychotics May Increase Risk of Pneumonia, Meta-Analysis Suggests – Psychiatric News Alert (free)

“Although antipsychotic use was associated with a higher risk of pneumonia, the researchers stopped short of claiming causality, citing a lack of data from randomized, controlled trials and a failure of observational studies to control for relevant confounders like tobacco use and weight.” (from Psychiatric News Alert)

 


Alex Nowbar’s research reviews, 12 November 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Risk of Malignant Ovarian Cancer Based on Ultrasonography Findings in a Large Unselected Population – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Most simple ovarian cysts require no treatment, surveillance – UPI (free) AND Less surveillance needed for simple ovarian cysts – University of California, San Francisco (free)

“New study finds that simple cysts should be considered normal and ignored” (from The University of California)

 


Perioperative alcohol cessation intervention for postoperative complications – Cochrane Library (free)

Summary: Effects of perioperative alcohol cessation interventions on postoperative complications following surgery – Cochrane Library (free)

“Intensive alcohol cessation interventions offered for four to eight weeks to participants undergoing all types of surgical procedures to achieve complete alcohol cessation before surgery probably reduced the number of postoperative complications.”

 


A Profusion of Diagnoses. That’s Good and Bad – The New York Times (10 articles per month are free)

“…we may also be medicalizing much of normal human behavior — labeling the healthy as diseased, and exposing them to undue risk of stigma, testing and treatment.”

 


Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: Systematic review and meta-analysis – The Journal of Infection (free)

“A number of symptoms and signs typically associated with UTI, such as nocturia, urgency and abnormal vital signs, were of limited use in older adult outpatients.”

 


Ann Robinson’s weekly research reviews, 5 November 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) – Cochrane Library (free)

Summary: Preventative antibiotic therapy for people with COPD – Cochrane Library (free)

“Use of continuous and intermittent prophylactic antibiotics results in a clinically significant benefit in reducing exacerbations in COPD patients.”

 



Alex Nowbar’s research reviews, 29 October 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis – The BMJ (free)

“Using the adjuvant recombinant subunit vaccine might prevent more cases of herpes zoster than using the live attenuated vaccine, but the adjuvant recombinant subunit vaccine also carries a greater risk of adverse events at injection sites.”

 


Association of Blood Pressure Measurements With Peripheral Artery Disease Events: Reanalysis of the ALLHAT Data – Circulation (free)

Editorial: New Curveball for Hypertension Guidelines? Blood Pressure Targets in Peripheral Artery Disease (free)

“we found a higher rate of lower extremity PAD events with higher and lower SBP and pulse pressure and with lower DBP.”

 


The Problem With Probiotics – The New York Times (free)

Related: Probiotic Safety—No Guarantees (free perspective)

“There are potential harms as well as benefits, and a lot of wishful thinking and imprecision in the marketing of products containing them.”

 


Order Wisely®: Appropriate use of tests & treatments – High Value Practice Academic Alliance (free) (via @KariTikkinen)

Comprehensive educational program that reviews appropriate use of imaging exams, lab tests, medications, transfusions and procedures to promote high-value practice.

 


Alex Nowbar’s research reviews—22 October 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial – The Lancet (free)

Invited Commentary: Steroid injection or wrist splint for first-time carpal tunnel syndrome? (free)

“A single corticosteroid injection shows superior clinical effectiveness at 6 weeks compared with night-resting splints, making it the treatment of choice for rapid symptom response in mild or moderate carpal tunnel syndrome presenting in primary care.”

 


Prokinetics for functional dyspepsia – Cochrane Library (free)

Summary: Medications which promote stomach movement to relieve upper abdominal discomfort that does not have a specific cause – Cochrane Library (free)

“we are unable to say whether prokinetics are effective for the treatment of functional dyspepsia.”

 


Dietary modifications for infantile colic – Cochrane Library (free)

Summary: Diet changes for infant colic – Cochrane Library (free)

“Based on available evidence, we are unable to recommend any intervention”

 


Ann Robinson’s research reviews, 15 October 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Shingrix: A New Vaccine for Shingles – Therapeutics Initiative (free)

“Need to vaccinate 31 people to prevent one instance of HZ; Need to vaccinate 358 people to prevent one instance on post herpetic neuralgia” (via @amtejani)

 


Nine ways research could save the NHS money – NHS Dissemination Centre (free)

New infographic series with selected NIHR Signals covering a range of treatments and initiatives that are cost effective.

 


Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women – Cochrane Library (free)

“Based on the data available, we can be confident that pelvic floor muscle training can cure or improve symptoms of stress urinary incontinence and all other types of urinary incontinence”

 


Zackary Berger’s journal reviews, 8 October 2018 – The BMJ Opinion (free)

Zackary Berger reviews the latest research from the top medical journals.

 


What the tests don’t show – The Washington Post (a few articles per month are free)

“Many doctors are surprisingly bad at reading test results and/or fail to grasp how false positives work. This is putting patients at risk” (via @pash22 see Tweet)

 


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