Family Medicine

Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”

 


Top 10 Medical Myths, Busted

11 Jun, 2019 | 03:31h | UTC

Top 10 medical myths, busted – ACP Internist (free)

“Ten medical myths persist despite all the evidence.”

 


Ann Robinson’s journal review, 5 June 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Prevalence and Cost of Care Cascades After Low-Value Preoperative Electrocardiogram for Cataract Surgery in Fee-for-Service Medicare Beneficiaries – JAMA Internal Medicine (free for a limited period)

Commentary: Cascades Of Care – American Council on Science and Health (free)

Related: Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery (link to abstract and commentary) AND Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery (free)

 

Related Commentary on Twitter (thread – click for more)

 


Association of Preterm Birth With Risk of Ischemic Heart Disease in Adulthood – JAMA Pediatrics (free for a limited period)

Editorial: Cardiovascular Risk in Adults Born Preterm: Time to Act (free for a limited period)

Commentary: Preemies and early arrivals have higher risk of heart disease as adults – Reuters (free)

 

Related Commentary on Twitter

 


Review: Menopausal Hormone Therapy

31 May, 2019 | 06:30h | UTC

Menopausal Hormone Therapy – JAMA (free for a limited period)

Podcast: Menopausal Hormone Therapy (free audio)

 


Tramadol for osteoarthritis – Cochrane Library (free)

Summary: Tramadol for osteoarthritis – Cochrane Library (free)

“tramadol alone or in combination with acetaminophen probably has no important benefit on mean pain or function in people with osteoarthritis, although slightly more people in the tramadol group report an important improvement”

 


Alex Nowbar’s journal reviews, 29 May 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology (free for a limited period)

Related: Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)

 

Related Commentary on Twitter

 



Choosing Wisely Canada-Top Five List in Hepatology: Official Position Statement of the Canadian Association for the Study of the Liver (CASL) and Choosing Wisely Canada (CWC) – Annals of Hepatology (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

1 – Don’t order serum ammonia to diagnose or manage hepatic encephalopathy (HE).

2 – Don’t routinely transfuse fresh frozen plasma, platelets or give Vitamin K to reverse abnormal tests of coagulation in patients with cirrhosis prior to abdominal paracentesis, endoscopic variceal band ligation, or any other minor invasive procedures.

3 – Don’t order HFE genotyping based on serum ferritin values alone to diagnose hereditary hemochromatosis.

4 – Don’t perform computed tomography (CT) or magnetic resonance imaging (MRI) routinely to monitor benign focal liver lesions (ex. focal nodal hyperplasia, hemangioma).

5 – Don’t repeat hepatitis C viral load testing in an individual who has established chronic infection, outside of antiviral treatment.

(Under a Creative Commons license)

 


Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Treatment Changes for Mild Asthma? – NEJM Journal Watch (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

 


Normal Body Temperature: A Systematic Review – Open Forum Infectious Diseases (free)

See also: Interest “Tweetorial” about the definition of a fever (thread)

Related Commentary on Twitter

 


Chronic use of tramadol after acute pain episode: cohort study – The BMJ (free)

Commentaries: Risk of Prolonged Use With Tramadol vs Other Short Acting Opioids Examined – MPR (free) AND ‘There really is no safe opioid’: Study finds tramadol isn’t a less addictive painkiller – CBC (free)

 

Related Commentary on Twitter

 


Alex Nowbar’s journal reviews, 14 May 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Estimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies: A Cost-effectiveness Analysis – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Screening Options for Preventing Cervical Cancer (free for a limited period)

Author Interview: Estimated Quality of Life and Economic Outcomes Associated With Cervical Cancer Screening (free audio)

“Cytologic testing every 3 years and low-cost high-risk human papillomavirus testing every 5 years both may be considered reasonable cervical cancer screening options.”

 

Related Commentary on Twitter

 


Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes – JAMA (free for a limited period)

Editorial: Prepregnancy Body Mass Index, Weight Gain During Pregnancy, and Health Outcomes (free for a limited period)

“Optimal gestational weight gain ranges were 14.0 kg to less than 16.0 kg for women categorized as underweight; 10.0 kg to less than 18.0 kg for normal weight; 2.0 kg to less than 16.0 kg for overweight; 2.0 kg to less than 6.0 kg for obesity grade 1; weight loss or gain of 0 kg to less than 4.0 kg for obesity grade 2; and weight gain of 0 kg to less than 6.0 kg for obesity grade 3.”

 


Review: Chronic Constipation

2 May, 2019 | 04:31h | UTC

Chronic Constipation – Mayo Clinic Proceedings (free)

Related: Indian Consensus on Chronic Constipation in Adults (free guidelines and reviews on the subject)

 


Colorectal Cancer Screening – JAMA (free for a limited period)

Related: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)

 


Clinical Update: Metformin in 2019

23 Apr, 2019 | 01:50h | UTC

Metformin in 2019 – JAMA (free for a limited period)

 


Measles cases are up nearly 300% from last year. This is a global crisis – CNN (free)

WHO Statement: New measles surveillance data for 2019 – World Health Organization (free)

By Henrietta H Fore (executive director of UNICEF) and Tedros Adhanom Ghebreyesus (director general of the World Health Organization).

 


Proposal: Reforming disease definitions: a new primary care led, people-centred approach – BMJ Evidence Based Medicine (free)

Commentary: We need new rules for defining who is sick. Step 1: remove vested interests – The Conversation (free)

 

Related Commentary on Twitter

 


Ann Robinson’s research reviews, 9 April 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


BMJ Review: Depression in Primary Care

9 Apr, 2019 | 02:11h | UTC

State of the Art Review: Depression in primary care: part 1—screening and diagnosis – The BMJ (free for a limited period)

Depression in primary care: part 2—management

 

Related Commentary on Twitter

 


Use of vitamin D drops leading to kidney failure in a 54-year-old man – Canadian Medical Association Journal (free)

“Vitamin D toxicity is rare, but clinicians must be aware of the risks of vitamin D use to limit complications related to hypercalcemia”.

 


Review article: treatment options for functional dyspepsia – Alimentary Pharmacology and Therapeutics (free)

“None of the available therapies is effective in the majority of patients without being associated with major side effects.”

 


Ann Robinson’s weekly research reviews, 2 April 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Alex Nowbar’s research reviews, 26 March 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.