Free Online Course: Epidemiology in Public Health Practice

21Aug
2017

Too much medicine: Mapping the drivers of overdiagnosis to potential solutions

17Aug
2017

Too Many Drug Trials, Too Few Patients

17Aug
2017

Assessing the impact of healthcare research

17Aug
2017

Bored reading science? Let’s change how scientists write

16Aug
2017

Bored reading science? Let’s change how scientists write – The Conversation (free) (RT @Onisillos see Tweet)

“Science communicators, journalists, entrepreneurs, policymakers and interested members of the general public are all motivated to follow the latest scientific research. And yet, strangely enough, science papers are a communication tool but they are not that effective at communication”.

 

The Future of Peer Review

16Aug
2017

The Future of Peer Review – Scientific American (free)

“It’s very far from perfect, but major changes for the better are underway”

 

3 reasons why you should be suspicious of study ‘subgroup’ results

15Aug
2017

Richard Lehman’s journal review, 14 August 2017

15Aug
2017

8 – Richard Lehman’s journal review, 14 August 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals

 

Free Online Course: Understanding Clinical Research: Behind the Statistics

14Aug
2017

Free Online Course: Design and Interpretation of Clinical Trials

14Aug
2017

Tools to improve reporting of patient and public involvement in research

11Aug
2017

These People Are Trying To Fix A Huge Problem In Science

11Aug
2017

These People Are Trying To Fix A Huge Problem In Science – BuzzFeed News (free)

“Big, important findings of previous studies – things we thought we knew – have failed to stand up to scrutiny”… (RT @Students4BE see Tweet)

 

Is blogging or tweeting about research papers worth it?

10Aug
2017

Half of papers searched for online are free to read

9Aug
2017

Half of papers searched for online are free to read – Nature News (free)

“Large study of open research analysed reader data from Unpaywall tool, which finds freely available versions of articles”.

 

Richard Lehman’s journal review, 7 August 2017

7Aug
2017

Richard Lehman’s journal review, 7 August 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

 

Evidence for Health Decision Making: Beyond Randomized, Controlled Trials

3Aug
2017

What is a pilot study?

3Aug
2017

A surprising amount of medical research isn’t made public. That’s dangerous

1Aug
2017

A surprising amount of medical research isn’t made public. That’s dangerous – VOX (free)

“When the results of clinical trials aren’t made public, the consequences can be dangerous — and potentially deadly” (RT @Students4BE see Tweet)

 

What a nerdy debate about p-values shows about science

1Aug
2017

The history and development of N of 1 trials

1Aug
2017

Richard Lehman’s journal review, 31 July 2017

1Aug
2017

Richard Lehman’s journal review, 31 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

 

Hope may lead to unrealistic expectations

28Jul
2017

Opinion: Peer review is a black box. Let’s open it up

28Jul
2017

How to advise a friend frightened by a medical headline?

27Jul
2017

Big names in statistics want to shake up much-maligned P value

27Jul
2017

Big names in statistics want to shake up much-maligned P value – Nature News (free)

“One of scientists’ favorite statistics — the P value — should face tougher standards, say leading researchers”

 

Sharing Knowledge for Health Care

25Jul
2017

Richard Lehman’s journal review – 24 July 2017

25Jul
2017

Richard Lehman’s journal review, 24 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

 

Conducting a systematic literature search

23Jul
2017

Surrogate endpoints in oncology: when are they acceptable for regulatory and clinical decisions, and are they currently overused?

23Jul
2017

More is not necessarily better

23Jul
2017

Important considerations when reading research papers

22Jul
2017

Cocoa and blood pressure: food for thought – Evidently Cochrane (free)

Important considerations when reading research papers.

 

How to design efficient cluster randomised trials

18Jul
2017

Research Methods & Reporting: How to design efficient cluster randomised trials – The BMJ (free)

 

When are randomised trials unnecessary? Picking signal from noise

18Jul
2017

A brief history of clinical evidence updates and bibliographic databases

18Jul
2017

Richard Lehman’s weekly review

18Jul
2017

Richard Lehman’s journal review, 17 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

 

How to spot a misleading graph

17Jul
2017

How to spot a misleading graph, by Lea Gaslowitz – TED Talks (free YouTube video)

“How to spot a misleading graph – Great video by Lea Gaslowitz @TEDTalks” (RT @CochraneUK see Tweet)

 

The hidden truth about our prescription medications

16Jul
2017

The hidden truth about our prescription medications – Ideas.Ted.Com (free)

“Uncovering the tale of hidden clinical trial data on prescription drugs” (RT @CebmOxford see Tweet) AND “Around half of the clinical trials that were done on the medicines we use today have never published their results…” (RT @Students4BE see Tweet)

 

Using systematic reviews to reduce research waste

11Jul
2017

Is a chart lying to you? This video has some tips to figure it out

11Jul
2017

Is a chart lying to you? This video has some tips to figure it out. – VOX (free text and video)

“Graphs are supposed to distill complex information. But sometimes they can mislead…” (RT @Students4BE see Tweet)

 

Shared Decision Making: The Importance of Diagnosing Preferences

11Jul
2017

Richard Lehman’s journal review / 10 July 2017

10Jul
2017

Richard Lehman’s journal review / 10 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals

 

Beware of conflicting interests

10Jul
2017

Expert opinion is not always right

8Jul
2017

Master Protocols to Study Multiple Therapies, Multiple Diseases, or Both

7Jul
2017

5 Tips for Understanding Data in Meta-Analyses

5Jul
2017

CONSORT 2010 statement: extension checklist for reporting within person randomised trials

4Jul
2017

Research Methods & Reporting: CONSORT 2010 statement: extension checklist for reporting within person randomised trials – The BMJ (free)

“This document presents the CONSORT extension to within person trials. It aims to facilitate the reporting of these trials. It extends 16 items of the CONSORT 2010 checklist and introduces a modified flowchart and baseline table to enhance transparency”.

 

Fears over a medical gold rush in cancer drug race

4Jul
2017

Fears over a medical gold rush in cancer drug race – Financial Times (a few articles per month are free)

Source: Nature Newsletter

“With almost 800 trials under way observers warn scientific rigour is being compromised”

 

How good is the evidence to support primary care practice?

3Jul
2017

Richard Lehman’s weekly review of medical journals

3Jul
2017

Richard Lehman’s journal review, 3 July 2017 – The BMJ Blogs (free)

Richard Lehman’s weekly review of medical journals.

 

Newer is not necessarily better

3Jul
2017

Living Systematic Reviews are going live

2Jul
2017

Living Systematic Reviews are going live – Cochrane UK (free) (RT @CochraneUK see Tweet)

Related: Living Systematic Reviews – Cochrane Community (free)

“Living Systematic Review is a “systematic review which is continually updated, incorporating relevant new evidence as it becomes available”.

 

Judging the benefits and harms of medicines

30Jun
2017

Editorial: Judging the benefits and harms of medicines – The BMJ (free for 15 days)

“Please read/comment on our editorial @bmj_latest about @acmedsci report on judging benefits and harms of medicines” (RT @fgodlee see Tweet)

 

Common practice is not always evidence-based

30Jun
2017

Association is not the same as causation

30Jun
2017

Websites offering pirated papers are shaking up science

30Jun
2017

Last Month in Oncology with Dr. Bishal Gyawali

30Jun
2017

Last Month in Oncology with Dr. Bishal Gyawali: June 2017 – ecancer News (free)

“New edition of my blogs @ecancer is out focusing on studies presented at #ASCO17 (RT @oncology_bg see Tweet)

 

‘Exaggerations’ threaten public trust in science, says leading statistician

29Jun
2017

Is the staggeringly profitable business of scientific publishing bad for science?

29Jun
2017

Blinding: A detailed guide for students

27Jun
2017

Blinding: A detailed guide for students – Students 4 Best Evidence (free)

“New @Students4BE blog: Saul provides a detailed overview of ‘blinding’ in RCTs. What is it & why is it important?” (RT @CochraneUK see Tweet)

 

Richard Lehman’s journal review, 26 June 2017

26Jun
2017

Richard Lehman’s journal review, 26 June 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals

 

Chinese courts call for death penalty for researchers who commit fraud

25Jun
2017

Better Medicine – Shared decisions, best evidence

23Jun
2017

Better Medicine – Shared decisions, best evidence

Related article: Overdiagnosis and overtreatment: generalists — it’s time for a grassroots revolution (free)

“This Better Medicine resource page builds on the work of The BMJ’s Too Much Medicine initiative and the overdiagnosis group of the RCGP in helping health professionals worldwide to share knowledge with patients and jointly make better informed choices about their care.

 

Why We Overrate the Lifesaving Power of Cancer Tests

23Jun
2017

Conflicts of interest in healthcare, academics, public relations and journalism

21Jun
2017

Richard Lehman’s weekly review of medical journals

20Jun
2017

Eight Tips for using Twitter during health-related conferences

19Jun
2017

New science data-sharing rules are two scoops of disappointment

19Jun
2017

Challenges in Opening and Enrolling Patients in Clinical Trials

16Jun
2017

Anecdotes are unreliable evidence

16Jun
2017

Treatments can harm

16Jun
2017

Machine Learning Versus Standard Techniques for Updating Searches for Systematic Reviews

16Jun
2017

Machine Learning Versus Standard Techniques for Updating Searches for Systematic Reviews: A Diagnostic Accuracy Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Artificial intelligence may help doctors keep up with new research – Reuters (free)

“Machine-learning fed by citations of a systematic saved a ton of time for updating it, didn’t miss important studies” (RT @hildabast see Tweet)

 

Number needed to treat (NNT) in clinical literature

13Jun
2017

A real-world approach to Evidence-Based Medicine in general practice

13Jun
2017

Dozens of recent clinical trials may contain wrong or falsified data

7Jun
2017

Data Sharing Statements for Clinical Trials

7Jun
2017

Multiple outcomes and analyses in clinical trials create challenges for interpretation and research synthesis

7Jun
2017

Multiple outcomes and analyses in clinical trials create challenges for interpretation and research synthesis – Journal of Clinical Epidemiology (free)

“RCTs included hundreds of outcomes and results; a small proportion were in public reports. Trialists and meta-analysts may cherry-pick what they report from multiple sources of RCT information.” (RT @hildabast see Tweet)

 

A manifesto for reproducible Science

4Jun
2017

Health Policy Trials

2Jun
2017

Research transparency: 5 questions about open science answered

2Jun
2017

Science Needs a Solution for the Temptation of Positive Results

30May
2017

Diagnosis creep: the new problem in medicine

30May
2017

What is a Systematic Review?

30May
2017

Updated tutorial: What is a Systematic Review? – PubMed Health (free) (RT @hildabast)

 

Joint statement on public disclosure of results from clinical trials – World Health Organization

19May
2017

Joint statement on public disclosure of results from clinical trials – World Health Organization (free)

News release: Major research funders and international NGOs to implement WHO standards on reporting clinical trial results (free)

Commentary: Industry leaders agree to implement UN agency’s standards on clinical trial reporting – United Nations News Centre (free)

“Funders of medical research & international NGOs to implement WHO standards on reporting clinical trial results”. “Today, on average 50% of Clinical Trials go unreported, according to several studies, often because the results are negative”. “Unreported trial results leave an incomplete & potentially misleading picture of the risks & benefits of vaccines, drugs and medical devices” (see Tweets)

 

How to rein in the widening disease definitions that label more healthy people as sick

17May
2017

Countering cognitive biases in minimizing low value care

12May
2017

Review: Countering cognitive biases in minimizing low value care – The Medical Journal of Australia (free)

“How cognitive bias affects clinical decision making and what to do about it. Well written & useful” (RT @carissa_bon and @JulieLeask see Tweet)

 

Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today

6May
2017

Research letter: Applicability of the IMPROVE-IT Trial to Current Patients With Acute Coronary Syndrome – JAMA Internal Medicine (link to abstract – $ for full text)

Source: Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today (free registration required)

Related: Exclusion of patients with concomitant chronic conditions in ongoing randomised controlled trials targeting 10 common chronic conditions and registered at ClinicalTrials.gov: a systematic review of registration details – BMJ Open (free) AND Do cancer clinical trials exaggerate the real-world benefits of drugs? – STAT News (free)

Patients in clinical trials are often younger, healthier (with less comorbidities), better plugged in to the health care system, better educated and wealthier, indicating that the external validity or generalizability of much of the current evidence to real-world settings may be relatively weak.

 

As scientists take to Twitter, study shows power of ‘visual abstract’ graphics

4May
2017

Statistical significance vs. clinical significance

24Apr
2017

Too many studies have hidden conflicts of interest. A new tool makes it easier to see them

21Apr
2017

Too many studies have hidden conflicts of interest. A new tool makes it easier to see them – VOX (free)

“Great news: PubMed is finally publishing info about funding sources/conflicts of interest on its abstracts” (RT @paimadhu and @juliaoftorontosee Tweet)

 

Initiative aims to break science’s citation paywall

7Apr
2017

Unlocking paywalled research papers (legally)

6Apr
2017

Unpaywall finds free versions of paywalled papers – Nature (free) (RT @dannykay68)

See also: Unlocking paywalled research papers: Two big steps forward, two steps back, by James C Coyne – Coyne of the Realm (RT @hildabast)

Apparently, it successfully finds an open-access version (completely legal) of a paper around 30% of the time. We have tried and it worked for some of the articles we’ve tested. See it for yourself.

 

To Screen or not to Screen?

4Apr
2017

Science papers are getting harder to read

4Apr
2017

The seven deadly sins of statistical misinterpretation

31Mar
2017

Exposing peer review

30Mar
2017

Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation

30Mar
2017

Regression to the mean, and its importance in healthcare decisions

29Mar
2017

Regression to the mean, or why perfection rarely lasts – The Conversation (free) (RT @PaulGlasziou)

“Regression to the mean, and its importance in healthcare decisions” (RT @Tammy_Hoffmann see Tweet)

 

Richard Lehman’s weekly review

28Mar
2017

Gates Foundation announces open-access publishing venture

27Mar
2017
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