Open access
Open access
Powered by Google Translator Translator

Endocrinology (all articles)

RCT | Liraglutide aids weight management in patients with suboptimal weight loss post metabolic surgery

28 Jul, 2023 | 14:05h | UTC

Safety and Efficacy of Liraglutide, 3.0 mg, Once Daily vs Placebo in Patients With Poor Weight Loss Following Metabolic Surgery: The BARI-OPTIMISE Randomized Clinical Trial – JAMA Surgery

See also: Visual Abstract

 


RCT – 2ry Analysis | Elevated intracranial bleeding risk with low-dose aspirin in older adults

27 Jul, 2023 | 13:09h | UTC

Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People: Secondary Analysis of a Randomized Clinical Trial – JAMA Network Open

See also: Visual Abstract

News Release: Low dose aspirin won’t help some older adults trying to avoid a stroke: study – Monash University

Commentary: Daily aspirin doesn’t prevent strokes in older, healthy people after all – The Conversation

Original Study: Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Guideline: USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

#347 USPSTF Update: Aspirin for Primary Prevention of CVD – The Curbsiders

 


Scientific Statement | Addressing childhood obesity to reduce adult CV risk through lifestyle

27 Jul, 2023 | 13:03h | UTC

Lifestyle interventions to change trajectories of obesity-related cardiovascular risk from childhood onset to manifestation in adulthood: a joint scientific statement of the task force for childhood health of the European Association of Preventive Cardiology and the European Childhood Obesity Group – European Journal of Preventive Cardiology

News Release: How to stop obese children having heart disease in adulthood – European Society of Cardiology

 


Podcast | Obesity medicine, GLP1 agonists, weight loss management tools and tips

27 Jul, 2023 | 12:55h | UTC

#405 Obesity Medicine, GLP1 agonists, Weight Loss Management Tools and Tips – The Curbsiders

 


RCT | Pitavastatin effective in the primary prevention of cardiovascular disease in HIV-infected individuals

26 Jul, 2023 | 13:35h | UTC

Pitavastatin to Prevent Cardiovascular Disease in HIV Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Pitavastatin lowers risk of cardiovascular events in people living with HIV – Aidsmap

Statins reduce cardiovascular risk in people living with HIV, new global study finds – STAT

Pitavastatin Cuts MACE in HIV-Infected Patients: REPRIEVE – TCTMD

 

Commentary on Twitter

 


Cohort Study | More data suggests SGLT-2 inhibitors could reduce gout flares

26 Jul, 2023 | 13:24h | UTC

Comparative Effectiveness of Sodium–Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations: A General Population Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries:

SGLT-2 inhibitors reduced gout flares in patients with diabetes, gout – ACP Internist

SGLT2i Use Linked to Reduced Risk for Flare in Adults With Gout, T2D – HealthDay

SGLT2 inhibitors linked with fewer gout flares in diabetes – MDedge

 


M-A | Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals

26 Jul, 2023 | 13:15h | UTC

Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular Disease: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: M-A: Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals – HCP Live

 


RCT | Vitamin D supplementation shows no cognitive benefit in mild cognitive impairment intervention

25 Jul, 2023 | 14:00h | UTC

Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial – JAMA Network Open

Commentary: Exercise and Cognitive Training Slow Thinking Declines. Vitamin D? Not So Much – HealthDay

Related:

RCT | No statistically significant impact of vitamin D on major cardiovascular events

2ry analysis of a RCT | Vitamin D supplementation does not affect cognitive function in older adults

RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

 


Cohort Study | BMI of 25.0–29.9 not linked with higher mortality in 21st century U.S. adults

25 Jul, 2023 | 13:58h | UTC

Body mass index and all-cause mortality in a 21st century U.S. population: A National Health Interview Survey analysis – PLOS One

News Release: No increase in mortality for most overweight people, study finds – PLOS

Commentary: Expert reaction to study looking at BMI and all-cause mortality – Science Media Centre

 


Guideline | Laboratory analysis in the diagnosis and management of diabetes mellitus

21 Jul, 2023 | 13:50h | UTC

Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus – Diabetes Care

Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus – Diabetes Care

 


USPSTF Statement | Evidence lacking for lipid disorders screening in asymptomatic children and adolescents

20 Jul, 2023 | 11:13h | UTC

Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement – JAMA

Evidence Report: Screening for Lipid Disorders in Children and Adolescents: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Editorial: Still “on the Fence” About Universal Childhood Lipid Screening: The USPSTF Reaffirms an I Statement – JAMA

Patient Page: Screening for Lipid Disorders in Children and Adolescents – JAMA

Commentary: USPSTF: Screening Kids for Lipid Disorders Still Needs More Data – TCTMD

 


M-A | Hepatic, extra-hepatic outcomes and causes of mortality in NAFLD

20 Jul, 2023 | 10:59h | UTC

Hepatic, Extra-hepatic Outcomes and Causes of Mortality in NAFLD – An Umbrella Overview of Systematic Review of Meta-Analysis – Journal of Clinical and Experimental Hepatology

 


Review | Painful diabetic peripheral neuropathy

20 Jul, 2023 | 10:53h | UTC

Painful Diabetic Peripheral Neuropathy: Practical Guidance and Challenges for Clinical Management – Diabetes, Metabolic Syndrome and Obesity

 


IARC, WHO agency, identifies aspartame as potentially carcinogenic but probably safe within established acceptable daily intake

18 Jul, 2023 | 13:58h | UTC

News Release: Aspartame hazard and risk assessment results released – World Health Organization

Commentaries:

Expert reaction to IARC and JEFCA summary on aspartame – Science Media Centre

Does artificial sweetener aspartame really cause cancer? What the WHO listing means for your diet soft drink habit – The Conversation

Aspartame Hazard and Risk Assessment Results Released by IARC and JECFA – The ASCO Post

 


Review | Cushing Syndrome

13 Jul, 2023 | 13:08h | UTC

Cushing Syndrome: A Review – JAMA (free for a limited period)

Audio clinical review: Diagnosis and Treatment of Cushing Syndrome – JAMA

 


RCT | Metformin boosts effectiveness of lifestyle interventions for diabetes prevention in individuals with impaired glucose regulation

13 Jul, 2023 | 13:07h | UTC

Safety and effectiveness of metformin plus lifestyle intervention compared with lifestyle intervention alone in preventing progression to diabetes in a Chinese population with impaired glucose regulation: a multicentre, open-label, randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Related Study: Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin – New England Journal of Medicine (link to abstract – $ for full-text)

 


Single Arm Trial | Low-carbohydrate diet improves glycemic control in type 1 diabetes

13 Jul, 2023 | 13:04h | UTC

Effects of a low-carbohydrate diet in adults with type 1 diabetes management: A single arm non-randomised clinical trial – PLOS One

Related:

Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet – Pediatrics (link to abstract – $ for full-text)

Meta-analysis of randomized trials: patients adhering to a low carbohydrate diet for six months may experience remission of diabetes without adverse consequences

RCT | A calorie-unrestricted low-carbohydrate, high-fat diet resulted in short-term weight loss and better glycemic control.

Comparison of the Effectiveness of Low Carbohydrate Versus Low Fat Diets, in Type 2 Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials – Nutrients

Consensus Statement: Effect of carbohydrate-restricted diets and intermittent fasting on obesity, type 2 diabetes mellitus, and hypertension management.

Effects of a 6-month, low-carbohydrate diet on glycaemic control, body composition, and cardiovascular risk factors in patients with type 2 diabetes: An open-label randomized controlled trial – Diabetes, Obesity and Metabolism

Lower carbohydrate diets for adults with type 2 diabetes – British Journal of Nutrition

Low carbohydrate diet: Insights from a general practice service in patients with type 2 diabetes

Diabetes Canada Position Statement on Low-Carbohydrate Diets for Adults With Diabetes: A Rapid Review – Canadian Journal of Diabetes

Low Carbohydrate Diets for Diabetes: A Review of the Clinical Effectiveness and Guidelines – Canadian Agency for Drugs and Technologies in Health

Adapting diabetes medication for low carbohydrate management of type 2 diabetes: a practical guide – British Journal of General Practice

 


2023 ETA clinical practice guidelines for thyroid nodule management

12 Jul, 2023 | 13:48h | UTC

2023 European Thyroid Association clinical practice guidelines for thyroid nodule management – European Thyroid Journal

 


The 2023 Bethesda System for reporting thyroid cytopathology

12 Jul, 2023 | 13:46h | UTC

The 2023 Bethesda System for Reporting Thyroid Cytopathology – Thyroid

 


Cohort Study | Long-term use of menopausal hormone therapy linked to heightened dementia risk

11 Jul, 2023 | 14:04h | UTC

Menopausal hormone therapy and dementia: nationwide, nested case-control study – The BMJ

Editorial: Menopausal hormone therapy and dementia – The BMJ

News Release: Menopausal hormone therapy linked to increased rate of dementia – BMJ Newsroom

Commentaries: Expert reaction to observational study on HRT and dementia – Science Media Centre

 


RCT | No significant difference in weight loss between intermittent fasting and calorie restriction

10 Jul, 2023 | 13:56h | UTC

Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Intermittent fasting and traditional calorie counting shown to be about equal for weight loss – American College of Physicians

Commentary: Intermittent fasting and calorie counting about equal for weight loss – new study – The Conversation

Related:

RCT | Intermittent fasting plus early time-restricted eating vs. calorie restriction and standard care in adults at risk of type 2 DM

RCT | Time-restricted eating not more effective than daily calorie restriction for managing nonalcoholic fatty liver disease

Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis – Frontiers in Nutrition

Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial – Cell Metabolism

Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults With Obesity: A Randomized Clinical Trial – JAMA Internal Medicine

Effects of Intermittent Fasting in Human Compared to a Non-intervention Diet and Caloric Restriction: A Meta-Analysis of Randomized Controlled Trials – Frontiers in Nutrition

Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition

Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine

Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open

 


Cohort Study | A diet high in fruits, vegetables, nuts, legumes, fish, and dairy linked with decreased mortality and CVD globally

10 Jul, 2023 | 13:39h | UTC

Diet, cardiovascular disease, and mortality in 80 countries – European Heart Journal

Editorial: Identifying nutritional priorities for global health: time for a more PURE focus on protective foods – European Heart Journal

News Release: Global diet study challenges advice to limit high-fat dairy foods – European Society of Cardiology

 

Commentary on Twitter

 


RCT | Weekly Tirzepatide outperforms placebo in weight management for type 2 diabetes patients

7 Jul, 2023 | 16:24h | UTC

Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Tirzepatide triumphs in significant weight reduction for people with type 2 diabetes – News Medical

 


Review | Cardiovascular outcomes in patients with diabetes and kidney disease

7 Jul, 2023 | 16:13h | UTC

Cardiovascular Outcomes in Patients With Diabetes and Kidney Disease: JACC Review Topic of the Week – Journal of the American College of Cardiology

 


Review | Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome

7 Jul, 2023 | 16:08h | UTC

Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome – The BMJ

 


Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.