Endocrinology

Global Atlas on Childhood Obesity

7 Oct, 2019 | 06:01h | UTC

Review: MRI of Adrenal Gland

4 Oct, 2019 | 07:20h | UTC

Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)

Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)

 

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Commentaries: Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction – DAPA-HF – American College of Cardiology (free) Dapagliflozin reduces death and hospitalisation in patients with heart failure – European Society of Cardiology (free)

 

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Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: High-Dose Vitamin D Might Reduce Bone Mineral Density – NEJM Journal Watch (free)

 

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Podcast: Diabetes Update

27 Aug, 2019 | 01:54h | UTC

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ (free)

Related: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)

Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.

 

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Long-term adverse events after sleeve gastrectomy or gastric bypass: a 7-year nationwide, observational, population-based, cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentary: Death Risk Drops After Bariatric Surgery in Obese Patients – MedPage Today (free registration required)

Related Research: Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)

 

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Medications Affecting the Biochemical Conversion to Type 2 Diabetes: A Systematic Review and Meta-Analysis – The Journal of Clinical Endocrinology & Metabolism (free)

α-Glucosidase inhibitors, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, metformin, orlistat, phentermine/topiramate, and pioglitazone significantly reduced the risk of biochemical conversion to T2DM, whereas statins and nateglinide increased the risk”

 


Diagnosing the Onset of Menopause

23 Jul, 2019 | 01:47h | UTC

Diagnosing the Onset of Menopause – JAMA (free for a limited period)

Clinical Review Audio: Diagnosing Menopause (free)

 


Clinical Use of Bone Turnover Markers

14 Jul, 2019 | 19:15h | UTC

Clinical Use of Bone Turnover Markers – JAMA (free for a limited period)

 


Review: Subclinical Hypothyroidism

10 Jul, 2019 | 02:36h | UTC

Subclinical Hypothyroidism – A Review – JAMA (free link for a limited period)

Related: BMJ Guideline: Treatment of Subclinical Hypothyroidism (free guideline and commentaries)

 


Vitamin D Supplementation and Cardiovascular Disease Risks in More Than 83 000 Individuals in 21 Randomized Clinical Trials: A Meta-analysis – JAMA Cardiology (free for a limited period)

Commentaries: The Demise of Vitamin D for Cardiovascular Prevention – JAMA Cardiology (free for a limited period) AND Does Vitamin D Supplementation Provide Cardiovascular Protection? – MPR (free)

 

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Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Dulaglutide Cuts Cardiovascular Risk in Type 2 Diabetes – NEJM Journal Watch (free)

During a median follow-up of 5.4 years, the primary outcome (a composite endpoint of non-fatal myocardial infarction, non-fatal stroke, or death from cardiovascular causes) occurred in 12.0% of participants in the dulaglutide group and in 13.4% of participants in the placebo group (incidence rate of 2.4 per 100 person-years vs 2.7 per 100 person-years in the placebo group).

 


Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: review of acute decompensated diabetes in adult patients – The BMJ (free for a limited period)

 

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Review: Menopausal Hormone Therapy

31 May, 2019 | 06:30h | UTC

Menopausal Hormone Therapy – JAMA (free for a limited period)

Podcast: Menopausal Hormone Therapy (free audio)

 


Review: Diabetes and Bone

23 May, 2019 | 13:13h | UTC