Open access

NEWS - Dermatology

Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: High-tech treatment of open leg wounds no better than using regular dressings – University of Warwick (free) AND Negative-Pressure Therapy No Better for Open Fractures – Medscape (free registration required)

“Negative pressure wound therapy did not improve 12-month disability for patients with severe open fracture of the lower limb compared with standard wound dressing”


Low dose aspirin as adjuvant treatment for venous leg ulceration: pragmatic, randomised, double blind, placebo controlled trial (Aspirin4VLU) – The BMJ (free)

“Low dose aspirin does not increase time to healing of venous leg ulcers, percentage healed, estimated change in venous leg ulcer area, or change in health related quality of life”.


Molluscum contagiosum is best left to clear by itself – NIHR Signal (free)

Original article: Interventions for cutaneous molluscum contagiosum – Cochrane Library (link to abstract – $ for full-text)

“Clinicians should advise people with a healthy immune system to leave molluscum contagiosum to clear by itself” (RT @NIHR_DC  see Tweet)


Perspectives: Augmenting diagnostic vision with AI – The Lancet (free registration required)


Cochrane What is the best medication for a fungal infection of the toenail? – Cochrane Library (free)

Full review: Oral antifungal medication for toenail onychomycosis – Cochrane Library (link to abstract – $ for full-text)

Terbinafine probably leads to better cure rates than azoles, with the same risk of adverse events. Griseofulvin is no better and has more adverse effects than azoles.


The Solution for Skin Ailments Could Be Right Under Your Nose – The New York Times (10 articles per month are free)

Original article: Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatites – Science Translational Medicine (link to abstract – $ for full-text)

“Modifying the skin’s own bacteria may lead to treatments for acne, eczema and other common ailments” (RT @NYTHealth see Tweet)


Topical antimicrobial agents for treating foot ulcers in people with diabetes – Cochrane Library (link to summary – & for full-text)

“Topical antimicrobial dressing may increase foot ulcer healing in people with diabetes” (RT @CochraneUK see Tweet)


Going Under the Knife, With Eyes and Ears Wide Open – New York Times (free access to 10 articles per month)

“More and more surgeries are being performed with the patient awake and looking on, for financial and medical reasons”.


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