Targeted temperature management in the ICU

23Jun
2017

Time-to-Furosemide Treatment and Mortality in Acute Heart Failure

23Jun
2017

Time-to-Furosemide Treatment and Mortality in Patients Hospitalized With Acute Heart Failure – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: Door-to-Furosemide Time in Acute Heart Failure – American College of Cardiology, Latest in Cardiology (free)

“God help us if this sort of observational data leads to “door to furosemide time” being adopted as a quality measure” (RT @adamcifu see Tweet)

 

Guideline summary: Consensus on Surgical Treatment of Infective Endocarditis

23Jun
2017

Head Positioning in Acute Stroke

23Jun
2017

Continuous positive airway pressure for children with undifferentiated respiratory distress

23Jun
2017

Cardiopulmonary resuscitation – 30:2 or just keep going?

22Jun
2017

Cardiopulmonary resuscitation – 30:2 or just keep going? – by Scott Munro, in Evidently Cochrane (free) (RT @NIHR_DC see Tweet)

“Untrained bystander CPR had better outcomes when given telephone advice from EMS services to perform continuous CPR, rather than interrupted CPR with rescue breaths”. For trained EMS professionals, “it is possible that there is little or no difference between the two approaches”.

 

Performance Improvement: Phenytoin Toxicity

22Jun
2017

Performance Improvement: Phenytoin Toxicity – JAMA (free)

Interesting case of medication error and prevention of subsequent adverse events (RT @JAMA_current see Tweet)

 

Acupuncture for analgesia in the emergency department

21Jun
2017

Nucleated RBCs may be a predictor of post-discharge mortality and unplanned hospital readmission

21Jun
2017

Nucleated red blood cells, critical illness survivors and postdischarge outcomes: a cohort study – Critical Care (free)

“Presence of nucleated RBCs is a robust predictor of post-discharge mortality and unplanned hospital readmission” (RT @Crit_Care see Tweet)

 

Corticosteroids not helpful for acute urticaria

21Jun
2017

Antiplatelet Therapy in Patients With Coronary Stents Undergoing Elective Noncardiac Surgery

20Jun
2017

Antibiotic stewardship reduces the incidence of antibiotic-resistant bacteria

20Jun
2017

Inspired by War Zones, Balloon Device May Save Civilians From Fatal Blood Loss

20Jun
2017

Management of Potential Organ Donor

16Jun
2017

Association of Adverse Events With Antibiotic Use in Hospitalized Patients

14Jun
2017

Association of Adverse Events With Antibiotic Use in Hospitalized Patients – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Antibiotic-Associated Adverse Events Common – Medscape (free registration required)

“20% of hospitalized patients receiving antibiotics had adverse drug event. Of those, 20% of regimens inappropriate” (RT @PeterPronovost see Tweet)

 

A Test in Context: Fractional Flow Reserve: Accuracy, Prognostic Implications, and Limitations

14Jun
2017

Combination inhaler treatment in emergency departments may reduce admissions for asthma attacks

14Jun
2017

Improving Recognition of Pediatric Severe Sepsis

13Jun
2017

Prevention of acute kidney injury and protection of renal function in the intensive care unit

12Jun
2017

Head injury: assessment and early management

9Jun
2017

Practice Guidelines for Preoperative Fasting

9Jun
2017

Handshake-free zones to prevent infections?

8Jun
2017

Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (again)

7Jun
2017

Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis: Systematic Review and Meta-analysis of Controlled Trials – Annals of Surgery (link to abstract – $ for full-text)

Commentary: Antibiotics Versus Surgery: Equally Effective in Treating Appendicitis? – Medscape (free registration required)

This meta-analysis and the author’s conclusions do not favor antibiotics alone for the treatment of uncomplicated appendicitis, contradiction the results of other recent meta-analysis, as well as a recent guideline on the subject, suggesting antibiotics might be an option in selected cases.

 

Simplified diagnostic management of suspected pulmonary embolism

7Jun
2017

What is the best antidote for a jellyfish sting?

7Jun
2017

Predicting the Need for Fluid Therapy

6Jun
2017

Reengineering the analgesic ladder for critically ill patients

6Jun
2017

Heparin-induced thrombocytopenia

4Jun
2017

Prophylactic Acid-Suppressive Therapy in Hospitalized Adults

2Jun
2017

Management of Adult Patients With Acute Carbon Monoxide Poisoning

31May
2017

Antibiotic therapy for nearly one in four adults with pneumonia does not work

29May
2017

Guidelines on the Management of Intra-Abdominal Infection

26May
2017

Thrombolysis may reduce complications of deep vein thrombosis

26May
2017

Thrombolysis may reduce complications of deep vein thrombosis – NIHR Signal (free)

Original article: Thrombolysis for acute deep vein thrombosis – Cochrane Library (Link to abstract – $ for full-text)

Thrombolysis reduced post-thrombotic syndrome, but lead to more bleeding complications than standard anticoagulation. “Individuals with clots in the pelvis and thigh, which carry higher risk of complications, may be likely to gain most benefit”.

 

Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation

25May
2017

Very strict blood sugar control in critically ill children provides no benefit

25May
2017

Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease

25May
2017

Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text) (RT @Gas_Craic see Tweet)

“Compared with culprit-only intervention, the complete revascularisation strategy may be superior due to lower proportions of long-term cardiovascular mortality, long-term revascularisation, and long-term non-fatal myocardial infarction, but these findings are based on evidence of very low quality”

 

Angioedema in the emergency department

25May
2017

Perioperative management of patients on direct oral anticoagulants

24May
2017

Cardiopulmonary Resuscitation in Adults and Children With Mechanical Circulatory Support

24May
2017

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

19May
2017

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis – New England Journal of Medicine (free)

Commentary: Doctors have resisted guidelines to treat sepsis. New study suggests those guidelines save lives – STAT News (free)

“For every hour you delay antibiotics in sepsis, mortality goes up” (RT @CMichaelGibson see Tweet)

“Trauma: Golden Hour

Cardiology: Time is muscle

Neurology: Time is brain

Sepsis: Early antibiotics to survive”

(interesting remark by @CMichaelGibson see Tweet)

 

Nutrition and metabolism in burn patients

18May
2017

Renal dysfunction in cirrhosis

17May
2017

BTS guideline for oxygen use in adults in healthcare and emergency settings

16May
2017

Management of intra-abdominal infections

15May
2017

Reducing brain injury following cardiopulmonary resuscitation

11May
2017

Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes

9May
2017

Intravenous fluid therapy in adults in hospital – NICE Guideline

9May
2017

Series: Acute Kidney Injury in the Intensive Care Unit

6May
2017

Management of severe perioperative bleeding

6May
2017

Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017

5May
2017

Selection of patients for intra-arterial treatment for acute ischaemic stroke

4May
2017

Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials – The BMJ (free)

New decision tool: MR CLEAN-R Registry (free)

This new clinical decision tool will improve the selection of patients with acute ischemic stroke who will benefit the most from intra-arterial treatment.

 

Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest

4May
2017

Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (Link to abstract – $ for full-text)

Quick Take Video Summary: Bystander Efforts in Out-of-Hospital Cardiac Arrest (free)

Commentary: Bystander CPR and Defibrillation Are Associated with Better Long-Term Outcomes – Journal Watch (free)

In patients who have initially survived after out-of-hospital cardiac arrest, those who were submitted to bystander CPR and defibrillation had lower risk of brain damage, nursing home admission and death after one year when compared to patients who survived but were not submitted to bystander CPR.

 

Effect of Using the HEART Score in Patients With Chest Pain in the Emergency Department

2May
2017

Echocardiography and lung ultrasonography for the assessment and management of acute heart failure

2May
2017

Review: Acute Respiratory Distress Syndrome

2May
2017

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage

27Apr
2017

Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure

27Apr
2017

Head injury decision rules in children

26Apr
2017

Accuracy of PECARN, CATCH, and CHALICE head injury decision rules in children: a prospective cohort study – The Lancet (link to abstract – $ for full-text)

Sources: External Validation of Three Decision Rules for Pediatric Head Injury – Journal Watch (free) AND Best way to diagnose head injuries in children and minimize CT scans – ScienceDaily (free) AND PECARN, CATCH, CHALICE … or None of the Above? – By Ryan P. Radecki, MD, in Emergency Medicine Literature of Note (free)

The 3 decision rules performed well with negative predictive values >99%. The PECARN clinical decision rule was more sensitive and missed only 1 patient with clinically important traumatic brain injury, but was less specific, meaning more CTs would be required. These findings indicate that CT can generally be avoided if one of the prediction rules are negative.

 

Aneurysmal Subarachnoid Hemorrhage: Diagnosis and Treatment

25Apr
2017

The efficacy of bedside chest ultrasound

24Apr
2017

Single Cardiac Troponin Test Plus ECG Can Quickly Rule Out MI

19Apr
2017

Rapid Rule-out of Acute Myocardial Infarction with a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

See also: High-Sensitivity Troponin T Test Rules Out AMI in ED – Medscape (free registration required) AND Meta-Analysis: Single Cardiac Troponin Test Plus ECG Can Quickly Rule Out MI – Physician’s First Watch (free)

“This analysis indicates that a nonischemic ECG and a single negative High-Sensitivity Cardiac Troponin T only misses about 1 in 100 myocardial infarctions – and can provide rapid, useful information in an assessment.” (from Physician’s First Watch commentary above).

 

New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management

18Apr
2017

The hospital of tomorrow in 10 points

12Apr
2017

Emergencies in Hematology and Oncology

11Apr
2017

Emergencies in Hematology and Oncology – Mayo Clinic Proceedings (free)

Comprehensive review covering the most common oncological emergencies.

 

Benefits of Endovascular Treatment for Stroke Last at Least 2 Years

7Apr
2017

Australian Clinical Guidelines for the Management of Acute Coronary Syndromes

6Apr
2017

The wound/burn guidelines – Japanese Dermatological Association

5Apr
2017

American College of Radiology (ACR) Appropriateness Criteria Adds Topics

4Apr
2017

ACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)

Browse Appropriateness Criteria Topics (free)

Source: Newswise

This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.

 

Management of Inpatient Hyperglycemia and Diabetes in Older Adults

4Apr
2017

Anemia and blood transfusion in the critically ill patient with cardiovascular disease

3Apr
2017

Corticosteroids in septic shock

3Apr
2017

Gastric Acid Suppression and Clostridium difficile Infection

28Mar
2017

Association of Gastric Acid Suppression with Recurrent Clostridium difficile Infection: A Systematic Review and Meta-analysis (link to abstract – $ required for full-text)

“Another study that suggests gastric acid suppression may increase risk of recurrent Clostridium difficile” (RT @PreetiNMalani)

 

Enhanced recovery after surgery

28Mar
2017

ESPEN guideline: Clinical nutrition in surgery

27Mar
2017

Annual Update in Intensive Care and Emergency Medicine 2017

23Mar
2017

Selected articles from the Annual Update in Intensive Care and Emergency Medicine 2017 – Critical Care (free)

10 open access review articles selected from the Annual Update in Intensive Care and Emergency Medicine 2017.

 

Mechanical ventilation in obese ICU patients

23Mar
2017
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