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Chest Medicine (all articles)

RCT: A 2-week interruption in methotrexate treatment doubles the antibody response to a COVID-19 booster vaccine.

29 Jun, 2022 | 12:10h | UTC

Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial – The Lancet Respiratory Medicine

News Releases:

Interrupting the treatment of vulnerable people on immune-suppressing medicines, doubles their antibody response to COVID-19 booster vaccination – University of Nottingham

Interrupting immune-suppressing treatment can boost COVID vaccine response – Imperial College London

Commentaries:

Improving COVID-19 vaccine immunogenicity by interrupting methotrexate treatment – The Lancet Respiratory Medicine

Covid-19: Pausing immune suppressing drugs enhances antibody response to boosters, study shows – The BMJ

Related Study: Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine: a randomised clinical trial – Annals of Rheumatic Diseases

 

Commentary on Twitter

 


Perspective | Fast-evolving COVID variants complicate vaccine updates.

29 Jun, 2022 | 12:01h | UTC

Fast-evolving COVID variants complicate vaccine updates – Nature

 


Retrospective Cohort Study: Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation.

29 Jun, 2022 | 11:54h | UTC

Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation – Critical Care

 


An analysis of SARS-CoV-2 vaccine reactogenicity: variation by type, dose, and history, severity, and recency of prior SARS-CoV-2 infection.

29 Jun, 2022 | 11:52h | UTC

An Analysis of SARS-CoV-2 Vaccine Reactogenicity: Variation by Type, Dose, and History, Severity, and Recency of Prior SARS-CoV-2 Infection – Open Forum Infectious Diseases

 


Systematic Review: Exercise versus airway clearance techniques for people with cystic fibrosis.

29 Jun, 2022 | 11:10h | UTC

Exercise versus airway clearance techniques for people with cystic fibrosis – Cochrane Library

Summary: Exercise versus airway clearance for people with cystic fibrosis – Cochrane Library

 


Brief Review: Noninvasive respiratory support in intensive care medicine.

29 Jun, 2022 | 11:06h | UTC

Noninvasive respiratory support in intensive care medicine – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Systematic Review: Trastuzumab Deruxtecan-induced interstitial lung disease/pneumonitis in ERBB2-positive advanced solid malignancies.

29 Jun, 2022 | 10:59h | UTC

Trastuzumab Deruxtecan-Induced Interstitial Lung Disease/Pneumonitis in ERBB2-Positive Advanced Solid Malignancies: A Systematic Review – Drugs

 


Guideline: Sleep-related breathing disorders in adults.

28 Jun, 2022 | 11:21h | UTC

Partial update of the German S3 Guideline Sleep-Related Breathing Disorders in Adults – Somnologie

 


RCT: Two-day vs. seven-day course of levofloxacin in acute COPD exacerbation.

28 Jun, 2022 | 11:19h | UTC

Two-day versus seven-day course of levofloxacin in acute COPD exacerbation: a randomized controlled trial – Therapeutic Advances in Respiratory Disease

Commentary: Antibiotics in COPD Exacerbations – 2 days vs 7 days – RebelEM

 


Review: Primary graft dysfunction after clinical lung transplantation.

28 Jun, 2022 | 10:37h | UTC

A Focused Review on Primary Graft Dysfunction after Clinical Lung Transplantation: A Multilevel Syndrome – Cells

 


[Press Release – not published yet]: RCT: Sanofi-GSK report its vaccine targeted against ancestral and Beta strains had an overall efficacy of 72% against the Omicron variant.

27 Jun, 2022 | 11:52h | UTC

Press Release: Sanofi-GSK first to report a successful efficacy study against Omicron with COVID-19 Beta-containing vaccine – Sanofi

Commentaries: Bivalent COVID Vax Gets Phase III Win Against Omicron, Companies Say — Sanofi, GSK boast of 72% efficacy against Omicron variant – MedPage Today (free registration required)

 


Perspective | What Omicron’s BA.4 and BA.5 variants mean for the pandemic.

27 Jun, 2022 | 11:48h | UTC

What Omicron’s BA.4 and BA.5 variants mean for the pandemic – Nature

 


M-A: The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults.

27 Jun, 2022 | 11:42h | UTC

The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults: a systematic review and meta-analysis – Age and Ageing

 


Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study.

27 Jun, 2022 | 11:29h | UTC

Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study – The Lancet Digital Health

 

Commentary on Twitter

 


Phase 2a RCT: Vaccine efficacy in adults in a respiratory syncytial virus challenge study.

27 Jun, 2022 | 11:21h | UTC

Vaccine Efficacy in Adults in a Respiratory Syncytial Virus Challenge Study -New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Challenge Study Shows Efficacy of RSV Vaccine in Healthy Adults – HealthDay

 

Commentary on Twitter

 


Systematic Review: Short‐acting inhaled bronchodilators for cystic fibrosis.

27 Jun, 2022 | 11:15h | UTC

Short‐acting inhaled bronchodilators for cystic fibrosis – Cochrane Library

Summary: Short-acting inhaled bronchodilators for cystic fibrosis – Cochrane Library

 


Cohort Study: COVID-19 trajectories among 57 million adults in England.

24 Jun, 2022 | 11:34h | UTC

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records – The Lancet Digital Health

News Release: Most comprehensive analysis of COVID-19 data reveals previously unattributed deaths – Health Data Research UK

 

Commentary from one of the authors on Twitter (thread – click for more)

 


Position Paper: Teleconsultation in respiratory medicine.

24 Jun, 2022 | 11:11h | UTC

Teleconsultation in respiratory medicine – A position paper of the Portuguese Pulmonology Society – Pulmonology

 


Review: The physiological basis of pulmonary arterial hypertension.

24 Jun, 2022 | 10:45h | UTC

The physiological basis of pulmonary arterial hypertension – European Respiratory Journal

 


Study Commentary | How FAST can you spot a pneumothorax? breaking down a surprising result comparing ultrasound and chest radiograph in traumatic pneumothorax.

24 Jun, 2022 | 10:39h | UTC

How FAST Can You Spot a Pneumothorax? Breaking Down a Surprising Result Comparing Ultrasound and Chest Radiograph in Traumatic Pneumothorax – Annals of Emergency Medicine

Original Study: Not so FAST—Chest ultrasound underdiagnoses traumatic pneumothorax – Journal of Trauma and Acute Care Surgery (link to abstract – $ for full-text)

 


AHA Scientific Statement: Cardiopulmonary consequences of vaping in adolescents.

23 Jun, 2022 | 13:03h | UTC

Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association – Circulation Research

News Release: Action needed to reduce e-cigarette use among adolescents to lower lifetime CVD risk – American Heart Association

 


Ivermectin for COVID-19 Cochrane review update: 11 trials and no evidence of benefit shown.

23 Jun, 2022 | 10:38h | UTC

News Release: Ivermectin for COVID-19 review update: 11 trials and no evidence of benefit shown – Liverpool School of Tropical Medicine

Original Article: Ivermectin for preventing and treating COVID‐19 – Cochrane Library

Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library

 


Systematic Review: SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19.

23 Jun, 2022 | 10:37h | UTC

SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19 – Cochrane Library

Summary: Are laboratory-made COVID-19-specific monoclonal antibodies effective to prevent COVID-19 in adults? – Cochrane Library

 


ASA and APSF statement on perioperative testing for the COVID-19 virus.

22 Jun, 2022 | 12:19h | UTC

ASA and APSF Statement on Perioperative Testing for the COVID-19 Virus – American Society of Anesthesiologists

Commentary: ASA, APST Update Perioperative SARS-CoV-2 Testing Recommendations – HealthDay

Related:

Surgical Triage and Timing for Patients with COVID: A Guidance Statement from the Society of Thoracic Surgeons – Annals of Thoracic Surgery

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 


Review: Sex differences in sequelae from COVID-19 infection and in long COVID syndrome.

22 Jun, 2022 | 12:06h | UTC

Sex differences in sequelae from COVID-19 infection and in long COVID syndrome: a review – Current Medical Research and Opinion

Commentary: Women more likely to have long COVID, different symptom profile – CIDRAP

 


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