Chest Medicine (all articles)
Consensus Paper | Lung ultrasound in acute and chronic heart failure
24 Jul, 2023 | 13:06h | UTC
RCT | Long-term Doxycycline for COPD does not reduce exacerbations, except possibly in severe cases or with low eosinophils
24 Jul, 2023 | 12:50h | UTCA Double-Blind, Randomised, Placebo-controlled Trial of Long-Term Doxycycline Therapy on Exacerbation Rate in Patients with Stable COPD – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
M-A | Exposure to smoke, overcrowding, poor living conditions, and contact with TB cases identified as risk conditions for pediatric TB
24 Jul, 2023 | 12:43h | UTC
Correspondence | Potential “healthy vaccinee bias” in a study of BNT162b2 vaccine against Covid-19
21 Jul, 2023 | 13:43h | UTC
Commentary from the author on Twitter (thread – click for more)
Our correspondence is out in @njem written w @VPrasadMDMPH & Ram Duriseti
We show v strong evidence of healthy vaccinee bias in an Israeli study of Pfizer booster vs covid death, which wasn't disclosed
Could explain ALL reported benefit of the booster?https://t.co/F3WeafvUnw pic.twitter.com/b29YQ0lblh
— Tracy Høeg, MD, PhD (@TracyBethHoeg) July 20, 2023
Review | Management of severe acute respiratory distress syndrome
20 Jul, 2023 | 11:10h | UTCManagement of severe acute respiratory distress syndrome: a primer – Critical Care
Related: ESICM guidelines on ARDS: definition, phenotyping and respiratory support strategies
M-A | Population-level smoke-free legislation tied to better cardiovascular, respiratory, birth outcomes
19 Jul, 2023 | 14:13h | UTCCommentary: Smoke-Free Legislation Linked to Drop in Adverse Health Outcomes – HealthDay
AHA Scientific Statement | Cardiopulmonary impact of electronic cigarettes and vaping products
18 Jul, 2023 | 13:56h | UTCNews Releases:
Top Things to Know: Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products – American Heart Association
Commentary: Vaping’s Risks to CV Health Not Yet Fully Known: AHA – CIDRAP
Cohort study | High-risk patent foramen ovale associated with increased decompression illness in scuba divers
18 Jul, 2023 | 13:43h | UTCDecompression Illness in Divers With or Without Patent Foramen Ovale: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: SCUBA divers with PFO at higher risk for decompression illness than previously thought – American College of Physicians
Commentary on Twitter
A study of #ScubaDivers found presence of high-risk PFO was associated with increased risk of decompression illness. Authors recommend divers with PFO should consider not diving or adhering to more conservative protocol: https://t.co/5Glt9B8Xup pic.twitter.com/AYbrDxiL0p
— Annals of Int Med (@AnnalsofIM) July 11, 2023
Review | CT and chest radiography in evaluation of mechanical circulatory support devices for acute heart failure
18 Jul, 2023 | 13:28h | UTC
Consensus Statement | Aerosol therapy in adult critically ill patients
14 Jul, 2023 | 13:01h | UTC
M-A | Drug therapies for treatment of idiopathic pulmonary fibrosis
14 Jul, 2023 | 12:40h | UTC
M-A | Adjunctive corticosteroids improve survival, clinical outcomes in severe community-acquired pneumonia
13 Jul, 2023 | 13:09h | UTCRelated:
Corticosteroids in Community-Acquired Bacterial Pneumonia: a Systematic Review, Pairwise and Dose-Response Meta-Analysis – Journal of General Internal Medicine (if the link is paywalled, try this one)
RCT | Hydrocortisone reduces mortality in severe community-acquired pneumonia
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
RCT | Cytisinicline shows significant efficacy in smoking cessation over placebo
13 Jul, 2023 | 12:58h | UTCCytisinicline for Smoking Cessation: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
See also: Visual Abstract
AHA Scientific Statement | Pulmonary hypertension in congenital heart disease
11 Jul, 2023 | 13:57h | UTC
M-A | Catheter-directed thrombolysis vs. systemic thrombolysis and anticoagulation in intermediate- or high-risk pulmonary embolism
11 Jul, 2023 | 13:47h | UTC
M-A | Efficacy of varenicline versus bupropion for smoking cessation
10 Jul, 2023 | 13:23h | UTC
Review | Post-COVID Conditions
7 Jul, 2023 | 16:21h | UTCPost-COVID Conditions – Mayo Clinic Proceedings
Review | Hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA): two sides of the same coin
7 Jul, 2023 | 16:01h | UTCHES and EGPA: Two Sides of the Same Coin – Mayo Clinic Proceedings
SR | Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
5 Jul, 2023 | 01:04h | UTC
Review | Respiratory challenges and ventilatory management in different types of acute brain-injured patients
3 Jul, 2023 | 14:17h | UTC
Update on transfusion-related acute lung injury: an overview of its pathogenesis and management
30 Jun, 2023 | 14:31h | UTC
Review | Breathing difficulties after covid-19: a guide for primary care
29 Jun, 2023 | 14:04h | UTCBreathing difficulties after covid-19: a guide for primary care – The BMJ
The exposome in respiratory diseases: multiple preventable risk factors from early life to adulthood
27 Jun, 2023 | 13:32h | UTC
Commentary on Twitter
The increasing global burden of respiratory diseases over recent decades raises questions about the lifelong impact of environmental factors during industrialisation and urbanisation. There is a clear need for action in primary and secondary prevention. https://t.co/MFzkETBr2X pic.twitter.com/jp9LYSiSAR
— ERS publications (@ERSpublications) June 20, 2023
M-A | Risk factors for non-tuberculous mycobacterial pulmonary disease
27 Jun, 2023 | 13:27h | UTCCommentary: Comorbid respiratory disease key predictor of NTM-PD – MDedge
Cohort Study | Association of preterm birth with increased asthma and COPD risk in adulthood
26 Jun, 2023 | 00:45h | UTCSummary: This population-based register study investigated the correlation between gestational ages (GA) and obstructive airway diseases like asthma and chronic obstructive pulmonary disease (COPD) in adulthood. The study used registry data from 706,717 individuals born between 1987-1998 in Finland (4.8% preterm), and 1,669,528 individuals born from 1967-1999 in Norway (5.0% preterm). The study observed care episodes of asthma and COPD using nationwide healthcare registers.
The results showed an increased risk of obstructive airway disease in adulthood for those born at <28 or 28–31 completed weeks of gestation. Even after adjustments, the risk remained 2-3 times greater compared to those who were born full term (at 39-41 completed weeks). Additionally, the risk for COPD at age 30–50 was significantly higher for those born at <28 weeks, with an odds ratio (OR) of 7.44. The study also identified that bronchopulmonary dysplasia (BPD) in infancy increased the odds of obstructive airway disease for those born at <28 and 28–31 weeks.
These findings suggest that preterm birth is a notable risk factor for asthma and COPD in adulthood, and this risk was observed across all gestational ages before full term. The study recommends diagnostic vigilance for adults born very preterm presenting with respiratory symptoms. However, the researchers also noted the potential limitations of using registry data, which might include residual confounding from unmeasured confounders and lack of data on certain prenatal or early life factors.
Article: Preterm birth and asthma and COPD in adulthood: a nationwide register study from two Nordic countries – European Respiratory Journal (free for a limited period)
Commentary on Twitter
In this population-based study of 2.4 million people from Finland and Norway, adults born preterm were at higher risk for asthma and COPD at ages 18–50 years. The risks were observed across all gestational ages before full term in a dose-response manner. https://t.co/bGsAOrwAxV pic.twitter.com/WmCoc6cPu2
— ERS publications (@ERSpublications) June 22, 2023