Chest Medicine

Trends and risk factors of mortality and disability adjusted life years for chronic respiratory diseases from 1990 to 2017: systematic analysis for the Global Burden of Disease Study 2017 – The BMJ (free)

Commentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)


Related Commentary on Twitter


Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia – JAMA Internal Medicine (free for a limited period)

Editorial: Overuse of Broad-Spectrum Antibiotics for Pneumonia (free for a limited period)


Related Commentary on Twitter


Management of Acute Asthma in Adults in 2020 – JAMA (free for a limited period)

Related Article: Outpatient Management of Chronic Asthma in 2020 – JAMA (free for a limited period)

Editorial: New Therapeutic Strategies for Asthma – JAMA (free for a limited period)


Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Related: Meta-Analysis: Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients with Moderate to Severe Acute Respiratory Distress Syndrome (free resources on the subject)


Related Commentary on Twitter


Conservative versus Interventional Treatment for Spontaneous Pneumothorax – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: ‘Hands Off approach’ best to treat a collapsed lung – study – Voxy (free) AND Don’t Just Do Something, Stand There (Watching Spontaneous Pneumothoraces) – NEJM Journal Watch (free)


Related Commentary on Twitter


Severe Flu Management: A Point of View

23 Jan, 2020 | 09:42h | UTC

E-cigarettes: how risky are they? – World Health Organization (free)


Related Commentary on Twitter (Thread – Click for More)


Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: post-hoc safety analysis of two randomised controlled trials – The Lancet Infectious Diseases (free registration required)

Commentaries: What is the best regimen to treat latent tuberculosis infection? – The Lancet Infectious Diseases (free) AND Four Months of Rifampicin May Be Best Option for Latent TB – Medscape / Reuters (free registration required)


Related Commentary on Twitter


Effect of Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions: A Randomized Clinical Trial – JAMA (free for a limited period)


Related Commentary on Twitter


Podcast: Update in Sleep Medicine

27 Nov, 2019 | 08:08h | UTC

Results of the Fontan Udenafil Exercise Longitudinal (FUEL) Trial – Circulation (free for a limited period)

Commentaries: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial – Children’s Hospital of Philadelphia (free) AND Pediatric drug trial finds benefit in teens with heart defect – NIH News Releases (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting


Related Commentary on Twitter


Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele – New England Journal of Medicine (link to abstract – $ for full-text)

Editorial: Realizing the Dream of Molecularly Targeted Therapies for Cystic Fibrosis (free)

Related Research: Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Three-drug combo improves lung function in most common genetic form of cystic fibrosis – UT Southwestern Medical Center (free)


Related Commentary on Twitter

Long-term survival and cause-specific mortality of patients newly diagnosed with tuberculosis in São Paulo state, Brazil, 2010–15: a population-based, longitudinal study – The Lancet Infectious Diseases (free) (via @otavio_ranzani see Tweet)

Invited Commentary: Tuberculosis: an instrument of early mortality in life course (free)


Related Commentary on Twitter


Is Mycobacterium tuberculosis infection life long? – The BMJ (free)

Commentaries: Tuberculous infection is not life-long in most people – University of Pennsylvania School of Medicine (free) AND In the absence of a true test for latent TB we need shorter, safer preventive treatments – The BMJ Opinion (free)


Related Commentary on Twitter


Update on Oral Appliance Therapy

23 Oct, 2019 | 07:21h | UTC

Podcast: Tuberculosis Updates

22 Oct, 2019 | 08:05h | UTC

Update on Management of Stable COPD

22 Oct, 2019 | 08:01h | UTC

Metoprolol for the Prevention of Acute Exacerbations of COPD – New England Journal of Medicine (link to abstract – $ for full-text)


Related Commentary on Twitter


Review: Ultrasonography of the Lung

10 Oct, 2019 | 09:07h | UTC

Supplement: Obstructive Sleep Apnea

4 Oct, 2019 | 07:54h | UTC

Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Added Benefit of Noninvasive Ventilation to High-Flow Nasal Oxygen to Prevent Reintubation in Higher-Risk Patients (free for a limited period)



Pathology of Vaping-Associated Lung Injury – New England Journal of Medicine (free)

Commentaries: Vaping-related lung injuries resemble chemical burns, study finds – STAT (free) AND U.S. doctors rule out pneumonia due to inhaled oil as cause of vaping injuries – Reuters (free) AND Lung Damage From Vaping Resembles Chemical Burns, Report Says – The New York Times (10 articles per month are free)

Related: CDC Report: 76.9% of Patients with Vaping-related Lung Illnesses Used a THC-Containing Product (free) AND Preliminary Report: Pulmonary Illness Related to E-Cigarette Use (free)


Related Commentary on Twitter

What are the respiratory effects of e-cigarettes? – The BMJ (free for a limited period)


Related Commentary on Twitter


Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Two immunotherapy drug combination offers chemotherapy-free option for advanced NSCLC – European Society for Medical Oncology (free) AND Nivolumab/Low-dose Ipilimumab: A Potential Chemotherapy-Sparing Option in Advanced NSCLC – Pharmacy Times (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona


Related Commentary on Twitter


Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care – Health Technology Assessment (free)

Source: Critical Care Reviews Newsletter

“A protocolized non-invasive weaning strategy did not reduce time to liberation from ventilation. However, patients who underwent non-invasive weaning had fewer days requiring IMV and required fewer antibiotics for respiratory infections.”


Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Quick Take: Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation – 2 Minute Medicine (free)

Related: It’s safest to avoid e-cigarettes altogether – unless vaping is helping you quit smoking – The Conversation (free)


Related Commentary on Twitter


NICE Guideline: Tuberculosis

13 Sep, 2019 | 08:27h | UTC