Chest Medicine

Trends and risk factors of mortality and disability adjusted life years for chronic respiratory diseases from 1990 to 2017: systematic analysis for the Global Burden of Disease Study 2017 – The BMJ (free)

Commentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)

 

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Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia – JAMA Internal Medicine (free for a limited period)

Editorial: Overuse of Broad-Spectrum Antibiotics for Pneumonia (free for a limited period)

 

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Management of Acute Asthma in Adults in 2020 – JAMA (free for a limited period)

Related Article: Outpatient Management of Chronic Asthma in 2020 – JAMA (free for a limited period)

Editorial: New Therapeutic Strategies for Asthma – JAMA (free for a limited period)

 


Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Related: Meta-Analysis: Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients with Moderate to Severe Acute Respiratory Distress Syndrome (free resources on the subject)

 

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Conservative versus Interventional Treatment for Spontaneous Pneumothorax – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: ‘Hands Off approach’ best to treat a collapsed lung – study – Voxy (free) AND Don’t Just Do Something, Stand There (Watching Spontaneous Pneumothoraces) – NEJM Journal Watch (free)

 

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Severe Flu Management: A Point of View

23 Jan, 2020 | 09:42h | UTC

E-cigarettes: how risky are they? – World Health Organization (free)

 

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Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: post-hoc safety analysis of two randomised controlled trials – The Lancet Infectious Diseases (free registration required)

Commentaries: What is the best regimen to treat latent tuberculosis infection? – The Lancet Infectious Diseases (free) AND Four Months of Rifampicin May Be Best Option for Latent TB – Medscape / Reuters (free registration required)

 

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Effect of Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions: A Randomized Clinical Trial – JAMA (free for a limited period)

 

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Podcast: Update in Sleep Medicine

27 Nov, 2019 | 08:08h | UTC

Results of the Fontan Udenafil Exercise Longitudinal (FUEL) Trial – Circulation (free for a limited period)

Commentaries: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial – Children’s Hospital of Philadelphia (free) AND Pediatric drug trial finds benefit in teens with heart defect – NIH News Releases (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

 

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Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele – New England Journal of Medicine (link to abstract – $ for full-text)

Editorial: Realizing the Dream of Molecularly Targeted Therapies for Cystic Fibrosis (free)

Related Research: Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Three-drug combo improves lung function in most common genetic form of cystic fibrosis – UT Southwestern Medical Center (free)

 

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Long-term survival and cause-specific mortality of patients newly diagnosed with tuberculosis in São Paulo state, Brazil, 2010–15: a population-based, longitudinal study – The Lancet Infectious Diseases (free) (via @otavio_ranzani see Tweet)

Invited Commentary: Tuberculosis: an instrument of early mortality in life course (free)

 

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Is Mycobacterium tuberculosis infection life long? – The BMJ (free)

Commentaries: Tuberculous infection is not life-long in most people – University of Pennsylvania School of Medicine (free) AND In the absence of a true test for latent TB we need shorter, safer preventive treatments – The BMJ Opinion (free)

 

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Update on Oral Appliance Therapy

23 Oct, 2019 | 07:21h | UTC

Podcast: Tuberculosis Updates

22 Oct, 2019 | 08:05h | UTC

Update on Management of Stable COPD

22 Oct, 2019 | 08:01h | UTC

Metoprolol for the Prevention of Acute Exacerbations of COPD – New England Journal of Medicine (link to abstract – $ for full-text)

 

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Review: Ultrasonography of the Lung

10 Oct, 2019 | 09:07h | UTC

Supplement: Obstructive Sleep Apnea

4 Oct, 2019 | 07:54h | UTC

Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Added Benefit of Noninvasive Ventilation to High-Flow Nasal Oxygen to Prevent Reintubation in Higher-Risk Patients (free for a limited period)

 

 


Pathology of Vaping-Associated Lung Injury – New England Journal of Medicine (free)

Commentaries: Vaping-related lung injuries resemble chemical burns, study finds – STAT (free) AND U.S. doctors rule out pneumonia due to inhaled oil as cause of vaping injuries – Reuters (free) AND Lung Damage From Vaping Resembles Chemical Burns, Report Says – The New York Times (10 articles per month are free)

Related: CDC Report: 76.9% of Patients with Vaping-related Lung Illnesses Used a THC-Containing Product (free) AND Preliminary Report: Pulmonary Illness Related to E-Cigarette Use (free)

 

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What are the respiratory effects of e-cigarettes? – The BMJ (free for a limited period)

 

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Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Two immunotherapy drug combination offers chemotherapy-free option for advanced NSCLC – European Society for Medical Oncology (free) AND Nivolumab/Low-dose Ipilimumab: A Potential Chemotherapy-Sparing Option in Advanced NSCLC – Pharmacy Times (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

 

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Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care – Health Technology Assessment (free)

Source: Critical Care Reviews Newsletter

“A protocolized non-invasive weaning strategy did not reduce time to liberation from ventilation. However, patients who underwent non-invasive weaning had fewer days requiring IMV and required fewer antibiotics for respiratory infections.”

 


Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Quick Take: Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation – 2 Minute Medicine (free)

Related: It’s safest to avoid e-cigarettes altogether – unless vaping is helping you quit smoking – The Conversation (free)

 

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NICE Guideline: Tuberculosis

13 Sep, 2019 | 08:27h | UTC